| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hai-Yin Jiang, Min Deng, Yong-Hua Zhang, Hua-Zhong Chen, Qian Chen, Bing Rua. Specific serotonin reuptake inhibitors prevent interferon-α-induced depression in patients with hepatitis C: a meta-analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. vol 12. issue 9. 2015-05-27. PMID:23648373. |
specific serotonin reuptake inhibitors (ssris) can be used to treat depression, but it is not clear whether they can prevent depression in patients receiving ifn therapy for chronic hcv infection. |
2015-05-27 |
2023-08-12 |
Not clear |
| Masayoshi Mori, Yusuke Murata, Asami Matsuo, Tomoyo Takemoto, Kazunori Min. Chronic Treatment with the 5-HT1A Receptor Partial Agonist Tandospirone Increases Hippocampal Neurogenesis. Neurology and therapy. vol 3. issue 1. 2015-05-22. PMID:26000223. |
a large-scale clinical trial, the sequence trial alternatives to relieve depression (star*d) study, concluded that about one-third of the studied patients with major depressive disorder remitted during the initial treatment with selective serotonin reuptake inhibitors and that approximately half of the remitted subjects relapsed over a 1-year follow-up. |
2015-05-22 |
2023-08-13 |
human |
| Seung-Hwan Lee, Young-Cheon Park, Sunkyung Yoon, Jeong-In Kim, Sang Woo Hah. Clinical implications of loudness dependence of auditory evoked potentials in patients with atypical depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 54. 2015-05-12. PMID:24865151. |
the loudness dependence of auditory evoked potentials (ldaep) has been proposed as a useful biomarker of serotonin activity, and the ldaep value is low in patients with melancholic depression. |
2015-05-12 |
2023-08-13 |
Not clear |
| Melanie Vincent, Guangping Gao, Lauren Jacobso. Comparison of the efficacy of five adeno-associated virus vectors for transducing dorsal raphé nucleus cells in the mouse. Journal of neuroscience methods. vol 235. 2015-05-12. PMID:25046366. |
the dorsal raphé nucleus (drn) and median raphé provides the majority of serotonin to forebrain regions and are implicated in the pathology and treatment of depression and anxiety. |
2015-05-12 |
2023-08-13 |
mouse |
| Katsuhiko Fukud. Etiological classification of depression based on the enzymes of tryptophan metabolism. BMC psychiatry. vol 14. 2015-05-12. PMID:25540092. |
from recent therapeutic observations, both the serotonin (5-ht) and kynurenine pathways of tryptophan metabolism may be of particular importance to improved understanding of depression. |
2015-05-12 |
2023-08-13 |
Not clear |
| Heiko Graf, Martin Walter, Coraline D Metzger, Birgit Able. Antidepressant-related sexual dysfunction - perspectives from neuroimaging. Pharmacology, biochemistry, and behavior. vol 121. 2015-05-11. PMID:24333547. |
sexual dysfunction is not only a common symptom in major depression but also a frequent side-effect of antidepressant medication, mainly of the selective serotonin reuptake-inhibitors (ssri) that are often prescribed as a first line treatment option. |
2015-05-11 |
2023-08-12 |
Not clear |
| D Schijven, V C Sousa, J Roelofs, B Olivier, J D A Olivie. Serotonin 1A receptors and sexual behavior in a genetic model of depression. Pharmacology, biochemistry, and behavior. vol 121. 2015-05-11. PMID:24345571. |
serotonin 1a receptors and sexual behavior in a genetic model of depression. |
2015-05-11 |
2023-08-12 |
rat |
| Chaitali Ghosh, Mohammad Hossain, Addison Spriggs, Arnab Ghosh, Gerald A Grant, Nicola Marchi, Emilio Perucca, Damir Janigr. Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. Epilepsia. vol 56. issue 3. 2015-05-11. PMID:25656284. |
antiepileptic drugs such as carbamazepine (cbz) and selective serotonin reuptake inhibitors such as sertraline (srt) are commonly co-prescribed to patients with epilepsy and comorbid depression. |
2015-05-11 |
2023-08-13 |
Not clear |
| Young-Pyo Hong, Hyo-Chul Lee, Hyun-Tae Ki. Treadmill exercise after social isolation increases the levels of NGF, BDNF, and synapsin I to induce survival of neurons in the hippocampus, and improves depression-like behavior. Journal of exercise nutrition & biochemistry. vol 19. issue 1. 2015-05-11. PMID:25960950. |
additionally, we examined the effects of exercise on the number of serotonin (5-ht)- and tryptophan hydroxylase (tph)-positive cells in the raphe nuclei and on depression behaviors induced by social isolation. |
2015-05-11 |
2023-08-13 |
rat |
| Zhou Xiufang, Yan Li, Zhenhua Zhou, Shuaiguo Pa. [Clinical observasion of acupuncture in patients with depression and its impact on serum 5-HT]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 35. issue 2. 2015-05-08. PMID:25854015. |
[clinical observasion of acupuncture in patients with depression and its impact on serum 5-ht]. |
2015-05-08 |
2023-08-13 |
Not clear |
