| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jillian Lee Wiggins, Jirair K Bedoyan, Melisa Carrasco, Johnna R Swartz, Donna M Martin, Christopher S Mon. Age-related effect of serotonin transporter genotype on amygdala and prefrontal cortex function in adolescence. Human brain mapping. vol 35. issue 2. 2014-09-02. PMID:23124623. |
paradoxically, serotonin transporter blockade relieves depression symptoms. |
2014-09-02 |
2023-08-12 |
human |
| Jillian Lee Wiggins, Jirair K Bedoyan, Melisa Carrasco, Johnna R Swartz, Donna M Martin, Christopher S Mon. Age-related effect of serotonin transporter genotype on amygdala and prefrontal cortex function in adolescence. Human brain mapping. vol 35. issue 2. 2014-09-02. PMID:23124623. |
rodent models suggest that decreased serotonin transporter in early life produces depression that emerges in adolescence, whereas decreased serotonin transporter that occurs later in development ameliorates depression. |
2014-09-02 |
2023-08-12 |
human |
| Melissa Lamar, Michael Craig, Eileen M Daly, William J Cutter, Christine Tang, Michael Brammer, Katya Rubia, Declan G M Murph. Acute tryptophan depletion promotes an anterior-to-posterior fMRI activation shift during task switching in older adults. Human brain mapping. vol 35. issue 2. 2014-09-02. PMID:23281064. |
neural adaptation to serotonin challenge during cognitive control may prove useful in determining cognitive vulnerability in older adults with a predisposition for serontonergic down-regulation (e.g., in vascular or late life depression). |
2014-09-02 |
2023-08-12 |
human |
| Gregor Gryglewski, Rupert Lanzenberger, Georg S Kranz, Paul Cummin. Meta-analysis of molecular imaging of serotonin transporters in major depression. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 7. 2014-09-02. PMID:24802331. |
meta-analysis of molecular imaging of serotonin transporters in major depression. |
2014-09-02 |
2023-08-13 |
human |
| Omar T Sims, Christopher C Whalen, Larry G Nackerud, Brian E Brid. Longitudinal effects of selective serotonin reuptake inhibitor therapy and cytokine-related depression on hepatitis C viral logs during antiviral therapy. Journal of clinical psychopharmacology. vol 34. issue 1. 2014-08-29. PMID:24135839. |
longitudinal effects of selective serotonin reuptake inhibitor therapy and cytokine-related depression on hepatitis c viral logs during antiviral therapy. |
2014-08-29 |
2023-08-12 |
Not clear |
| Omar T Sims, Christopher C Whalen, Larry G Nackerud, Brian E Brid. Longitudinal effects of selective serotonin reuptake inhibitor therapy and cytokine-related depression on hepatitis C viral logs during antiviral therapy. Journal of clinical psychopharmacology. vol 34. issue 1. 2014-08-29. PMID:24135839. |
the aim of this study was to determine the longitudinal effects of selective serotonin reuptake inhibitor (ssri) therapy and cytokine-related depression on levels of hepatitis c virus (hcv) during treatment with combination therapy. |
2014-08-29 |
2023-08-12 |
Not clear |
| Dan A Kim, Willie G McClure, Jordan B Neighoff, Dhananjay Vaidya, Marlene S William. Platelet response to serotonin in patients with stable coronary heart disease. The American journal of cardiology. vol 114. issue 2. 2014-08-26. PMID:24952926. |
given that the pathophysiology of depression is considered to involve disruption in brain serotonergic signaling, we investigated platelet response to serotonin stimulation in patients with stable coronary artery disease (cad). |
2014-08-26 |
2023-08-13 |
Not clear |
| Dan A Kim, Willie G McClure, Jordan B Neighoff, Dhananjay Vaidya, Marlene S William. Platelet response to serotonin in patients with stable coronary heart disease. The American journal of cardiology. vol 114. issue 2. 2014-08-26. PMID:24952926. |
our study sheds light on the in vitro response of platelet function to serotonin in patients with stable cad, which may further the mechanistic understanding of heart disease and depression. |
2014-08-26 |
2023-08-13 |
Not clear |
| Yun Ju Chae, Ji Hyun Jeon, Hong Joon Lee, In-Beom Kim, Jin-Sung Choi, Ki-Wug Sung, Sang June Hah. Escitalopram block of hERG potassium channels. Naunyn-Schmiedeberg's archives of pharmacology. vol 387. issue 1. 2014-08-25. PMID:24045971. |
escitalopram, a selective serotonin reuptake inhibitor, is the pharmacologically active s-enantiomer of the racemic mixture of rs-citalopram and is widely used in the treatment of depression. |
2014-08-25 |
2023-08-12 |
human |
| b' Katarzyna Kami\\xc5\\x84ska, Krystyna Go\\xc5\\x82embiowska, Zofia Rog\\xc3\\xb3\\xc5\\xb. Effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex. Pharmacological reports : PR. vol 65. issue 5. 2014-08-25. PMID:24399710.' |
several clinical reports have documented a beneficial effect of the addition of a low dose of risperidone to the ongoing treatment with antidepressants, in particular selective serotonin reuptake inhibitors, in the treatment of drug resistant depression. |
2014-08-25 |
2023-08-12 |
rat |
| Xian-Zhe Dong, Zhao-Liang Li, Xiao-Li Zheng, Li-Hua Mu, Gang-qiang Zhang, Ping Li. A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats. Journal of ethnopharmacology. vol 150. issue 3. 2014-08-22. PMID:24184266. |
previously, we have found that in a variety of animal models of depression (such as tail suspension model, model of chronic fatigue and forced swimming model) dz demonstrated significant antidepressant behavior and promoted the production of 5-hydroxytryptamine (5-ht). |
2014-08-22 |
2023-08-12 |
rat |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
