| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| François Poumeaud, Clotilde Mircher, Peter J Smith, Pierre-Antoine Faye, Franck G Sturt. Deciphering the links between psychological stress, depression, and neurocognitive decline in patients with Down syndrome. Neurobiology of stress. vol 14. 2021-02-23. PMID:33614867. |
clinically, we noticed that patients with down syndrome (ds) may develop rapid neurocognitive decline and alzheimer's disease (ad) earlier than expected, often shortly after a traumatic life event (bereavement over the leave of a primary caregiver, an assault, modification of lifestyle, or the loss of parents). |
2021-02-23 |
2023-08-13 |
Not clear |
| Miao Wei, Natasha Lepore, Kelli Paulsen, Jonathan D Santor. Down syndrome with co-occurring Marfan syndrome. BMJ case reports. vol 13. issue 9. 2021-02-22. PMID:32967946. |
down syndrome (ds) and marfan syndrome (mfs) are two unique genetic disorders that share limited phenotypic overlap. |
2021-02-22 |
2023-08-13 |
Not clear |
| Mary Godfrey, Nancy Raitano Le. A comprehensive examination of the memory profile of youth with Down syndrome in comparison to typically developing peers. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. vol 26. issue 6. 2021-02-18. PMID:32100621. |
down syndrome (ds) is associated with significant memory deficits beyond overall global cognitive impairment. |
2021-02-18 |
2023-08-13 |
Not clear |
| Gabriela Neves Nunes, Stephanie Santana Pinto, Gabriele Randuz Krüger, Leonardo Alexandre Peyré-Tartaruga, Luana Siqueira Andrade, Graciele Ferreira Mendes, Vitor de Lima Krüger, Rochele Barboza Pinheiro, Alexandre Carriconde Marques, Cristine Lima Alberto. Kinetic parameters during land and water walking performed by individuals with Down Syndrome. Gait & posture. vol 79. 2021-02-18. PMID:32361126. |
down syndrome (ds) is a genetic condition presenting delay in acquisition of main motor milestones, such as walking. |
2021-02-18 |
2023-08-13 |
Not clear |
| Iveta Zedníková, Blanka Chylíková, Ondřej Šeda, Marie Korabečná, Eva Pazourková, Miroslav Břešťák, Miroslava Krkavcová, Pavel Calda, Aleš Hoříne. Genome-wide miRNA profiling in plasma of pregnant women with down syndrome fetuses. Molecular biology reports. vol 47. issue 6. 2021-02-18. PMID:32472298. |
down syndrome (ds) is one of the most common causes of intellectual disability and new approaches allowing its rapid and effective prenatal detection are being explored. |
2021-02-18 |
2023-08-13 |
Not clear |
| Lauren T Ptomey, Amanda N Szabo-Reed, Laura E Martin, Matthew S Mayo, Richard A Washburn, Anna M Gorczyca, Rebecca J Lepping, Phill Lee, Daniel E Forsha, Joseph R Sherman, Jessica C Danon, Joseph E Donnell. The promotion of physical activity for the prevention of Alzheimer's disease in adults with Down Syndrome: Rationale and design for a 12 Month randomized trial. Contemporary clinical trials communications. vol 19. 2021-02-17. PMID:32642594. |
nearly all individuals with down syndrome (ds) display pathology associated with alzheimer's disease (ad) beginning as early as age 30. |
2021-02-17 |
2023-08-13 |
Not clear |
| Robertina Giacconi, Fabrizio Maggi, Lisa Macera, Pietro Giorgio Spezia, Mauro Pistello, Mauro Provinciali, Francesco Piacenza, Andrea Basso, Alexander Bürkle, María Moreno-Villanueva, Martijn E T Dollé, Eugène Jansen, Tilman Grune, Wolfgang Stuetz, Efstathios S Gonos, Christiane Schön, Jürgen Bernhardt, Beatrix Grubeck-Loebenstein, Ewa Sikora, Magdalena Dudkowska, Dorota Janiszewska, Olivier Toussaint, Florence Debacq-Chainiaux, Claudio Franceschi, Miriam Capri, Antti Hervonen, Mikko Hurme, Eline Slagboom, Nicolle Breusing, Eugenio Mocchegiani, Marco Malavolt. Prevalence and Loads of Torquetenovirus in the European MARK-AGE Study Population. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 75. issue 10. 2021-02-16. PMID:31838498. |
we compared levels of circulating ttv in 1813 participants of the mark-age project, including human models of delayed (offspring of centenarians [go]) and premature (down syndrome [ds]) immunosenescence. |
2021-02-16 |
2023-08-13 |
human |
| Serena Vita, Virginia Di Bari, Angela Corpolongo, Delia Goletti, Joaquin Espinosa, Sebastiano Petracca, Fabrizio Palmieri, Emanuele Nicastr. Down Syndrome patients with COVID-19 pneumonia: A high-risk category for unfavourable outcome. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. vol 103. 2021-02-16. PMID:33271290. |
we report two cases of corona virus disease-19 (covid-19) in patients with down syndrome (ds) and describe the identification, diagnosis, clinical course and management of the infection. |
2021-02-16 |
2023-08-13 |
Not clear |
| Ilario De Toma, Mara Diersse. Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19. Scientific reports. vol 11. issue 1. 2021-02-16. PMID:33479353. |
sars-cov-2 infection has spread uncontrollably worldwide while it remains unknown how vulnerable populations, such as down syndrome (ds) individuals are affected by the covid-19 pandemic. |
2021-02-16 |
2023-08-13 |
Not clear |
