| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Oved, A Morag, M Pasmanik-Chor, M Rehavi, N Shomron, D Gurwit. Genome-wide expression profiling of human lymphoblastoid cell lines implicates integrin beta-3 in the mode of action of antidepressants. Translational psychiatry. vol 3. 2014-06-05. PMID:24129413. |
our observations suggest that ssris may relieve depression primarily by promoting neuronal synaptogenesis/neurogenesis rather than by modulating serotonin neurotransmission per se. |
2014-06-05 |
2023-08-12 |
human |
| Andrew C Parrot. The potential dangers of using MDMA for psychotherapy. Journal of psychoactive drugs. vol 46. issue 1. 2014-06-05. PMID:24830184. |
mdma administration is followed by a period of neurochemical recovery, when low serotonin levels are often accompanied by lethargy and depression. |
2014-06-05 |
2023-08-13 |
Not clear |
| Adele Stewart, Biswanath Maity, Amanda M Wunsch, Fantao Meng, Qi Wu, John A Wemmie, Rory A Fishe. Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 4. 2014-06-02. PMID:24421401. |
regulator of g-protein signaling 6 (rgs6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-ht(1a) receptor-adenylyl cyclase axis. |
2014-06-02 |
2023-08-12 |
mouse |
| Carmen Frías-Domínguez, Julieta Garduño, Salvador Hernández, René Drucker-Colin, Stefan Mihailesc. Flattening plasma corticosterone levels increases the prevalence of serotonergic dorsal raphe neurons inhibitory responses to nicotine in adrenalectomised rats. Brain research bulletin. vol 98. 2014-05-30. PMID:23872451. |
nicotine improves mood in patients with major depression and in experimentally depressed animals by increasing brain serotonin (5-ht), noradrenaline and dopamine levels. |
2014-05-30 |
2023-08-12 |
rat |
| C D Rethorst, M S Toups, T L Greer, P A Nakonezny, T J Carmody, B D Grannemann, R M Huebinger, R C Barber, M H Trived. Pro-inflammatory cytokines as predictors of antidepressant effects of exercise in major depressive disorder. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:22925832. |
in the treatment with exercise augmentation for depression (tread) study, participants who were partial responders to a selective serotonin reuptake inhibitor were randomized to receive one of two doses of exercise: 16 kilocalories per kilogram of body weight per week (kkw), or 4 kkw for 12 weeks. |
2014-05-29 |
2023-08-12 |
human |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
cognitive impairments are common in depression and involve dysfunctional serotonin neurotransmission. |
2014-05-29 |
2023-08-12 |
mouse |
| Evelien Gellynck, Karen Heyninck, Kjetil W Andressen, Guy Haegeman, Finn Olav Levy, Peter Vanhoenacker, Kathleen Van Craenenbroec. The serotonin 5-HT7 receptors: two decades of research. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:24042216. |
serotonin is involved in numerous functions in the human body including the control of appetite, sleep, memory and learning, temperature regulation, mood, behavior, cardiovascular function, muscle contraction, endocrine regulation, and depression. |
2014-05-27 |
2023-08-12 |
human |
| Jiang-Yuan Hu, Samuel Schache. Persistent long-term facilitation at an identified synapse becomes labile with activation of short-term heterosynaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 14. 2014-05-22. PMID:24695698. |
short-term heterosynaptic plasticity induced by 5-ht (facilitation) or the neuropeptide fmrfa (depression) and short-term homosynaptic plasticity induced by tetanus [post-tetanic potentiation (ptp)] or low-frequency stimulation [homosynaptic depression (hsd)] of the sensory neuron were expressed in both control synapses and synapses expressing p-ltf in the absence or presence of protein synthesis inhibitors. |
2014-05-22 |
2023-08-13 |
aplysia |
| Annette M La Greca, Betty S Lai, Jutta Joormann, Beth B Auslander, Mary A Shor. Children's risk and resilience following a natural disaster: genetic vulnerability, posttraumatic stress, and depression. Journal of affective disorders. vol 151. issue 3. 2014-05-21. PMID:24035489. |
we examined children's risk and resilience following a natural disaster, evaluating the role of stress, social support, and two genetic markers: the short allele of the serotonin transporter gene (5-httlpr), and the met allele of the brain-derived neurotrophic factor (bdnf).under high levels of hurricane exposure or hurricane-related stressors, we expected children displaying the markers would report greater symptoms of posttraumatic stress disorder (ptsd) and depression than children without these markers. |
2014-05-21 |
2023-08-12 |
Not clear |
| Ine Rayen, Harry W M Steinbusch, Thierry D Charlier, Jodi L Pawlusk. Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring. Psychoneuroendocrinology. vol 38. issue 9. 2014-05-14. PMID:23399049. |
while selective serotonin reuptake inhibitor (ssri) medications are the drug of choice for treatment of maternal depression, the combined effect of maternal depression and perinatal ssri exposure on offspring development is poorly investigated. |
2014-05-14 |
2023-08-12 |
rat |
