| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Denise C Vidot, Sapna Deo, Sylvia Daunert, Willie L Joseph, Nestor de la Cruz-Munoz, Sarah E Messia. A Preliminary Study on the Influence of Cannabis and Opioid Use on Weight Loss and Mental Health Biomarkers Post-weight Loss Surgery. Obesity surgery. vol 30. issue 11. 2021-04-14. PMID:32860570. |
this study examined the influence of the independent and combined use of cannabis and opioids on (1) depression and anxiety, (2) duodenum serotonin and cortisol, and (3) total percent weight loss. |
2021-04-14 |
2023-08-13 |
Not clear |
| Yige Liu, Hongfan Li, Xiayue Xu, Yukun Li, Zhutao Wang, Huan Zhu, Xia Zhang, Shan Jiang, Naling Li, Simeng Gu, Fushun Wang, Jason H Huan. The Relationship between Insecure Attachment to Depression: Mediating Role of Sleep and Cognitive Reappraisal. Neural plasticity. vol 2020. 2021-04-07. PMID:32351552. |
previously, we have shown that neuromodulators are important factors in stress-induced emotional disorders, such as depression, for example, serotonin is the major substance for depression. |
2021-04-07 |
2023-08-13 |
Not clear |
| Yige Liu, Hongfan Li, Xiayue Xu, Yukun Li, Zhutao Wang, Huan Zhu, Xia Zhang, Shan Jiang, Naling Li, Simeng Gu, Fushun Wang, Jason H Huan. The Relationship between Insecure Attachment to Depression: Mediating Role of Sleep and Cognitive Reappraisal. Neural plasticity. vol 2020. 2021-04-07. PMID:32351552. |
furthermore, serotonin is the substrate for both sleep and depression. |
2021-04-07 |
2023-08-13 |
Not clear |
| b' Marion Falabr\\xc3\\xa8gue, Anne-Claire Boschat, Romain Jouffroy, Marieke Derquennes, Haidar Djemai, Sylvia Sanquer, Robert Barouki, Xavier Coumoul, Jean-Fran\\xc3\\xa7ois Toussaint, Olivier Hermine, Philippe Noirez, Francine C\\xc3\\xb4t\\xc3\\xa. Lack of Skeletal Muscle Serotonin Impairs Physical Performance. International journal of tryptophan research : IJTR. vol 14. 2021-04-06. PMID:33814916.' |
low levels of the neurotransmitter serotonin have been associated with the onset of depression. |
2021-04-06 |
2023-08-13 |
mouse |
| b' Marion Falabr\\xc3\\xa8gue, Anne-Claire Boschat, Romain Jouffroy, Marieke Derquennes, Haidar Djemai, Sylvia Sanquer, Robert Barouki, Xavier Coumoul, Jean-Fran\\xc3\\xa7ois Toussaint, Olivier Hermine, Philippe Noirez, Francine C\\xc3\\xb4t\\xc3\\xa. Lack of Skeletal Muscle Serotonin Impairs Physical Performance. International journal of tryptophan research : IJTR. vol 14. 2021-04-06. PMID:33814916.' |
but the breakdown of tryptophan into kynurenine during exercise may also alter serotonin synthesis and help limit depression. |
2021-04-06 |
2023-08-13 |
mouse |
| Lokesh Agrawal, Mustafa Korkutata, Sunil Kumar Vimal, Manoj Kumar Yadav, Sanjib Bhattacharyya, Takashi Shig. Therapeutic potential of serotonin 4 receptor for chronic depression and its associated comorbidity in the gut. Neuropharmacology. vol 166. 2021-04-02. PMID:31982703. |
therapeutic potential of serotonin 4 receptor for chronic depression and its associated comorbidity in the gut. |
2021-04-02 |
2023-08-13 |
Not clear |
| Toshi A Furukawa, Andrea Cipriani, Philip J Cowen, Stefan Leucht, Matthias Egger, Georgia Salant. Optimal Dose of Selective Serotonin Reuptake Inhibitors, Venlafaxine, and Mirtazapine in Major Depression: A Systematic Review and Dose-Response Meta-Analysis. Focus (American Psychiatric Publishing). vol 18. issue 2. 2021-04-02. PMID:33343239. |
optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis. |
2021-04-02 |
2023-08-13 |
Not clear |
| Chen Zhu, Xinwei Li, Weiqing Peng, Wei F. Discovery of Novel Indolealkylpiperazine Derivatives as Potent 5-HT Molecules (Basel, Switzerland). vol 25. issue 21. 2021-04-01. PMID:33139658. |
discovery of novel indolealkylpiperazine derivatives as potent 5-ht depression is a severe psychiatric disorder that affects over 100 million people worldwide. |
2021-04-01 |
2023-08-13 |
Not clear |
