| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Moussaou. [Biochemistry of depression. Literature analysis]. L'Encephale. vol 4. issue 3. 1979-01-26. PMID:30616. |
beyond all existing contradictory results, a review of the main works in this field enables us to point out some leading ideas:--depression would be due to and/or accompanied by a monoaminergic deficiency: some authors emphasize the serotonin one, others the noradrenaline one.--the regulation of mood most probably finds its origin in the monoaminergic balance, rather than in the gross rates of any particular monoamine.--disturbances are to be found on all metabolic levels: monoaminergic, hydroelectrolytic, hormonal, glucidic, lipidic, lipidic... close intrication exists between those different metabolisms.--the interaction between the different aminergic systems and the metabolic ways, as well as the dispersion of the acknowledged results, impose more and more the necessity of a biochemical typology of depression, which would lead to a predictive approach to the evolution and treatment of depressive illness. |
1979-01-26 |
2023-08-11 |
Not clear |
| L M Jordan, D R Kenshalo, F R Martin, L H Haber, W D Willi. Depression of primate spinothalamic tract neurons by iontophoretic application of 5-hydroxytryptamine. Pain. vol 5. issue 2. 1978-11-29. PMID:99715. |
depression of primate spinothalamic tract neurons by iontophoretic application of 5-hydroxytryptamine. |
1978-11-29 |
2023-08-11 |
monkey |
| E R Bloc. Recovery from hyperoxic depression of pulmonary 5-hydroxytryptamine clearance: effect of inspired O2 tension. Lung. vol 155. issue 2. 1978-09-25. PMID:672255. |
recovery from hyperoxic depression of pulmonary 5-hydroxytryptamine clearance: effect of inspired o2 tension. |
1978-09-25 |
2023-08-11 |
Not clear |
| A Wirz-Justice, W Pühringe. Seasonal incidence of an altered diurnal rhythm of platelet serotonin in unipolar depression. Journal of neural transmission. vol 42. issue 1. 1978-06-28. PMID:565390. |
seasonal incidence of an altered diurnal rhythm of platelet serotonin in unipolar depression. |
1978-06-28 |
2023-08-11 |
Not clear |
| A Wirz-Justice, W Pühringe. Increased platelet serotonin in bipolar depression and hypomania. Journal of neural transmission. vol 42. issue 1. 1978-06-28. PMID:565391. |
increased platelet serotonin in bipolar depression and hypomania. |
1978-06-28 |
2023-08-11 |
Not clear |
| A Wirz-Justice, W Pühringe. Increased platelet serotonin in bipolar depression and hypomania. Journal of neural transmission. vol 42. issue 1. 1978-06-28. PMID:565391. |
a longitudinal study of a bipolar ii patient throughout three hospitalizations for depression followed by the switch into hypomania, indicated that 5-ht was state independent, remaining constantly high in all clinical conditions and upon remission, reduced only during and after treatment with clomipramine, a 5-ht uptakt dysfunction of indoleamines underlying bipolar illness. |
1978-06-28 |
2023-08-11 |
Not clear |
| C M Bank. 5-Hydroxytryptamine content of the whole blood in psychiatric illness and alcoholism. Acta psychiatrica Scandinavica. vol 57. issue 3. 1978-06-12. PMID:645413. |
neuroleptic drugs in mania did not alter the blood 5ht levels, but in depression tricyclic antidepressants caused an elevation after 3 weeks of treatment. |
1978-06-12 |
2023-08-11 |
Not clear |
| K Mitsunob. [Depression and serotonin metabolism]. Nihon rinsho. Japanese journal of clinical medicine. vol 36. issue 1. 1978-05-24. PMID:416250. |
[depression and serotonin metabolism]. |
1978-05-24 |
2023-08-11 |
Not clear |
| A R Green, D G Grahame-Smit. Processes regulating the functional activity of brain 5-hydroxytryptamine: results of animal experimentation and their relevance to the understanding and treatment of depression. Pharmakopsychiatrie, Neuro-Psychopharmakologie. vol 11. issue 1. 1978-05-08. PMID:565059. |
processes regulating the functional activity of brain 5-hydroxytryptamine: results of animal experimentation and their relevance to the understanding and treatment of depression. |
1978-05-08 |
2023-08-11 |
rat |
