| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer N K Nyarko, Maa O Quartey, Ryan M Heistad, Paul R Pennington, Lisa J Poon, Kaeli J Knudsen, Odette Allonby, Amr M El Zawily, Andrew Freywald, Gail Rauw, Glen B Baker, Darrell D Moussea. Glycosylation States of Pre- and Post-synaptic Markers of 5-HT Neurons Differ With Sex and 5-HTTLPR Genotype in Cortical Autopsy Samples. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30147642. |
the serotonin (5-hydroxytryptamine, 5-ht) transporter (5-htt) gene-linked polymorphic region (5-httlpr) is thought to alter 5-ht signaling and contribute to behavioral and cognitive phenotypes in depression as well as alzheimer disease (ad). |
2020-09-30 |
2023-08-13 |
Not clear |
| Jan Albert Nicolaas Groot, Leonore Ten Bokum, Hubertus Laurentius Antonius van den Oeve. Late presentation of Torsades de Pointes related to fluoxetine following a multiple drug overdose. Journal of intensive care. vol 6. 2020-09-30. PMID:30214811. |
fluoxetine is a selective serotonin reuptake inhibitor (ssri) commonly used in the treatment of depression. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kuo-Jung Chang, Yu-Jung Chen, Jing-Yi Chung, Chen-Cheng Lin, Yia-Ping Li. Effects of 5HT1A Activation on Depression Profile Following 5-HT Depletion in Rats Lacking Social Attachment Since Weanling. Psychiatry investigation. vol 15. issue 10. 2020-09-30. PMID:30301302. |
effects of 5ht1a activation on depression profile following 5-ht depletion in rats lacking social attachment since weanling. |
2020-09-30 |
2023-08-13 |
rat |
| Hui Li, Tong Wang, Cuige Shi, Yutao Yang, Xiaoxiao Li, Yan Wu, Zhi-Qing David X. Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30487761. |
inhibition of galr1 in pfc alleviates depressive-like behaviors in postpartum depression rat model by upregulating creb-bndf and 5-ht levels. |
2020-09-30 |
2023-08-13 |
rat |
| Yan-Ping Wu, Hua-Ying Gao, Shu-Hua Ouyang, Hiroshi Kurihara, Rong-Rong He, Yi-Fang L. Predator stress-induced depression is associated with inhibition of hippocampal neurogenesis in adult male mice. Neural regeneration research. vol 14. issue 2. 2020-09-30. PMID:30531013. |
stress has been suggested to disturb the 5-hydroxytryptamine system and decrease neurogenesis, which contribute to the development of depression. |
2020-09-30 |
2023-08-13 |
mouse |
| Yashika Bansal, Raghunath Singh, Ishwar Parhar, Anurag Kuhad, Tomoko Sog. Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31164818. |
however, due to delayed and/or poor performance of selective serotonin reuptake inhibitors in treating depressive symptoms, the role of the serotonergic system in depression has been recently questioned further. |
2020-09-30 |
2023-08-13 |
Not clear |
| Bruno Müller-Oerlinghausen, Mohammed T Abou-Sale. Alec J. Coppen-A pioneering psychiatrist who discovered the pivotal role of serotonin in the pathogenesis of depression as well as the antisuicidal effect of lithium. International journal of bipolar disorders. vol 7. issue 1. 2020-09-30. PMID:31263970. |
alec j. coppen-a pioneering psychiatrist who discovered the pivotal role of serotonin in the pathogenesis of depression as well as the antisuicidal effect of lithium. |
2020-09-30 |
2023-08-13 |
Not clear |
| Bernadette Mdawar, Elias Ghossoub, Rita Khour. Selective serotonin reuptake inhibitors and Alzheimer's disease. Neural regeneration research. vol 15. issue 1. 2020-09-30. PMID:31535641. |
in humans, studies focusing on subjects with a prior history of depression also showed a delay in the onset of ad in those treated with most selective serotonin reuptake inhibitors. |
2020-09-30 |
2023-08-13 |
mouse |
| Carla Luzzi, Konrad Salata, Carine Djaiani, Maxim Gershinsky, Vivek Rao, Jo Carroll, Rita Katznelso. Selective serotonin re-uptake inhibitors: risk of blood product transfusion and inotrope requirements in patients undergoing cardiac surgery. Journal of thoracic disease. vol 11. issue 8. 2020-09-30. PMID:31559056. |
the first-line pharmacological treatment modality for depression includes selective serotonin re-uptake inhibitors (ssris). |
2020-09-30 |
2023-08-13 |
Not clear |
| Hridya Jayamohananan, Maneesha Kalappurackal Manoj Kumar, Aneesh T . 5-HIAA as a Potential Biological Marker for Neurological and Psychiatric Disorders. Advanced pharmaceutical bulletin. vol 9. issue 3. 2020-09-30. PMID:31592064. |
