| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Gratto. Time course analysis of para-chlorophenylalanine induced suppression of self-stimulation behavior. Pharmacology, biochemistry, and behavior. vol 17. issue 4. 1983-02-25. PMID:6217466. |
the hypothesis of a serotonergic basis of reward rests partly on data showing that serotonin (5-ht) depletion by para-chlorophenylalanine (p-cpa) causes depression of self-stimulation (ss) rates. |
1983-02-25 |
2023-08-12 |
Not clear |
| G V Rebec, S D Curtis, K S Zimmerma. Dorsal raphe neurons: self-inhibition by an amphetamine-induced release of endogenous serotonin. Brain research. vol 251. issue 2. 1983-01-27. PMID:7139334. |
the amphetamine-induced depression of firing rate was blocked by a subsequent injection of methiothepin, a putative serotonin autoreceptor antagonist, but not by pretreatment with a-methyl-p-tyrosine which depletes brain catecholamines. |
1983-01-27 |
2023-08-12 |
rat |
| V F Castellucci, A Nairn, P Greengard, J H Schwartz, E R Kande. Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 12. 1983-01-19. PMID:6292379. |
there is evidence that serotonin is the facilitating transmitter and that the depression of the k+ current by serotonin mediated by camp-dependent protein phosphorylation. |
1983-01-19 |
2023-08-12 |
aplysia |
| H Y Meltzer, R Perline, R Lewin. Biological studies of DSM-III psychotic disorders. I. Platelet measures and apomorphine-induced growth hormone response. The Journal of nervous and mental disease. vol 170. issue 12. 1983-01-19. PMID:6754871. |
dsm-iii major affective disorders (bipolar disorder and major depression) can be differentiated from normal controls by the v max of platelet 5-ht. |
1983-01-19 |
2023-08-12 |
Not clear |
| M Shaarawy, M Fayad, A R Nagui, S Abdel-Azi. Serotonin metabolism and depression in oral contraceptive users. Contraception. vol 26. issue 2. 1983-01-19. PMID:7140295. |
serotonin metabolism and depression in oral contraceptive users. |
1983-01-19 |
2023-08-12 |
Not clear |
| M Shaarawy, M Fayad, A R Nagui, S Abdel-Azi. Serotonin metabolism and depression in oral contraceptive users. Contraception. vol 26. issue 2. 1983-01-19. PMID:7140295. |
changes in serotonin metabolism were demonstrated in the depression group before and after tryptophan load test, while in the non-depression group before and after tryptophan load test, while in the non-depression group, these changes were only demonstrated after tryptophan load test. |
1983-01-19 |
2023-08-12 |
Not clear |
| R D Kaplan, J J Man. Altered platelet serotonin uptake kinetics in schizophrenia and depression. Life sciences. vol 31. issue 6. 1982-12-21. PMID:7132568. |
altered platelet serotonin uptake kinetics in schizophrenia and depression. |
1982-12-21 |
2023-08-12 |
Not clear |
| S M Stahl, R D Ciaranello, P A Berge. Platelet serotonin in schizophrenia and depression. Advances in biochemical psychopharmacology. vol 34. 1982-12-18. PMID:6753510. |
platelet serotonin in schizophrenia and depression. |
1982-12-18 |
2023-08-12 |
Not clear |
| H M van Praa. Serotonin precursors in the treatment of depression. Advances in biochemical psychopharmacology. vol 34. 1982-12-18. PMID:6753514. |
serotonin precursors in the treatment of depression. |
1982-12-18 |
2023-08-12 |
Not clear |
| E R Bloc. Alpha-naphthylthiourea (ANTU) protects against hyperoxic depression of pulmonary serotonin uptake. The American review of respiratory disease. vol 126. issue 3. 1982-12-03. PMID:6214977. |
alpha-naphthylthiourea (antu) protects against hyperoxic depression of pulmonary serotonin uptake. |
1982-12-03 |
2023-08-12 |
rat |
| G L Corona, M L Cucchi, G Santagostino, P Frattini, F Zerbi, L Fenoglio, F Savold. Blood noradrenaline and 5-HT levels in depressed women during amitriptyline or lithium treatment. Psychopharmacology. vol 77. issue 3. 1982-12-03. PMID:6812145. |
