| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R C Murthy, S Lal, D K Saxena, G S Shukla, M M Ali, S V Chandr. Effect of manganese and copper interaction on behavior and biogenic amines in rats fed a 10% casein diet. Chemico-biological interactions. vol 37. issue 3. 1982-01-20. PMID:7296699. |
combined exposure of mn and cu also produced a greater elevation in the levels of dopamine (da) and norepinephrine (ne) and a depression of 5-hydroxytryptamine (5-ht) in the brain of animals fed with a 10% casein diet compared to the animals receiving the 21% casein diet. |
1982-01-20 |
2023-08-12 |
rat |
| C De Montign. Enhancement of the 5-HT neurotransmission by antidepressant treatments. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:6270317. |
little unequivocal evidence exists for a 5-ht deficit in depression. |
1981-12-22 |
2023-08-12 |
human |
| A Ferron, T A Reader, L Descarrie. Responsiveness of cortical neurons to serotonin after 5,7-DHT denervation or PCPA depletion. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:6457141. |
in adult rats under urethane anesthesia, a vast majority of spontaneously active neurons in the frontoparietal cortex undergo a prolonged depression of their firing rate upon microiontophoretic application of 5-ht. |
1981-12-22 |
2023-08-12 |
rat |
| A Ferron, T A Reader, L Descarrie. Responsiveness of cortical neurons to serotonin after 5,7-DHT denervation or PCPA depletion. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:6457141. |
moreover, small ejection currents of 5-ht are sufficient to induce a prolonged depression of the firing rate. |
1981-12-22 |
2023-08-12 |
rat |
| V Bhargava, A Salamy, S Sha. Role of serotonin in the nicotine-induced depression of the brainstem auditory evoked response. Pharmacology, biochemistry, and behavior. vol 15. issue 4. 1981-12-22. PMID:6457306. |
role of serotonin in the nicotine-induced depression of the brainstem auditory evoked response. |
1981-12-22 |
2023-08-12 |
Not clear |
| H R Olpe, R Ortmann, B Fehr, P C Waldmeie. Experimentally induced supersensitivity of neocortical neurons to microiontophoretically administered serotonin. Brain research. vol 224. issue 2. 1981-12-22. PMID:6169411. |
the depressant action of 5-ht on neuronal firing was potentiated with regard to both maximal firing depression and duration of the firing inhibition. |
1981-12-22 |
2023-08-12 |
rat |
| G M Asnis, E J Sachar, U Halbreich, R S Nathan, L Ostrow, M Soloman, F S Halper. Endocrine responses to thyrotropin-releasing hormone in major depressive disorders. Psychiatry research. vol 5. issue 2. 1981-12-21. PMID:6117098. |
the role of possible abnormalities in dopamine and/or serotonin in depression contributing to these endocrine disturbances is discussed. |
1981-12-21 |
2023-08-12 |
Not clear |
| A Aberg-Wistedt, K G Jostell, S B Ross, D Westerlun. Effects of zimelidine and desipramine on serotonin and noradrenaline uptake mechanisms in relation to plasma concentrations and to therapeutic effects during treatment of depression. Psychopharmacology. vol 74. issue 4. 1981-12-15. PMID:6457309. |
effects of zimelidine and desipramine on serotonin and noradrenaline uptake mechanisms in relation to plasma concentrations and to therapeutic effects during treatment of depression. |
1981-12-15 |
2023-08-12 |
rat |
| A Aberg-Wistedt, K G Jostell, S B Ross, D Westerlun. Effects of zimelidine and desipramine on serotonin and noradrenaline uptake mechanisms in relation to plasma concentrations and to therapeutic effects during treatment of depression. Psychopharmacology. vol 74. issue 4. 1981-12-15. PMID:6457309. |
the selective inhibitors of neuronal 5-hydroxytryptamine (5-ht) and noradrenaline (na) uptake, zimelidine and desipramine, were compared in a double blind crossover study of 40 inpatients with endogenous depression. |
1981-12-15 |
2023-08-12 |
rat |
| H Nagayama, J N Hingtgen, M H Apriso. Postsynaptic action by four antidepressive drugs in an animal model of depression. Pharmacology, biochemistry, and behavior. vol 15. issue 1. 1981-12-15. PMID:6974869. |
to further test the new hypersensitive postsynaptic serotonin (5-ht) receptor theory of depression bases on or animal model, it was necessary to demonstrate that some of the currently used antidepressive drugs can block d,l-5-hydroxytryptophan (5-htp) induced depression acting through postsynaptic rather than presynaptic mechanisms. |
