| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolás Gómez Álvarez, Alexandra Venegas Mortecinos, Valentina Zapata Rodríguez, Miguel López Fontanilla, Matías Maudier Vásquez, Gustavo Pavez-Adasme, Claudio Hemández-Mosqueir. [Effect of an intervention based on virtual reality on motor development and postural control in children with Down Syndrome]. Revista chilena de pediatria. vol 89. issue 6. 2019-02-19. PMID:30725064. |
there are few studies on the effect of a virtual reality-based intervention on motor development and postural control in children with down syndrome (ds). |
2019-02-19 |
2023-08-13 |
Not clear |
| Jacqueline London, Claude Rouch, Linh Chi Bui, Elodie Assayag, Benoit Souchet, Fabrice Daubigney, Hind Medjaoui, Serge Luquet, Christophe Magnan, Jean Maurice Delabar, Julien Dairou, Nathalie Jane. Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues. Molecular neurobiology. vol 55. issue 5. 2019-02-18. PMID:28540658. |
trisomy 21 (t21) or down syndrome (ds) is the most common genetic disorder associated with intellectual disability and affects around 5 million persons worldwide. |
2019-02-18 |
2023-08-13 |
mouse |
| Miguel Bellés, Josep Carbonell, José M Blasco-Ibáñez, Carlos Crespo, Juan Nácher, Emilio Vare. Alterations in reelin and reelin receptors in Down syndrome. Neuroreport. vol 30. issue 1. 2019-02-13. PMID:30395007. |
individuals with down syndrome (ds) present an early development of ad; therefore, we analyzed the alterations in this molecule and its receptors in the murine model for ds ts65dn as well as in human with ds. |
2019-02-13 |
2023-08-13 |
mouse |
| Bianca Fox, Gwendolyn E Moffett, Clara Kinnison, Grace Brooks, Laura E Cas. Physical Activity Levels of Children With Down Syndrome. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 31. issue 1. 2019-02-12. PMID:30507856. |
this systematic review of literature analyzed accelerometer use to measure physical activity (pa) in individuals 21 years and younger with down syndrome (ds). |
2019-02-12 |
2023-08-13 |
Not clear |
| Michelle McGuire, Jason Long, Anna J Esbensen, Amy F Baile. Adapted Dance Improves Motor Abilities and Participation in Children With Down Syndrome: A Pilot Study. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. vol 31. issue 1. 2019-02-12. PMID:30557286. |
this pilot study measured effects of an adapted dance program on motor abilities and participation in children with down syndrome (ds) and explored caregivers' qualitative feedback regarding its benefits. |
2019-02-12 |
2023-08-13 |
Not clear |
| Alain D Dekker, Yannick Vermeiren, Gonny Beugelsdijk, Mieke Schippers, Lyanne Hassefras, José Eleveld, Sharina Grefelman, Roelie Fopma, Monique Bomer-Veenboer, G Danielle E Oosterling, Esther Scholten, Marleen Tollenaere, Gert Van Goethem, Christine Zu Eulenburg, Antonia M W Coppus, Peter P De Dey. [The behavioral and psychological symptoms of dementia in down syndrome (BPSD-DS) scale: comprehensive assessment of psychopathology in down syndrome]. Tijdschrift voor gerontologie en geriatrie. vol 49. issue 5. 2019-02-11. PMID:30238286. |
structured interviews were conducted with informants of people with down syndrome without dementia (ds, n = 149), with questionable dementia (ds + td, n = 65) and with diagnosed dementia (ds + ad, n = 67). |
2019-02-11 |
2023-08-13 |
Not clear |
| Samire Beqaj, Esmira E T Tërshnjaku, Merita Qorolli, Vujica Zivkovi. Contribution of Physical and Motor Characteristics to Functional Performance in Children and Adolescents with Down Syndrome: A Preliminary Study. Medical science monitor basic research. vol 24. 2019-02-11. PMID:30323163. |
background down syndrome (ds) is the most frequent genetic mental disability. |
2019-02-11 |
2023-08-13 |
human |
| Chandni Parikh, Ann M Mastergeorg. Vocalization patterns in young children with Down syndrome: Utilizing the language environment analysis (LENA) to inform behavioral phenotypes. Journal of intellectual disabilities : JOID. vol 22. issue 4. 2019-02-06. PMID:28485651. |
children with down syndrome (ds) are at higher risk for both delayed expressive language and poor speech intelligibility. |
2019-02-06 |
2023-08-13 |
Not clear |
| L De Schrijver, V Topsakal, M Wojciechowski, P Van de Heyning, A Boudewyn. Prevalence and etiology of sensorineural hearing loss in children with down syndrome: A cross-sectional study. International journal of pediatric otorhinolaryngology. vol 116. 2019-02-06. PMID:30554691. |
the prevalence and causes of sensorineural hearing loss (snhl) in children with down syndrome (ds) are poorly delineated. |
2019-02-06 |
2023-08-13 |
Not clear |
| Jen-Chieh Chiang, Jun Jiang, Peter E Newburger, Jeanne B Lawrenc. Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro. Nature communications. vol 9. issue 1. 2019-02-05. PMID:30518921. |
we previously demonstrated that an integrated xist transgene can broadly repress one chromosome 21 in down syndrome (ds) pluripotent cells. |
2019-02-05 |
2023-08-13 |