| Juliana Zambrano, Christopher M Celano, James L Januzzi, Christina N Massey, Wei-Jean Chung, Rachel A Millstein, Jeff C Huffma. Psychiatric and Psychological Interventions for Depression in Patients With Heart Disease: A Scoping Review. Journal of the American Heart Association. vol 9. issue 22. 2021-04-01. PMID:33164638. |
selective serotonin reuptake inhibitors appear to be safe in patients with cardiac disease and to have beneficial effects on depression (and some suggestion of cardiac benefit) in patients with coronary artery disease, with less evidence of their efficacy in heart failure. |
2021-04-01 |
2023-08-13 |
Not clear |
| Juliana Zambrano, Christopher M Celano, James L Januzzi, Christina N Massey, Wei-Jean Chung, Rachel A Millstein, Jeff C Huffma. Psychiatric and Psychological Interventions for Depression in Patients With Heart Disease: A Scoping Review. Journal of the American Heart Association. vol 9. issue 22. 2021-04-01. PMID:33164638. |
selective serotonin reuptake inhibitors may be preferred in the treatment of patients with coronary artery disease, psychotherapy may be preferred in heart failure, and more flexible depression care management approaches have shown promise by potentially using both approaches based on patient needs. |
2021-04-01 |
2023-08-13 |
Not clear |
| Tomoko Soga, Shingo Nakajima, Ishwar S Parha. Expression of Repressor Element 1 Silencing Transcription Factor (REST) in Serotonin Neurons in the Adult Male Nile Tilapia ( Frontiers in neuroanatomy. vol 14. 2021-03-30. PMID:33776659. |
we hypothesized that rest is co-expressed in 5-ht neurons, which, if demonstrated, would be useful to understand the mechanism of 5-ht dysfunction-related disorders such as negative emotions and depression. |
2021-03-30 |
2023-08-13 |
Not clear |
| Chaya Shor, Wanhong Zuo, Jean D Eloy, Jiang-Hong Y. The Emerging Role of LHb CaMKII in the Comorbidity of Depressive and Alcohol Use Disorders. International journal of molecular sciences. vol 21. issue 21. 2021-03-26. PMID:33143210. |
recently, interest in the lateral habenula, a small epithalamic brain structure, has increased because it becomes hyperactive in depression and alcohol use disorders, and can inhibit dopamine and serotonin neurons in the midbrain reward center, the hypofunction of which is believed to be a critical contributor to the etiology of depressive disorders and alcohol use disorders as well as their comorbidities. |
2021-03-26 |
2023-08-13 |
Not clear |
| Marta Torrens, Judit Tirado-Muñoz, Francina Fonseca, Magi Farré, Ana Gonzalez-Pinto, Manuel Arrojo, Miquel Bernardo, Belen Arranz, Marina Garriga, Pilar A Saiz, Gerardo Florez, Jose Manuel Goikolea, Iñaki Zorrilla, Ruth Cunill, Xavier Castells, Elisardo Becoña, Ana Lopez, Luis Sa. Clinical practice guideline on pharmacological and psychological management of adult patients with depression and a comorbid substance use disorder. Adicciones. vol 0. issue 0. 2021-03-26. PMID:33768269. |
our results suggest that 1) in patients with depression and alcohol consumption, the administration of non-selective serotonin reuptake inhibitor (ssri) antidepressants instead of ssri is recommended for improvement of depressive symptoms (strong recommendation). |
2021-03-26 |
2023-08-13 |
Not clear |
| Joanna Grzelczyk, Grażyna Budryn, Jorge Peña-García, Dominik Szwajgier, Ilona Gałązka-Czarnecka, Joanna Oracz, Horacio Pérez-Sánche. Evaluation of the inhibition of monoamine oxidase A by bioactive coffee compounds protecting serotonin degradation. Food chemistry. vol 348. 2021-03-22. PMID:33540300. |
the decrease in 5-ht levels is accompanied by disorders at the affective and somatic levels, leading to depression and disorders of the satiety center. |
2021-03-22 |
2023-08-13 |
Not clear |
| Revathy U Chottekalapanda, Salina Kalik, Jodi Gresack, Alyssa Ayala, Melanie Gao, Wei Wang, Sarah Meller, Ammar Aly, Anne Schaefer, Paul Greengar. AP-1 controls the p11-dependent antidepressant response. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:32439846. |