many theories suggest that the variations in serotonin level could lead to the development of many neurological and psychiatric disorders like alzheimer's disease (ad), schizophrenia, depression and so on. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kei Odai, Tohru Sugimoto, Etsuro It. Biophysics and physicobiology. vol 16. 2020-09-30. PMID:31608202. |
5-hydroxytryptamine (5-ht; serotonin) regulates metabolism and various homeostatic mechanisms in the body, and is involved in depression. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hye-Geum Kim, Bon-Hoon Koo, Seung Woo Lee, Eun-Jin Cheo. Apathy syndrome in a patient previously treated with selective serotonin reuptake inhibitors for depression. Yeungnam University journal of medicine. vol 36. issue 3. 2020-09-30. PMID:31620640. |
apathy syndrome in a patient previously treated with selective serotonin reuptake inhibitors for depression. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hye-Geum Kim, Bon-Hoon Koo, Seung Woo Lee, Eun-Jin Cheo. Apathy syndrome in a patient previously treated with selective serotonin reuptake inhibitors for depression. Yeungnam University journal of medicine. vol 36. issue 3. 2020-09-30. PMID:31620640. |
in this report, we present the case of a 67-year-old woman with a history of receiving selective serotonin reuptake inhibitor (ssri) treatment for depression. |
2020-09-30 |
2023-08-13 |
Not clear |
| Noreen Samad, Farzana Yasmin, Natasha Manzoo. Biomarkers in Drug Free Subjects with Depression : Correlation with Tryptophan. Psychiatry investigation. vol 16. issue 12. 2020-09-29. PMID:31711278. |
in view of a role of tryptophan (trp), selenium (se), vitamin d (vit d), magnesium (mg) and serotonin in depression, the present study concerns to evaluate the circulating levels of trp, se, vit d, mg and serotonin in depression as well as the correlation between trp and other serum analytes is also established. |
2020-09-29 |
2023-08-13 |
human |
| Randall S. Stafford, Ellen A. MacDonald, Stan N. Finkelstei. National Patterns of Medication Treatment for Depression, 1987 to 2001. Primary care companion to the Journal of clinical psychiatry. vol 3. issue 6. 2020-09-29. PMID:15014590. |
background: we investigated trends in antidepressant use, as well as broader changes in depression treatment, following the availability of selective serotonin reuptake inhibitors (ssris). |
2020-09-29 |
2023-08-12 |
Not clear |
| Patricia A. Marken, J Stuart Munr. Selecting a Selective Serotonin Reuptake Inhibitor: Clinically Important Distinguishing Features. Primary care companion to the Journal of clinical psychiatry. vol 2. issue 6. 2020-09-29. PMID:15014630. |
selective serotonin reuptake inhibitors (ssris) are widely prescribed to treat depression. |
2020-09-29 |
2023-08-12 |
Not clear |
| Randall S. Stafford, John C. Ausiello, Bismruta Misra, Demet Sagla. National Patterns of Depression Treatment in Primary Care. Primary care companion to the Journal of clinical psychiatry. vol 2. issue 6. 2020-09-29. PMID:15014631. |
among specific antidepressants, selective serotonin reuptake inhibitors were most often prescribed by primary care physicians (26% of depression visits). |
2020-09-29 |
2023-08-12 |
Not clear |
| Randall S. Stafford, John C. Ausiello, Bismruta Misra, Demet Sagla. National Patterns of Depression Treatment in Primary Care. Primary care companion to the Journal of clinical psychiatry. vol 2. issue 6. 2020-09-29. PMID:15014631. |
conclusion: the predominant use of selective serotonin reuptake inhibitors suggests that primary care physicians have begun to adopt new therapeutic strategies for depression. |
2020-09-29 |
2023-08-12 |
Not clear |
| Larry Culpeppe. Escitalopram: A New SSRI for the Treatment of Depression in Primary Care. Primary care companion to the Journal of clinical psychiatry. vol 4. issue 6. 2020-09-29. PMID:15014711. |
escitalopram is the s-enantiomer of the racemic compound citalopram, a selective serotonin reuptake inhibitor (ssri) widely used for the treatment of depression. |
2020-09-29 |
2023-08-12 |
Not clear |
| Craig H. Mallinckrodt, David J. Goldstein, Michael J. Detke, Yili Lu, John G. Watkin, Pierre V. Tra. Duloxetine: A New Treatment for the Emotional and Physical Symptoms of Depression. Primary care companion to the Journal of clinical psychiatry. vol 5. issue 1. 2020-09-29. PMID:15156243. |
duloxetine, a dual-reuptake inhibitor of serotonin and norepinephrine, may have a positive effect on physical symptoms in addition to efficacy in treating emotional symptoms of depression. |
2020-09-29 |
2023-08-12 |
Not clear |