| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Wegiel, H M Wisniewski, I Kuchna, M Tarnawski, E Badmajew, E Popovitch, J Kulczycki, W K Dowjat, T Wisniewsk. Cell-type-specific enhancement of amyloid-beta deposition in a novel presenilin-1 mutation (P117L). Journal of neuropathology and experimental neurology. vol 57. issue 9. 1998-09-25. PMID:9737546. |
the neuropathology of 2 subjects with this ps1 mutation (ages at death: 35 and 37 years) was compared to four down syndrome (ds) patients (mean age at death: 62 years) and 4 sporadic ad patients (mean age at death: 79 years with a mean duration of disease of 18 years). |
1998-09-25 |
2023-08-12 |
human |
| D Satgé, D Sommelet, A Geneix, M Nishi, P Malet, M Vekeman. A tumor profile in Down syndrome. American journal of medical genetics. vol 78. issue 3. 1998-09-23. PMID:9677053. |
we conducted a review of cancers in down syndrome (ds), because solid tumors are poorly understood in ds. |
1998-09-23 |
2023-08-12 |
human |
| b' A C Dumaret, C De Vigan, C Julian-Reynier, J Goujard, D Rosset, S Aym\\xc3\\xa. Adoption and fostering of babies with Down syndrome: a cohort of 593 cases. Prenatal diagnosis. vol 18. issue 5. 1998-08-28. PMID:9621377.' |
recently, professionals in france have noticed an increase in newborns with down syndrome (ds) being placed for adoption. |
1998-08-28 |
2023-08-12 |
Not clear |
| R Zanini, M Tarantini, V Cerri, C Jacobello, D Bellotti, S Lancetti, S Scalchi, C Groli, U A Bianch. 'Dual positivity' for neural tube defects and down syndrome at maternal serum screening: gestational outcome. Fetal diagnosis and therapy. vol 13. issue 2. 1998-08-28. PMID:9650657. |
to evaluate the gestational outcome of pregnancies screen-positive for both neural tube defects (ntd) and down syndrome (ds) ('dual positivity'). |
1998-08-28 |
2023-08-12 |
Not clear |
| L B Bazzett, Y Yaron, J E O'Brien, G Critchfield, R L Kramer, M Ayoub, M P Johnson, M I Evan. Fetal gender impact on multiple-marker screening results. American journal of medical genetics. vol 76. issue 5. 1998-08-11. PMID:9556293. |
maternal serum alpha-fetoprotein (msafp), human chorionic gonadotropin (hcg), and unconjugated estriol (ue3) are used in combination with maternal age to calculate the risk for down syndrome (ds) in pregnancy. |
1998-08-11 |
2023-08-12 |
human |
| J Hon, F A Huppert, A J Holland, P Watso. The value of the Rivermead Behavioural Memory Test (Children's Version) in an epidemiological study of older adults with Down syndrome. The British journal of clinical psychology. vol 37. issue 1. 1998-07-13. PMID:9547957. |
the rivermead behavioural memory test for children (rbmt-c) was used to assess a population-based sample of 74 people with down syndrome (ds) aged 30 years and over (range 30-65 years) living in the cambridge health district. |
1998-07-13 |
2023-08-12 |
human |
| G D Pearlson, S N Breiter, E H Aylward, A C Warren, M Grygorcewicz, S Frangou, P E Barta, M B Pulsife. MRI brain changes in subjects with Down syndrome with and without dementia. Developmental medicine and child neurology. vol 40. issue 5. 1998-07-07. PMID:9630260. |
individuals with down syndrome (ds), a disorder of known genetic etiology (trisomy of chromosome 21), exhibit several types of structural brain abnormalities that are detectable pathologically and by mri. |
1998-07-07 |
2023-08-12 |
human |
| R Caraballo, R Cersósimo, H Arroyo, N Fejerma. [Symptomatic West's syndrome: specific etiological link to unexpected response to treatment]. Revista de neurologia. vol 26. issue 151. 1998-07-02. PMID:9585945. |
however new evidences arose in the last few years showing that particular association of ws with down syndrome (ds), type 1 neurofibromatosis (nf1) and cerebral palsy (cp) with periventricular leukomalacia (pl) tend to behave as cryptogenic or idiopathic cases showing control of infantile spasms (is) and disappearance of hypsarrhythmia after treatment. |
1998-07-02 |
2023-08-12 |
Not clear |
| C Stoll, Y Alembik, B Dott, M P Rot. Study of Down syndrome in 238,942 consecutive births. Annales de genetique. vol 41. issue 1. 1998-06-25. PMID:9599651. |
the genetics and the epidemiology of down syndrome (ds) was studied in the area which is covered by our registry of congenital malformations. |
1998-06-25 |
2023-08-12 |
Not clear |
| G E Demas, R J Nelson, B K Krueger, P J Yarowsk. Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice. Behavioural brain research. vol 90. issue 2. 1998-05-27. PMID:9521551. |
to evaluate the cognitive phenotype of the segmental trisomy 16 (ts65dn) mouse, a model of down syndrome (ds, trisomy 21), we assessed spatial working and reference memory using a 12-arm radial maze (ram). |
1998-05-27 |
2023-08-12 |
mouse |