a more extended analysis of blood amine levels could supply meaningful information on the peripheral action of antidepressive drugs on noradrenaline and serotonin concentrations in depression. |
1982-12-03 |
2023-08-12 |
human |
| A Aberg-Wistedt, S B Ross, K G Jostell, B Sjöquis. A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. II. Biochemical findings. Acta psychiatrica Scandinavica. vol 66. issue 1. 1982-12-02. PMID:6181652. |
a double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. |
1982-12-02 |
2023-08-12 |
rat |
| A Aberg-Wistedt, S B Ross, K G Jostell, B Sjöquis. A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. II. Biochemical findings. Acta psychiatrica Scandinavica. vol 66. issue 1. 1982-12-02. PMID:6181652. |
in a comparative evaluation of zimelidine, a potent serotonin (5-ht) uptake inhibitor, and desipramine, a potent noradrenaline (na) uptake inhibitor, 65 hospitalized patients with endogenous depression were evaluated for the following biochemical variables: 5-ht uptake in platelets, 5-ht concentration in whole blood, inhibition of the 5-ht and na accumulation in rat hypothalamic synaptosomes incubated in the patients' plasma, the excretion of 4-hydroxy-3-methoxyphenyl glycol (hmpg) in urine and the pretreatment levels of the amine metabolites 5-hydroxyindoleacetic acid (5-hiaa), homovanillic acid (hva) and hmpg in cerebrospinal fluid (csf). |
1982-12-02 |
2023-08-12 |
rat |
| A Aberg-Wisted. A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. I. Clinical findings. Acta psychiatrica Scandinavica. vol 66. issue 1. 1982-12-02. PMID:6214925. |
a double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. |
1982-12-02 |
2023-08-12 |
Not clear |
| A Aberg-Wisted. A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. I. Clinical findings. Acta psychiatrica Scandinavica. vol 66. issue 1. 1982-12-02. PMID:6214925. |
a comparative evaluation of zimelidine, a potent and selective serotonin (5-ht) uptake inhibitor, and desipramine, a potent noradrenaline (na) uptake inhibitor, was carried out in a 4-week randomized, double-blind study in 65 hospitalized patients with endogenous depression. |
1982-12-02 |
2023-08-12 |
Not clear |
| A Uza. [Proserotoninergic agents and depression (author's transl)]. L'Encephale. vol 8. issue 2. 1982-10-21. PMID:6286277. |
the proserotoninergic hypothesis of depression has been for a long time founded on biochemical parameters (brain from suicide patients, csf and plasma from depressed patients) or more recently on measurement of platelets 5-ht uptake or imipramine binding. |
1982-10-21 |
2023-08-12 |
human |
| A Georgotas, M Krakowski, S Gersho. Controlled trial of zimelidine, a 5-HT reuptake inhibitor, for treatment of depression. The American journal of psychiatry. vol 139. issue 8. 1982-08-26. PMID:6211994. |
controlled trial of zimelidine, a 5-ht reuptake inhibitor, for treatment of depression. |
1982-08-26 |
2023-08-12 |
Not clear |
| D R Cook, R E Howell, C N Gilli. Xanthine oxidase-induced lung injury inhibits removal of 5-hydroxytryptamine from the pulmonary circulation. Anesthesia and analgesia. vol 61. issue 8. 1982-08-26. PMID:6283949. |
as uptake of 5-ht is the rate-limiting step in 5-ht removal, these data demonstrate dose (time)-related depression of active 5-ht uptake by free radicals generated in vitro. |
1982-08-26 |
2023-08-12 |
Not clear |
| D R Cook, B W Brando. Enflurane, halothane, and isoflurane inhibit removal of 5-hydroxytryptamine from the pulmonary circulation. Anesthesia and analgesia. vol 61. issue 8. 1982-08-26. PMID:7201270. |
as uptake of 5-ht is the rate-limiting step in 5-ht removal, these data demonstrate a uniform depression of 5-ht uptake by the three potent anesthetics. |
1982-08-26 |
2023-08-12 |
rabbit |
| E R Block, F J Schoe. Depression of serotonin uptake by rat lungs exposed to paraquat. The Journal of pharmacology and experimental therapeutics. vol 221. issue 1. 1982-05-27. PMID:7062288. |
depression of serotonin uptake by rat lungs exposed to paraquat. |
1982-05-27 |
2023-08-12 |
rat |