| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olivia Miu Yung Ngan, Huso Yi, Shenaz Ahme. Service provision of non-invasive prenatal testing for Down syndrome in public and private healthcare sectors: a qualitative study with obstetric providers. BMC health services research. vol 18. issue 1. 2018-12-11. PMID:30241520. |
cell-free fetal dna sequencing based non-invasive prenatal testing (nipt) for down syndrome (ds) has become widely available. |
2018-12-11 |
2023-08-13 |
Not clear |
| Usman Bala, Melody Pui-Yee Leong, Chai Ling Lim, Hayati Kadir Shahar, Fauziah Othman, Mei-I Lai, Zhe-Kang Law, Khairunnisa Ramli, Ohnmar Htwe, King-Hwa Ling, Pike-See Chea. Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model. PloS one. vol 13. issue 5. 2018-11-26. PMID:29795634. |
down syndrome (ds) is a genetic disorder caused by presence of extra copy of human chromosome 21. |
2018-11-26 |
2023-08-13 |
mouse |
| Monika Zbucka-Kretowska, Karol Charkiewicz, Jan Czerniecki, Joanna Goscik, Slawomir Wolczynski, Piotr Laudansk. Amniotic Fluid Angiogenic and Inflammatory Factor Profiling in Foetal Down Syndrome. Fetal diagnosis and therapy. vol 44. issue 1. 2018-11-19. PMID:28715807. |
the goal of this study was to determine the concentrations of 60 angiogenic factors in the amniotic fluid of women carrying foetuses with down syndrome (ds). |
2018-11-19 |
2023-08-13 |
Not clear |
| Goncalo V Mendonca, Afonso Borges, Sang O Wee, Bo Fernhal. Oxygen uptake efficiency slope during exercise in adults with Down syndrome. Journal of applied research in intellectual disabilities : JARID. vol 31. issue 5. 2018-11-15. PMID:29573317. |
persons with down syndrome (ds) have low aerobic exercise capacity. |
2018-11-15 |
2023-08-13 |
Not clear |
| Syed Faraz Kazim, Julie Blanchard, Riccardo Bianchi, Khalid Iqba. Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer's-like memory deficits in the Ts65Dn mouse model of Down syndrome. Scientific reports. vol 7. 2018-11-14. PMID:28368015. |
down syndrome (ds), caused by trisomy 21, is the most common genetic cause of intellectual disability and is associated with a greatly increased risk of early-onset alzheimer's disease (ad). |
2018-11-14 |
2023-08-13 |
mouse |
| A Block, Md M Ahmed, N Rueda, M-C Hernandez, C Martinez-Cué, K J Gardine. The GABA Neuroscience. vol 372. 2018-11-13. PMID:29292072. |
the gaba down syndrome (ds), trisomy of human chromosome 21 (hsa21), is the most common genetic cause of intellectual disability (id). |
2018-11-13 |
2023-08-13 |
mouse |
| Sarah Edie, Norann A Zaghloul, Carmen C Leitch, Donna K Klinedinst, Janette Lebron, Joey F Thole, Andrew S McCallion, Nicholas Katsanis, Roger H Reeve. Survey of Human Chromosome 21 Gene Expression Effects on Early Development in G3 (Bethesda, Md.). vol 8. issue 7. 2018-11-08. PMID:29760202. |
survey of human chromosome 21 gene expression effects on early development in trisomy for human chromosome 21 (hsa21) results in down syndrome (ds), one of the most genetically complex conditions compatible with human survival. |
2018-11-08 |
2023-08-13 |
human |
| Winston Y Lee, Olga K Weinberg, Andrew G Evans, Geraldine S Pinku. Loss of Full-Length GATA1 Expression in Megakaryocytes Is a Sensitive and Specific Immunohistochemical Marker for the Diagnosis of Myeloid Proliferative Disorder Related to Down Syndrome. American journal of clinical pathology. vol 149. issue 4. 2018-11-07. PMID:29481579. |
myeloid proliferative disorders associated with down syndrome (mpd-ds), including transient abnormal myelopoiesis and myeloid leukemia associated with down syndrome (ds), harbor mutations of gata1, a transcription factor essential for erythroid and megakaryocytic development. |
2018-11-07 |
2023-08-13 |
Not clear |
| Lesley Doyle, Kathryn J Saunders, Julie-Anne Littl. Determining the relative contribution of retinal disparity and blur cues to ocular accommodation in Down syndrome. Scientific reports. vol 7. 2018-11-05. PMID:28071728. |
individuals with down syndrome (ds) often exhibit hypoaccommodation alongside accurate vergence. |
2018-11-05 |
2023-08-13 |
human |
| Laura J Hahn, Susan J Loveall, Madison T Savoy, Allie M Neumann, Toshikazu Ikut. Joint attention in Down syndrome: A meta-analysis. Research in developmental disabilities. vol 78. 2018-11-05. PMID:29793102. |
some studies have indicated that joint attention may be a relative strength in down syndrome (ds), but other studies have not. |
2018-11-05 |
2023-08-13 |
Not clear |
| Evangelia Romanopoulou, Vasiliki Zilidou, Theodore Savvidis, Chariklia Chatzisevastou-Loukidou, Panagiotis Bamidi. Unmet Needs of Persons with Down Syndrome: How Assistive Technology and Game-Based Training May Fill the Gap. Studies in health technology and informatics. vol 251. 2018-11-05. PMID:29968590. |
this study presents an important initial step utilizing the llm care service which focuses on the needs and challenges for the health and daily living of people with down syndrome (ds) by applying new technology hardware and software. |
2018-11-05 |
2023-08-13 |
Not clear |
