| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kelly E Dunham, B Jill Vento. Improving serotonin fast-scan cyclic voltammetry detection: new waveforms to reduce electrode fouling. The Analyst. vol 145. issue 22. 2021-05-14. PMID:32955048. |
serotonin is a neuromodulator implicated in depression that is often measured in real-time by fast-scan cyclic voltammetry (fscv). |
2021-05-14 |
2023-08-13 |
drosophila_melanogaster |
| Francesco Corallo, Chiara Scarfì, Francesca Antonia Arcadi, Caterina Formica, Marcella Di Cara, Rosanna Palmeri, Laura Romeo, Viviana Lo Buono, Placido Bramanti, Silvia Marino, Maria Cristina De Col. Role of functional pharmacological therapy in post-stroke depression: a narrative review. The Journal of international medical research. vol 48. issue 10. 2021-05-14. PMID:33081542. |
we conducted a narrative review to investigate whether antidepressant therapy, including the use of selective serotonin reuptake inhibitors (ssris) or serotonin-norepinephrine reuptake inhibitors (snris) or the use of supportive drugs (i.e., citicoline or choline alfoscerate) as a substitute for antidepressant therapy, reduces depression in patients with cerebrovascular diseases. |
2021-05-14 |
2023-08-13 |
Not clear |
| Elena Y Demireva, Deepika Suri, Emanuela Morelli, Darshini Mahadevia, Nao Chuhma, Catia M Teixeira, Annette Ziolkowski, Marc Hersh, James Fifer, Sneha Bagchi, Alexei Chemiakine, Holly Moore, Jay A Gingrich, Peter Balsam, Stephen Rayport, Mark S Ansorg. 5-HT2C receptor blockade reverses SSRI-associated basal ganglia dysfunction and potentiates therapeutic efficacy. Molecular psychiatry. vol 25. issue 12. 2021-05-14. PMID:30120415. |
serotonin (5-ht) selective reuptake inhibitors (ssris) are widely used in the treatment of depression and anxiety disorders, but responsiveness is uncertain and side effects often lead to discontinuation. |
2021-05-14 |
2023-08-13 |
mouse |
| Hugo R Arias, Katarzyna M Targowska-Duda, Jesús García-Colunga, Marcelo O Ortell. Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors? Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-13. PMID:33917953. |
it is generally assumed that selective serotonin reuptake inhibitors (ssris) induce antidepressant activity by inhibiting serotonin (5-ht) reuptake transporters, thus elevating synaptic 5-ht levels and, finally, ameliorates depression symptoms. |
2021-05-13 |
2023-08-13 |
Not clear |
| Hugo R Arias, Katarzyna M Targowska-Duda, Jesús García-Colunga, Marcelo O Ortell. Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors? Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-13. PMID:33917953. |
studies on dorsal raphe nucleus serotoninergic neurons support the concept that ssri-induced nachr inhibition decreases the glutamatergic hyperstimulation observed in stress conditions, which compensates the excessive 5-ht overflow in these neurons and, consequently, ameliorates depression symptoms. |
2021-05-13 |
2023-08-13 |
Not clear |
| Mario Lepore, Niall Campbel. Sertraline as a rare cause of interstitial lung disease. Oxford medical case reports. vol 2021. issue 4. 2021-05-07. PMID:33948187. |
sertraline, a selective serotonin reuptake inhibitor, is commonly prescribed for the treatment of moderate-to-severe depression. |
2021-05-07 |
2023-08-13 |
Not clear |
| Hui-Qian Cai, Sheng-Yong Su, Qi Dai, Xiang-Yu Jiang, Xi Zhang, Mei Huang, An Li. [Clinical observation of acupuncture combined with moxibustion on college students with depression]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 4. 2021-05-04. PMID:33932000. |
to observe the clinical efficacy of acupuncture combined with moxibustion with seed-sized moxa cone in the treatment of depression in college students, and explore its effect on serum 5-hydroxytryptamine (5-ht). |
2021-05-04 |
2023-08-13 |
Not clear |
| Wenlu Pan, Kexin Lyu, Hongzheng Zhang, Cuixian Li, Peng Chen, Ming Ying, Fangyi Chen, Jie Tan. Attenuation of auditory mismatch negativity in serotonin transporter knockout mice with anxiety-related behaviors. Behavioural brain research. vol 379. 2021-05-03. PMID:31783087. |
as the first-line antidepressant drugs, selective serotonin reuptake inhibitors (ssris) have efficacy in controlling the symptoms of depression. |
2021-05-03 |
2023-08-13 |
mouse |
| Vatsalya Vatsalya, Maiying Kong, Luis M Marsano, Zimple Kurlawala, Kan V Chandras, Melanie L Schwandt, Vijay A Ramchandani, Craig J McClai. Interaction of Heavy Drinking Patterns and Depression Severity Predicts Efficacy of Quetiapine Fumarate XR in Lowering Alcohol Intake in Alcohol Use Disorder Patients. Substance abuse : research and treatment. vol 14. 2021-04-29. PMID:32963470. |
shared etiological pathways of dopamine and serotonin neurotransmission play a central role in heavy alcohol intake and exacerbation in the symptoms of depression.we investigated the treatment efficacy of quetiapine fumarate extended release (xr) in lowering alcohol intake in alcohol use disorder (aud) patients indicated by the shared alleviation of depression ratings and patterns of heavy drinking. |
2021-04-29 |
2023-08-13 |
Not clear |
