| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryohei Shimizu, Keiichi Ishihara, Eri Kawashita, Haruhiko Sago, Kazuhiro Yamakawa, Ken-Ichi Mizutani, Satoshi Akib. Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models. Biochemical and biophysical research communications. vol 535. 2021-04-21. PMID:33348080. |
down syndrome (ds, trisomy 21) is the most common genetic cause of delayed fetal brain development and postnatal intellectual disability. |
2021-04-21 |
2023-08-13 |
mouse |
| Shreyans Darla, Deepa Bha. Health-related quality of life and coping strategies among families with Down syndrome children in South India. Medical journal, Armed Forces India. vol 77. issue 2. 2021-04-21. PMID:33867636. |
down syndrome (ds) is the most common chromosomal disorder associated with intellectual disability. |
2021-04-21 |
2023-08-13 |
Not clear |
| Weili Shi, Fan Yang, Ranran Dai, Yafei Sun, Yan Chu, Shixiu Liao, Bingtao Ha. METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome. Frontiers in cell and developmental biology. vol 9. 2021-04-21. PMID:33869171. |
down syndrome (ds) is a common genetic condition in which a person is born with an extra copy of chromosome 21. |
2021-04-21 |
2023-08-13 |
human |
| Zhu-Ming Hu, Li-Li Luo, Ling Li, Si-Da Dai, Hong-Guo Zhang, Rui-Zhi Li. Indigenization of the median of markers for Down syndrome screening based on statistical analysis of medical big data. Taiwanese journal of obstetrics & gynecology. vol 59. issue 4. 2021-04-20. PMID:32653129. |
to indigenize the median of down syndrome (ds) screening markers for first and second trimester, and compare the impact of the indigenized and built-in median data on the efficiency of ds screening. |
2021-04-20 |
2023-08-13 |
Not clear |
| Elizabeth A Hill, Donna M Fairley, Ewan McConnell, Ian Morrison, Marta Celmina, Serafeim-Chrysovalantis Kotoulas, Renata L Rih. Utility of the pictorial Epworth sleepiness scale in the adult down syndrome population. Sleep medicine. vol 66. 2021-04-19. PMID:31877508. |
the aim of this study was to assess the utility of the pess in the adult down syndrome (ds) population in the united kingdom (uk). |
2021-04-19 |
2023-08-13 |
Not clear |
| Maire E Percy, Walter J Luki. Is heart disease a risk factor for low dementia test battery scores in older persons with Down syndrome? Exploratory, pilot study, and commentary. International journal of developmental disabilities. vol 66. issue 1. 2021-04-18. PMID:33859818. |
certain heart conditions and diseases are common in down syndrome (ds; trisomy 21), but their role in early onset dementia that is prevalent in older adults with ds has not been evaluated. |
2021-04-18 |
2023-08-13 |
human |
| Yasuhiro Kazuki, Feng J Gao, Yicong Li, Anna J Moyer, Benjamin Devenney, Kei Hiramatsu, Sachiko Miyagawa-Tomita, Satoshi Abe, Kanako Kazuki, Naoyo Kajitani, Narumi Uno, Shoko Takehara, Masato Takiguchi, Miho Yamakawa, Atsushi Hasegawa, Ritsuko Shimizu, Satoko Matsukura, Naohiro Noda, Narumi Ogonuki, Kimiko Inoue, Shogo Matoba, Atsuo Ogura, Liliana D Florea, Alena Savonenko, Meifang Xiao, Dan Wu, Denise As Batista, Junhua Yang, Zhaozhu Qiu, Nandini Singh, Joan T Richtsmeier, Takashi Takeuchi, Mitsuo Oshimura, Roger H Reeve. A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21. eLife. vol 9. 2021-04-16. PMID:32597754. |
animal models of down syndrome (ds), trisomic for human chromosome 21 (hsa21) genes or orthologs, provide insights into better understanding and treatment options. |
2021-04-16 |
2023-08-13 |