while the mechanism of ssri action is still unknown, ssris are thought to exert therapeutic effects by elevating extracellular serotonin levels in the brain, and remodel the structural and functional alterations dysregulated during depression. |
2021-03-17 |
2023-08-13 |
Not clear |
| Gustavo R Villas-Boas, Stefânia N Lavorato, Marina M Paes, Pablinny M G de Carvalho, Vanessa C Rescia, Mila S Cunha, Manoel F de Magalhães-Filho, Luis F Ponsoni, Adryano Augustto Valladao de Carvalho, Roseli B de Lacerda, Lais da S Leite, Matheus da S Tavares-Henriques, Luiz A F Lopes, Luiz G R Oliveira, Saulo E Silva-Filho, Ana P S da Silveira, Roberto K N Cuman, Francielli M de S Silva-Comar, Jurandir F Comar, Luana do A Brasileiro, Jussileide N Dos Santos, William R de Freitas, Katyuscya V Leão, Jonatas G da Silva, Raphael C Klein, Mary H F Klein, Bruno H da S Ramos, Cristiane K C Fernandes, Dayane G de L Ribas, Silvia A Oesterreic. Modulation of the Serotonergic Receptosome in the Treatment of Anxiety and Depression: A Narrative Review of the Experimental Evidence. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33673205. |
serotonin (5-ht) receptors are found throughout central and peripheral nervous systems, mainly in brain regions involved in the neurobiology of anxiety and depression. |
2021-03-16 |
2023-08-13 |
Not clear |
| Gustavo R Villas-Boas, Stefânia N Lavorato, Marina M Paes, Pablinny M G de Carvalho, Vanessa C Rescia, Mila S Cunha, Manoel F de Magalhães-Filho, Luis F Ponsoni, Adryano Augustto Valladao de Carvalho, Roseli B de Lacerda, Lais da S Leite, Matheus da S Tavares-Henriques, Luiz A F Lopes, Luiz G R Oliveira, Saulo E Silva-Filho, Ana P S da Silveira, Roberto K N Cuman, Francielli M de S Silva-Comar, Jurandir F Comar, Luana do A Brasileiro, Jussileide N Dos Santos, William R de Freitas, Katyuscya V Leão, Jonatas G da Silva, Raphael C Klein, Mary H F Klein, Bruno H da S Ramos, Cristiane K C Fernandes, Dayane G de L Ribas, Silvia A Oesterreic. Modulation of the Serotonergic Receptosome in the Treatment of Anxiety and Depression: A Narrative Review of the Experimental Evidence. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33673205. |
5-ht receptors are currently promising targets for discovering new drugs for treating disorders ranging from migraine to neuropsychiatric upsets, such as anxiety and depression. |
2021-03-16 |
2023-08-13 |
Not clear |
| Shiyue Cao, Li We. Predictive value of serum CRH/5-HT ratio for postpartum depression. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. vol 151. issue 3. 2021-03-10. PMID:32812654. |
to analyze the changes in the serum levels of crh and 5-ht in women with postpartum depression (ppd) and to study the value of the crh/5-ht ratio for the prediction of ppd. |
2021-03-10 |
2023-08-13 |
Not clear |
| Eric Achtyes, Sarah A Keaton, LeAnn Smart, Amanda R Burmeister, Patrick L Heilman, Stanislaw Krzyzanowski, Madhavi Nagalla, Gilles J Guillemin, Martha L Escobar Galvis, Chai K Lim, Maria Muzik, Teodor T Postolache, Richard Leach, Lena Brundi. Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31698012. |
we analyzed plasma il-1β, il-2, il-6, il-8, tnf-α, tryptophan, serotonin, kynurenine, nicotinamide, quinolinic- and kynurenic acids in post-partum women diagnosed with peripartum onset depression (ppd) and healthy controls (n = 165). |
2021-03-08 |
2023-08-13 |
Not clear |
| Eric Achtyes, Sarah A Keaton, LeAnn Smart, Amanda R Burmeister, Patrick L Heilman, Stanislaw Krzyzanowski, Madhavi Nagalla, Gilles J Guillemin, Martha L Escobar Galvis, Chai K Lim, Maria Muzik, Teodor T Postolache, Richard Leach, Lena Brundi. Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31698012. |
moreover, women with lower serotonin levels were at an increased risk for suicidal behavior, even when adjusting for depression severity, psychosocial factors, age bmi, and medication. |
2021-03-08 |
2023-08-13 |
Not clear |