| Thanh Thi Mai Pham, Hiroki Kato, Haruyoshi Yamaza, Keiji Masuda, Yuta Hirofuji, Hiroshi Sato, Huong Thi Nguyen Nguyen, Xu Han, Yu Zhang, Tomoaki Taguchi, Kazuaki Nonak. Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome. BMC neurology. vol 18. issue 1. 2018-10-31. PMID:30170556. |
down syndrome (ds) is a common developmental disorder resulting from the presence of an additional copy of chromosome 21. |
2018-10-31 |
2023-08-13 |
human |
| Marie-Christine Birling, Laurence Schaeffer, Philippe André, Loic Lindner, Damien Maréchal, Abdel Ayadi, Tania Sorg, Guillaume Pavlovic, Yann Héraul. Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE. Scientific reports. vol 7. 2018-10-29. PMID:28266534. |
modelling down syndrome (ds) in mouse has been crucial for the understanding of the disease and the evaluation of therapeutic targets. |
2018-10-29 |
2023-08-13 |
mouse |
| Marianna Alesi, Giusppe Battaglia, Annamaria Pepi, Antonino Bianco, Antonio Palm. Gross motor proficiency and intellectual functioning: A comparison among children with Down syndrome, children with borderline intellectual functioning, and typically developing children. Medicine. vol 97. issue 41. 2018-10-29. PMID:30313077. |
two motor areas have been investigated as being equally essential to gross motor functions in every-day life: locomotion and object control.it aims to compare gross motor skills endorsed by children with down syndrome (ds), children with borderline intellectual functioning (bif), and typically developing children (tdc).group 1 was composed of 18 children with ds (chronological age = 8.22), group 2 was composed of 18 children with bif (chronological age = 9.32), and group 3 was composed of 18 children with typical development (td) (chronological age = 9.28).gross motor skills were measured through the test of gross motor development (tgmd-test) composed of locomotion and object control tasks.children with ds showed worse gross motor skills compared with children with bif and typically developing children by underscoring both on all locomotion (e.g., walking, running, hopping, galloping, jumping, sliding, and leaping) and all object control tasks (e.g., throwing, catching, striking, bouncing, kicking, pulling, and pushing).in ds group strengths were found on run and slide skills, in bif group strengths were on run, long jump and slide skills and in tdc group strengths were on run and slide skills. |
2018-10-29 |
2023-08-13 |
Not clear |
| Terral A Patel, Shaun A Nguyen, David R Whit. Down Syndrome as an indicator for pediatric otolaryngologic procedures. International journal of pediatric otorhinolaryngology. vol 112. 2018-10-26. PMID:30055730. |
down syndrome (ds) is the most common chromosome abnormality in humans. |
2018-10-26 |
2023-08-13 |
Not clear |
| Tiago Jeronimo Dos Santos, Gabriel Ángel Martos-Moreno, María Teresa Muñoz-Calvo, Jesús Pozo, Fernando Rodríguez-Artalejo, Jesús Argent. Clinical management of childhood hyperthyroidism with and without Down syndrome: a longitudinal study at a single center. Journal of pediatric endocrinology & metabolism : JPEM. vol 31. issue 7. 2018-10-25. PMID:29953411. |
eleven also suffered from down syndrome (ds). |
2018-10-25 |
2023-08-13 |
Not clear |
| Lauren T Ptomey, Amanda N Szabo, Erik A Willis, Anna M Gorczyca, J Leon Greene, Jessica C Danon, Joseph E Donnell. Changes in cognitive function after a 12-week exercise intervention in adults with Down syndrome. Disability and health journal. vol 11. issue 3. 2018-10-24. PMID:29501470. |
between 250,000 and 400,000 individuals in the united states are diagnosed with down syndrome (ds). |
2018-10-24 |
2023-08-13 |
Not clear |
| Melissa Hill, Angela Barrett, Mahesh Choolani, Celine Lewis, Jane Fisher, Lyn S Chitt. Has noninvasive prenatal testing impacted termination of pregnancy and live birth rates of infants with Down syndrome? Prenatal diagnosis. vol 37. issue 13. 2018-10-22. PMID:29111614. |
implementation of noninvasive prenatal testing (nipt) as a highly accurate aneuploidy screening test has raised questions around whether the high uptake may result in more terminations of pregnancies and fewer births of children with down syndrome (ds). |
2018-10-22 |
2023-08-13 |
Not clear |
| Jennifer Best, Sean Mutchnick, Jonathan Ida, Kathleen R Billing. Trends in management of obstructive sleep apnea in pediatric patients with Down syndrome. International journal of pediatric otorhinolaryngology. vol 110. 2018-10-17. PMID:29859566. |
residual obstructive sleep apnea (osa) after adenotonsillectomy (t&a) is a common problem in children with down syndrome (ds). |
2018-10-17 |
2023-08-13 |
Not clear |
| Rebecca A Hardest. Much ado about mice: Standard-setting in model organism research. Studies in history and philosophy of biological and biomedical sciences. vol 68-69. 2018-10-16. PMID:29655519. |
the case i present focuses on a group of neurobiologists researching the genetic underpinnings of cognition in down syndrome (ds) and how they have developed a new mouse model which they argue should be regarded as the "gold standard" for all ds mouse research. |
2018-10-16 |
2023-08-13 |
mouse |