| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aurélien Guffroy, Yannick Dieudonné, Beatrice Uring-Lambert, Joelle Goetz, Yves Alembik, Anne-Sophie Korgano. Infection risk among adults with down syndrome: a two group series of 101 patients in a tertiary center. Orphanet journal of rare diseases. vol 14. issue 1. 2019-05-06. PMID:30634988. |
down syndrome (ds) is the most common form of viable chromosomal abnormality. |
2019-05-06 |
2023-08-13 |
Not clear |
| Qing Mu, Weidong Yu, Shuying Zheng, Hongxia Shi, Mei Li, Jie Sun, Di Wang, Xiaoli Hou, Ling Liu, Xinjuan Wang, Zhuran Zhao, Rong Liang, Xue Zhang, Wei Dong, Chaomei Zeng, Jingzhu Gu. RIP140/PGC-1α axis involved in vitamin A-induced neural differentiation by increasing mitochondrial function. Artificial cells, nanomedicine, and biotechnology. vol 46. issue sup1. 2019-04-30. PMID:29513101. |
vitamin a deficiency and mitochondrial dysfunction are both associated with neural differentiation-related disorders, such as alzheimer's disease (ad) and down syndrome (ds). |
2019-04-30 |
2023-08-13 |
human |
| Hai-Qin Huo, Zhuang-Yin Qu, Fang Yuan, Lixiang Ma, Lin Yao, Min Xu, Yao Hu, Jing Ji, Anita Bhattacharyya, Su-Chun Zhang, Yan Li. Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons. Stem cell reports. vol 10. issue 4. 2019-04-23. PMID:29526735. |
the brain of down syndrome (ds) patients exhibits fewer interneurons in the cerebral cortex, but its underlying mechanism remains unknown. |
2019-04-23 |
2023-08-13 |
mouse |
| Mina Yousefelahiyeh, Jingyi Xu, Estibaliz Alvarado, Yang Yu, David Salven, Robert M Nisse. DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B. PloS one. vol 13. issue 11. 2019-04-22. PMID:30496304. |
overexpression of the dual-specificity tyrosine phosphorylation-regulated kinase 1a (dyrk1a) gene contributes to the retardation, craniofacial anomalies, cognitive impairment, and learning and memory deficits associated with down syndrome (ds). |
2019-04-22 |
2023-08-13 |
mouse |
| Matthew Beerse, Michael Lelko, Jianhua W. Biomechanical analysis of the timed up-and-go (TUG) test in children with and without Down syndrome. Gait & posture. vol 68. 2019-04-22. PMID:30594868. |
considering children with down syndrome (ds) have been shown to take longer to complete the tug test, it is imperative to identify which tasks are problematic for this population in order to individualize physical interventions. |
2019-04-22 |
2023-08-13 |
Not clear |
| Ga Eun Kim, Dal Sik Sin, Seung Soo Kim, Chang-Ho Lee, Nam-Jun Cho, Eun Young Le. End-stage renal disease in a Down syndrome patient caused by delayed diagnosis of nonneurogenic bladder: A case report. Medicine. vol 98. issue 15. 2019-04-22. PMID:30985687. |
patients with down syndrome (ds) have a higher incidence of nonneurogenic neurogenic bladder (nnb) than do normal subjects. |
2019-04-22 |
2023-08-13 |
human |
| Matthew Beerse, Gena Henderson, Huaqing Liang, Toyin Ajisafe, Jianhua W. Variability of spatiotemporal gait parameters in children with and without Down syndrome during treadmill walking. Gait & posture. vol 68. 2019-04-18. PMID:30504087. |
increasing walking speed and including bilateral external ankle load have been shown to improve aspects of the gait pattern of children with down syndrome (ds). |
2019-04-18 |
2023-08-13 |
Not clear |
| Haldun Arpacı, Omer Erkan Yapc. Amniotic fluid NF-kB concentration in pregnant women with a high risk of prenatal screening test results. Ginekologia polska. vol 89. issue 10. 2019-04-17. PMID:30393848. |
this study aimed to determine whether the concentration of nf-kb changes in the amniotic fluid (af) of pregnant women who have a high risk of fetal down syndrome (ds) results in prenatal screening and diagnosis testing. |
2019-04-17 |
2023-08-13 |
Not clear |
| Melissa J Alldred, Helen M Chao, Sang Han Lee, Judah Beilin, Brian E Powers, Eva Petkova, Barbara J Strupp, Stephen D Ginsber. CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation. Hippocampus. vol 28. issue 4. 2019-04-15. PMID:29394516. |
although there are changes in gene expression and alterations in neuronal density and afferent inputs in the forebrain of trisomic mouse models of down syndrome (ds) and alzheimer's disease (ad), there is a lack of systematic assessments of gene expression and encoded proteins within individual vulnerable cell populations, precluding translational investigations at the molecular and cellular level. |
2019-04-15 |
2023-08-13 |
mouse |
| Aurelia Alimi, Jessica Taytard, Rola Abou Taam, Véronique Houdouin, Aude Forgeron, Marc Lubrano Lavadera, Pierrick Cros, Isabelle Gibertini, Jocelyne Derelle, Antoine Deschildre, Caroline Thumerelle, Ralph Epaud, Philippe Reix, Michael Fayon, Sylvie Roullaud, Françoise Troussier, Marie-Catherine Renoux, Jacques de Blic, Sophie Leyronnas, Guillaume Thouvenin, Caroline Perisson, Aimé Ravel, Annick Clement, Harriet Corvol, Nadia Natha. Pulmonary hemosiderosis in children with Down syndrome: a national experience. Orphanet journal of rare diseases. vol 13. issue 1. 2019-04-15. PMID:29678139. |
