| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raphaele Tsao, Eloise Moy, Jean-Luc Velay, Nicolas Carvalho, Carole Tardi. Handwriting in Children and Adults With Down Syndrome: Developmental Delay or Specific Features? American journal on intellectual and developmental disabilities. vol 122. issue 4. 2019-07-03. PMID:28654414. |
while there is a long history and tradition of behavioral research on basic motor skills in down syndrome (ds), there has been only limited research on handwriting ability. |
2019-07-03 |
2023-08-13 |
human |
| Lizbeth Finestack, Katy H O'Brien, Jolene Hyppa-Martin, Kristen A Lyre. The Evaluation of a Personal Narrative Language Intervention for School-Age Children With Down Syndrome. American journal on intellectual and developmental disabilities. vol 122. issue 4. 2019-07-03. PMID:28654416. |
the purpose of this study was to evaluate the feasibility of an intervention focused on improving personal narrative skills of school-age children with down syndrome (ds) using an approach involving visual supports. |
2019-07-03 |
2023-08-13 |
human |
| Yanyan Liu, Ziyuan Lin, Mingfeng Liu, He Wang, Huaqin Su. Overexpression of DYRK1A, a Down Syndrome Candidate gene, Impairs Primordial Germ Cells Maintenance and Migration in zebrafish. Scientific reports. vol 7. issue 1. 2019-07-03. PMID:29127398. |
dyrk1a, located on chromosome 21, is a major candidate gene of down syndrome (ds, trisomy21), and its overexpression is associated with abnormal phenotype of down syndrome patients. |
2019-07-03 |
2023-08-13 |
human |
| Young M Lee, Bruna L Zampieri, Jonah J Scott-McKean, Mark W Johnson, Alberto C S Cost. Generation of Integration-Free Induced Pluripotent Stem Cells from Urine-Derived Cells Isolated from Individuals with Down Syndrome. Stem cells translational medicine. vol 6. issue 6. 2019-06-27. PMID:28371411. |
down syndrome (ds) is a genetic disorder caused by trisomy 21 (t21). |
2019-06-27 |
2023-08-13 |
mouse |
| Alexandre Hennequin, Amélie Rochet-Capellan, Silvain Gerber, Marion Dohe. Does the Visual Channel Improve the Perception of Consonants Produced by Speakers of French With Down Syndrome? Journal of speech, language, and hearing research : JSLHR. vol 61. issue 4. 2019-06-20. PMID:29635399. |
this work evaluates whether seeing the speaker's face could improve the speech intelligibility of adults with down syndrome (ds). |
2019-06-20 |
2023-08-13 |
Not clear |
| Lin Jiajin, Cao Shuyan, Wu Ying, Chen Junxiao, Wang Xiud. Genetic polymorphisms in folate metabolism as risk for Down syndrome in the southern China. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. vol 32. issue 12. 2019-06-18. PMID:29343135. |
to assess the association between maternal gene polymorphisms of the enzymes involved in folate metabolism and the risk of having a down syndrome (ds) offspring in southern china mothers. |
2019-06-18 |
2023-08-13 |
Not clear |
| Alain D Dekker, Silvia Sacco, Angelo Carfi, Bessy Benejam, Yannick Vermeiren, Gonny Beugelsdijk, Mieke Schippers, Lyanne Hassefras, José Eleveld, Sharina Grefelman, Roelie Fopma, Monique Bomer-Veenboer, Mariángeles Boti, G Danielle E Oosterling, Esther Scholten, Marleen Tollenaere, Laura Checkley, André Strydom, Gert Van Goethem, Graziano Onder, Rafael Blesa, Christine Zu Eulenburg, Antonia M W Coppus, Anne-Sophie Rebillat, Juan Fortea, Peter P De Dey. The Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) Scale: Comprehensive Assessment of Psychopathology in Down Syndrome. Journal of Alzheimer's disease : JAD. vol 63. issue 2. 2019-06-18. PMID:29689719. |
people with down syndrome (ds) are prone to develop alzheimer's disease (ad). |
2019-06-18 |
2023-08-13 |
Not clear |
| A Garg, A Strunk, M Midura, V Papagermanos, H Pomerant. Prevalence of hidradenitis suppurativa among patients with Down syndrome: a population-based cross-sectional analysis. The British journal of dermatology. vol 178. issue 3. 2019-06-17. PMID:28662304. |
hidradenitis suppurativa (hs) has been linked to down syndrome (ds). |
2019-06-17 |
2023-08-13 |
Not clear |
| Yuko Yamauchi, Sayaka Aoki, Junko Koike, Naomi Hanzawa, Keiji Hashimot. Motor and cognitive development of children with Down syndrome: The effect of acquisition of walking skills on their cognitive and language abilities. Brain & development. vol 41. issue 4. 2019-06-17. PMID:30503574. |
this study investigated the relationship between motor and cognitive/language development in children with down syndrome (ds). |
2019-06-17 |
2023-08-13 |
Not clear |
| Helena Ahlfors, Nneka Anyanwu, Edvinas Pakanavicius, Natalia Dinischiotu, Eva Lana-Elola, Sheona Watson-Scales, Justin Tosh, Frances Wiseman, James Briscoe, Karen Page, Elizabeth M C Fisher, Victor L J Tybulewic. Gene expression dysregulation domains are not a specific feature of Down syndrome. Nature communications. vol 10. issue 1. 2019-06-17. PMID:31171815. |
down syndrome (ds), trisomy of human chromosome 21 (hsa21), results in a broad range of phenotypes. |
2019-06-17 |
2023-08-13 |
mouse |
