| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R S Jone. Enhancement of 5-hydroxytryptamine-induced behavioral effects following chronic administration of antidepressant drugs. Psychopharmacology. vol 69. issue 3. 1980-11-25. PMID:6774372. |
imipramine, desipramine, amitryptiline, pizotifen, and mianserin given 30 min before 5-ht all reduced the duration of 5-ht-induced behavioral depression. |
1980-11-25 |
2023-08-12 |
rat |
| H M van Praag, S de Haa. Central serotonin metabolism and frequency of depression. Psychiatry research. vol 1. issue 3. 1980-11-24. PMID:95233. |
central serotonin metabolism and frequency of depression. |
1980-11-24 |
2023-08-11 |
Not clear |
| H M van Praag, S de Haa. Central serotonin metabolism and frequency of depression. Psychiatry research. vol 1. issue 3. 1980-11-24. PMID:95233. |
central serotonin (5-hydroxytryptamine; 5-ht) metabolism can be disturbed in a subgroup of patients with vital (endogenous, primary) depression. |
1980-11-24 |
2023-08-11 |
Not clear |
| H M van Praag, S de Haa. Central serotonin metabolism and frequency of depression. Psychiatry research. vol 1. issue 3. 1980-11-24. PMID:95233. |
first, in a majority of patients, the 5-ht disturbances persist after depression has abated. |
1980-11-24 |
2023-08-11 |
Not clear |
| H M van Praag, S de Haa. Central serotonin metabolism and frequency of depression. Psychiatry research. vol 1. issue 3. 1980-11-24. PMID:95233. |
in this study we approached the hypothesis that 5-ht disturbances are a predisposing factor to the occurrence of depression from still another perspective. |
1980-11-24 |
2023-08-11 |
Not clear |
| H M van Praag, S de Haa. Central serotonin metabolism and frequency of depression. Psychiatry research. vol 1. issue 3. 1980-11-24. PMID:95233. |
if this hypothesis is correct, then depressive patients with persistent 5-ht disturbances should have higher frequencies of depression than depressive patients without demonstrable 5-ht disturbances. |
1980-11-24 |
2023-08-11 |
Not clear |
| R A Mueller, D Lundberg, G R Brees. Evidence that respiratory depression by serotonin agonists may be exerted in the central nervous system. Pharmacology, biochemistry, and behavior. vol 13. issue 2. 1980-11-24. PMID:6968074. |
evidence that respiratory depression by serotonin agonists may be exerted in the central nervous system. |
1980-11-24 |
2023-08-12 |
rat |
| G B Kaskey, S Nasr, H Y Meltze. Drug treatment in delusional depression. Psychiatry research. vol 2. issue 3. 1980-11-20. PMID:6106255. |
the clinical superiority of neuroleptics plus tca in the treatment of delusionally depressed patients suggests the possible role of dopamine in the psychosis associated with depression and implicates norepinephrine and serotonin in the disordered locomotor activity and mood of primary depressive illness. |
1980-11-20 |
2023-08-12 |
Not clear |
| E G Bliznako. Serotonin and its precursors as modulators of the immunological responsiveness in mice. Journal of medicine. vol 11. issue 2-3. 1980-11-20. PMID:6967931. |
multiple administration of 5-hydroxytryptamine(serotonin) or its precursor, 5-hydroxy-l-tryptophan(5-htph), produces marked depression of t cell dependent, humoral, hemolytic, primary immune response in mice. |
1980-11-20 |
2023-08-12 |
mouse |
| E G Bliznako. Serotonin and its precursors as modulators of the immunological responsiveness in mice. Journal of medicine. vol 11. issue 2-3. 1980-11-20. PMID:6967931. |
l-tryptophan, a more distant serotonin precursor, produces slight but significant depression of this immune response. |
