| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher Barkus, Samantha J Line, Anna Huber, Liliana Capitao, Joao Lima, Katie Jennings, John Lowry, Trevor Sharp, David M Bannerman, Stephen B McHug. Variation in serotonin transporter expression modulates fear-evoked hemodynamic responses and theta-frequency neuronal oscillations in the amygdala. Biological psychiatry. vol 75. issue 11. 2014-12-16. PMID:24120093. |
gene association studies detect an influence of natural variation in the 5-hydroxytryptamine transporter (5-htt) gene on multiple aspects of individuality in brain function, ranging from personality traits through to susceptibility to psychiatric disorders such as anxiety and depression. |
2014-12-16 |
2023-08-12 |
human |
| Eun-Kyung Hwang, Jun-mo Chun. 5HT(1B) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula. Neuropharmacology. vol 81. 2014-12-15. PMID:24508708. |
5ht(1b) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula. |
2014-12-15 |
2023-08-12 |
rat |
| Eun-Kyung Hwang, Jun-mo Chun. 5HT(1B) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula. Neuropharmacology. vol 81. 2014-12-15. PMID:24508708. |
the present study provides the first evidence that glutamatergic transmission of lhb synapses is inhibited by activation of the 5ht(1b) receptor at the pre-synapse in both acute depression (5ht-ad) and long-term depression (5ht-ltd). |
2014-12-15 |
2023-08-12 |
rat |
| Deepali Gupta, Yeshwant Kurhe, Mahesh Radhakrishna. Antidepressant effects of insulin in streptozotocin induced diabetic mice: Modulation of brain serotonin system. Physiology & behavior. vol 129. 2014-12-15. PMID:24582678. |
collectively, the data indicate that insulin exhibits antidepressant effects in depression associated with stz induced diabetes in mice through the elevation of the brain serotonin levels. |
2014-12-15 |
2023-08-12 |
mouse |
| Melissa DeFilippis, Karen Dineen Wagne. Management of treatment-resistant depression in children and adolescents. Paediatric drugs. vol 16. issue 5. 2014-12-14. PMID:25200567. |
selective serotonin reuptake inhibitors (ssris) are the first-line treatment for depression in children and adolescents. |
2014-12-14 |
2023-08-13 |
Not clear |
| Abdulla A-B Badaw. Pellagra and alcoholism: a biochemical perspective. Alcohol and alcoholism (Oxford, Oxfordshire). vol 49. issue 3. 2014-12-10. PMID:24627570. |
depression in pellagra may be due to a serotonin deficiency caused by decreased trp availability to the brain. |
2014-12-10 |
2023-08-12 |
Not clear |
| Robert C Culverhouse, Lucy Bowes, Naomi Breslau, John I Nurnberger, Margit Burmeister, David M Fergusson, Marcus Munafò, Nancy L Saccone, Laura J Bieru. Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC psychiatry. vol 13. 2014-12-05. PMID:24219410. |
debate is ongoing about what role, if any, variation in the serotonin transporter linked polymorphic region (5-httlpr) plays in depression. |
2014-12-05 |
2023-08-12 |
Not clear |
| Donatella Marazziti, Hagop S Akiskal, Mieko Udo, Michela Picchetti, Stefano Baroni, Gabriele Massimetti, Francesco Albanese, Liliana Dell'Oss. Dimorphic changes of some features of loving relationships during long-term use of antidepressants in depressed outpatients. Journal of affective disorders. vol 166. 2014-12-05. PMID:25012424. |
the present study aimed at investigating the possible changes of some features of loving relationships during long-term treatment of depression with both selective serotonin reuptake inhibitors (ssris) and tricyclics (tcas), by means of a specifically designed test, the so-called "sex, attachment, love" (salt) questionnaire. |
2014-12-05 |
2023-08-13 |
Not clear |
| Man Tang, Tao He, Xiao Sun, Qing-Yan Meng, Yao Diao, Jie-Yu Lei, Xiao-Jing He, Lei Chen, Xiu-Bo Sang, Shulei Zha. Subregion-specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24436084. |
subregion-specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression. |
2014-12-03 |
2023-08-12 |
mouse |
| Man Tang, Tao He, Xiao Sun, Qing-Yan Meng, Yao Diao, Jie-Yu Lei, Xiao-Jing He, Lei Chen, Xiu-Bo Sang, Shulei Zha. Subregion-specific decreases in hippocampal serotonin transporter protein expression and function associated with endophenotypes of depression. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24436084. |
cort treatment induced anhedonia and behavioral despair, two core endophenotypes of clinical depression; 5-htt protein expression levels and synaptosomal 5-ht uptake were both decreased in a subregion-specific manner, with the greatest decrease observed in the dg, a moderate decrease in the ca3, and the ca1 showed no apparent change. |
2014-12-03 |
2023-08-12 |
mouse |
| Kazuki Terada, Nobuo Izumo, Biora Suzuki, Yoshiharu Karube, Tomomi Morikawa, Yukiko Ishibashi, Toshiki Kameyama, Koji Chiba, Noriko Sasaki, Keiko Iwata, Hideo Matsuzaki, Takayuki Manab. Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades. Neurochemistry international. vol 69. 2014-12-03. PMID:24582626. |