| Zhou Xiufang, Yan Li, Zhenhua Zhou, Shuaiguo Pa. [Clinical observasion of acupuncture in patients with depression and its impact on serum 5-HT]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 35. issue 2. 2015-05-08. PMID:25854015. |
to observe the clinical effect of acupuncture for depression and to discuss its impact on the content of 5-ht in patients with depression. |
2015-05-08 |
2023-08-13 |
Not clear |
| Jyotishman Pathak, Gyorgy Simon, Dingcheng Li, Joanna M Biernacka, Gregory J Jenkins, Christopher G Chute, Daniel K Hall-Flavin, Richard M Weinshilbou. Detecting Associations between Major Depressive Disorder Treatment and Essential Hypertension using Electronic Health Records. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. vol 2014. 2015-05-08. PMID:25954583. |
in this observational study, we investigate the correlation between depression and hypertension on a cohort of patients treated for major depressive disorder using selective serotonin reuptake inhibitors (ssris) and assess the effect of depression treatment on the diagnoses and treatment for essential hypertension. |
2015-05-08 |
2023-08-13 |
Not clear |
| Benjamin D Sachs, Jason R Ni, Marc G Caro. Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 8. 2015-05-01. PMID:25675490. |
brain serotonin (5-ht) deficiency and exposure to psychosocial stress have both been implicated in the etiology of depression and anxiety disorders, but whether 5-ht deficiency influences susceptibility to depression- and anxiety-like phenotypes induced by psychosocial stress has not been formally established. |
2015-05-01 |
2023-08-13 |
mouse |
| Jill D Waring, Amit Etkin, Joachim F Hallmayer, Ruth O'Har. Connectivity underlying emotion conflict regulation in older adults with 5-HTTLPR short allele: a preliminary investigation. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 22. issue 9. 2015-04-22. PMID:24119861. |
the serotonin transporter polymorphism short (s) allele is associated with heightened emotional reactivity and reduced emotion regulation, which increases vulnerability to depression and anxiety disorders. |
2015-04-22 |
2023-08-12 |
Not clear |
| Kristan A Leech, Catherine R Kinnaird, T George Hornb. Effects of serotonergic medications on locomotor performance in humans with incomplete spinal cord injury. Journal of neurotrauma. vol 31. issue 15. 2015-04-21. PMID:24742292. |
the effects of enhancement or depression of 5ht signaling on locomotor function have not been thoroughly evaluated in human isci. |
2015-04-21 |
2023-08-13 |
human |
| Pannuru Padmavathi, Vaddi Damodara Reddy, Kodidela Swarnalatha, Reddyvari Hymavathi, N Ch Varadacharyul. Influence of Altered Hormonal Status on Platelet 5-HT and MAO-B Activity in Cigarette Smokers. Indian journal of clinical biochemistry : IJCB. vol 30. issue 2. 2015-04-17. PMID:25883430. |
in conclusion, our study showed that altered testosterone and cortisol levels may aggravate behavior, mood disturbances and symptoms of depression by decreasing platelet 5-ht and mao-b activity in smokers. |
2015-04-17 |
2023-08-13 |
human |
| Wiesław Jerzy Cubala, Jerzy Landowski, Anna Chrzanowsk. Salivary 5-hydroxyindole acetic acid (5-HIAA) in drug-naïve patients with short-illness-duration first episode major depressive disorder. Neuro endocrinology letters. vol 35. issue 8. 2015-04-15. PMID:25702305. |
serotonin is primarily metabolized to 5-hydroxyindole acetic acid (5-hiaa) and its plasma, urinary or cerebrospinal fluid concentrations were extensively studied in depression. |
2015-04-15 |
2023-08-13 |
Not clear |
| Althaf Ansary, Samuel Ibhanesebhor, Chikkanayakanahalli Manjunath. Myoclonic seizures in a preterm baby: is this a presentation of venlafaxine withdrawal? Singapore medical journal. vol 55. issue 4. 2015-04-13. PMID:24763844. |
venlafaxine, a serotonin and norepinephrine reuptake inhibitor, is increasingly used in pregnant women with pre-existing depression who require continued treatment. |
2015-04-13 |
2023-08-13 |
Not clear |
| Ze Gao, Hanyu Yuan, Minghan Sun, Zhen Wang, Yiqin He, Dexiang Li. The association of serotonin transporter gene polymorphism and geriatric depression: a meta-analysis. Neuroscience letters. vol 578. 2015-04-13. PMID:24996193. |
the association of serotonin transporter gene polymorphism and geriatric depression: a meta-analysis. |
2015-04-13 |
2023-08-13 |
Not clear |
| Ze Gao, Hanyu Yuan, Minghan Sun, Zhen Wang, Yiqin He, Dexiang Li. The association of serotonin transporter gene polymorphism and geriatric depression: a meta-analysis. Neuroscience letters. vol 578. 2015-04-13. PMID:24996193. |
serotonin-transporter-linked promoter region (5-httlpr) polymorphism is the genetic variant coding for the serotonin transporter and may play an important role in the etiology of depression. |
2015-04-13 |
2023-08-13 |
Not clear |