| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J E O'Brien, E Dvorin, Y Yaron, M Ayoub, M P Johnson, R F Hume, M I Evan. Differential increases in AFP, hCG, and uE3 in twin pregnancies: impact on attempts to quantify Down syndrome screening calculations. American journal of medical genetics. vol 73. issue 2. 1998-02-12. PMID:9409857. |
since the advent of multiple marker screening (mms) for down syndrome (ds) risk calculations, limitations for twins have been apparent. |
1998-02-12 |
2023-08-12 |
Not clear |
| B J Lange, N Kobrinsky, D R Barnard, D C Arthur, J D Buckley, W B Howells, S Gold, J Sanders, S Neudorf, F O Smith, W G Wood. Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891. Blood. vol 91. issue 2. 1998-02-11. PMID:9427716. |
in recent pediatric trials of acute myeloid leukemia (aml), children with down syndrome (ds) have had significantly more megakaryoblastic leukemia and have experienced better outcome than other children. |
1998-02-11 |
2023-08-12 |
Not clear |
| C P Torfs, L H Honoré, C J Curr. Is there an association of Down syndrome and omphalocele? American journal of medical genetics. vol 73. issue 4. 1998-02-02. PMID:9415464. |
the possible association of down syndrome (ds) with omphalocele is controversial. |
1998-02-02 |
2023-08-12 |
Not clear |
| R Seidl, S Greber, E Schuller, G Bernert, N Cairns, G Lube. Evidence against increased oxidative DNA-damage in Down syndrome. Neuroscience letters. vol 235. issue 3. 1998-01-29. PMID:9406888. |
in down syndrome (ds), oxidative dna-damage may play a role in the pathogenesis of characteristic mental retardation and precocious dementia of alzheimer type. |
1998-01-29 |
2023-08-12 |
Not clear |
| J Piven, P Palme. Cognitive deficits in parents from multiple-incidence autism families. Journal of child psychology and psychiatry, and allied disciplines. vol 38. issue 8. 1998-01-29. PMID:9413799. |
this study compares parents of two autistic children with parents of a down syndrome (ds) proband, on tests of intelligence, reading and spelling, and executive function. |
1998-01-29 |
2023-08-12 |
Not clear |
| S W Beasley, M Allen, N Myer. The effects of Down syndrome and other chromosomal abnormalities on survival and management in oesophageal atresia. Pediatric surgery international. vol 12. issue 8. 1998-01-22. PMID:9354723. |
in down syndrome (ds) 50% will have pure oa with no tracheo-oesophageal fistula. |
1998-01-22 |
2023-08-12 |
Not clear |
| E P Tardy, A Tóth, G Kosztolány. Prenatal exclusion of segmental trisomy in familial chromosome 21 pericentric inversion by fluorescence in situ hybridization. Prenatal diagnosis. vol 17. issue 9. 1998-01-02. PMID:9316133. |
after determining the structural rearrangement in the mother and her affected son with 46,xy,rec(21)dup(21q)inv(21)(p11q22) resulting in down syndrome (ds), a chorionic villus sample from the current pregnancy was analysed for the copy number of the ds critical region with a cosmid contig. |
1998-01-02 |
2023-08-12 |
Not clear |
| D S Woodruff-Pak, M Papk. Huntington's disease and eyeblink classical conditioning: normal learning but abnormal timing. Journal of the International Neuropsychological Society : JINS. vol 2. issue 4. 1997-12-29. PMID:9375181. |
comparisons of hd patients to patients with other neurodegenerative diseases (probable alzheimer's disease (pad) and down syndrome (ds) over the age of 35 with presumed alzheimer-like neuropathology) and to patients with cerebellar lesions demonstrated significantly better ebcc performance in hd. |
1997-12-29 |
2023-08-12 |
human |
| D S Geldmacher, A J Lerner, J M Voci, E A Noelker, L C Somple, P J Whitehous. Treatment of functional decline in adults with Down syndrome using selective serotonin-reuptake inhibitor drugs. Journal of geriatric psychiatry and neurology. vol 10. issue 3. 1997-12-23. PMID:9322131. |
alzheimer's disease (ad) is a common cause of functional decline in down syndrome (ds) adults. |
1997-12-23 |
2023-08-12 |
Not clear |
| R Ankathil, P Kusumakumary, M K Nai. Increased levels of mutagen-induced chromosome breakage in Down syndrome children with malignancy. Cancer genetics and cytogenetics. vol 99. issue 2. 1997-12-23. PMID:9398867. |
even though an association between down syndrome (ds) and malignancies has been established, the mechanism behind this is still unclear. |
1997-12-23 |
2023-08-12 |
Not clear |
| H M Kempski, J M Chessells, B R Reeve. Deletions of chromosome 21 restricted to the leukemic cells of children with Down syndrome and leukemia. Leukemia. vol 11. issue 11. 1997-12-09. PMID:9369434. |
