| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Wankerl, R Miller, C Kirschbaum, J Hennig, T Stalder, N Alexande. Effects of genetic and early environmental risk factors for depression on serotonin transporter expression and methylation profiles. Translational psychiatry. vol 4. 2015-03-06. PMID:24937096. |
the serotonin transporter (sert) gene-linked polymorphic region (5-httlpr) has been implicated in moderating the link between life stress and depression. |
2015-03-06 |
2023-08-13 |
human |
| R H A van der Doelen, W Deschamps, C D'Annibale, D Peeters, R A Wevers, D Zelena, J R Homberg, T Kozic. Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis. Translational psychiatry. vol 4. 2015-03-06. PMID:25004389. |
the short allelic variant of the serotonin transporter (5-htt) promoter-linked polymorphic region (5-httlpr) has been associated with the etiology of major depression by interaction with early life stress (els). |
2015-03-06 |
2023-08-13 |
rat |
| I-H Baek, B-Y Lee, W Kang, K-I Kwo. Pharmacokinetic analysis of two different doses of duloxetine following oral administration in dogs. Drug research. vol 63. issue 8. 2015-03-02. PMID:23599035. |
duloxetine is a potent and balanced dual inhibitor of serotonin and norepinephrine reuptake that is being investigated for the treatment of depression and urinary incontinence. |
2015-03-02 |
2023-08-12 |
Not clear |
| Ryan Bogdan, Arpana Agrawal, Michael S Gaffrey, Rebecca Tillman, Joan L Lub. Serotonin transporter-linked polymorphic region (5-HTTLPR) genotype and stressful life events interact to predict preschool-onset depression: a replication and developmental extension. Journal of child psychology and psychiatry, and allied disciplines. vol 55. issue 5. 2015-03-02. PMID:24117502. |
serotonin transporter-linked polymorphic region (5-httlpr) genotype and stressful life events interact to predict preschool-onset depression: a replication and developmental extension. |
2015-03-02 |
2023-08-12 |
Not clear |
| Amy L Non, Alexandra M Binder, Laura D Kubzansky, Karin B Michel. Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy. Epigenetics. vol 9. issue 7. 2015-03-01. PMID:24751725. |
in this study we investigated patterns of genome-wide dna methylation using the illumina infinium human methylation450 beadchip in the umbilical cord blood of neonates exposed to non-medicated maternal depression or anxiety (n = 13), or selective serotonin reuptake inhibitors (ssris) during pregnancy (n = 22), relative to unexposed neonates (n = 23). |
2015-03-01 |
2023-08-13 |
human |
| Andreas Hahn, Daniela Haeusler, Christoph Kraus, Anna S Höflich, Georg S Kranz, Pia Baldinger, Markus Savli, Markus Mitterhauser, Wolfgang Wadsak, Georgios Karanikas, Siegfried Kasper, Rupert Lanzenberge. Attenuated serotonin transporter association between dorsal raphe and ventral striatum in major depression. Human brain mapping. vol 35. issue 8. 2015-02-27. PMID:24443158. |
attenuated serotonin transporter association between dorsal raphe and ventral striatum in major depression. |
2015-02-27 |
2023-08-12 |
human |
| S Skurtveit, R Selmer, C Roth, S Hernandez-Diaz, M Handa. Prenatal exposure to antidepressants and language competence at age three: results from a large population-based pregnancy cohort in Norway. BJOG : an international journal of obstetrics and gynaecology. vol 121. issue 13. 2015-02-26. PMID:24726047. |
to examine the association between maternal use of selective serotonin reuptake inhibitors (ssri) in pregnancy and language competence in their children at age three taking into account maternal symptoms of anxiety and depression. |
2015-02-26 |
2023-08-13 |
Not clear |
| Leslie Citrom. Treatment of bipolar depression: making sensible decisions. CNS spectrums. vol 19 Suppl 1. 2015-02-26. PMID:25407667. |
none of the classic antidepressants, serotonin specific reuptake inhibitors, or serotonin-norepinephrine reuptake inhibitors have ever received regulatory approval as monotherapies for the treatment of bipolar depression. |
2015-02-26 |
2023-08-13 |
Not clear |
| Francesc Artiga. Deep brain stimulation in major depression: plastic changes of 5-hydroxytryptamine neurons. Biological psychiatry. vol 76. issue 3. 2015-02-23. PMID:25012045. |
deep brain stimulation in major depression: plastic changes of 5-hydroxytryptamine neurons. |
2015-02-23 |
2023-08-13 |
Not clear |
| William R Lovallo, Mary-Anne Enoch, Eldad Yechiam, David C Glahn, Ashley Acheson, Kristen H Sorocco, Colin A Hodgkinson, Bojeong Kim, Andrew J Cohoon, Andrea S Vincent, David Goldma. Differential impact of serotonin transporter activity on temperament and behavior in persons with a family history of alcoholism in the Oklahoma Family Health Patterns Project. Alcoholism, clinical and experimental research. vol 38. issue 6. 2015-02-12. PMID:24796636. |