| Ya-Chin Yang, Chun-Chang Hu, Chen-Syuan Huang, Pei-Yu Cho. Thalamic synaptic transmission of sensory information modulated by synergistic interaction of adenosine and serotonin. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24147740. |
adenosine plus serotonin results in robust synergistic inhibition of synaptic strength and dramatic transformation of short-term synaptic depression to facilitation. |
2014-05-14 |
2023-08-12 |
Not clear |
| Dan Liu, Hong-Mei Qiu, Hui-Zhi Fei, Xiao-Ya Hu, Hai-Jian Xia, Li-Jia Wang, Li-Juan Qin, Xin-Hui Jiang, Qi-Xin Zho. Histone acetylation and expression of mono-aminergic transmitters synthetases involved in CUS-induced depressive rats. Experimental biology and medicine (Maywood, N.J.). vol 239. issue 3. 2014-05-14. PMID:24495952. |
the aim of the present study was to investigate whether it was associated with epigenetic histone modification and gene expression of enzymes responsible for the biosynthesis of norepinephrine and serotonin in rat depression model induced by chronic unpredictable stress (cus). |
2014-05-14 |
2023-08-12 |
rat |
| T J Stamm, J Stingl, K Wiethoff, R Ricken, A Heinz, M Bauer, G O'Malley, M Adl. Depression with psychotic features is influenced by the polymorphism of the serotonin transporter gene. Journal of affective disorders. vol 151. issue 2. 2014-05-13. PMID:23948632. |
depression with psychotic features is influenced by the polymorphism of the serotonin transporter gene. |
2014-05-13 |
2023-08-12 |
Not clear |
| T J Stamm, J Stingl, K Wiethoff, R Ricken, A Heinz, M Bauer, G O'Malley, M Adl. Depression with psychotic features is influenced by the polymorphism of the serotonin transporter gene. Journal of affective disorders. vol 151. issue 2. 2014-05-13. PMID:23948632. |
in the course of the search for discriminating factors we tested the hypothesis that the serotonin transporter gene (5-httlpr) may interact with the manifestation of psychotic symptoms in acute depression. |
2014-05-13 |
2023-08-12 |
Not clear |
| Mohammad M Herzallah, Ahmed A Moustafa, Joman Y Natsheh, Omar A Danoun, Jessica R Simon, Yasin I Tayem, Mahmud A Sehwail, Ivona Amleh, Issam Bannoura, Georgios Petrides, Catherine E Myers, Mark A Gluc. Depression impairs learning, whereas the selective serotonin reuptake inhibitor, paroxetine, impairs generalization in patients with major depressive disorder. Journal of affective disorders. vol 151. issue 2. 2014-05-13. PMID:23953023. |
depression impairs learning, whereas the selective serotonin reuptake inhibitor, paroxetine, impairs generalization in patients with major depressive disorder. |
2014-05-13 |
2023-08-12 |
Not clear |
| Gen Shinozaki, Magdalena Romanowicz, David A Mrazek, Simon Kun. HTR2A gene-child abuse interaction and association with a history of suicide attempt among Caucasian depressed psychiatric inpatients. Journal of affective disorders. vol 150. issue 3. 2014-05-12. PMID:23759279. |
the serotonin transporter gene polymorphism (5httlpr) has been associated with vulnerability for depression after exposure to stressful life event as well as with difference in treatment response to ssri. |
2014-05-12 |
2023-08-12 |
Not clear |
| Takahiro Kato, Seiji Kajiyama, Hiroshi Hamada, Masashi Kawamot. Long-term administration of fluvoxamine attenuates neuropathic pain and involvement of spinal serotonin receptors in diabetic model rats. Hiroshima journal of medical sciences. vol 62. issue 4. 2014-05-06. PMID:24597211. |
fluvoxamine, a class of selective serotonin reuptake inhibitors (ssris), is widely used to treat depression. |
2014-05-06 |
2023-08-12 |
rat |
| Giorgi Batsikadze, Walter Paulus, Min-Fang Kuo, Michael A Nitsch. Effect of serotonin on paired associative stimulation-induced plasticity in the human motor cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 11. 2014-05-05. PMID:23680943. |
these results show that serotonin modulates pas-induced neuroplasticity by shifting it into the direction of facilitation, which might help to explain mechanism of positive therapeutic effects of serotonin in learning and medical conditions characterized by enhanced inhibitory or reduced facilitatory plasticity, including depression and stroke. |
2014-05-05 |
2023-08-12 |
human |
| Jay D Amsterdam, Andrew B Newberg, Cory F Newman, Justine Shults, Nancy Wintering, Irene Soelle. Change over time in brain serotonin transporter binding in major depression: effects of therapy measured with [(123) I]-ADAM SPECT. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 23. issue 4. 2014-05-05. PMID:23751132. |
change over time in brain serotonin transporter binding in major depression: effects of therapy measured with [(123) i]-adam spect. |
2014-05-05 |
2023-08-12 |
human |
| Jay D Amsterdam, Andrew B Newberg, Cory F Newman, Justine Shults, Nancy Wintering, Irene Soelle. Change over time in brain serotonin transporter binding in major depression: effects of therapy measured with [(123) I]-ADAM SPECT. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 23. issue 4. 2014-05-05. PMID:23751132. |
several studies have reported low brain serotonin transporter (sert) binding in individuals with major depression. |
2014-05-05 |
2023-08-12 |
human |