| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mal-Soon Shin, Sang-Seo Park, Jae-Min Lee, Tae-Woon Kim, Young-Pyo Ki. Treadmill exercise improves depression-like symptoms by enhancing serotonergic function through upregulation of 5-HT Journal of exercise rehabilitation. vol 13. issue 1. 2020-10-01. PMID:28349031. |
treadmill exercise improves depression-like symptoms by enhancing serotonergic function through upregulation of 5-ht the olfactory bulbectomy (obx) is a well-known method inducing animal model of depression. |
2020-10-01 |
2023-08-13 |
rat |
| Mal-Soon Shin, Sang-Seo Park, Jae-Min Lee, Tae-Woon Kim, Young-Pyo Ki. Treadmill exercise improves depression-like symptoms by enhancing serotonergic function through upregulation of 5-HT Journal of exercise rehabilitation. vol 13. issue 1. 2020-10-01. PMID:28349031. |
depression is associated with dysfunction of serotonin (5-hydroxytryptamine, 5-ht) system. |
2020-10-01 |
2023-08-13 |
rat |
| İpek Sönmez, Ferdi Köşge. Menstrual Cycle in Schizophrenic Patients: Review with a Case. Noro psikiyatri arsivi. vol 52. issue 4. 2020-10-01. PMID:28360750. |
if depression and anxiety symptoms are present, selective serotonin reuptake inhibitors can be used. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ravi Doobay, Lili Sun, Amish Shah, Pardeep Masuta, Zachary Shepher. SSRI Facilitated Crack Dancing. Case reports in neurological medicine. vol 2017. 2020-10-01. PMID:28487792. |
we present a 32-year-old male who had been using cocaine for many years and was recently started on paroxetine, a selective serotonin reuptake inhibitor (ssri) for worsening depression four weeks before presentation. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ning-Ning Song, Ying Huang, Xin Yu, Bing Lang, Yu-Qiang Ding, Lei Zhan. Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28713247. |
these recent findings provide unique insights to interpret the multifaceted roles of central 5-ht on adult hippocampal neurogenesis and its associated effects on depression. |
2020-10-01 |
2023-08-13 |
mouse |
| Yang Yang, Zhiying Hu, Xiaoxue Du, Henry Davies, Xue Huo, Marong Fan. miR-16 and Fluoxetine Both Reverse Autophagic and Apoptotic Change in Chronic Unpredictable Mild Stress Model Rats. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28790887. |
in the clinic selective serotonin reuptake inhibitors (ssris), like fluoxetine, remain the primary treatment for major depression. |
2020-10-01 |
2023-08-13 |
rat |
| John K Drisdale Iii, Monica G Thornhill, Alexandre R Vieir. Specific Central Nervous System Medications Are Associated with Temporomandibular Joint Symptoms. International journal of dentistry. vol 2017. 2020-10-01. PMID:28791048. |
there is evidence of association between bruxism and the increasingly common central nervous system stimulants prescribed for attention deficit hyperactivity disorder (adhd), as well as the selective serotonin reuptake inhibitors (ssris) often prescribed for depression or anxiety. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Xiang Li, Alexander O Tarakanov, David Savelli, Manuel Narváez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida Díaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS omega. vol 2. issue 8. 2020-10-01. PMID:28920103. |
studies on serotonin-selective reuptake inhibitors have established that disturbances in the ascending 5-ht neuron systems and their 5-ht receptor subtypes and collateral networks to the forebrain contribute to the etiology of major depression and are targets for treatment. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Xiang Li, Alexander O Tarakanov, David Savelli, Manuel Narváez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida Díaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS omega. vol 2. issue 8. 2020-10-01. PMID:28920103. |
these state-of-the-art developments are in line with the hypothesis that the development of major depression can involve an imbalance of the activity between different types of 5-ht isoreceptors. |
2020-10-01 |
2023-08-13 |
Not clear |
| Raquel Romay-Tallon, Tania Rivera-Baltanas, Josh Allen, Jose M Olivares, Lisa E Kalynchuk, Hector J Carunch. Comparative study of two protocols for quantitative image-analysis of serotonin transporter clustering in lymphocytes, a putative biomarker of therapeutic efficacy in major depression. Biomarker research. vol 5. 2020-10-01. PMID:29018523. |
comparative study of two protocols for quantitative image-analysis of serotonin transporter clustering in lymphocytes, a putative biomarker of therapeutic efficacy in major depression. |
2020-10-01 |
2023-08-13 |
human |
