| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David L García-Ramírez, Jorge R Calvo, Shawn Hochman, Jorge N Queved. Serotonin, dopamine and noradrenaline adjust actions of myelinated afferents via modulation of presynaptic inhibition in the mouse spinal cord. PloS one. vol 9. issue 2. 2014-10-28. PMID:24587177. |
ic50 values for drp depression were 0.6, 0.8 and 1.0 µm for 5ht, da and na, respectively. |
2014-10-28 |
2023-08-12 |
mouse |
| David L García-Ramírez, Jorge R Calvo, Shawn Hochman, Jorge N Queved. Serotonin, dopamine and noradrenaline adjust actions of myelinated afferents via modulation of presynaptic inhibition in the mouse spinal cord. PloS one. vol 9. issue 2. 2014-10-28. PMID:24587177. |
5ht, da and na produced no change in the compound antidromic potentials evoked by intraspinal microstimulation indicating that depression of the drp is unrelated to direct changes in the excitability of intraspinal afferent fibers, but due to metabotropic receptor activation. |
2014-10-28 |
2023-08-12 |
mouse |
| Charlotte Bleas. The duty to be well-informed: the case of depression. Journal of medical ethics. vol 40. issue 4. 2014-10-27. PMID:23625738. |
studies on lay understanding of depression show that there is a common belief that depression is wholly caused by a 'chemical imbalance' (such as 'low serotonin') that can be restored by chemically restorative antidepresssants, a claim that has entered 'folk wisdom'. |
2014-10-27 |
2023-08-12 |
Not clear |
| Walter J Astorne Figari, Sandra Herrmann, Clement Akogyeram, Qi Qia. New onset hypertension following abrupt discontinuation of citalopram. Clinical nephrology. vol 82. issue 3. 2014-10-24. PMID:23320970. |
citalopram is one of the selective serotonin re-uptake inhibitors (ssris) most commonly prescribed for depression and many affective disorders. |
2014-10-24 |
2023-08-12 |
Not clear |
| R H McAllister-Williams, H A Alhaj, A Massey, J Pankiv, U Reckerman. Somatodendritic 5-hydroxytryptamine1A (5-HT1A) autoreceptor function in major depression as assessed using the shift in electroencephalographic frequency spectrum with buspirone. Psychological medicine. vol 44. issue 4. 2014-10-22. PMID:23809646. |
positron emission tomography and post-mortem studies of the number of somatodendritic 5-hydroxytryptamine(1a) (5-ht(1a)) autoreceptors in raphé nuclei have found both increases and decreases in depression. |
2014-10-22 |
2023-08-12 |
Not clear |
| Haiying Xu, Qing Zhang, Xuwei Hou, Qingmei Wang, Yizhou Xu, Lulu Li, Ningfu Wan. The effect of the polymorphisms of 5-HTTLPR on new onset of depression in patients who underwent pacemaker implantation. Psychiatric genetics. vol 24. issue 2. 2014-10-22. PMID:24077031. |
to study the role of serotonin transporter gene (5-httlpr) polymorphisms in the incidence of depression in a chinese cohort who underwent pacemaker (pm) implantation. |
2014-10-22 |
2023-08-12 |
Not clear |
| Holly J Engelstad, Robert D Roghair, Chadi A Calarge, Tarah T Colaizy, Scott Stuart, Sarah E Haskel. Perinatal outcomes of pregnancies complicated by maternal depression with or without selective serotonin reuptake inhibitor therapy. Neonatology. vol 105. issue 2. 2014-10-21. PMID:24356332. |
perinatal outcomes of pregnancies complicated by maternal depression with or without selective serotonin reuptake inhibitor therapy. |
2014-10-21 |
2023-08-12 |
Not clear |
| Kenneth D Gadow, Ryan M Smith, Julia K Pinsonneaul. Serotonin 2A receptor gene (HTR2A) regulatory variants: possible association with severity of depression symptoms in children with autism spectrum disorder. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology. vol 27. issue 2. 2014-10-21. PMID:24968012. |
serotonin 2a receptor gene (htr2a) regulatory variants: possible association with severity of depression symptoms in children with autism spectrum disorder. |
2014-10-21 |
2023-08-13 |
Not clear |
| Kenneth D Gadow, Ryan M Smith, Julia K Pinsonneaul. Serotonin 2A receptor gene (HTR2A) regulatory variants: possible association with severity of depression symptoms in children with autism spectrum disorder. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology. vol 27. issue 2. 2014-10-21. PMID:24968012. |
our aim was to characterize the association of 2 functional single nucleotide polymorphisms (rs6311 and rs6314) in the serotonin 2a receptor gene (htr2a) with severity of depression symptoms in children with autism spectrum disorder. |
2014-10-21 |
2023-08-13 |
Not clear |
| Kenneth D Gadow, Ryan M Smith, Julia K Pinsonneaul. Serotonin 2A receptor gene (HTR2A) regulatory variants: possible association with severity of depression symptoms in children with autism spectrum disorder. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology. vol 27. issue 2. 2014-10-21. PMID:24968012. |
these polymorphisms have been shown to be associated with depression symptom severity and response to selective serotonin reuptake inhibitor drugs in adults with diagnosed depressive disorder. |
2014-10-21 |
2023-08-13 |
Not clear |
| Neera Ghaziuddin, Cheryl A King, Kathleen Welch, Mohammad Ghaziuddi. Depressed suicidal adolescent males have an altered cortisol response to a pharmacological challenge. Asian journal of psychiatry. vol 7. issue 1. 2014-10-17. PMID:24524706. |