| Robert E Goldsby, Kayla L Stratton, Shannon Raber, Arthur Ablin, Louise C Strong, Kevin Oeffinger, Charles A Sklar, Gregory T Armstrong, Leslie L Robison, Smita Bhatia, Wendy M Leisenrin. Long-term sequelae in survivors of childhood leukemia with Down syndrome: A childhood cancer survivor study report. Cancer. vol 124. issue 3. 2019-06-11. PMID:29105081. |
children with down syndrome (ds) are at increased risk of developing acute leukemia and are more prone to acute toxicities. |
2019-06-11 |
2023-08-13 |
Not clear |
| Sarah R Akkina, Cheng C Ma, Erin M Kirkham, David L Horn, Maida L Chen, Sanjay R Parik. Does drug induced sleep endoscopy-directed surgery improve polysomnography measures in children with Down Syndrome and obstructive sleep apnea? Acta oto-laryngologica. vol 138. issue 11. 2019-06-11. PMID:30776267. |
children with down syndrome (ds) and obstructive sleep apnea (osa) are difficult to treat, as first line therapies may not lead to significant improvement. |
2019-06-11 |
2023-08-13 |
Not clear |
| Marisa A Bartz-Kurycki, Kathryn T Anderson, Mary T Austin, Lillian S Kao, KuoJen Tsao, Kevin P Lally, Akemi L Kawaguch. Increased complications in pediatric surgery are associated with comorbidities and not with Down syndrome itself. The Journal of surgical research. vol 230. 2019-06-10. PMID:30100027. |
down syndrome (ds) is a genetic condition associated with multiple comorbidities. |
2019-06-10 |
2023-08-13 |
Not clear |
| Alex George, Shriram Venkatesan, Narmada Ashok, Radha Saraswathy, M Prakash Hand. Assessment of genomic instability and proliferation index in cultured lymphocytes of patients with Down syndrome, congenital anomalies and aplastic anaemia. Mutation research. Genetic toxicology and environmental mutagenesis. vol 836. issue Pt A. 2019-06-10. PMID:30389169. |
one hundred and fifteen cases [down syndrome (ds) n = 75, multiple congenital anomalies (mca) n = 15 and aplastic anaemia (aa) n = 25], with respect to their nature of predisposition to cancer, were selected for clinical, cytogenetic and cyto-molecular studies to understand the severity of genomic instability according to the nature of the different diseases. |
2019-06-10 |
2023-08-13 |
Not clear |
| Rosemary Sc Horne, Poornima Wijayaratne, Gillian M Nixon, Lisa M Walte. Sleep and sleep disordered breathing in children with down syndrome: Effects on behaviour, neurocognition and the cardiovascular system. Sleep medicine reviews. vol 44. 2019-06-10. PMID:30576943. |
down syndrome (ds), the most common human chromosomal malformation, has an estimated annual incidence of one in 1000 live births worldwide. |
2019-06-10 |
2023-08-13 |
human |
| Noémie Gensous, Claudio Franceschi, Stefano Salvioli, Paolo Garagnani, Maria Giulia Bacalin. Down Syndrome, Ageing and Epigenetics. Sub-cellular biochemistry. vol 91. 2019-06-10. PMID:30888653. |
during the past decades, life expectancy of subjects with down syndrome (ds) has greatly improved, but age-specific mortality rates are still important and ds subjects are characterized by an acceleration of the ageing process, which affects particularly the immune and central nervous systems. |
2019-06-10 |
2023-08-13 |
human |
| Carolina Corsi, Veronica Cimolin, Paolo Capodaglio, Claudia Condoluci, Manuela Gall. A biomechanical study of gait initiation in Down syndrome. BMC neurology. vol 19. issue 1. 2019-06-10. PMID:30987596. |
individuals with down syndrome (ds) walk with low velocity, prolonged stance and shorter steps beside an increased support base. |
2019-06-10 |
2023-08-13 |
human |
| Yvonne S Davidson, Andrew Robinson, Vee P Prasher, David M A Man. The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer's disease in individuals with Down syndrome. Acta neuropathologica communications. vol 6. issue 1. 2019-06-04. PMID:29973279. |
because individuals with down syndrome (ds) (trisomy 21) develop the full pathological changes of ad in a predictable way by the time they reach middle to late age, a study of the brains of such persons at different ages makes an ideal 'model system' in which the sites of earliest onset of pathology can be detected and the subsequent progression of changes be monitored. |
2019-06-04 |
2023-08-13 |
Not clear |
| Anke Bletsch, Caroline Mann, Derek S Andrews, Eileen Daly, Giles M Y Tan, Declan G M Murphy, Christine Ecke. Down syndrome is accompanied by significantly reduced cortical grey-white matter tissue contrast. Human brain mapping. vol 39. issue 10. 2019-06-03. PMID:29885016. |
increased cortical thickness (ct) has been reported in down syndrome (ds) during childhood and adolescence, but it remains unclear, which components of the neural architecture underpin these increases and if ct remains altered in adults. |
2019-06-03 |
2023-08-13 |
Not clear |
| Andrea Giacomini, Fiorenza Stagni, Marco Emili, Sandra Guidi, Maria Elisa Salvalai, Mariagrazia Grilli, Veronica Vidal-Sanchez, Carmen Martinez-Cué, Renata Bartesagh. Treatment with corn oil improves neurogenesis and cognitive performance in the Ts65Dn mouse model of Down syndrome. Brain research bulletin. vol 140. 2019-05-30. PMID:29935232. |
individuals with down syndrome (ds), a genetic condition due to triplication of chromosome 21, are characterized by intellectual disability that worsens with age. |
2019-05-30 |
2023-08-13 |
mouse |