| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eric Achtyes, Sarah A Keaton, LeAnn Smart, Amanda R Burmeister, Patrick L Heilman, Stanislaw Krzyzanowski, Madhavi Nagalla, Gilles J Guillemin, Martha L Escobar Galvis, Chai K Lim, Maria Muzik, Teodor T Postolache, Richard Leach, Lena Brundi. Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31698012. |
our results indicate that severe depression in the post-partum involves dysregulation of the immune response and the kynurenine pathway, with a concomitant reduction in serotonin levels. |
2021-03-08 |
2023-08-13 |
Not clear |
| Beverly H Brummett, Stephen H Boyle, Ilene C Siegler, Cynthia M Kuhn, Allison Ashley-Koch, Charles R Jonassaint, Stephan Züchner, Ann Collins, Edward C Suarez, Redford B William. Correction to: Effects of Environmental Stress and Gender on Associations among Symptoms of Depression and the Serotonin Transporter Gene Linked Polymorphic Region (5-HTTLPR). Behavior genetics. vol 51. issue 2. 2021-03-05. PMID:33346869. |
correction to: effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-httlpr). |
2021-03-05 |
2023-08-13 |
Not clear |
| Chad Compagner, Corey Lester, Michael Dorsc. Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin-Norepinephrine Reuptake Inhibitors. Pharmacy (Basel, Switzerland). vol 9. issue 1. 2021-03-04. PMID:33498697. |
this study looked to characterize the sentiment of online medication reviews of selective serotonin reuptake inhibitors (ssris) and serotonin-norepinephrine reuptake inhibitor (snris) used to treat depression. |
2021-03-04 |
2023-08-13 |
Not clear |
| Soichiro Seno, Satoshi Tomura, Hiromi Miyazaki, Shunichi Sato, Daizoh Saito. Effects of Selective Serotonin Reuptake Inhibitors on Depression-Like Behavior in a Laser-Induced Shock Wave Model. Frontiers in neurology. vol 12. 2021-03-03. PMID:33643190. |
however, the effects of the selective serotonin reuptake inhibitor (ssri) on the depression induced by mild blast traumatic brain injury (btbi) in the long-term remain unclear. |
2021-03-03 |
2023-08-13 |
mouse |
| Judith R Homberg, Jadzia Jagiellowic. A neural model of vulnerability and resilience to stress-related disorders linked to differential susceptibility. Molecular psychiatry. 2021-03-02. PMID:33649455. |
a large body of literature has investigated gene by environment interactions, particularly between the serotonin transporter polymorphism (5-httlpr) and negative environments, on the risk for depression. |
2021-03-02 |
2023-08-13 |
Not clear |
| Luis Agüera-Ortiz, Rocío García-Ramos, Francisco J Grandas Pérez, Jorge López-Álvarez, José Manuel Montes Rodríguez, F Javier Olazarán Rodríguez, Javier Olivera Pueyo, Carmelo Pelegrín Valero, Jesús Porta-Etessa. Focus on Depression in Parkinson's Disease: A Delphi Consensus of Experts in Psychiatry, Neurology, and Geriatrics. Parkinson's disease. vol 2021. 2021-02-26. PMID:33628415. |
efficacious and well-tolerated pharmacological options for parkinson's comorbid depression were selective serotonin reuptake inhibitors (especially sertraline), dual-action serotonin and norepinephrine reuptake inhibitors (venlafaxine, desvenlafaxine, and duloxetine), multimodal (vortioxetine, bupropion, mirtazapine, and tianeptine), and anti-parkinsonian dopamine agonists (pramipexole, ropinirole, and rotigotine). |
2021-02-26 |
2023-08-13 |
Not clear |
| Suzanne Vrshek-Schallhorn, Susan Mineka, Richard E Zinbarg, Michelle G Craske, James W Griffith, Jonathan Sutton, Eva E Redei, Kate Wolitzky-Taylor, Constance Hammen, Emma K Ada. Refining the Candidate Environment: Interpersonal Stress, the Serotonin Transporter Polymorphism, and Gene-Environment Interactions in Major Depression. Clinical psychological science : a journal of the Association for Psychological Science. vol 2. issue 3. 2021-02-26. PMID:27446765. |
refining the candidate environment: interpersonal stress, the serotonin transporter polymorphism, and gene-environment interactions in major depression. |
2021-02-26 |
2023-08-13 |
Not clear |
| Yan-Ling Qiao, Jun-Jun Zhou, Jia-Hao Liang, Xiao-Peng Deng, Zhan-Jun Zhang, Hui-Lian Huang, Song Li, Shu-Fang Dai, Chun-Qing Liu, Zhi-Lin Luan, Zhen-Long Yu, Cheng-Peng Sun, Xiao-Chi M. Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 81. 2021-02-24. PMID:33360346. |
uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-ht depression is a pervasive or persistent mental disorder that causes mood, cognitive and memory deficits. |
2021-02-24 |
2023-08-13 |
mouse |
| Ehab Tousson, Ezar Hafez, Somia Zaki, Amani Gad, Rehab M Elgharabaw. Evaluation of the testicular protection conferred by damiana (Turnera diffusa Willd.) against amitriptyline-induced testicular toxicity, DNA damage and apoptosis in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 132. 2021-02-19. PMID:33035829. |
psychiatric drugs, such as antidepressants, are used to treat depression based on their ability to modify chemical imbalances of the key neurotransmitters in the brain, including dopamine, serotonin, and norepinephrine. |
2021-02-19 |
2023-08-13 |
rat |