1981-12-15 |
2023-08-12 |
rat |
| H Nagayama, J N Hingtgen, M H Apriso. Postsynaptic action by four antidepressive drugs in an animal model of depression. Pharmacology, biochemistry, and behavior. vol 15. issue 1. 1981-12-15. PMID:6974869. |
since acute pretreatment with comparable clinical doses of the antidepressive drugs, mianserin, amitriptyline, imipramine, or iprindole, resulted in blockade of the 5-htp induced depression by 70, 50, 40, and 20% respectively, these drugs can act as antagonists of 5-ht at the postsynaptic serotonin receptor. |
1981-12-15 |
2023-08-12 |
rat |
| E R Block, S A Stalcu. Depression of serotonin uptake by cultured endothelial cells exposed to high O2 tension. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 50. issue 6. 1981-10-25. PMID:7263381. |
depression of serotonin uptake by cultured endothelial cells exposed to high o2 tension. |
1981-10-25 |
2023-08-12 |
Not clear |
| E R Block, S A Stalcu. Depression of serotonin uptake by cultured endothelial cells exposed to high O2 tension. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 50. issue 6. 1981-10-25. PMID:7263381. |
to characterized the cellular basis and mechanism for hyperoxic depression of lung 5-ht uptake, we evaluated the effect of high po2 on 5-ht uptake by calf aortic endothelial cells in primary confluent monolayer. |
1981-10-25 |
2023-08-12 |
Not clear |
| E R Block, S A Stalcu. Depression of serotonin uptake by cultured endothelial cells exposed to high O2 tension. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 50. issue 6. 1981-10-25. PMID:7263381. |
exposure to 95% o2 for 20 h or 42 h resulted in significant depression of 5-ht uptake by cultured endothelial cells, and uptakes remained significantly depressed 48 h after exposure to 95% o2 had ended. |
1981-10-25 |
2023-08-12 |
Not clear |
| E R Block, S A Stalcu. Depression of serotonin uptake by cultured endothelial cells exposed to high O2 tension. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 50. issue 6. 1981-10-25. PMID:7263381. |
these results indicate that 1) high po2 levels depress 5-ht uptake in endothelial cells by direct inhibition of the transcellular transport of 5-ht and 2) hyperoxic depression of 5-ht uptake in cultured endothelial cells is not readily reversible. |
1981-10-25 |
2023-08-12 |
Not clear |
| D Male. Central action of narcotic analgesics. VI. Further studies on the participation of serotonin in the action of analgesics. Polish journal of pharmacology and pharmacy. vol 32. issue 5. 1981-10-14. PMID:6115369. |
depression of the cerebral level of 5-ht usually antagonized the behavioral effects of analgesics, but the effect varied with the agent depressing the 5-ht level. |
1981-10-14 |
2023-08-12 |
rat |
| B Morgan, M Winic. A possible control of food intake during pregnancy in the rat. The British journal of nutrition. vol 46. issue 1. 1981-10-14. PMID:7260030. |
the increase food intake of the dams during gestation and lactation increased to the same extent as elevation in hypothalamic norepinephrine content and depression in serotonin content. |
1981-10-14 |
2023-08-12 |
rat |
| R Philo, R J Reite. The involvement of brain amines in pinealectomy-induced convulsions in the gerbil: I. Serotonin. Behavioural brain research. vol 3. issue 1. 1981-09-15. PMID:6972773. |
serotonin is apparently of little importance in the px-induced convulsion since the artificial elevation by administration of tryptophan and 5-hydroxytryptophan, or depression by treatment with p-chloramphetamine, of telencephalic 5-ht had little effect on the convulsions. |
1981-09-15 |
2023-08-12 |
Not clear |
| S Greenberg, C McGowan, T M Glen. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. The American journal of physiology. vol 241. issue 1. 1981-08-27. PMID:7246787. |
the depression in the sensitivity to 5-ht and maximal tension development to 5-ht and ne was selective, since the responses to potassium ion were not depressed. |
1981-08-27 |
2023-08-12 |
Not clear |
| R S Jone. In vivo pharmacological studies on the interactions between tryptamine and 5-hydroxytryptamine. British journal of pharmacology. vol 73. issue 2. 1981-08-20. PMID:6972243. |
4 5-ht or noradrenaline injected intravenously into 5 day-old chicks caused a dose-dependent behavioural depression resembling sleep. |
1981-08-20 |
2023-08-12 |
mouse |