dysregulation of the hpa axis and the dysfunction of the central serotonin (5ht) system are the most replicated biomarkers of depression and suicidal ideation and behavior. |
2014-10-17 |
2023-08-12 |
Not clear |
| Claus-Jürgen Scholz, Susanne Jungwirth, Walter Danielczyk, Heike Weber, Ildiko Wichart, Karl Heinz Tragl, Peter Fischer, Peter Riederer, Jürgen Deckert, Edna Grünblat. Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: a 90-month longitudinal study. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 165B. issue 2. 2014-10-16. PMID:24443391. |
investigation of association of serotonin transporter and monoamine oxidase-a genes with alzheimer's disease and depression in the vita study cohort: a 90-month longitudinal study. |
2014-10-16 |
2023-08-12 |
human |
| Stephen M Stah. Selectivity of SSRIs: individualising patient care through rational treatment choices. International journal of psychiatry in clinical practice. vol 8 Suppl 1. 2014-10-15. PMID:24930682. |
despite a common mode of action [inhibition of the 5-hydroxytryptamine (5-ht) neuronal reuptake transporter], proven antidepressant efficacy and a similar range of indications (depression and a variety of anxiety disorders), the unique secondary binding properties of each selective serotonin reuptake inhibitor (ssri) account for clinically significant differences in tolerability and side-effect profiles, particularly in some patients. |
2014-10-15 |
2023-08-13 |
Not clear |
| David Nut. Anxiety and depression: individual entities or two sides of the same coin? International journal of psychiatry in clinical practice. vol 8 Suppl 1. 2014-10-15. PMID:24930685. |
selective serotonin reuptake inhibitors (ssris) have shown efficacy in a number of neuroses: depression; obsessive-compulsive disorder (ocd) and anxiety disorders (panic disorder [pd], social anxiety disorder [sad], generalised anxiety disorder and post-traumatic stress disorder). |
2014-10-15 |
2023-08-13 |
Not clear |
| Gordon Parke. Treatment options for real-life patients. International journal of psychiatry in clinical practice. vol 8 Suppl 1. 2014-10-15. PMID:24930688. |
for example, when treating depression associated with anxiety, selective serotonin reuptake inhibitors (ssris) produce a high response in patients with internalised anxious worrying or externalised irritability. |
2014-10-15 |
2023-08-13 |
Not clear |
| b' Zofia Rog\\xc3\\xb3\\xc5\\xb. Combined treatment with atypical antipsychotics and antidepressants in treatment-resistant depression: preclinical and clinical efficacy. Pharmacological reports : PR. vol 65. issue 6. 2014-10-14. PMID:24553002.' |
several clinical reports have documented a beneficial effect of adding atypical antipsychotic drugs to ongoing treatments with antidepressants, particularly selective serotonin reuptake inhibitors, in ameliorating drug-resistant depression. |
2014-10-14 |
2023-08-12 |
rat |
| Tania Rivera-Baltanas, Jose Manuel Olivares, Jose Ramon Martinez-Villamarin, Erin Y Fenton, Lisa E Kalynchuk, Hector J Carunch. Serotonin 2A receptor clustering in peripheral lymphocytes is altered in major depression and may be a biomarker of therapeutic efficacy. Journal of affective disorders. vol 163. 2014-10-14. PMID:24836087. |
serotonin 2a receptor clustering in peripheral lymphocytes is altered in major depression and may be a biomarker of therapeutic efficacy. |
2014-10-14 |
2023-08-13 |
Not clear |
| Tania Rivera-Baltanas, Jose Manuel Olivares, Jose Ramon Martinez-Villamarin, Erin Y Fenton, Lisa E Kalynchuk, Hector J Carunch. Serotonin 2A receptor clustering in peripheral lymphocytes is altered in major depression and may be a biomarker of therapeutic efficacy. Journal of affective disorders. vol 163. 2014-10-14. PMID:24836087. |
in a previous report, we showed that the clustering of serotonin (5ht) transporter (sert) protein on cell membranes of peripheral lymphocytes predicts responsivity to antidepressant medication in two subpopulations of naïve depression patients (rivera-baltanas et al., j affect disord, 2012, 137, 46-55). |
2014-10-14 |
2023-08-13 |
Not clear |
| Alvaro L Garcia-Garcia, Adrian Newman-Tancredi, E David Leonard. 5-HT(1A) [corrected] receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function. Psychopharmacology. vol 231. issue 4. 2014-10-10. PMID:24337875. |
serotonin (5-ht) neurotransmission is intimately linked to anxiety and depression and a diverse body of evidence supports the involvement of the main inhibitory serotonergic receptor, the serotonin-1a (5-ht(1a)) subtype, in both disorders. |
2014-10-10 |
2023-08-12 |
Not clear |
| S Hatta, A Duni, C G Ng, N Lin, M Marhani, S Das, N J Nik Ruzyane. Effects of Selective Serotonin Reuptake Inhibitors (SSRIs) therapy on the female sexual response cycle of women with major depression. La Clinica terapeutica. vol 164. issue 1. 2014-10-09. PMID:23455735. |
effects of selective serotonin reuptake inhibitors (ssris) therapy on the female sexual response cycle of women with major depression. |
2014-10-09 |
2023-08-12 |
Not clear |