| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Suzuki, S Takashima, M Mizuguchi, M Kato, T Kunishita, T Tabir. High expression on Kunitz-type protease inhibitor-containing substances in the cerebral vessels of patients with Down syndrome. The Tohoku journal of experimental medicine. vol 174. issue 3. 1995-06-27. PMID:7761983. |
down syndrome (ds) brains, from 19 gestational weeks to 50 years of age were studied by immunohistochemical methods with a polyclonal antibody against synthetic peptide comprising part of the kunitz-type protease inhibitor (kpi) domain of alzheimer disease amyloid precursor protein (app), residues 301 to 323 of app 770. |
1995-06-27 |
2023-08-12 |
Not clear |
| K H Pitetti, S Bone. Cardiovascular fitness as related to leg strength in adults with mental retardation. Medicine and science in sports and exercise. vol 27. issue 3. 1995-06-22. PMID:7752871. |
the purpose of this study was to compare cardiovascular fitness to leg strength of young adults (mean age = 25.2 yr) with mental retardation (mr) with and without down syndrome (ds) and to determine whether a relationship exists. |
1995-06-22 |
2023-08-12 |
human |
| H Avet-Loiseau, F Mechinaud, J L Haroussea. Clonal hematologic disorders in Down syndrome. A review. Journal of pediatric hematology/oncology. vol 17. issue 1. 1995-06-13. PMID:7743232. |
children with down syndrome (ds) carry an elevated risk of developing clonal hematologic disorders. |
1995-06-13 |
2023-08-12 |
Not clear |
| J J Shen, B J Williams, A Zipursky, J Doyle, S L Sherman, P A Jacobs, A L Shugar, S W Soukup, T J Hassol. Cytogenetic and molecular studies of Down syndrome individuals with leukemia. American journal of human genetics. vol 56. issue 4. 1995-05-15. PMID:7717402. |
there is an increased risk of leukemia in down syndrome (ds) patients, with estimates ranging from 14 to 30 times the incidence rate observed for chromosomally normal children. |
1995-05-15 |
2023-08-12 |
Not clear |
| C A Lemere, J S Munger, G P Shi, L Natkin, C Haass, H A Chapman, D J Selko. The lysosomal cysteine protease, cathepsin S, is increased in Alzheimer's disease and Down syndrome brain. An immunocytochemical study. The American journal of pathology. vol 146. issue 4. 1995-05-12. PMID:7717452. |
in this study, we examined the presence and localization of cat s by immunocytochemistry in 21 control, 24 alzheimer's disease (ad), and 10 down syndrome (ds) postmortem brains. |
1995-05-12 |
2023-08-12 |
human |
| C Stoll, Y Alembik, B Dott, M P Rot. Recent trends in the prevalence of Down syndrome in north-eastern France. Annales de genetique. vol 37. issue 4. 1995-05-10. PMID:7710252. |
examination of data from our regional registry of congenital anomalies indicated that 217 children with down syndrome (ds) were registered (liveborn, stillborn or termination of pregnancy) to mothers living in the strasbourg area from 1980 to 1992 inclusive. |
1995-05-10 |
2023-08-12 |
Not clear |
| S A Tan, H H Cheng, G S Ye. Birth defects--the state of awareness amongst mothers. Singapore medical journal. vol 35. issue 5. 1995-05-02. PMID:7701364. |
only 20% to 25% of mothers were aware of the actual incidence of birth defects, and only 2.5%-10% knew that the risk of down syndrome (ds) increases with maternal age. |
1995-05-02 |
2023-08-12 |
Not clear |
| J P Das, R K Mishr. Assessment of cognitive decline associated with aging: a comparison of individuals with Down syndrome and other etiologies. Research in developmental disabilities. vol 16. issue 1. 1995-04-28. PMID:7701089. |
cognitive processes and their decline with aging were studied in individuals with down syndrome (ds) and individuals of comparable mental handicap without down syndrome (nonds). |
1995-04-28 |
2023-08-12 |
Not clear |
| K K Sanford, R Parshad, F M Price, R E Tarone, A R Lehman. G2 phase repair of X-ray-induced chromosomal DNA damage in trichothiodystrophy cells. Mutation research. vol 346. issue 2. 1995-04-11. PMID:7885400. |
these responses are compared with those of five lines from clinically normal controls, lines from xeroderma pigmentosum (xp), cockayne syndrome (cs), down syndrome (ds), and ataxia telangiectasia (at) patients. |
1995-04-11 |
2023-08-12 |
Not clear |