| Gerhard Gründer, Paul Cummin. Serotonin and amyloid deposition: A link between depression and Alzheimer's disease?: An Editorial Highlight on "Pimavanserin, a 5HT Journal of neurochemistry. vol 156. issue 5. 2021-04-28. PMID:33459383. |
serotonin and amyloid deposition: a link between depression and alzheimer's disease? |
2021-04-28 |
2023-08-13 |
Not clear |
| Maya Amitai, Michal Taler, Reut Ben-Baruch, Maya Lebow, Ron Rotkopf, Alan Apter, Silvana Fennig, Abraham Weizman, Alon Che. Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:31887416. |
selective serotonin reuptake inhibitors (ssris) are commonly used to treat anxiety and/or depression in pediatric populations. |
2021-04-27 |
2023-08-13 |
Not clear |
| Claudia Vignali, Matteo Moretti, Jessica Quaiotti, Francesca Freni, Luca Tajana, Antonio Marco Maria Osculati, Luca Morin. Distribution of Fluvoxamine and Identification of the Main Metabolite in a Fatal Intoxication. Journal of analytical toxicology. vol 45. issue 4. 2021-04-27. PMID:32672818. |
fluvoxamine is a selective serotonin reuptake inhibitor, with a half-life of about 30 hours, that is commonly prescribed in the treatment of depression and obsessive and compulsive disorders. |
2021-04-27 |
2023-08-13 |
Not clear |
| Hiroko Miyagishi, Minoru Tsuji, Kazuya Miyagawa, Kazuhiro Kurokawa, Atsumi Mochida-Saito, Kohei Takahashi, Kumiko Ishige, Hiroshi Taked. Characterization of 5-HT Neuroscience letters. vol 733. 2021-04-26. PMID:32461107. |
characterization of 5-ht the ability to adapt to stress is an essential defensive function of a living body, and disturbance of this ability in the brain may contribute to the development of affective illness including major depression and anxiety disorders. |
2021-04-26 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Patrizia Ambrogini, Barbara Chruścicka, Maria Lindskog, Minerva Crespo-Ramirez, Juan C Hernández-Mondragón, Miguel Perez de la Mora, Harriët Schellekens, Kjell Fux. The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects. International journal of molecular sciences. vol 22. issue 4. 2021-04-23. PMID:33672070. |
the role of central serotonin neurons and 5-ht heteroreceptor complexes in the pathophysiology of depression: a historical perspective and future prospects. |
2021-04-23 |
2023-08-13 |
Not clear |
| Mariam Bonyadi Camacho, Warut D Vijitbenjaronk, Thomas J Anastasi. Computational modeling of the monoaminergic neurotransmitter and male neuroendocrine systems in an analysis of therapeutic neuroadaptation to chronic antidepressant. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 31. 2021-04-22. PMID:31831204. |
second-line depression treatment involves augmentation with one (rarely two) additional drugs, of chronic administration of a selective serotonin reuptake inhibitor (ssri), which is the first-line depression treatment. |
2021-04-22 |
2023-08-13 |
Not clear |
| Edwin N Aroke, Alexis N Robinson, Bryan A Wilbank. Perioperative Considerations for Patients With Major Depressive Disorder Undergoing Surgery. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses. vol 35. issue 2. 2021-04-20. PMID:31955898. |
major depression affects virtually all major systems in the human body, and most antidepressants affect dopamine, norepinephrine, and serotonin levels or alter their target receptors. |
2021-04-20 |
2023-08-13 |
human |
| Silvia Vincentiis, Juliana A Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Francisco Arruda, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo F Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 117. 2021-04-20. PMID:33639436. |
genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. |
2021-04-20 |
2023-08-13 |
Not clear |
| Cezary Chojnacki, Tomasz Popławski, Jan Chojnacki, Michał Fila, Paulina Konrad, Janusz Blasia. Tryptophan Intake and Metabolism in Older Adults with Mood Disorders. Nutrients. vol 12. issue 10. 2021-04-19. PMID:33081001. |
the role of serotonin in the pathogenesis of depression is well-documented, while the involvement of other tryptophan (trp) metabolites generated in the kynurenine pathway is less known. |
2021-04-19 |
2023-08-13 |
human |
| Simone Carneiro-Nascimento, William Powell, Michaela Uebel, Michaela Buerge, Hannes Sigrist, Michael Patterson, Christopher R Pryce, Jolanta Opacka-Juffr. Region- and receptor-specific effects of chronic social stress on the central serotonergic system in mice. IBRO neuroscience reports. vol 10. 2021-04-19. PMID:33861815. |
serotonin (5-ht), via its receptors expressed in discrete brain regions, modulates aversion and reward processing and is implicated in various psychiatric disorders including depression. |
2021-04-19 |
2023-08-13 |
mouse |
| Yukai Wang, HongYu Liu, Yan Jiang, Xinxiu Shi, Yankun Shao, Zhong Xin X. Meta-analysis of 5-hydroxytryptamine transporter gene promoter region polymorphism and post-stroke depression. The Journal of international medical research. vol 48. issue 6. 2021-04-14. PMID:32495670. |
meta-analysis of 5-hydroxytryptamine transporter gene promoter region polymorphism and post-stroke depression. |
2021-04-14 |
2023-08-13 |
Not clear |