| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A-G Linossier, B Martinez, C-Y Valenzuel. Quantitative interactions between Candida albicans and the mutans streptococci in patients with Down Syndrome. Medicina oral, patologia oral y cirugia bucal. vol 26. issue 1. 2021-01-01. PMID:33247579. |
aim to study the quantitative interactions between c. albicans and the mutans streptococci and ms serotypes in the saliva of the oral cavity of patients with down syndrome (ds). |
2021-01-01 |
2023-08-13 |
Not clear |
| Takako Takano, Kazuhiko Nakabayashi, Hideomi Ota, Yasuhiro Arai, Hiromi Kamura, Kenichiro Hat. Tetrasomy 21 pter→q21.3 due to an extra +dic(21;21)mat in a severely psychomotor-retarded female patient without Down syndrome phenotype. European journal of medical genetics. vol 63. issue 4. 2020-12-31. PMID:31830537. |
the patient had severe psychomotor retardation without down syndrome (ds) phenotype; she showed short stature, microcephaly, round face, cleft lip and palate, and other dysmorphic features. |
2020-12-31 |
2023-08-13 |
Not clear |
| Angelika Buczyńska, Iwona Sidorkiewicz, Sławomir Ławicki, Adam Krętowski, Monika Zbucka-Krętowsk. The Significance of Apolipoprotein E Measurement in the Screening of Fetal Down Syndrome. Journal of clinical medicine. vol 9. issue 12. 2020-12-29. PMID:33321701. |
prenatal screening for down syndrome (ds) is based on both noninvasive and invasive methods. |
2020-12-29 |
2023-08-13 |
human |
| Ahmad Kantar, Angelo Mazza, Ezio Bonanomi, Marta Odoni, Manuela Seminara, Ilaria Dalla Verde, Camillo Lovati, Stefania Bolognini, Lorenzo D'Antig. COVID-19 and children with Down syndrome: is there any real reason to worry? Two case reports with severe course. BMC pediatrics. vol 20. issue 1. 2020-12-29. PMID:33339516. |
down syndrome (ds) is characterized by a series of immune dysregulations, of which interferon hyperreactivity is important, as it is responsible for surging antiviral responses and the possible initiation of an amplified cytokine storm. |
2020-12-29 |
2023-08-13 |
Not clear |
| Koviljka Barisnikov, Marine Thomasson, Jennyfer Stutzmann, Fleur Lejeun. Relation between processing facial identity and emotional expression in typically developing school-age children and those with Down syndrome. Applied neuropsychology. Child. vol 9. issue 2. 2020-12-28. PMID:30646753. |
study 2 compared 22 children with down syndrome (ds) to two td groups matched on mental age (ma group) and chronological age (ca group). |
2020-12-28 |
2023-08-13 |
Not clear |
| Alexandra Ilacqua, Jason Benedict, Abigail Shoben, Brian G Skotko, Theodora Matthews, Betsey Benson, Dawn C Allai. Alzheimer's disease development in adults with Down syndrome: Caregivers' perspectives. American journal of medical genetics. Part A. vol 182. issue 1. 2020-12-28. PMID:31639281. |
research about alzheimer's disease (ad) in individuals with down syndrome (ds) has predominantly focused on the underlying genetics and neuropathology. |
2020-12-28 |
2023-08-13 |
Not clear |
| Stina Lou, Maja Retpen Lanther, Natascha Hagenstjerne, Olav Bjørn Petersen, Ida Voge. "This is the child we were given": A qualitative study of Danish parents' experiences of a prenatal Down syndrome diagnosis and their decision to continue the pregnancy. Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives. vol 23. 2020-12-28. PMID:31733609. |
termination rates when down syndrome (ds) is diagnosed prenatally are high in most countries. |
2020-12-28 |
2023-08-13 |
Not clear |
| Francine A van den Driessen Mareeuw, Antonia M W Coppus, Diana M J Delnoij, Esther de Vrie. Capturing the complexity of healthcare for people with Down syndrome in quality indicators - a Delphi study involving healthcare professionals and patient organisations. BMC health services research. vol 20. issue 1. 2020-12-23. PMID:32718322. |
insight into quality of healthcare for people with down syndrome (ds) is limited. |
2020-12-23 |
2023-08-13 |
human |
| Wei-Quan Fang, Wuh-Liang Hwu, Yin-Hsiu Chien, Shieh-Yueh Yang, Jen-Jie Chieh, Lih-Maan Chang, Ai-Chu Huang, Ni-Chung Lee, Ming-Jang Chi. Composite Scores of Plasma Tau and β-Amyloids Correlate with Dementia in Down Syndrome. ACS chemical neuroscience. vol 11. issue 2. 2020-12-21. PMID:31799825. |
dementia frequently occurs in down syndrome (ds) patients, and early intervention is important in its management. |
2020-12-21 |
2023-08-13 |
Not clear |
| María Martínez de Lagrá. Mapping behavioral landscapes in Down syndrome animal models. Progress in brain research. vol 251. 2020-12-21. PMID:32057306. |
down syndrome (ds), caused by trisomy of chromosome 21 (hsa21), results in a spectrum of phenotypes including learning and memory deficits, motor dysfunction and social constrains. |
