| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yujiro Matsuishi, Hideaki Sakuramoto, Haruhiko Hoshino, Nobutake Shimojo, Yuki Enomoto, Bryan J Mathis, Yuji Hiramatsu, Yoshiaki Inou. Down Syndrome Reduces the Sedative Effect of Midazolam in Pediatric Cardiovascular Surgical Patients. Scientific reports. vol 10. issue 1. 2020-11-12. PMID:32041972. |
down syndrome (ds) is frequently comorbid with congenital heart disease and has recently been shown to reduce the sedative effect of benzodiazepine (bdz)-class anesthesia but this effect in a clinical setting has not been studied. |
2020-11-12 |
2023-08-13 |
Not clear |
| Christopher Tomlinson, Alastair Campbell, Alison Hurley, Eoin Fenton, Neil Hero. Sport Preparticipation Screening for Asymptomatic Atlantoaxial Instability in Patients With Down Syndrome. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine. vol 30. issue 4. 2020-11-10. PMID:30119085. |
down syndrome (ds) is a clinical syndrome comprising typical facial features and various physical and intellectual disabilities due to extra genetic material on chromosome 21, with one in every 1000 babies born in the united kingdom affected. |
2020-11-10 |
2023-08-13 |
Not clear |
| Yang Du, Lei Chen, Yuguo Jiao, Yong Chen. Cerebrospinal fluid and blood Aβ levels in Down syndrome patients with and without dementia: a meta-analysis study. Aging. vol 11. issue 24. 2020-11-10. PMID:31860872. |
abnormal β-amyloid (aβ) levels were found in patients with down syndrome (ds). |
2020-11-10 |
2023-08-13 |
Not clear |
| Hyunkyung Choi, Marcia Van Ripe. mHealth Family Adaptation Intervention for Families of Young Children with Down Syndrome: A Feasibility Study. Journal of pediatric nursing. vol 50. 2020-11-09. PMID:30928311. |
the aim of this study was to explore the feasibility of using the mhealth family adaptation intervention (familyadapt-ds), with families of young children with down syndrome (ds), and to assess the effect of participating in this mhealth intervention on family adaptation. |
2020-11-09 |
2023-08-13 |
Not clear |
| A Ravel, C Mircher, A-S Rebillat, C Cieuta-Walti, A Megarban. Feeding problems and gastrointestinal diseases in Down syndrome. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. vol 27. issue 1. 2020-11-09. PMID:31784293. |
feeding problems and gastrointestinal disorders are the most common anomalies in people with down syndrome (ds) and have a significant impact on their daily life. |
2020-11-09 |
2023-08-13 |
Not clear |
| Beatriz C Freitas, Patricia C B Beltrão-Braga, Maria Carolina Marchett. Modeling Inflammation on Neurodevelopmental Disorders Using Pluripotent Stem Cells. Advances in neurobiology. vol 25. 2020-11-09. PMID:32578148. |
some of these genetic disorders are fragile x syndrome (fxs), rett syndrome (rtt), and down syndrome (ds). |
2020-11-09 |
2023-08-13 |
Not clear |
| Diletta Valentini, Antonella Mosca, Chiara Di Camillo, Annalisa Crudele, Maria Rita Sartorelli, Vittorio Scoppola, Luigi Tarani, Alberto Villani, Massimiliano Raponi, Antonio Novelli, Anna Alis. PNPLA3 gene polymorphism is associated with liver steatosis in children with Down syndrome. Nutrition, metabolism, and cardiovascular diseases : NMCD. vol 30. issue 9. 2020-11-09. PMID:32636123. |
we previously demonstrated that children with down syndrome (ds) exhibited a greater risk of steatosis than the general pediatric population. |
2020-11-09 |
2023-08-13 |
Not clear |
| Jacobo Limeres Posse, María Teresa Abeleira Pazos, María Fernández Casado, Mercedes Outumuro Rial, Pedro Diz Dios, Márcio Diniz-Freita. Safe zones of the maxillary alveolar bone in Down syndrome for orthodontic miniscrew placement assessed with cone-beam computed tomography. Scientific reports. vol 9. issue 1. 2020-11-04. PMID:31506517. |
the aim of this study was to quantify the available maxillary alveolar bone in a group of individuals with down syndrome (ds) to determine the best areas for orthodontic miniscrew placement. |
2020-11-04 |
2023-08-13 |
human |
| Yusuke Tsumura, Yuji Yamada, Tomoo Osumi, Motohiro Kato, Keita Terashima, Yoko Shioda, Chikako Kiyotani, Kimikazu Matsumoto, Daisuke Tomizaw. Successful Treatment With ATRA and Arsenic Trioxide for a Child With Down Syndrome and Acute Promyelocytic Leukemia. Journal of pediatric hematology/oncology. vol 42. issue 4. 2020-11-03. PMID:30807394. |
acute promyelocytic leukemia (apl) is rare in patients with down syndrome (ds). |
2020-11-03 |
2023-08-13 |
Not clear |
| Anouchka P Laurent, Rishi S Kotecha, Sébastien Maling. Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome. Leukemia. vol 34. issue 8. 2020-11-03. PMID:32433508. |
children with down syndrome (ds), who harbor constitutive trisomy 21, highlight the link between gain of chromosome 21 and leukemogenesis, with an increased risk of developing acute leukemia compared with other children. |