human |
| Bruno H S Araujo, Carolini Kaid, Janaina S De Souza, Sérgio Gomes da Silva, Ernesto Goulart, Luiz C J Caires, Camila M Musso, Laila B Torres, Adriano Ferrasa, Roberto Herai, Mayana Zatz, Oswaldo K Okamoto, Esper A Cavalheir. Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro. Molecular neurobiology. vol 55. issue 7. 2019-02-04. PMID:29128905. |
several methods have been used to study the neuropathogenesis of down syndrome (ds), such as mouse aneuploidies, post mortem human brains, and in vitro cell culture of neural progenitor cells. |
2019-02-04 |
2023-08-13 |
mouse |
| Raquel Coronel, Adela Bernabeu-Zornoza, Charlotte Palmer, Mar Muñiz-Moreno, Alberto Zambrano, Eva Cano, Isabel List. Role of Amyloid Precursor Protein (APP) and Its Derivatives in the Biology and Cell Fate Specification of Neural Stem Cells. Molecular neurobiology. vol 55. issue 9. 2019-02-04. PMID:29383688. |
furthermore, it is believed that individuals with down syndrome (ds) have increased app expression, due to an extra copy of chromosome 21 (hsa21), that contains the gene for app. |
2019-02-04 |
2023-08-13 |
Not clear |
| Adrian A Ong, Carlyn M Atwood, Shaun A Nguyen, Ronald J Teufel, Chitra Lal, Angela C LaRosa, David R Whit. Down syndrome and pediatric obstructive sleep apnea surgery: A national cohort. The Laryngoscope. vol 128. issue 8. 2019-01-31. PMID:29280489. |
to analyze the trend of sleep surgeries in pediatric patients with down syndrome (ds) and obstructive sleep apnea (osa), and to compare this to nonsyndromic (ns) children with osa. |
2019-01-31 |
2023-08-13 |
Not clear |
| Babette van de Wiel, Marjolein van Loon, Wimke Reuland, Josef Bruer. Periodontal disease in Down's syndrome patients. A retrospective study. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 38. issue 5. 2019-01-31. PMID:30044508. |
the purpose of this study was to assess the periodontal condition of people with down syndrome (ds). |
2019-01-31 |
2023-08-13 |
Not clear |
| Edoardo Moretto, Luca Murru, Giuseppe Martano, Jenny Sassone, Maria Passafar. Glutamatergic synapses in neurodevelopmental disorders. Progress in neuro-psychopharmacology & biological psychiatry. vol 84. issue Pt B. 2019-01-30. PMID:28935587. |
we summarize present knowledge on autism spectrum disorders (asd), intellectual disability (id), down syndrome (ds), rett syndrome (rs) and attention-deficit hyperactivity disorder (adhd), highlighting the involvement of glutamatergic synapses and receptors in these disorders. |
2019-01-30 |
2023-08-13 |
Not clear |
| Katarzyna Stachowic. The role of DSCAM in the regulation of synaptic plasticity: possible involvement in neuropsychiatric disorders. Acta neurobiologiae experimentalis. vol 78. issue 3. 2019-01-30. PMID:30295678. |
finally, the review throws some light on the possible involvement of dscam in a spectrum of psychiatric disorders apart from down syndrome (ds). |
2019-01-30 |
2023-08-13 |
Not clear |
| Vicky Duffy, Daniel Gomez, Peter Rycus, Brian Rivera, Stephanie L Santoro, Carl H Backes, Clifford L Cu. Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Adult Patients With Down Syndrome. Artificial organs. vol 42. issue 9. 2019-01-29. PMID:29774549. |
patients with down syndrome (ds) may have multiple medical issues that place them at risk for requiring extracorporeal membrane oxygenation. |
2019-01-29 |
2023-08-13 |
Not clear |
| Corrado Di Mambro, Camilla Calvieri, Massimo Stefano Silvetti, Ilaria Tamburri, Salvatore Giannico, Anwar Baban, Sonia Albanese, Gianluca Brancaccio, Adriano Carotti, Fiore Salvatore Iorio, Fabrizio Drag. Bradyarrhythmias in Repaired Atrioventricular Septal Defects: Single-Center Experience Based on 34 Years of Follow-Up of 522 Patients. Pediatric cardiology. vol 39. issue 8. 2019-01-28. PMID:29948031. |
atrioventricular septal defect (avsd) is a rare congenital heart defect (chd) often associated with genetic syndromes, most commonly down syndrome (ds). |
2019-01-28 |
2023-08-13 |
Not clear |
| Giulia Giovanardi, Andrea Chiricozzi, Luca Bianchi, Clara De Simone, Valentina Dini, Chiara Franceschini, Simone Garcovich, Teresa Oranges, Cosimo Di Raimondo, Dante Raffaele Caposiena Caro, Marco Romanelli, Ketty Peri. Hidradenitis Suppurativa Associated with Down Syndrome Is Characterized by Early Age at Diagnosis. Dermatology (Basel, Switzerland). vol 234. issue 1-2. 2019-01-25. PMID:29689550. |
the association between hidradenitis suppurativa (hs) and multiple comorbidities has been widely investigated but data about the coexistence of down syndrome (ds) are scarce. |
2019-01-25 |
2023-08-13 |
Not clear |
| Donna M Wilcock, Frederick A Schmitt, Elizabeth Hea. Cerebrovascular contributions to aging and Alzheimer's disease in Down syndrome. Biochimica et biophysica acta. vol 1862. issue 5. 2019-01-24. PMID:26593849. |
down syndrome (ds) is a common cause of intellectual disability and is also associated with early age of onset of alzheimer's disease (ad). |
2019-01-24 |
2023-08-13 |
Not clear |