| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer C Miguel, Sylvia E Perez, Michael Malek-Ahmadi, Elliott J Mufso. Cerebellar Calcium-Binding Protein and Neurotrophin Receptor Defects in Down Syndrome and Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-05-11. PMID:33776745. |
cerebellar hypoplasia is a major characteristic of the down syndrome (ds) brain. |
2021-05-11 |
2023-08-13 |
Not clear |
| Saurav Mallik, Zhongming Zha. Detecting methylation signatures in neurodegenerative disease by density-based clustering of applications with reducing noise. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335112. |
we applied the framework to two representative neurodegenerative diseases, alzheimer's disease (ad) and down syndrome (ds), using dna methylation datasets from public sources (gene expression omnibus, geo accession id: gse74486). |
2021-05-10 |
2023-08-13 |
Not clear |
| Yamini J Howe, Robyn P Thom, Erin E Notson, Christopher J McDougle, Michelle L Palumb. Buspirone for the Treatment of Generalized Anxiety Disorder in Down Syndrome: 3 Cases. Journal of developmental and behavioral pediatrics : JDBP. 2021-05-09. PMID:33965971. |
reports on the pharmacologic treatment of anxiety, including generalized anxiety disorder (gad), in individuals with down syndrome (ds) are lacking. |
2021-05-09 |
2023-08-13 |
Not clear |
| Beatriz Helena Brugnaro, Maria Fernanda Pauletti Oliveira, Ana Carolina de Campos, Silvia Letícia Pavão, Nelci Adriana Cicuto Ferreira Roch. Postural control in Down syndrome and relationships with the dimensions of the International Classification of Functioning, Disability and Health - a systematic review. Disability and rehabilitation. 2021-05-07. PMID:33049152. |
postural control assessment in children with down syndrome (ds) may contribute to understanding the impact of impairments in body structures and functions on activities and participation, providing a biopsychosocial approach to support clinical practice. |
2021-05-07 |
2023-08-13 |
Not clear |
| M Stensson, J Norderyd, M Van Riper, L Marks, M Björ. Parents' perceptions of oral health, general health and dental health care for children with Down syndrome in Sweden. Acta odontologica Scandinavica. vol 79. issue 4. 2021-05-06. PMID:33017197. |
to describe parental perceptions of general health, oral health and received dental health care in swedish children with down syndrome (ds). |
2021-05-06 |
2023-08-13 |
Not clear |
| Audrey Landuran, Bernard N'Kaou. Prospective memory in adults with down syndrome. Applied neuropsychology. Adult. 2021-05-05. PMID:33044888. |
the objective of this work is to study the performance of people with down syndrome (ds) compared to two control groups, matched by mental age and chronological age. |
2021-05-05 |
2023-08-13 |
Not clear |
| b' Ver\\xc3\\xb3nica Vidal, Alba Puente, Susana Garc\\xc3\\xada-Cerro, Mar\\xc3\\xada Teresa Garc\\xc3\\xada Unzueta, Noem\\xc3\\xad Rueda, Javier Riancho, Carmen Mart\\xc3\\xadnez-Cu\\xc3\\xa. Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer\'s Disease. Frontiers in pharmacology. vol 12. 2021-05-04. PMID:33935706.' |
all individuals with down syndrome (ds) eventually develop alzheimer's disease (ad) neuropathology, including neurodegeneration, increases in |
2021-05-04 |
2023-08-13 |
mouse |
| George Capone, Mary Stephens, Stephanie Santoro, Brian Chicoine, Peter Bulova, Moya Peterson, Joan Jasien, Anna Jo Smit. Co-occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines. Part II. American journal of medical genetics. Part A. vol 182. issue 7. 2021-04-28. PMID:32338447. |
adults with down syndrome (ds) represent a unique population who are in need of clinical guidelines to address their medical care. |
2021-04-28 |
2023-08-13 |
human |
| Angelo Carfì, Allegra Romano, Giulia Zaccaria, Emanuele Rocco Villani, Ester Manes Gravina, Davide Liborio Vetrano, Roberto Bernabei, Graziano Onde. The burden of chronic disease, multimorbidity, and polypharmacy in adults with Down syndrome. American journal of medical genetics. Part A. vol 182. issue 7. 2021-04-28. PMID:32449279. |
data on clinical characteristics of adults with down syndrome (ds) are limited and the clinical phenotype of these persons is poorly described. |
2021-04-28 |
2023-08-13 |
human |
| Hakan Erenel, Riza Madazl. Pons Anteroposterior and Cerebellar Vermis Craniocaudal Diameters in Fetuses With Down Syndrome. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. vol 40. issue 1. 2021-04-28. PMID:32592425. |
to investigate the pons anteroposterior diameter (apd) and cerebellar vermis craniocaudal diameter (ccd) of fetuses with down syndrome (ds). |
2021-04-28 |
2023-08-13 |
Not clear |
| Mirko Kroll, Kirsten Kaupat-Bleckmann, Anja Mörickel, Julia Altenl, Denis M Schewel, Martin Stanullal, Martin Zimmermann, Martin Schrappe, Gunnar Cari. Methotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen. Haematologica. vol 105. issue 4. 2021-04-27. PMID:31371414. |
