| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bing Feng, William Hoskins, Yan Zhang, Zibo Meng, David C Samuels, Jiandong Wang, Ruofan Xia, Chao Liu, Jijun Tang, Yan Gu. Bi-stream CNN Down Syndrome screening model based on genotyping array. BMC medical genomics. vol 11. issue Suppl 5. 2019-05-29. PMID:30453947. |
human down syndrome (ds) is usually caused by genomic micro-duplications and dosage imbalances of human chromosome 21. |
2019-05-29 |
2023-08-13 |
human |
| Hadri Hadi Yusof, Han-Chung Lee, Eryse Amira Seth, Xiangzhong Wu, Chelsee A Hewitt, Hamish S Scott, Pike-See Cheah, Yue-Ming Li, De-Ming Chau, King-Hwa Lin. Expression Profiling of Notch Signalling Pathway and Gamma-Secretase Activity in the Brain of Ts1Cje Mouse Model of Down Syndrome. Journal of molecular neuroscience : MN. vol 67. issue 4. 2019-05-29. PMID:30758748. |
down syndrome (ds) individuals exhibit an increased number of glial cells (particularly astrocytes), and reduced number of neurons suggesting the involvement of notch signalling pathway in the neurogenic-to-gliogenic shift in ds brain. |
2019-05-29 |
2023-08-13 |
mouse |
| Simone Bagattoni, Giovanni D'Alessandro, Maria Rosaria Gatto, Gabriela Pian. Applicability of Demirjian's method for age estimation in a sample of Italian children with Down syndrome: A case-control retrospective study. Forensic science international. vol 298. 2019-05-29. PMID:30927720. |
the aims of this study were to evaluate the applicability of the demirjian method in a sample of italian children with down syndrome (ds) and to compare the data with age and gender matched healthy subjects (non-ds). |
2019-05-29 |
2023-08-13 |
human |
| Elizabeth A Will, Kelly E Caravella, Laura J Hahn, Deborah J Fidler, Jane E Robert. Adaptive behavior in infants and toddlers with Down syndrome and fragile X syndrome. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 177. issue 3. 2019-05-28. PMID:29399949. |
individuals with down syndrome (ds) experience deficits across all domains of adaptive functioning, however little is known about the emergence and age-related changes of these impairments compared to other neurogenetic disorders with similar intellectual disability impairments, such as fragile x syndrome (fxs). |
2019-05-28 |
2023-08-13 |
human |
| Pankaj D Mehta, Bruce A Patrick, Marc Barshatzky, Sangita P Mehta, Janusz Frackowiak, Bozena Mazur-Kolecka, Jerzy Wegiel, Thomas Wisniewski, David L Mille. Generation and Partial Characterization of Rabbit Monoclonal Antibody to Pyroglutamate Amyloid-β3-42 (pE3-Aβ). Journal of Alzheimer's disease : JAD. vol 62. issue 4. 2019-05-28. PMID:29504532. |
n-terminally truncated pyroglutamate amyloid-β (aβ) peptide starting at position 3 represents a significant fraction of aβ peptides (pe3-aβ) in amyloid plaques of postmortem brains from patients with alzheimer's disease (ad) and older persons with down syndrome (ds). |
2019-05-28 |
2023-08-13 |
mouse |
| Sandra Guidi, Andrea Giacomini, Fiorenza Stagni, Marco Emili, Beatrice Uguagliati, Maria Paola Bonasoni, Renata Bartesagh. Abnormal development of the inferior temporal region in fetuses with Down syndrome. Brain pathology (Zurich, Switzerland). vol 28. issue 6. 2019-05-28. PMID:29509279. |
down syndrome (ds) is a genetic condition associated with impairment in several cognitive domains. |
2019-05-28 |
2023-08-13 |
Not clear |
| Şeyda Özçalışkan, Lauren B Adamson, Nevena Dimitrova, Stephanie Bauman. Do Parents Model Gestures Differently When Children's Gestures Differ? Journal of autism and developmental disorders. vol 48. issue 5. 2019-05-27. PMID:29177617. |