| J B Leverenz, M A Raskin. Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis. Experimental neurology. vol 150. issue 2. 1998-05-22. PMID:9527899. |
the presence of the neuropathological alterations of alzheimer's disease (ad) in essentially all older down syndrome (ds) patients suggests that the examination of younger ds patients may clarify the early pathological progression of ad. |
1998-05-22 |
2023-08-12 |
Not clear |
| N Schupf, D Kapell, B Nightingale, A Rodriguez, B Tycko, R Mayeu. Earlier onset of Alzheimer's disease in men with Down syndrome. Neurology. vol 50. issue 4. 1998-05-07. PMID:9566384. |
virtually all individuals with down syndrome (ds) have neuropathologic changes characteristic of alzheimer's disease (ad) beginning at 40 years of age. |
1998-05-07 |
2023-08-12 |
Not clear |
| P D Mehta, A J Dalton, S P Mehta, K S Kim, E A Sersen, H M Wisniewsk. Increased plasma amyloid beta protein 1-42 levels in Down syndrome. Neuroscience letters. vol 241. issue 1. 1998-04-28. PMID:9502204. |
amyloid beta protein 1-40 (a beta40) and a beta42 levels were quantitated in plasma from 43 persons with down syndrome (ds; 26-68 years of age), 43 age-matched normal controls, and 19 non-ds mentally retarded (mr) persons (26-91 years of age) by using a sandwich enzyme linked immunosorbent assay. |
1998-04-28 |
2023-08-12 |
Not clear |
| A Egeo, M Mazzocco, F Sotgia, P Arrigo, R Oliva, S Bergonòn, D Nizetic, A Rasore-Quartino, P Scartezzin. Identification and characterization of a new human cDNA from chromosome 21q22.3 encoding a basic nuclear protein. Human genetics. vol 102. issue 3. 1998-04-24. PMID:9544840. |
congenital heart disease (chd) affects over 40% of down syndrome (ds) patients. |
1998-04-24 |
2023-08-12 |
human |
| M Ohira, N Seki, T Nagase, K Ishikawa, N Nomura, O Ohar. Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1. Genomics. vol 47. issue 2. 1998-04-15. PMID:9479503. |
clinical interest in the genes on human chromosome 21, especially with respect to down syndrome (ds), has provided a strong impetus for the creation of a transcript map of this chromosome. |
1998-04-15 |
2023-08-12 |
mouse |
| M Beeghly, D Cicchett. Talking about self and other: emergence of an internal state lexicon in young children with Down syndrome. Development and psychopathology. vol 9. issue 4. 1998-03-24. PMID:9449003. |
this study examined the emergence of an is lexicon in a cross-sectional sample of young children with down syndrome (ds) and a cognitively and demographically comparable group of normally developing (nd) children. |
1998-03-24 |
2023-08-12 |
Not clear |
| R L Kramer, Y Yaron, J E O'Brien, G Critchfield, M Ayoub, M P Johnson, C R Qualls, M I Evan. Effect of adjustment of maternal serum alpha-fetoprotein levels in insulin-dependent diabetes mellitus. American journal of medical genetics. vol 75. issue 2. 1998-03-24. PMID:9450880. |
our objective was to determine the effect of the 20% upward adjustment of maternal serum alphafetoprotein (msafp) in patients with insulin-dependent diabetes mellitus (iddm) on the number of patients that would be classified at increased risk for pregnancy complicated by either down syndrome (ds) or neural tube defect (ntd). |
1998-03-24 |
2023-08-12 |
Not clear |
| K Yamakawa, Y K Huot, M A Haendelt, R Hubert, X N Chen, G E Lyons, J R Korenber. DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Human molecular genetics. vol 7. issue 2. 1998-03-17. PMID:9426258. |
down syndrome (ds), a major cause of mental retardation, is characterized by subtle abnormalities of cortical neuroanatomy, neurochemistry and function. |
1998-03-17 |
2023-08-12 |
mouse |
| M Megías, R Verduga, M Dierssen, J Flórez, R Insausti, D Cresp. Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice. Neuroreport. vol 8. issue 16. 1998-02-26. PMID:9427310. |
ts65dn mice were developed as a model of down syndrome (ds); they are trisomic for the distal segment of chromosome 16 (mmu16), which contains genes syntenic with some of the genes located on the critical region of human chromosome 21 (hsa21). |
1998-02-26 |
2023-08-12 |
mouse |
| D Satgé, A J Sasco, N L Carlsen, C A Stiller, H Rubie, B Hero, B de Bernardi, J de Kraker, C Coze, P Kogner, F Langmark, F G Hakvoort-Cammel, D Beck, N von der Weid, S Parkes, O Hartmann, R J Lippens, W A Kamps, D Sommele. A lack of neuroblastoma in Down syndrome: a study from 11 European countries. Cancer research. vol 58. issue 3. 1998-02-24. PMID:9458088. |
an epidemiological investigation in 11 european countries comprising a total childhood population of 54.1 million children and using 8 separate data sources was conducted to evaluate the occurrence of neuroblastoma in down syndrome (ds). |
1998-02-24 |
2023-08-12 |
human |