mouse |
| Matthew D Zammit, Charles M Laymon, Tobey J Betthauser, Karly A Cody, Dana L Tudorascu, Davneet S Minhas, Marwan N Sabbagh, Sterling C Johnson, Shahid H Zaman, Chester A Mathis, William E Klunk, Benjamin L Handen, Ann D Cohen, Bradley T Christia. Amyloid accumulation in Down syndrome measured with amyloid load. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-04-13. PMID:32435686. |
individuals with down syndrome (ds) show enhanced amyloid beta (aβ) deposition in the brain. |
2021-04-13 |
2023-08-13 |
Not clear |
| Ewa Parfieniuk, Karolina Pietrowska, Paulina Samczuk, Adam Kretowski, Michal Ciborowski, Monika Zbucka-Kretowsk. Amniotic fluid metabolic fingerprinting indicated metabolites which may play a role in the pathogenesis of foetal Down syndrome - a preliminary report. Ginekologia polska. vol 92. issue 3. 2021-04-13. PMID:33576476. |
the objective of this study was to determine the metabolic fingerprinting of the amniotic fluid women carrying foetuses with down syndrome (ds). |
2021-04-13 |
2023-08-13 |
human |
| María Dolores Figueroa-Jimenez, María Carbó-Carreté, Cristina Cañete-Massé, Daniel Zarabozo-Hurtado, Maribel Peró-Cebollero, José Guadalupe Salazar-Estrada, Joan Guàrdia-Olmo. Complexity Analysis of the Default Mode Network Using Resting-State fMRI in Down Syndrome: Relationships Highlighted by a Neuropsychological Assessment. Brain sciences. vol 11. issue 3. 2021-04-13. PMID:33801471. |
studies on complexity indicators in the field of functional connectivity derived from resting-state fmri (rs-fmri) in down syndrome (ds) samples and their possible relationship with cognitive functioning variables are rare. |
2021-04-13 |
2023-08-13 |
Not clear |
| Iris Scala, Daniela Valenti, Valentina Scotto D'Aniello, Maria Marino, Maria Pia Riccio, Carmela Bravaccio, Rosa Anna Vacca, Pietro Strisciugli. Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F Antioxidants (Basel, Switzerland). vol 10. issue 3. 2021-04-13. PMID:33809669. |
epigallocatechin-3-gallate plus omega-3 restores the mitochondrial complex i and f down syndrome (ds) is a major genetic cause of intellectual disability. |
2021-04-13 |
2023-08-13 |
Not clear |
| Chiara Meneghetti, Enrico Toffalini, Silvia Lanfranchi, Maja Roch, Barbara Carrett. Path Learning in Individuals With Down Syndrome: The Challenge of Learning Condition and Cognitive Abilities. Frontiers in psychology. vol 12. 2021-04-13. PMID:33841279. |
analyzing navigational abilities and related aspects in individuals with down syndrome (ds) is of considerable interest because of its relevance to everyday life. |
2021-04-13 |
2023-08-13 |
human |
| Laura Reiche, Peter Göttle, Lydie Lane, Paula Duek, Mina Park, Kasum Azim, Jana Schütte, Anastasia Manousi, Jessica Schira-Heinen, Patrick Kür. C21orf91 Regulates Oligodendroglial Precursor Cell Fate-A Switch in the Glial Lineage? Frontiers in cellular neuroscience. vol 15. 2021-04-03. PMID:33796011. |
down syndrome (ds), or trisomy 21, is the most common genetic cause for cognitive impairments and intellectual disability (id) and is associated with a reduction in the number of neurons and oligodendrocytes, as well as with hypomyelination and astrogliosis. |
2021-04-03 |
2023-08-13 |
Not clear |
| Emily Mason-Apps, Vesna Stojanovik, Carmel Houston-Price, Emily Seager, Sue Buckle. Do Infants With Down Syndrome Show an Early Receptive Language Advantage? Journal of speech, language, and hearing research : JSLHR. vol 63. issue 2. 2021-03-29. PMID:32091963. |