children with autism spectrum disorder (asd) or with down syndrome (ds) show diagnosis-specific differences from typically developing (td) children in gesture production. |
2019-05-27 |
2023-08-13 |
Not clear |
| Matthew A Cody Davis, Amy Spriggs, Alexis Rodgers, Jonathan Campbel. The Effects of a Peer-Delivered Social Skills Intervention for Adults with Comorbid Down Syndrome and Autism Spectrum Disorder. Journal of autism and developmental disorders. vol 48. issue 6. 2019-05-27. PMID:29274009. |
deficits in social skills are often exhibited in individuals with comorbid down syndrome (ds) and autism spectrum disorder (asd), and there is a paucity of research to help guide intervention for this population. |
2019-05-27 |
2023-08-13 |
human |
| M Colella, C Stilo, A Cocchella, D Bianchini, A Pilotto, P Del Sette, R Musolin. Cerebral vasoreactivity and intima-media thickness in Down syndrome: A case-control study. Journal of the neurological sciences. vol 385. 2019-05-24. PMID:29406914. |
subjects with down syndrome (ds) have high prevalence of cerebral vascular amyloidosis, cognitive decline and dementia. |
2019-05-24 |
2023-08-13 |
human |
| Theodora J Matthews, Dawn C Allain, Anne L Matthews, Anna Mitchell, Stephanie L Santoro, Leslie Cohe. An assessment of health, social, communication, and daily living skills of adults with Down syndrome. American journal of medical genetics. Part A. vol 176. issue 6. 2019-05-21. PMID:29696786. |
adults with down syndrome (ds) are surviving longer, yet data delineating life skills are lacking. |
2019-05-21 |
2023-08-13 |
human |
| Julia Vonasek, Peter Asdahl, Mats Heyman, Karin Källén, Henrik Hasl. Late mortality and morbidity among long-term leukemia survivors with Down syndrome: A nationwide population-based cohort study. Pediatric blood & cancer. vol 65. issue 9. 2019-05-20. PMID:29797653. |
although individuals with down syndrome (ds) have a substantially increased risk of leukemia, information on late effects in this group is almost nonexistent. |
2019-05-20 |
2023-08-13 |
Not clear |
| Yuka Iwaya, Jun Muneuchi, Yuka Inoue, Mamie Watanabe, Seigo Okada, Yoshie Ochia. Relationship Between Pulmonary Arterial Resistance and Compliance in Patients with Down Syndrome. Pediatric cardiology. vol 40. issue 4. 2019-05-17. PMID:30830280. |
this study aimed to clarify the characteristics of pulmonary arterial resistance (rp)-compliance (cp) coupling in individuals with down syndrome (ds), who have increased risks of pulmonary arterial hypertension (pah). |
2019-05-17 |
2023-08-13 |
Not clear |
| Andrea A Beckhaus, Jose A Castro-Rodrigue. Down Syndrome and the Risk of Severe RSV Infection: A Meta-analysis. Pediatrics. vol 142. issue 3. 2019-05-15. PMID:30093540. |
down syndrome (ds) is the most common chromosomal condition in live-born infants worldwide, and lower respiratory infection caused by respiratory syncytial virus (rsv) is a leading cause of hospital admissions. |
2019-05-15 |
2023-08-13 |
Not clear |
| Ewa Parfieniuk, Paulina Samczuk, Tomasz Kowalczyk, Karolina Pietrowska, Magdalena Niemira, Magdalena Paczkowska-Abdulsalam, Slawomir Wolczynski, Adam Kretowski, Michal Ciborowski, Monika Zbucka-Kretowsk. Maternal plasma metabolic fingerprint indicative for fetal Down syndrome. Prenatal diagnosis. vol 38. issue 11. 2019-05-15. PMID:30094843. |