| Raquel Romay-Tallon, Tania Rivera-Baltanas, Josh Allen, Jose M Olivares, Lisa E Kalynchuk, Hector J Carunch. Comparative study of two protocols for quantitative image-analysis of serotonin transporter clustering in lymphocytes, a putative biomarker of therapeutic efficacy in major depression. Biomarker research. vol 5. 2020-10-01. PMID:29018523. |
the pattern of serotonin transporter clustering on the plasma membrane of lymphocytes extracted from human whole blood samples has been identified as a putative biomarker of therapeutic efficacy in major depression. |
2020-10-01 |
2023-08-13 |
human |
| Bangshan Liu, Jin Liu, Mi Wang, Yan Zhang, Lingjiang L. From Serotonin to Neuroplasticity: Evolvement of Theories for Major Depressive Disorder. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:29033793. |
the serotonin (5-ht) hypothesis of depression has played an important role in the history of psychiatry, yet it has also been criticized for the delayed onset and inadequate efficacy of selective serotonin reuptake inhibitors (ssris). |
2020-10-01 |
2023-08-13 |
Not clear |
| Meshal A Sultan, Darren B Courtne. Adjunctive Trazodone and Depression Outcome in Adolescents Treated with Serotonin Re-uptake Inhibitors. Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent. vol 26. issue 3. 2020-10-01. PMID:29056986. |
adjunctive trazodone and depression outcome in adolescents treated with serotonin re-uptake inhibitors. |
2020-10-01 |
2023-08-13 |
Not clear |
| Elisabet Londo. Practical Treatment of Lewy Body Disease in the Clinic: Patient and Physician Perspectives. Neurology and therapy. vol 7. issue 1. 2020-10-01. PMID:29260408. |
in the treatment of depression and anxiety it is beneficial to use agents affecting both noradrenalin and serotonin. |
2020-10-01 |
2023-08-13 |
Not clear |
| Meiyan Liu, Wanlin Wei, Christopher R Stone, Lijun Zhang, Guoxiang Tian, Jessie N Din. Beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression. Neuropsychiatric disease and treatment. vol 14. 2020-10-01. PMID:29588593. |
beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression. |
2020-10-01 |
2023-08-13 |
rat |
| Meiyan Liu, Wanlin Wei, Christopher R Stone, Lijun Zhang, Guoxiang Tian, Jessie N Din. Beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression. Neuropsychiatric disease and treatment. vol 14. 2020-10-01. PMID:29588593. |
the purpose of this study was to investigate the therapeutic effects of trimetazidine on 5-ht and serotonin transporter (sert) expression in experimentally induced myocardial infarction (mi), depression, and mi + depression. |
2020-10-01 |
2023-08-13 |
rat |
| Sang Won Jeon, Yong-Ku Ki. The role of neuroinflammation and neurovascular dysfunction in major depressive disorder. Journal of inflammation research. vol 11. 2020-10-01. PMID:29773951. |
neuroinflammation is involved in the pathophysiology of depression by increasing proinflammatory cytokines, activating the hypothalamus-pituitary-adrenal axis, increasing glucocorticoid resistance, and affecting serotonin synthesis and metabolism, neuronal apoptosis and neurogenesis, and neuroplasticity. |
2020-10-01 |
2023-08-13 |
Not clear |
| Min Huang, Yubin Liang, Hongda Chen, Binchu Xu, Cuicui Chai, Pengfei Xin. The Role of Fluoxetine in Activating Wnt/β-Catenin Signaling and Repressing β-Amyloid Production in an Alzheimer Mouse Model. Frontiers in aging neuroscience. vol 10. 2020-10-01. PMID:29910725. |
fluoxetine (flx) is one of the selective serotonin reuptake inhibitors (ssris) antidepressants, which could be used to relieve depression and anxiety among ad patients. |
2020-10-01 |
2023-08-13 |
mouse |
| Yasar Sattar, John Wilson, Ali M Khan, Mahwish Adnan, Daniel Azzopardi Larios, Shristi Shrestha, Quazi Rahman, Zeeshan Mansuri, Ali Hassan, Nirav B Patel, Nargis Tariq, Sharaad Latchana, Stefany C Lopez Pantoja, Sadiasept Vargas, Naveed A Shaikh, Fawaduzzaman Syed, Daaman Mittal, Fatima Rumes. A Review of the Mechanism of Antagonism of N-methyl-D-aspartate Receptor by Ketamine in Treatment-resistant Depression. Cureus. vol 10. issue 5. 2020-10-01. PMID:30034974. |
the biochemical processes involved in depression go beyond serotonin, norepinephrine, and dopamine. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yuki Higuchi, Tomoko Soga, Ishwar S Parha. Potential Roles of microRNAs in the Regulation of Monoamine Oxidase A in the Brain. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30271325. |
monoamine oxidase a (mao-a) is an enzyme that regulates the levels of monoamine neurotransmitters, such as serotonin, noradrenaline and dopamine and it has been used as a therapeutic target for depression. |
2020-10-01 |
2023-08-13 |
Not clear |