1980-11-20 |
2023-08-12 |
mouse |
| A B Fisher, E R Block, G Pietr. Environmental influences on uptake of serotonin and other amines. Environmental health perspectives. vol 35. 1980-11-20. PMID:7408797. |
the results indicate that exposure to elevatd po2 results in reversible depression of pulmonary 5-ht clearance that is potentiated by vitamin e deficiency. |
1980-11-20 |
2023-08-12 |
rat |
| P K Rudeen, R J Reite. Depression of nocturnal pineal serotonin N-acetyltransferase activity in castrate male rats. Journal of neural transmission. vol 48. issue 1. 1980-11-20. PMID:7411133. |
depression of nocturnal pineal serotonin n-acetyltransferase activity in castrate male rats. |
1980-11-20 |
2023-08-12 |
rat |
| H M van Praag, S de Haa. Central serotonin deficiency--a factor which increases depression vulnerability? Acta psychiatrica Scandinavica. Supplementum. vol 280. 1980-10-24. PMID:6157306. |
central serotonin deficiency--a factor which increases depression vulnerability? |
1980-10-24 |
2023-08-12 |
Not clear |
| G E Isom, M J Meldru. Morphine induced respiratory depression: involvement of norepinephrine and serotonin. Proceedings of the Western Pharmacology Society. vol 23. 1980-10-24. PMID:7403171. |
morphine induced respiratory depression: involvement of norepinephrine and serotonin. |
1980-10-24 |
2023-08-12 |
Not clear |
| A Coppen, K Woo. [Indoleamine precursors in depression (author's transl)]. L'Encephale. vol 5. issue 5 Suppl. 1980-09-28. PMID:95009. |
there is also evidence that tryptophan and 5-ht transported are abnormal in depression. |
1980-09-28 |
2023-08-11 |
human |
| M Davis, D I Strachan, E Kas. Excitatory and inhibitory effects of serotonin on sensorimotor reactivity measured with acoustic startle. Science (New York, N.Y.). vol 209. issue 4455. 1980-09-26. PMID:7394520. |
serotonin infused into the lateral ventricle in rats produced a dose-dependent depression of the acoustic startle reflex. |
1980-09-26 |
2023-08-12 |
rat |
| R S Ehsanulla. Uptake of 5-hydroxytryptamine and dopamine into platelets from depressed patients and normal subjects--influence of clomipramine, desmethylclomipramine and maprotiline. Postgraduate medical journal. vol 56 Suppl 1. 1980-09-23. PMID:7393826. |
platelet uptake of 5-ht and da in both types of depression is lower than in healthy, which supports the hypothesis that central monamine function is reduced or impaired in depressives. |
1980-09-23 |
2023-08-12 |
human |
| M Miśkiewicz, A Rokosz-Pelc, J Vetulan. The effect of quipazine and LSD on monoamines in the rat striatum. Polish journal of pharmacology and pharmacy. vol 31. issue 5. 1980-08-25. PMID:94944. |
lsd at the peak of its action depressed the level of 5-hiaa, and in the next period produced a significant depression of striatal levels of na, 5ht and 5-hiaa. |
1980-08-25 |
2023-08-11 |
rat |
| H M van Praa. [Central serotonin metabolism in depression]. Nederlands tijdschrift voor geneeskunde. vol 124. issue 24. 1980-08-25. PMID:6966766. |
[central serotonin metabolism in depression]. |
1980-08-25 |
2023-08-12 |
Not clear |
| J M Woo. Effect of depletion of brain 5-hydroxytryptamine by 5,7-dihydroxytryptamine on ethanol tolerance and dependence in the rat. Psychopharmacology. vol 67. issue 1. 1980-06-16. PMID:6768080. |
depletion of brain 5-ht by 5,7-dht appears to result in a non-specific central nervous system depression that potentiates the depressant actions of ethanol and pentobarbitone and antagonises the hyperexcitability of ethanol withdrawal. |
1980-06-16 |
2023-08-12 |
rat |