| B Brambati, L Tului, I Bonacchi, K Shrimanker, Y Suzuki, J G Grudzinska. Serum PAPP-A and free beta-hCG are first-trimester screening markers for Down syndrome. Prenatal diagnosis. vol 14. issue 11. 1995-04-06. PMID:7533285. |
serum measurements of pregnancy-associated plasma protein a (papp-a) and the free beta-human chorionic gonadotrophin (hcg) subunit were made in 13 women with down syndrome (ds) pregnancies and six other women with fetal aneuploidy ascertained at chorionic villus sampling (cvs), as well as 89 women with contemporaneous normal control pregnancies. |
1995-04-06 |
2023-08-12 |
Not clear |
| P Johannsen, J Ma. [Alzheimer-type dementia and Down syndrome]. Ugeskrift for laeger. vol 157. issue 8. 1995-04-03. PMID:7879299. |
dementia is seen earlier and more often in patients with down syndrome (ds) than in the general population. |
1995-04-03 |
2023-08-12 |
Not clear |
| A Peterson, N Patil, C Robbins, L Wang, D R Cox, R M Myer. A transcript map of the Down syndrome critical region on chromosome 21. Human molecular genetics. vol 3. issue 10. 1995-03-16. PMID:7849696. |
a catalogue of the genes encoded by chromosome 21 would provide a framework for assigning roles in the etiology of down syndrome (ds) to individual genes. |
1995-03-16 |
2023-08-12 |
Not clear |
| N Patil, A Peterson, A Rothman, P J de Jong, R M Myers, D R Co. A high resolution physical map of 2.5 Mbp of the Down syndrome region on chromosome 21. Human molecular genetics. vol 3. issue 10. 1995-03-16. PMID:7849705. |
the region surrounding d21s55 in band 21q22 of human chromosome 21 has been implicated in the etiology of down syndrome (ds). |
1995-03-16 |
2023-08-12 |
human |
| V P Prasher, L Robinson, V H Krishnan, M C Chun. Podiatric disorders among children with Down syndrome and learning disability. Developmental medicine and child neurology. vol 37. issue 2. 1995-03-16. PMID:7851669. |
this study investigated podiatric pathology in seven- to 14-year-old children with down syndrome (ds) and non-down syndrome learning-disabled and non-learning-disabled age-matched controls. |
1995-03-16 |
2023-08-12 |
Not clear |
| M L Lacey-Casem, M L Oster-Granit. The neuropathology of the trisomy 16 mouse. Critical reviews in neurobiology. vol 8. issue 4. 1995-03-14. PMID:7850875. |
the purpose of this review is to describe the neuropathology of mouse trisomy 16 and to compare that pathology with the pathologic features observed in individuals with down syndrome (ds) trisomy 21 (ts21). |
1995-03-14 |
2023-08-12 |
mouse |
| M de Braekeleer, T Landry, A Cholett. Consanguinity and kinship in Down syndrome in Saguenay Lac-Saint-Jean (Québec). Annales de genetique. vol 37. issue 2. 1994-12-30. PMID:7985984. |
genealogies of 67 cases of down syndrome (ds) cytogenetically proven as trisomy 21 born in saguenay-lac-saint-jean were reconstructed using a population register. |
1994-12-30 |
2023-08-12 |
Not clear |
| A Luke, N J Roizen, M Sutton, D A Schoelle. Energy expenditure in children with Down syndrome: correcting metabolic rate for movement. The Journal of pediatrics. vol 125. issue 5 Pt 1. 1994-12-13. PMID:7965444. |
children with down syndrome (ds) have a high prevalence of obesity. |
1994-12-13 |
2023-08-12 |
human |
| R Biagiotti, E Periti, E Cariat. Humerus and femur length in fetuses with Down syndrome. Prenatal diagnosis. vol 14. issue 6. 1994-11-10. PMID:7937578. |
the aim of the study was to assess the value of sonographic measurement of fetal humerus and femur lengths in the second trimester as a screening tool for down syndrome (ds). |
1994-11-10 |
2023-08-12 |
Not clear |
| K Gyves-Ray, S Kirchner, S Stein, R Heller, M Hernanz-Schulma. Cystic lung disease in Down syndrome. Pediatric radiology. vol 24. issue 2. 1994-10-05. PMID:8078717. |
it is well known that down syndrome (ds) affects multiple organ systems, including cardiovascular, gastrointestinal, hematological, and musculoskeletal. |
1994-10-05 |
2023-08-12 |
Not clear |
| . Down syndrome prevalence at birth--United States, 1983-1990. MMWR. Morbidity and mortality weekly report. vol 43. issue 33. 1994-09-22. PMID:8065293. |
down syndrome* (ds) (trisomy 21) is one of the most serious and frequently reported birth defects among live-born infants and an important cause of mental retardation. |
1994-09-22 |
2023-08-12 |
Not clear |