the result showed that: contrased with the normal person group, the mean value of the six neurotransmitters in depression patients group are: (1) in the whole encephalic region of depression patients group the dopamine fall (p < 0.05), and in the double centralregions, right temporal region and right parietal region distinct fall (p < 0.01); (2) in the right temporal region of depression patients group the serotonin rise (p < 0.05); (3) in the right central region, left parietal region of depression patients group the acetylcholine fall (p < 0.05), left rear temporal region fall obviously (p < 0.01). |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
serotonin and dopamine, which are characterized by weak negative correlation in the right rear temporal region of ordinary person group, are characterized by strong negative correlation in the other encephalic regions and the whole encephalic (ordinary person group except the right rear temporal region: the range of [r] is [0.82, 0.92], p < 0.01)/(depression patients group:the range of [r] is [0.88, 0.94], p < 0.01); acetylcholine and norepinephrine, in the whole and various encephalic region are characterized by middle negative correlation(ordinary person group:the range of [r] is [0.39, 0.76], p < 0.01 or p < 0.05)/(depression patients group: the range of [ir] is [0.56, 0.64], p < 0.01); depression neurotransmitters and excited neurotransmitters are characterized by middle strong negative correlation (ordinary person group: the range of [r] is [0.57, 0.80], p < 0.01)/(depression patients group: the range of [r] is [0.68, 0.78], p < 0.01). |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
(2) the two neurotransmitters which are not antagonizing pairs of neurotransmitters, serotonin and excited neurotransmitters, or acetylcholine and depression neurotra-nsmitters, or dopamine and depression neurotransmitters in the various encephalic regions are characterized by weak negative correlation. |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
serotonin and excited neurotransmitters are characterizeed by weak negative correlation (ordinary person group: in the right central region, left parietal region, double front temporal regions, right rear temporal region, the range of [r] is [0.25, 0.50], p < 0.01 or p < 0.05)/(depression patients group: in the whole encephalic regions, double parietal regions, double occipital regions, right front temporal region, left central region, left frontal region, the range of [r] is [0.18, 0.37], p < 0.01 or p < 0.05); acetylcholine and depression, neurotransmitters are characterized by weak negative correlation (ordinary person group: in the double frontal regions, left parietal region, left front temporal region, right rear temporal region, the range of [r] is [0.31, 0.46], p < 0.01 or p < 0.05)/(depression patients group: in double rear temporal regions, right front temporal region, double occipital regions, left central region, the range of [r] is [0.20, 0.32] , p < 0.01 or p < 0.05); do-pamine and depression neurotransmitters are characterized by weak middle negative correlation (ordinary person group: in left parietal region, right central region, left frontal region, left occipital region, double front temporal regions, the range of [r] is [0.33, 0.68], p < 0.01 or p < 0.05)/(depression patients group: in the whole region and other various regions except the left frontal region, right central region, the range of irl is [0.21, 0.34], p < 0.01 or p < 0.05). |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
dopamine and acetylcholine are characterized by weak positive correlation (ordinary person group: in left frontal region, right parietal region, left front temporal region and left rear temporal region, the range of [r] is [0.37, 0.46], p < 0.01)/(depression patients group: in the whole region and the orther various regions except the double central regions, the range of [r] is [0.23, 0.5], p < 0.01 or p < 0.05); norepinephrine and serotonin are characterized by weak positive correlation (ordinary person group: in double front temporal regions, double rear temporal regions, right frontal region and left parietal region, the range of [r] is [0.34, 0.48], p < 0.01 or p < 0.05)/(depression patients group: in the whole and various regions, the range of [r] is [0.18, 0.42], p < 0.01). |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
(2) the percent of dopamine falling or including dopamine falling, or including dopamine falling and serotonin rising in depression patients group increases. |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
the percent of dopamine falling or including dopamine falling in the whole region, right frontal region, right central region increases (p < 0.01), such as dopamine decreasing, serotonin increasing dopamine decreasing, serotonin increasing acetylcholine decreasing dopamine decreasing, dopamine decreasing norepinephrine increasing depression neurotransmitters decreasing, serotonin increasing acetylcholine decreasing dopamine decreasing neurotransmitters increasing and so on. |
2014-08-21 |
2023-08-13 |
Not clear |
| Ming Chi, Xue-Mei Qing, Yan-Shu Pan, Feng-Quan Xu, Chao Liu, Cheng Zhang, Zhen-Hua X. [Preliminary research on multi-neurotransmitters' change regulation in 120 depression patients' brains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 8. 2014-08-21. PMID:25039193. |
the percent of acetylcholine falling, or including acetylcholine falling in the right temporal region, double central regions increases (p < 0.05 or p < 0.01), such as acetylcholine decreasing, acetylcholine decreasing neurotransmitters increaseng, acetylcholine decreasing neurotransmitters increasing depression neurotransmitters decreasing, serotonin increasing acetylcholine decreasing dopamine decreasing neurotransmitters increasing and so on. |
2014-08-21 |
2023-08-13 |
Not clear |
| Yingtong Zeng, Xingqian Xie, Jingjing Duan, Ting Zhou, Ye Zhang, Min Yang, Feng X. Perturbation of mitiglinide metabolism by chronic unpredicted mild stress in rats. Scientific reports. vol 4. 2014-08-18. PMID:24445843. |
open-field test and 5-ht levels were assayed to evaluate the depression. |
2014-08-18 |
2023-08-12 |
rat |