the objective of the study was to perform maternal plasma metabolic fingerprinting to evaluate differences in plasma metabolites between healthy and down syndrome (ds) pregnancies and to indicate novel non-invasive markers for ds prenatal diagnostics. |
2019-05-15 |
2023-08-13 |
Not clear |
| Jonathan D Santoro, Sarah Lee, Michael Mlynash, Thuy Nguyen, Daniel V Lazzareschi, Lironn D Kraler, Elizabeth W Mayne, Gary K Steinber. Blood Pressure Elevation and Risk of Moyamoya Syndrome in Patients With Trisomy 21. Pediatrics. vol 142. issue 4. 2019-05-15. PMID:30190347. |
individuals with down syndrome (ds) are at risk for the development of moyamoya syndrome (mms); mms is often recognized only after a resulting stroke has occurred. |
2019-05-15 |
2023-08-13 |
Not clear |
| Uma H Athale, Maneka Puligandla, Kristen E Stevenson, Barbara Asselin, Luis A Clavell, Peter D Cole, Kara M Kelly, Caroline Laverdiere, Jean-Marie Leclerc, Bruno Michon, Marshall A Schorin, Maria Luisa Sulis, Jennifer J G Welch, Marian H Harris, Donna S Neuberg, Stephen E Sallan, Lewis B Silverma. Outcome of children and adolescents with Down syndrome treated on Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium protocols 00-001 and 05-001. Pediatric blood & cancer. vol 65. issue 10. 2019-05-10. PMID:29878490. |
children and adolescents with down syndrome (ds) and acute lymphoblastic leukemia (all) are reported to have increased relapse rates and therapy-related mortality (trm). |
2019-05-10 |
2023-08-13 |
Not clear |
| Christine de Weger, Nienke Boonstra, Jeroen Goossen. Effects of bifocals on visual acuity in children with Down syndrome: a randomized controlled trial. Acta ophthalmologica. vol 97. issue 4. 2019-05-10. PMID:30367541. |
children with down syndrome (ds) typically have reduced visual acuity (va) and accommodation lag, but it is unclear whether prescribed glasses should correct both distance va (dva) and near va (nva) due to the lack of rcts. |
2019-05-10 |
2023-08-13 |
Not clear |
| Daniela Valenti, Lidia de Bari, Domenico de Rasmo, Anna Signorile, Alexandra Henrion-Caude, Andrea Contestabile, Rosa Anna Vacc. The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model. Biochimica et biophysica acta. vol 1862. issue 6. 2019-05-08. PMID:26964795. |
mitochondrial dysfunctions critically impair nervous system development and are potentially involved in the pathogenesis of various neurodevelopmental disorders, including down syndrome (ds), the most common genetic cause of intellectual disability. |
2019-05-08 |
2023-08-13 |
mouse |
| Jessica Fredericksen, Vanessa Fabbr. Down Syndrome and Alzheimer's Disease: Issues and Implications for Social Work Practice. Journal of gerontological social work. vol 61. issue 1. 2019-05-07. PMID:29058538. |
owing to recent medical advancements, people with down syndrome (ds) are now able to live considerably longer lives and thus experience a variety of complex issues as they age. |
2019-05-07 |
2023-08-13 |
Not clear |
| Fabio Ciccarone, Elisabetta Valentini, Marco Malavolta, Michele Zampieri, Maria Giulia Bacalini, Roberta Calabrese, Tiziana Guastafierro, Anna Reale, Claudio Franceschi, Miriam Capri, Nicolle Breusing, Tilman Grune, María Moreno-Villanueva, Alexander Bürkle, Paola Caiaf. DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 73. issue 6. 2019-05-07. PMID:29069286. |
down syndrome (ds) is caused by the presence of part or an entire extra copy of chromosome 21, a phenomenon that can cause a wide spectrum of clinically defined phenotypes of the disease. |
2019-05-07 |
2023-08-13 |
human |