2020-12-21 |
2023-08-13 |
mouse |
| Y Eugene Yu, Zhuo Xing, Catherine Do, Annie Pao, Eun Joon Lee, Sharon Krinsky-McHale, Wayne Silverman, Nicole Schupf, Benjamin Tyck. Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models. Progress in brain research. vol 251. 2020-12-21. PMID:32057305. |
the presence of an extra copy of human chromosome 21 (hsa21) leads to a constellation of phenotypic manifestations in down syndrome (ds), including prominent effects on the brain and immune system. |
2020-12-21 |
2023-08-13 |
mouse |
| Alexandra Botté, Marie-Claude Potie. Focusing on cellular biomarkers: The endo-lysosomal pathway in Down syndrome. Progress in brain research. vol 251. 2020-12-21. PMID:32057308. |
down syndrome (ds) is the most frequent chromosomal disorder. |
2020-12-21 |
2023-08-13 |
human |
| b' Noem\\xc3\\xad Rueda, Jes\\xc3\\xbas Fl\\xc3\\xb3rez, Mara Dierssen, Carmen Mart\\xc3\\xadnez-Cu\\xc3\\xa. Translational validity and implications of pharmacotherapies in preclinical models of Down syndrome. Progress in brain research. vol 251. 2020-12-21. PMID:32057309.' |
in the last two decades, diverse new murine models of down syndrome (ds) have been developed and numerous studies have demonstrated neurobiological alterations that could be responsible for the cognitive and behavioral phenotypes found in this syndrome. |
2020-12-21 |
2023-08-13 |
mouse |
| Carmen Martínez Cué, Mara Diersse. Plasticity as a therapeutic target for improving cognition and behavior in Down syndrome. Progress in brain research. vol 251. 2020-12-21. PMID:32057310. |
early intervention and environmental optimization have been central to management of down syndrome (ds) and much of current treatment is still focused in strategies that involve early education plans. |
2020-12-21 |
2023-08-13 |
Not clear |
| Gillian Gough, Niamh L O'Brien, Ivan Alic, Pollyanna A Goh, Yee Jie Yeap, Jurgen Groet, Dean Nizetic, Aoife Murra. Modeling Down syndrome in cells: From stem cells to organoids. Progress in brain research. vol 251. 2020-12-21. PMID:32057312. |
down syndrome (ds) is a complex chromosomal disorder, with neurological issues, featuring among the symptoms. |
2020-12-21 |
2023-08-13 |
mouse |
| Maria Del Mar Muñiz Moreno, Véronique Brault, Marie-Christine Birling, Guillaume Pavlovic, Yann Heraul. Modeling Down syndrome in animals from the early stage to the 4.0 models and next. Progress in brain research. vol 251. 2020-12-21. PMID:32057313. |
the genotype-phenotype relationship and the physiopathology of down syndrome (ds) have been explored in the last 20 years with more and more relevant mouse models. |
2020-12-21 |
2023-08-13 |
mouse |
| Randall J Roper, Laura Hawley, Charles R Goodlet. Influence of allelic differences in Down syndrome. Progress in brain research. vol 251. 2020-12-21. PMID:32057311. |
both trisomic and non-trisomic genes may affect the incidence and severity of phenotypes associated with down syndrome (ds). |
2020-12-21 |
2023-08-13 |
mouse |
| Patrick J Lao, José Gutierrez, David Keator, Batool Rizvi, Arit Banerjee, Kay C Igwe, Krystal K Laing, Mithra Sathishkumar, Fahmida Moni, Howard Andrews, Sharon Krinsky-McHale, Elizabeth Head, Joseph H Lee, Florence Lai, Michael A Yassa, H Diana Rosas, Wayne Silverman, Ira T Lott, Nicole Schupf, Adam M Brickma. Alzheimer-Related Cerebrovascular Disease in Down Syndrome. Annals of neurology. vol 88. issue 6. 2020-12-21. PMID:32944999. |
adults with down syndrome (ds) develop alzheimer disease (ad) pathology by their 5th decade. |
2020-12-21 |
2023-08-13 |
Not clear |
| Shengran Wang, Xia Tang, Litao Qin, Weili Shi, Shasha Bian, Zhaokun Wang, Qingqing Wang, Xin Wang, Jianqin Gu, Bingtao Hao, Keyue Ding, Shixiu Lia. Integrative Analysis Extracts a Core ceRNA Network of the Fetal Hippocampus With Down Syndrome. Frontiers in genetics. vol 11. 2020-12-18. PMID:33329702. |
interestingly, neuropathological changes that closely resemble ad have been found in nearly all down syndrome (ds) cases > 35 years. |
2020-12-18 |
2023-08-13 |
Not clear |
| Prachi A Patkee, Ana A Baburamani, Vanessa Kyriakopoulou, Alice Davidson, Elhaam Avini, Ralica Dimitrova, Joanna Allsop, Emer Hughes, Johanna Kangas, Grainne McAlonan, Mary A Rutherfor. Early alterations in cortical and cerebellar regional brain growth in Down Syndrome: An in vivo fetal and neonatal MRI assessment. NeuroImage. Clinical. vol 25. 2020-12-17. PMID:31887718. |
down syndrome (ds) is the most frequent genetic cause of intellectual disability with a wide spectrum of neurodevelopmental outcomes. |
2020-12-17 |
2023-08-13 |
human |