| Wen Shan Yang, Zhen-Guo Shi, Xian-Zhe Dong, Ping Liu, Meng-Li Chen, Yuan H. Involvement of 5-HT-BDNF signaling axis in mediating synergistic antidepressant-like effects after combined administration of two oligosaccharide esters. Food science & nutrition. vol 9. issue 2. 2021-02-19. PMID:33598202. |
potential mechanisms of depression involving herbal medicines and their specific compounds include elevated 5-ht level and downstream bdnf pathway. |
2021-02-19 |
2023-08-13 |
Not clear |
| Wen Shan Yang, Zhen-Guo Shi, Xian-Zhe Dong, Ping Liu, Meng-Li Chen, Yuan H. Involvement of 5-HT-BDNF signaling axis in mediating synergistic antidepressant-like effects after combined administration of two oligosaccharide esters. Food science & nutrition. vol 9. issue 2. 2021-02-19. PMID:33598202. |
thus, the antidepressant properties of both these compounds can be attributed to their ability to influence 5-ht and bdnf pathway, and thereby suggesting that this combination strategy can definitely act as alternative therapy for depression disorder with very limited side effects. |
2021-02-19 |
2023-08-13 |
Not clear |
| Sajedeh Mosaffa, Hanieh Ahmadi, Fatemeh Khakpai, Mohaddeseh Ebrahimi-Ghiri, Mohammad-Reza Zarrindas. Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice. Psychopharmacology. vol 238. issue 1. 2021-02-16. PMID:33190164. |
β-carbolines and serotonin (5-ht) systems are involved in the modulation of depression and anxiety behaviors. |
2021-02-16 |
2023-08-13 |
mouse |
| Tomoko Soga, Chuin Hau Teo, Ishwar Parha. Genetic and Epigenetic Consequence of Early-Life Social Stress on Depression: Role of Serotonin-Associated Genes. Frontiers in genetics. vol 11. 2021-02-16. PMID:33584798. |
this review has a particular emphasis on the interaction between early-life social stress and genetic variation of serotonin associate genes including the serotonin transporter gene (5-htt; also known as slc6a4), which are key molecules involved in depression. |
2021-02-16 |
2023-08-13 |
Not clear |
| Karina Shasri Anastasya, Shelly Iskandar, Nur Ati. Eel's Head Powder Reduces Mild-Moderate Depression in Geriatric Individual: Result from Randomized Controlled Trial Study. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2021-02-03. PMID:31998397. |
the underlying mechanism of depression among this set of the population is multifactorial, and one of the most important factors in the pathophysiology of depression is the level of brain serotonin. |
2021-02-03 |
2023-08-13 |
human |
| Daniel Feingold, Aviv Weinstei. Cannabis and Depression. Advances in experimental medicine and biology. vol 1264. 2021-02-03. PMID:33332004. |
finally, there has been little support to the notion that selective serotonin reuptake inhibitors (ssris) may be effective in decreasing depressive symptoms or rates of substance use in adolescents treated for depression and a co-occurring substance use disorder. |
2021-02-03 |
2023-08-13 |
Not clear |
| Tao Yang, Xubo Wang, Lei Liu, Hanwen Chen, Na Wan. Ginkgolide-Platinum(II) Complex GPt(II) Exhibits Therapeutic Effect on Depression in Mice via Upregulation of DA and 5-HT Neurotransmitters. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-02-02. PMID:32484164. |
ginkgolide-platinum(ii) complex gpt(ii) exhibits therapeutic effect on depression in mice via upregulation of da and 5-ht neurotransmitters. |
2021-02-02 |
2023-08-13 |
mouse |
| Adi Eldar-Lissai, Joshua T Cohen, Samantha Meltzer-Brody, Margaret E Gerbasi, Elizabeth Chertavian, Paul Hodgkins, Julia C Bond, Scott J Johnso. Cost-Effectiveness of Brexanolone Versus Selective Serotonin Reuptake Inhibitors for the Treatment of Postpartum Depression in the United States. Journal of managed care & specialty pharmacy. vol 26. issue 5. 2021-01-26. PMID:32191592. |
cost-effectiveness of brexanolone versus selective serotonin reuptake inhibitors for the treatment of postpartum depression in the united states. |
2021-01-26 |
2023-08-13 |
Not clear |
| Anna D Burke, Danielle Goldfarb, Padmaja Bollam, Sehar Khokhe. Diagnosing and Treating Depression in Patients with Alzheimer's Disease. Neurology and therapy. vol 8. issue 2. 2021-01-10. PMID:31435870. |
clinical consensus and research appear to support selective serotonin reuptake inhibitors as a first choice for the pharmacological treatment of depression in patients with dementia. |
2021-01-10 |
2023-08-13 |
Not clear |
| Yi-Fan Jiang, Jian Liu, Jie Yang, Yuan Guo, Wei Hu, Jin Zhang, Xue-Mei La, Wen Xie, Hui-Sheng Wang, Li Zhan. Involvement of the Dorsal Hippocampus 5-HT1A Receptors in the Regulation of Depressive-Like Behaviors in Hemiparkinsonian Rats. Neuropsychobiology. vol 79. issue 3. 2021-01-04. PMID:31940619. |
lines of evidence have indicated that the hippocampus and serotonin 1a (5-ht1a) receptors are related to the regulation of depression. |
2021-01-04 |
2023-08-13 |
rat |
| Timothy R Hudd, Christie S Blake, Yahiada Rimola-Dejesus, Thu-Trang Nguyen, Kathy Zaike. A Case Report of Serotonin Syndrome in a Patient on Selective Serotonin Reuptake Inhibitor (SSRI) Monotherapy. Journal of pharmacy practice. vol 33. issue 2. 2021-01-04. PMID:31030620. |
paroxetine is a selective serotonin reuptake inhibitor (ssri) with several indications, one of which is for depression. |
2021-01-04 |
2023-08-13 |
Not clear |