a previous study from the french respirare® network led to two important findings: 20% of the children presented with both pulmonary hemosiderosis and down syndrome (ds), and at least one tested autoantibody was found positive in 50%. |
2019-04-15 |
2023-08-13 |
Not clear |
| Andrea Kelly, Samuel S Gidding, Rachel Walega, Claire Cochrane, Sarah Clauss, Ray R Townsend, Melissa Xanthopoulos, Mary E Pipan, Babette S Zemel, Sheela N Magge, Meryl S Cohe. Relationships of Body Composition to Cardiac Structure and Function in Adolescents With Down Syndrome are Different than in Adolescents Without Down Syndrome. Pediatric cardiology. vol 40. issue 2. 2019-04-12. PMID:30386863. |
median survival in down syndrome (ds) is 60 years, but cardiovascular disease risk and its markers such as left ventricular mass (lvm) have received limited attention. |
2019-04-12 |
2023-08-13 |
Not clear |
| Kenichiro Watanab. Recent advances in the understanding of transient abnormal myelopoiesis in Down syndrome. Pediatrics international : official journal of the Japan Pediatric Society. vol 61. issue 3. 2019-04-12. PMID:30593694. |
neonates with down syndrome (ds) have a propensity to develop the unique myeloproliferative disorder, transient abnormal myelopoiesis (tam). |
2019-04-12 |
2023-08-13 |
mouse |
| Juan José Casañas, Macarena González-Corrales, Jesús David Urbano-Gámez, Alexandra Alves-Sampaio, José Antonio Troca-Marín, María Luz Montesino. CPEB1 is overexpressed in neurons derived from Down syndrome IPSCs and in the hippocampus of the mouse model Ts1Cje. Molecular and cellular neurosciences. vol 95. 2019-04-11. PMID:30763690. |
trisomy 21, also known as down syndrome (ds), is the most frequent genetic cause of intellectual impairment. |
2019-04-11 |
2023-08-13 |
mouse |
| Marius Flasinski, Kira Scheibke, Martin Zimmermann, Ursula Creutzig, Katarina Reinhardt, Femke Verwer, Valerie de Haas, Vincent H J van der Velden, Christine von Neuhoff, C Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusman. Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study. Blood advances. vol 2. issue 13. 2019-04-08. PMID:29959152. |
approximately 5% to 10% of children with down syndrome (ds) are diagnosed with transient myeloproliferative disorder (tmd). |
2019-04-08 |
2023-08-13 |
Not clear |
| Krutika Joshi, Lily Shen, Feng Cao, Susan Dong, Zhengping Jia, Miguel A Cortez, O Carter Snea. Kcnj6(GIRK2) trisomy is not sufficient for conferring the susceptibility to infantile spasms seen in the Ts65Dn mouse model of down syndrome. Epilepsy research. vol 145. 2019-04-05. PMID:29929098. |
children with down syndrome (ds) are particularly vulnerable to is. |
2019-04-05 |
2023-08-13 |
mouse |
| Jessica Hoffne. Early Detection and Aggressive Management of Otologic Pathologies in Children with Down Syndrome. ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses. vol 35. issue 1. 2019-04-05. PMID:30596482. |
a 13-year-old boy with down syndrome (ds) presents to the pediatric otolaryngologist after being lost to follow-up for several years. |
2019-04-05 |
2023-08-13 |
Not clear |
| F Ricci, S Stagi, F Messa, M de Martin. Neonatal cholelithiasis in Down syndrome: Is hypothyroidism involved? A case-report. Journal of neonatal-perinatal medicine. vol 11. issue 4. 2019-04-03. PMID:30149478. |
we report a 3-month-old male with down syndrome (ds), prolonged jaundice and poor weight gain, that showed biliary lithiasis and undiagnosed congenital hypothyroidism (ch).ch should be considered in ds, especially in presence of gastrointestinal symptoms or malformations. |
2019-04-03 |
2023-08-13 |
Not clear |
| Huaqing Liang, Xiang Ke, Jianhua W. Transitioning from the level surface to stairs in children with and without Down syndrome: Motor strategy and anticipatory locomotor adjustments. Gait & posture. vol 66. 2019-04-01. PMID:30223209. |
children with down syndrome (ds) show underdeveloped motor strategy and anticipatory locomotor adjustments (ala) before crossing an obstacle. |
2019-04-01 |
2023-08-13 |
Not clear |
| Chiara Lanzillotta, Antonella Tramutola, Shelby Meier, Frederick Schmitt, Eugenio Barone, Marzia Perluigi, Fabio Di Domenico, Jose F Abisambr. Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models. Journal of Alzheimer's disease : JAD. vol 62. issue 1. 2019-03-25. PMID:29439332. |
down syndrome (ds) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans, which results from the triplication of chromosome 21. |
2019-03-25 |
2023-08-13 |
mouse |
| Flávia Scalioni, Camila Faria Carrada, Lucas Abreu, Rosangela Almeida Ribeiro, Saul Martins Paiv. Perception of parents/caregivers on the oral health of children/adolescents with Down syndrome. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 38. issue 6. 2019-03-25. PMID:30184266. |
oral health affects the general health of people with down syndrome (ds), with repercussions on their ability to chew and to communicate. |
2019-03-25 |
2023-08-13 |
Not clear |