children with down syndrome (ds) and acute lymphoblastic leukemia (all) often suffer from severe toxicities during treatment, especially with high-dose methotrexate (hd-mtx). |
2021-04-27 |
2023-08-13 |
Not clear |
| Stephanie L Santoro, Sheila Cannon, George Capone, Cathy Franklin, Sarah J Hart, Victoria Hobensack, Priya S Kishnani, Eric A Macklin, Kandamurugu Manickam, Andrew McCormick, Patricia Nash, Nicolas M Oreskovic, Vasiliki Patsiogiannis, Katherine Steingass, Amy Torres, Diletta Valentini, Kishore Vellody, Brian G Skotk. Unexplained regression in Down syndrome: 35 cases from an international Down syndrome database. Genetics in medicine : official journal of the American College of Medical Genetics. vol 22. issue 4. 2021-04-27. PMID:31767984. |
an entity of regression in down syndrome (ds) exists that affects adolescents and young adults and differs from autism spectrum disorder and alzheimer disease. |
2021-04-27 |
2023-08-13 |
Not clear |
| Gurpreet S Dhillon, Nancy S Ghanayem, Christopher R Broda, Seema R Lalani, Carlos M Mery, Lara S Shekerdemian, Steven J Staffa, Shaine A Morri. An Analysis of Hospital Mortality After Cardiac Operations in Children With Down Syndrome. Seminars in thoracic and cardiovascular surgery. vol 32. issue 4. 2021-04-27. PMID:32621963. |
children with down syndrome (ds) have lower mortality compared to nonsyndromic (ns) children after atrioventricular septal defect (avsd) repair. |
2021-04-27 |
2023-08-13 |
Not clear |
| Anna Lee, George Knafl, Kathleen Knafl, Marcia Van Ripe. Parent-Reported Contribution of Family Variables to the Quality of Life in Children with Down Syndrome: Report from an International Study. Journal of pediatric nursing. vol 55. 2021-04-27. PMID:32957023. |
the intent of this study was to determine parents' views of the contribution of family variables to the quality of life (qol) of children with down syndrome (ds). |
2021-04-27 |
2023-08-13 |
Not clear |
| Daphna Shaw, Sari Bar, Jane Dimmitt Champio. The Impact of Developmental Behavioral Pediatrics in a Population of Children with Down Syndrome. Journal of pediatric nursing. vol 57. 2021-04-27. PMID:33212345. |
children with down syndrome (ds) have a unique developmental profile with an increased risk for co-morbid neurodevelopmental diagnoses, including autism spectrum disorder (asd), anxiety, and attention deficit/hyperactivity disorder (adhd), among others. |
2021-04-27 |
2023-08-13 |
Not clear |
| Shruti Mittal, Andrea D Boan, Silvia Pereira-Smith, Angela LaRos. Screening for Anemia in Children with Down Syndrome. Journal of developmental and behavioral pediatrics : JDBP. vol 41. issue 2. 2021-04-26. PMID:31593027. |
as part of the 2011 american academy of pediatrics (aap) health supervision guidelines for children with down syndrome (ds), annual screening for iron deficiency anemia is recommended between the ages of 1 and 18 years, but the evidence supporting this recommendation is limited. |
2021-04-26 |
2023-08-13 |
Not clear |
| Katsuya Hirata, Toshihiko Nambara, Keiji Kawatani, Nobutoshi Nawa, Hidetaka Yoshimatsu, Haruna Kusakabe, Kimihiko Banno, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Hidetoshi Taniguchi, Hitomi Arahori, Kazuko Wada, Keiichi Ozono, Yasuji Kitabatak. 4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates. Scientific reports. vol 10. issue 1. 2021-04-23. PMID:32820178. |
individuals with down syndrome (ds) commonly show unique pathological phenotypes throughout their life span. |
2021-04-23 |
2023-08-13 |
human |
| Ryohei Shimizu, Keiichi Ishihara, Eri Kawashita, Haruhiko Sago, Kazuhiro Yamakawa, Ken-Ichi Mizutani, Satoshi Akib. Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models. Biochemical and biophysical research communications. vol 535. 2021-04-21. PMID:33348080. |
down syndrome (ds, trisomy 21) is the most common genetic cause of delayed fetal brain development and postnatal intellectual disability. |
2021-04-21 |
2023-08-13 |
mouse |
| Shreyans Darla, Deepa Bha. Health-related quality of life and coping strategies among families with Down syndrome children in South India. Medical journal, Armed Forces India. vol 77. issue 2. 2021-04-21. PMID:33867636. |
down syndrome (ds) is the most common chromosomal disorder associated with intellectual disability. |
2021-04-21 |
2023-08-13 |
Not clear |
| Weili Shi, Fan Yang, Ranran Dai, Yafei Sun, Yan Chu, Shixiu Liao, Bingtao Ha. METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome. Frontiers in cell and developmental biology. vol 9. 2021-04-21. PMID:33869171. |
down syndrome (ds) is a common genetic condition in which a person is born with an extra copy of chromosome 21. |
2021-04-21 |
2023-08-13 |
human |