selective serotonin reuptake inhibitors (ssris) effectively treat depression. |
2014-12-03 |
2023-08-12 |
mouse |
| Brett Q Ford, Iris B Mauss, Allison S Troy, Andrew Smolen, Benjamin Hanki. Emotion regulation moderates the risk associated with the 5-HTT gene and stress in children. Emotion (Washington, D.C.). vol 14. issue 5. 2014-12-01. PMID:24866526. |
carrying a short allele in the serotonin transporter polymorphism (5-httlpr) while experiencing stressful environments is linked to elevated risk for depression. |
2014-12-01 |
2023-08-13 |
Not clear |
| H Welper, A Aller, V Guttenthaler, S Höfels, L Lennertz, U Pfeiffer, S G Schwab, A Zobe. [Serotonin transporter gene and stress reactivity in unipolar depression. Role of the HPA system as endophenotype of the SLC6A4 gene]. Der Nervenarzt. vol 85. issue 3. 2014-11-18. PMID:23325311. |
[serotonin transporter gene and stress reactivity in unipolar depression. |
2014-11-18 |
2023-08-12 |
Not clear |
| H Welper, A Aller, V Guttenthaler, S Höfels, L Lennertz, U Pfeiffer, S G Schwab, A Zobe. [Serotonin transporter gene and stress reactivity in unipolar depression. Role of the HPA system as endophenotype of the SLC6A4 gene]. Der Nervenarzt. vol 85. issue 3. 2014-11-18. PMID:23325311. |
a length polymorphism in the promoter region of the serotonin transporter gene (5-httlpr) is associated with both depression and hypothalamic-pituitary-adrenal (hpa) system activity. |
2014-11-18 |
2023-08-12 |
Not clear |
| Allison C Nugent, Paul J Carlson, Earle E Bain, William Eckelman, Peter Herscovitch, Husseini Manji, Carlos A Zarate, Wayne C Drevet. Mood stabilizer treatment increases serotonin type 1A receptor binding in bipolar depression. Journal of psychopharmacology (Oxford, England). vol 27. issue 10. 2014-11-15. PMID:23926239. |
mood stabilizer treatment increases serotonin type 1a receptor binding in bipolar depression. |
2014-11-15 |
2023-08-12 |
human |
| Nathalie Bock, Emre Koc, Hannah Alter, Veit Roessner, Andreas Becker, Aribert Rothenberger, Till Manzk. Chronic fluoxetine treatment changes S100B expression during postnatal rat brain development. Journal of child and adolescent psychopharmacology. vol 23. issue 7. 2014-11-14. PMID:24024533. |
fluoxetine, a selective serotonin reuptake inhibitor, is approved for treatment of childhood depression. |
2014-11-14 |
2023-08-12 |
rat |
| Sui-Cheung Man, Ben H B Hung, Roger M K Ng, Xiao-Chun Yu, Hobby Cheung, Mandy P M Fung, Leonard S W Li, Kwok-Pui Leung, Kei-Pui Leung, Kevin W Y Tsang, Eric Ziea, Vivian T Wong, Zhang-Jin Zhan. A pilot controlled trial of a combination of dense cranial electroacupuncture stimulation and body acupuncture for post-stroke depression. BMC complementary and alternative medicine. vol 14. 2014-11-14. PMID:25038733. |
the purpose of the present study was to further evaluate the effectiveness of dceas combined with body acupuncture and selective serotonin reuptake inhibitors (ssris) in patients with post-stroke depression (psd). |
2014-11-14 |
2023-08-13 |
Not clear |
| Márcia Calheiros Chaves Silva, Luis Rafael Leite Sampaio, Dayane Pessoa de Araújo, Paulo Victor Pontes Araújo, Aline Santos Monte, Francisca Taciana Sousa Rodrigues, David John Woods, Francisca Cléa Florenço de Sousa, Marta Maria França Fonteles, Silvânia Maria Mendes Vasconcelo. Central effects of lipoic acid associated with paroxetine in mice. American journal of therapeutics. vol 21. issue 2. 2014-11-06. PMID:23797756. |
antidepressants, including selective serotonin reuptake inhibitors, are commonly prescribed for the treatment of affective disorders such as anxiety and depression. |
2014-11-06 |
2023-08-12 |
mouse |
| Julian Macovean. Serotonergic modulation of reward and punishment: evidence from pharmacological fMRI studies. Brain research. vol 1556. 2014-11-06. PMID:24508910. |
the new findings may have implications in understanding psychiatric disorders such as major depression which is characterized by abnormal serotonergic function and reward-related processing and may also provide a neural correlated for the emotional blunting observed in the clinical treatment of psychiatric disorders with selective serotonin reuptake inhibitors. |
2014-11-06 |
2023-08-12 |
human |
| Rick H A van der Doelen, Francesca Calabrese, Gianluigi Guidotti, Bram Geenen, Marco A Riva, Tamás Kozicz, Judith R Homber. Early life stress and serotonin transporter gene variation interact to affect the transcription of the glucocorticoid and mineralocorticoid receptors, and the co-chaperone FKBP5, in the adult rat brain. Frontiers in behavioral neuroscience. vol 8. 2014-10-29. PMID:25352794. |
the short allelic variant of the serotonin transporter (5-htt) promoter-linked polymorphic region (5-httlpr) has been associated with the etiology of major depression by interaction with early life stress (els). |
2014-10-29 |
2023-08-13 |
rat |