purpose the study explored longitudinally the course of vocabulary and general language development in a group of infants with down syndrome (ds) compared to a group of typically developing (td) infants matched on nonverbal mental ability (nvma). |
2021-03-29 |
2023-08-13 |
Not clear |
| Aimée Freeburn, Robert Gordon Keith Mun. Signalling pathways contributing to learning and memory deficits in the Ts65Dn mouse model of Down syndrome. Neuronal signaling. vol 5. issue 1. 2021-03-26. PMID:33763235. |
down syndrome (ds) is a genetic trisomic disorder that produces life-long changes in physiology and cognition. |
2021-03-26 |
2023-08-13 |
mouse |
| Yannick Dieudonné, Beatrice Uring-Lambert, Mohamed Maxime Jeljeli, Vincent Gies, Yves Alembik, Anne-Sophie Korganow, Aurélien Guffro. Immune Defect in Adults With Down Syndrome: Insights Into a Complex Issue. Frontiers in immunology. vol 11. 2021-03-25. PMID:32457756. |
children with down syndrome (ds) suffer from recurrent respiratory infections, which represent the leading cause of mortality during childhood. |
2021-03-25 |
2023-08-13 |
Not clear |
| Beatrice Uguagliati, Abdel-Rahman Al-Absi, Fiorenza Stagni, Marco Emili, Andrea Giacomini, Sandra Guidi, Jens Randel Nyengaard, Renata Bartesagh. Early appearance of developmental alterations in the dendritic tree of the hippocampal granule cells in the Ts65Dn model of Down syndrome. Hippocampus. vol 31. issue 4. 2021-03-25. PMID:33464704. |
down syndrome (ds), a genetic condition caused by triplication of chromosome 21, is characterized by alterations in various cognitive domains, including hippocampus-dependent memory functions, starting from early life stages. |
2021-03-25 |
2023-08-13 |
mouse |
| Benjamin I Laufer, J Antonio Gomez, Julia M Jianu, Janine M LaSall. Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature. Epigenetics & chromatin. vol 14. issue 1. 2021-03-25. PMID:33750431. |
down syndrome (ds) is characterized by a genome-wide profile of differential dna methylation that is skewed towards hypermethylation in most tissues, including brain, and includes pan-tissue differential methylation. |
2021-03-25 |
2023-08-13 |
human |
| Tomo Tarui, Kiho Im, Neel Madan, Rajeevi Madankumar, Brian G Skotko, Allie Schwartz, Christianne Sharr, Steven J Ralston, Rie Kitano, Shizuko Akiyama, Hyuk Jin Yun, Ellen Grant, Diana W Bianch. Quantitative MRI Analyses of Regional Brain Growth in Living Fetuses with Down Syndrome. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 1. 2021-03-22. PMID:31264685. |
down syndrome (ds) is the most common liveborn autosomal chromosomal anomaly and is a major cause of developmental disability. |
2021-03-22 |
2023-08-13 |
human |
| Cristina E Trevino, Aaron M Holleman, Holly Corbitt, Cheryl L Maslen, Tracie C Rosser, David J Cutler, H Richard Johnston, Benjamin L Rambo-Martin, Jai Oberoi, Kenneth J Dooley, George T Capone, Roger H Reeves, Heather J Cordell, Bernard D Keavney, A J Agopian, Elizabeth Goldmuntz, Peter J Gruber, James E O'Brien, Douglas C Bittel, Lalita Wadhwa, Clifford L Cua, Ivan P Moskowitz, Jennifer G Mulle, Michael P Epstein, Stephanie L Sherman, Michael E Zwic. Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome. Scientific reports. vol 10. issue 1. 2021-03-22. PMID:33093519. |
atrioventricular septal defects (avsd) are a severe congenital heart defect present in individuals with down syndrome (ds) at a > 2000-fold increased prevalence compared to the general population. |
2021-03-22 |
2023-08-13 |
Not clear |