| Abdullah N Alhuzaimi, Najoud M Alotaibi, Ghadah I Alsuhaibani, Reem K Alanazi, Mohamad-Hani Temsa. Congenital Heart Defect and Pulmonary Hypertension in Children With Down Syndrome: Clinical Profile Over Two Decades. Cureus. vol 13. issue 2. 2021-02-16. PMID:33585145. |
to describe the frequency and spectrum of congenital heart defects (chd) and pulmonary hypertension among pediatric patients with down syndrome (ds) in saudi arabia. |
2021-02-16 |
2023-08-13 |
Not clear |
| Manuela D Mitsogiannis, Anna Pancho, Tania Aerts, Sonja M Sachse, Ria Vanlaer, Lut Noterdaeme, Dietmar Schmucker, Eve Seuntjen. Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Frontiers in cell and developmental biology. vol 8. 2021-02-16. PMID:33585465. |
down syndrome (ds) cell adhesion molecules (dscams) are transmembrane proteins of the immunoglobulin superfamily. |
2021-02-16 |
2023-08-13 |
mouse |
| Manuela D Mitsogiannis, Anna Pancho, Tania Aerts, Sonja M Sachse, Ria Vanlaer, Lut Noterdaeme, Dietmar Schmucker, Eve Seuntjen. Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Frontiers in cell and developmental biology. vol 8. 2021-02-16. PMID:33585465. |
human dscam is located within the ds critical region of chromosome 21 (duplicated in down syndrome patients), and mutations or copy-number variations of this gene have also been associated to fragile x syndrome, intellectual disability, autism, and bipolar disorder. |
2021-02-16 |
2023-08-13 |
mouse |
| Ibrahim Alsahabi, Abdulaziz Alobaidi, Ayman S Alahmari, Noof Almohsen, Abdullah H Alhamou. Clinical Presentation and Successful Management of an Infant With Down Syndrome and COVID-19 in Riyadh, Saudi Arabia. Cureus. vol 13. issue 2. 2021-02-13. PMID:33575158. |
down syndrome (ds) is characterized by immune dysregulation, has various anatomical variations, and is considered as comorbidity. |
2021-02-13 |
2023-08-13 |
Not clear |
| Javier Zorrilla de San Martin, Cristina Donato, Jérémy Peixoto, Andrea Aguirre, Vikash Choudhary, Angela Michela De Stasi, Joana Lourenço, Marie-Claude Potier, Alberto Bacc. Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome. eLife. vol 9. 2021-02-11. PMID:32783810. |
down syndrome (ds) results in various degrees of cognitive deficits. |
2021-02-11 |
2023-08-13 |
mouse |
| Reinhard E Friedrich, Felix K Kohlrusch, Ulrich Grzysk. Vestiges of Ossified Spheno-occipital Suture in an Elderly Patient With Down Syndrome and Lateral Skull Base Fracture. In vivo (Athens, Greece). vol 34. issue 3. 2021-02-10. PMID:32354941. |
down syndrome (ds) patients often show characteristic changes in the skull, e.g. |
2021-02-10 |
2023-08-13 |
Not clear |
| Naiyana Boontan, Kitiwan Rojnueangni. Growth Patterns of Thai Children with Down Syndrome from Birth to 5 Years. Journal of pediatric genetics. vol 10. issue 1. 2021-02-10. PMID:33552633. |
specific growth charts for children with down syndrome (ds) have been developed in several countries, but not in thailand. |
2021-02-10 |
2023-08-13 |
Not clear |
| Nunzia Mollo, Rita Cicatiello, Miriam Aurilia, Roberta Scognamiglio, Rita Genesio, Maria Charalambous, Simona Paladino, Anna Conti, Lucio Nitsch, Antonella Izz. Targeting Mitochondrial Network Architecture in Down Syndrome and Aging. International journal of molecular sciences. vol 21. issue 9. 2021-02-09. PMID:32365535. |
a decline in mitochondrial quality, which presents itself as an altered structural organization and a function of mitochondria, has been observed in down syndrome (ds), as well as in aging and in age-related pathologies. |
2021-02-09 |
2023-08-13 |
Not clear |
| Hana D'Souza, Amanda Lathan, Annette Karmiloff-Smith, Denis Marescha. Down syndrome and parental depression: A double hit on early expressive language development. Research in developmental disabilities. vol 100. 2021-02-08. PMID:32192950. |
down syndrome (ds) is often characterised by intellectual disability with particular difficulties in expressive language. |
2021-02-08 |
2023-08-13 |
Not clear |
| Benjamin L Handen, Ira T Lott, Bradley T Christian, Nicole Schupf, Sid OBryant, Mark Mapstone, Anne M Fagan, Joseph H Lee, Dana Tudorascu, Mei-Cheng Wang, Elizabeth Head, William Klunk, Beau Ances, Florence Lai, Shahid Zaman, Sharon Krinsky-McHale, Adam M Brickman, H Diana Rosas, Annie Cohen, Howard Andrews, Sigan Hartley, Wayne Silverma. The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-02-06. PMID:32775597. |
adults with down syndrome (ds) are at exceptionally high risk for alzheimer's disease (ad), with virtually all individuals developing key neuropathological features by age 40. |
2021-02-06 |
2023-08-13 |
Not clear |
| Florence Lai, Pooja G Mhatre, Yuchen Yang, Mei-Cheng Wang, Nicole Schupf, H Diana Rosa. Sex differences in risk of Alzheimer's disease in adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 12. issue 1. 2021-02-06. PMID:32995462. |
adults with down syndrome (ds) older than 40 have alzheimer's disease (ad) neuropathology and high risk for dementia, but little is known about the relationship of sex to ad risk in this population. |
2021-02-06 |
2023-08-13 |
Not clear |