2020-11-03 |
2023-08-13 |
Not clear |
| Eli Van de Perck, Jolien Beyers, Marijke Dieltjens, Sara Op de Beeck, Johan Verbraecken, Paul Van de Heyning, An Boudewyns, Olivier M Vanderveke. Successful upper airway stimulation therapy in an adult Down syndrome patient with severe obstructive sleep apnea. Sleep & breathing = Schlaf & Atmung. vol 23. issue 3. 2020-11-02. PMID:30430373. |
the aim of this study was to report on the successful application of upper airway stimulation (uas) therapy in an adult down syndrome (ds) patient with severe obstructive sleep apnea (osa) and continuous positive airway pressure (cpap) intolerance. |
2020-11-02 |
2023-08-13 |
Not clear |
| Ni-Chung Lee, Wei-Chung Hsu, Lih-Maan Chang, Yi-Chen Chen, Po-Tsang Huang, Chun-Chin Chien, Yin-Hsiu Chien, Chi-Ling Chen, Wuh-Liang Hwu, Pei-Lin Le. REM sleep and sleep apnea are associated with language function in Down syndrome children: An analysis of a community sample. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 119. issue 1 Pt 3. 2020-11-02. PMID:31378642. |
the prevalence rate of obstructive sleep apnea (osa) in the community down syndrome (ds) children is not clear. |
2020-11-02 |
2023-08-13 |
Not clear |
| Nakisa Malakooti, Blaine Roberts, Melanie A Pritchard, Irene Volitakis, Ron C Kim, Ira T Lott, Catriona A McLean, David I Finkelstein, Paul A Adlar. Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology. Metallomics : integrated biometal science. vol 12. issue 1. 2020-11-02. PMID:31764918. |
down syndrome (ds) is a common intellectual disability, with an incidence of 1 in 700 and is caused by trisomy 21. |
2020-11-02 |
2023-08-13 |
Not clear |
| Georgina L Mortimer, Kathleen M Gillespi. Early Onset of Autoimmune Diabetes in Children with Down Syndrome-Two Separate Aetiologies or an Immune System Pre-Programmed for Autoimmunity? Current diabetes reports. vol 20. issue 9. 2020-11-02. PMID:32839884. |
an increased frequency of autoimmunity in children with down syndrome (ds) is well described but few studies have investigated the underlying mechanisms. |
2020-11-02 |
2023-08-13 |
Not clear |
| Simone Granno, Jonathon Nixon-Abell, Daniel C Berwick, Justin Tosh, George Heaton, Sultan Almudimeegh, Zenisha Nagda, Jean-Christophe Rain, Manuela Zanda, Vincent Plagnol, Victor L J Tybulewicz, Karen Cleverley, Frances K Wiseman, Elizabeth M C Fisher, Kirsten Harve. Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific reports. vol 9. issue 1. 2020-10-29. PMID:31086297. |
pathological mechanisms underlying down syndrome (ds)/trisomy 21, including dysregulation of essential signalling processes remain poorly understood. |
2020-10-29 |
2023-08-13 |
mouse |
| Sonali P Barwe, Ishnoor Sidhu, E Anders Kolb, Anilkumar Gopalakrishnapilla. Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology. Molecular therapy. Methods & clinical development. vol 19. 2020-10-29. PMID:33102613. |
approximately 1%-2% of children with down syndrome (ds) develop acute myeloid leukemia (aml) prior to age 5 years. |
2020-10-29 |
2023-08-13 |
Not clear |
| Pia Nerfeldt, Amalia Sundeli. Obstructive sleep apnea in children with down syndrome - Prevalence and evaluation of surgical treatment. International journal of pediatric otorhinolaryngology. vol 133. 2020-10-28. PMID:32126418. |
the prevalence of obstructive sleep apnea (osa) in the pediatric population with down syndrome (ds) is reported to be 45-76%. |
2020-10-28 |
2023-08-13 |
Not clear |
| Mabel Cristina Paiva Machado da Silva, Maria Carlla Aroucha Lyra, Híttalo Carlos Rodrigues de Almeida, Arnoldo Vasconcelos de Alencar Filho, Monica Vilela Heimer, Aronita Rosenblat. Caries experience in children and adolescents with Down Syndrome: A systematic review and meta-analysis. Archives of oral biology. vol 115. 2020-10-27. PMID:32422361. |
this study aimed to perform a systematic review and meta-analysis comparing the prevalence of dental caries in non-syndromic children with children and adolescents with down syndrome (ds). |
2020-10-27 |
2023-08-13 |
Not clear |
| Romina B Cejas, Jie Wang, Rachael Hageman-Blair, Song Liu, Javier G Blanc. Comparative genome-wide DNA methylation analysis in myocardial tissue from donors with and without Down syndrome. Gene. vol 764. 2020-10-27. PMID:32861879. |
down syndrome (ds, trisomy 21) is the most common major chromosomal aneuploidy compatible with life. |
2020-10-27 |
2023-08-13 |
human |
| Nicolas Richard, Nicole Beydon, Laura Berdah, Harriet Corvol, Guillaume Aubertin, Jessica Taytar. Nocturnal hypoventilation in Down syndrome children with or without sleep apnea. Pediatric pulmonology. vol 55. issue 5. 2020-10-23. PMID:32110849. |
there is a high prevalence of obstructive sleep apnea (osa) in children with down syndrome (ds), sometimes associated with alveolar hypoventilation. |
2020-10-23 |
2023-08-13 |
Not clear |