down syndrome (ds) is associated with an increased risk of developing hematological malignancies, but the basis for this predisposition is so far unknown. |
1997-12-09 |
2023-08-12 |
Not clear |
| N R Dasgupta, R M Pauli, V K Horton, C A Reise. Validation of radiographic criteria for the diagnosis of Down syndrome in stillborn infants. American journal of medical genetics. vol 72. issue 3. 1997-11-25. PMID:9332668. |
we assessed the utility of radiographic findings as aids to the diagnosis of down syndrome (ds) in stillborn infants. |
1997-11-25 |
2023-08-12 |
Not clear |
| C P Monteiro, A Varela, M Pinto, J Neves, G M Felisberto, C Vaz, M P Bicho, M J Laire. Effect of an aerobic training on magnesium, trace elements and antioxidant systems in a Down syndrome population. Magnesium research. vol 10. issue 1. 1997-11-25. PMID:9339840. |
the aim of the present study was to determine the effect of an aerobic training on plasma and red blood cells' levels of magnesium, copper, selenium and zinc and on some oxidative stress parameters in a down syndrome (ds) sample population. |
1997-11-25 |
2023-08-12 |
human |
| J Guimera, C Pucharcós, A Domènech, C Casas, A Solans, T Gallardo, J Ashley, M Lovett, X Estivill, M Pritchar. Cosmid contig and transcriptional map of three regions of human chromosome 21q22: identification of 37 novel transcripts by direct selection. Genomics. vol 45. issue 1. 1997-11-20. PMID:9339361. |
human chromosome 21 is associated with many disorders, including down syndrome (ds). |
1997-11-20 |
2023-08-12 |
human |
| J Guimera, C Pucharcós, A Domènech, C Casas, A Solans, T Gallardo, J Ashley, M Lovett, X Estivill, M Pritchar. Cosmid contig and transcriptional map of three regions of human chromosome 21q22: identification of 37 novel transcripts by direct selection. Genomics. vol 45. issue 1. 1997-11-20. PMID:9339361. |
in an effort to identify genes involved in brain development or function and therefore implicated in the mental retardation associated with ds, we chose yacs from three regions of chromosome 21: a region within the so-called "down syndrome critical region," a region proximal to it, and one distal to it. |
1997-11-20 |
2023-08-12 |
human |
| S A Ivarsson, U B Ericsson, J Gustafsson, M Forslund, P Vegfors, G Anneré. The impact of thyroid autoimmunity in children and adolescents with Down syndrome. Acta paediatrica (Oslo, Norway : 1992). vol 86. issue 10. 1997-11-19. PMID:9350885. |
the extent to which autoimmunity contributes to thyroid dysfunction in individuals with down syndrome (ds) has not been clarified. |
1997-11-19 |
2023-08-12 |
Not clear |
| A M Stolwijk, P H Jongbloet, G A Zielhuis, F J Gabreël. Seasonal variation in the prevalence of Down syndrome at birth: a review. Journal of epidemiology and community health. vol 51. issue 4. 1997-10-29. PMID:9328537. |
many studies on seasonality in down syndrome (ds) have been performed and have come to different conclusions. |
1997-10-29 |
2023-08-12 |
Not clear |
| R Seidl, E Schuller, N Cairns, G Lube. Evidence against increased glycoxidation in patients with Alzheimer's disease. Neuroscience letters. vol 232. issue 1. 1997-10-23. PMID:9292889. |
increased levels of oxidized products from non-enzymatic glycation could be found in brains of patients with ad and of aged down syndrome (ds) subjects with abundant ad-like neuropathological lesions. |
1997-10-23 |
2023-08-12 |
human |
| A L Christianso. Down syndrome in black South African infants and children--clinical features and delayed diagnosis. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. vol 87. issue 8. 1997-10-23. PMID:9323405. |
down syndrome (ds), the commonest cause of congenital developmental disability in developed countries, has only recently been shown to have an incidence in black south african neonates as high, and in some studies higher, than currently seen in first-world nations. |
1997-10-23 |
2023-08-12 |
Not clear |
| A Antonucci, A Di Baldassarre, F Di Giacomo, L Stuppia, G Palk. Detection of apoptosis in peripheral blood cells of 31 subjects affected by Down syndrome before and after zinc therapy. Ultrastructural pathology. vol 21. issue 5. 1997-10-14. PMID:9273975. |
thirty-one patients affected by down syndrome (ds) were investigated to study the presence of apoptosis in peripheral blood cells in relation to the plasma levels of zinc. |
1997-10-14 |
2023-08-12 |
human |