central serotonergic (5-ht) function is implicated in pathways to alcohol dependence, including dysphoria manifested by symptoms of anxiety and depression. |
2015-02-12 |
2023-08-13 |
Not clear |
| Kyung-Bok Lee, Eun Cho, Young-Sook Kan. Changes in 5-hydroxytryptamine and cortisol plasma levels in menopausal women after inhalation of clary sage oil. Phytotherapy research : PTR. vol 28. issue 11. 2015-02-10. PMID:24802524. |
the different change rate of 5-ht concentration between normal and depression tendency groups was variable according to the depression measurement inventory. |
2015-02-10 |
2023-08-13 |
human |
| Kyung-Bok Lee, Eun Cho, Young-Sook Kan. Changes in 5-hydroxytryptamine and cortisol plasma levels in menopausal women after inhalation of clary sage oil. Phytotherapy research : PTR. vol 28. issue 11. 2015-02-10. PMID:24802524. |
when using kbdi-i and kbdi-ii, 5-ht increased by 341% and 828% for the normal group and 484% and 257% for the depression tendency group, respectively. |
2015-02-10 |
2023-08-13 |
human |
| Arndis Simonsen, Jørgen Scheel-Krüger, Mads Jensen, Andreas Roepstorff, Arne Møller, Chris D Frith, Daniel Campbell-Meiklejoh. Serotoninergic effects on judgments and social learning of trustworthiness. Psychopharmacology. vol 231. issue 14. 2015-02-09. PMID:24464530. |
certain disorders, such as depression and anxiety, to which serotonin dysfunction is historically associated, are also associated with lower assessments of other people's trustworthiness. |
2015-02-09 |
2023-08-12 |
Not clear |
| Mariana Postal, Simone Appenzelle. The importance of cytokines and autoantibodies in depression. Autoimmunity reviews. vol 14. issue 1. 2015-02-09. PMID:25242344. |
the association between decreased serotonin levels and excessive glutamatergic activity forms the first biochemical basis for cytokine-induced depression. |
2015-02-09 |
2023-08-13 |
Not clear |
| Mariana Postal, Simone Appenzelle. The importance of cytokines and autoantibodies in depression. Autoimmunity reviews. vol 14. issue 1. 2015-02-09. PMID:25242344. |
tumor necrosis factor alpha (tnf-α) may underlie the mechanism of depression by an activation of the hypothalamo-pituitary-adrenocortical (hpa) axis, an activation of neuronal serotonin transporters and the stimulation of the indoleamine 2,3-dioxygenase which leads to tryptophan depletion. |
2015-02-09 |
2023-08-13 |
Not clear |
| A M Yohannes, G S Alexopoulo. Pharmacological treatment of depression in older patients with chronic obstructive pulmonary disease: impact on the course of the disease and health outcomes. Drugs & aging. vol 31. issue 7. 2015-02-04. PMID:24902934. |
both selective serotonin reuptake inhibitor (ssri) and tricyclic antidepressant (tca) studies conducted in depressed copd patients have been significantly limited by methodological weaknesses including small sample size, sample heterogeneity and variability in the scales used to diagnose and monitor the treatment of depression. |
2015-02-04 |
2023-08-13 |
Not clear |
| Gunnar Sørensen, Henriette Husum, Lise T Brennum, Christoffer Bundgaard, Liliana C P Montezinho, Arne Mørk, Gitta Wörtwein, David P D Woldby. Addiction-related effects of DOV 216,303 and cocaine: A comparative study in the mouse. Basic & clinical pharmacology & toxicology. vol 114. issue 6. 2015-02-02. PMID:24314270. |
dov 216,303, an inhibitor of serotonin, noradrenaline and dopamine reuptake, belongs to a new line of drugs called 'triple reuptake inhibitors' that have been proposed for treatment of depression. |
2015-02-02 |
2023-08-12 |
mouse |
| Paul R Albert, Laura M Fior. Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity. Current pharmaceutical design. vol 20. issue 23. 2015-01-30. PMID:24180393. |
the etiology of major depression remains unclear, but reduced activity of the serotonin (5-ht) system remains implicated and treatments that increase 5-ht neurotransmission can ameliorate depressive symptoms. |
2015-01-30 |
2023-08-12 |
Not clear |
| Analia Bortolozzi, Pau Celada, Francesc Artiga. Novel therapeutic strategies in major depression: focus on RNAi and ketamine. Current pharmaceutical design. vol 20. issue 23. 2015-01-30. PMID:24180396. |
the pharmacological treatment of major depression is mainly based on drugs inhibiting serotonin (5-hydroxytryptamine, 5-ht) and/or noradrenaline (na) reuptake. |
2015-01-30 |
2023-08-12 |
Not clear |
| Akiko Mori, Kazuhiro Yamaya, Yoshio Nitta, Seijiro Yoshid. [Coronary artery spasm induced by neuroleptic malignant syndrome during off-pump coronary artery bypass grafting; report of a case]. Kyobu geka. The Japanese journal of thoracic surgery. vol 67. issue 3. 2015-01-29. PMID:24743539. |
she had been orally receiving selective serotonin reuptake inhibitor( ssri) for the treatment of depression. |
2015-01-29 |
2023-08-13 |
Not clear |