| A R Green, D G Grahame-Smit. Processes regulating the functional activity of brain 5-hydroxytryptamine: results of animal experimentation and their relevance to the understanding and treatment of depression. Pharmakopsychiatrie, Neuro-Psychopharmakologie. vol 11. issue 1. 1978-05-08. PMID:565059. |
investigation has been made into the processes regulating the function activity of rat brain 5-hydroxytryptamine (5-ht) and the way that drugs used to treat depression act on these processes. |
1978-05-08 |
2023-08-11 |
rat |
| D A Cook, K M Macleo. Responses of rabbit portal vein to histamine. British journal of pharmacology. vol 62. issue 2. 1978-04-17. PMID:23880. |
4 desensitization to high doses of 5-hydroxytryptamine caused a concomitant depression in the response to histamine but not to noradrenaline or acetylcholine. |
1978-04-17 |
2023-08-11 |
rabbit |
| M Smialowsk. Nomifensine and central monoamine neurons: histofluorescence studies. Polish journal of pharmacology and pharmacy. vol 29. issue 5. 1978-02-18. PMID:145591. |
the effect of nomifensine (nf) on the content of serotonin (5-ht) and catecholamines (ca) in discrete regions of rat brain was studied with the histofluorescence technique of falck, nf, 20 and 40 mg/kg ip, produced, after 30 min, a depression of 5-ht content in the neurocytes of dorsal and median raphe nuclei (ndr and nmr). |
1978-02-18 |
2023-08-11 |
rat |
| P L Nola. The effects of serotonin precursors on the pressor response to intravenous clonidine in conscious rats. Clinical and experimental pharmacology & physiology. vol 4. issue 6. 1978-02-18. PMID:303969. |
the depression by l-tryptophan of the clonidine-induced pressor response could be prevented by pretreatment with either the l-aromatic amino acid decarboxylase inhibitor rö44602 or the serotonin antagonist methysergide. |
1978-02-18 |
2023-08-11 |
rat |
| D N Franz, R J Neumayr, B D Har. L-dopa-induced hypotension: depression of spinal sympathetic neurons by release of 5-hydroxytryptamine. Advances in experimental medicine and biology. vol 90. 1978-01-27. PMID:201160. |
l-dopa-induced hypotension: depression of spinal sympathetic neurons by release of 5-hydroxytryptamine. |
1978-01-27 |
2023-08-11 |
Not clear |
| R G Schaub, K M Meyers, R D Sand. Serotonin as a factor in depression of collateral blood flow following experimental arterial thrombosis. The Journal of laboratory and clinical medicine. vol 90. issue 4. 1977-11-25. PMID:143502. |
serotonin as a factor in depression of collateral blood flow following experimental arterial thrombosis. |
1977-11-25 |
2023-08-11 |
Not clear |
| A Randrup, C Braestru. Uptake inhibition of biogenic amines by newer antidepressant drugs: relevance to the dopamine hypothesis of depression. Psychopharmacology. vol 53. issue 3. 1977-10-31. PMID:408861. |
the dopamine theory of depression was studied by assessing the effect of antidepressant drugs on uptake of dopamine, noradrenaline, and serotonin in synaptosomes from rat brain. |
1977-10-31 |
2023-08-11 |
rat |
| A Dray, N R Oakle. Methiothepin and a 5-HT pathway to rat substantia nigra. Experientia. vol 33. issue 9. 1977-10-31. PMID:891876. |
methiothepin reduced both median-raphe evoked and exogenous 5-ht depression of single substantia nigra neurones. |
1977-10-31 |
2023-08-11 |
rat |
| E R Block, A B Fishe. Effect of hyperbaric oxygen exposure on pulmonary clearance of 5-hydroxytryptamine. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 43. issue 2. 1977-10-28. PMID:893279. |
these results indicate that depression of pulmonary 5-ht clearance occurs in rats due to hyperoxia and is potentiated by vitamin e deficiency. |
1977-10-28 |
2023-08-11 |
rat |
| E R Block, A B Fishe. Prevention of hyperoxic-induced depression of pulmonary serotonin clearance by pretreatment with superoxide dismutase. The American review of respiratory disease. vol 116. issue 3. 1977-10-20. PMID:900632. |
prevention of hyperoxic-induced depression of pulmonary serotonin clearance by pretreatment with superoxide dismutase. |
1977-10-20 |
2023-08-11 |
Not clear |
| P Teerapong, A L Harve. The effect of 5-hydroxytryptamine on the chick biventer cervicis muscle. European journal of pharmacology. vol 44. issue 2. 1977-09-29. PMID:885170. |
at higher concentrations, 5ht produced a reversible depression of twitches, which was much more marked in indirectly than in directly stimulated preparations. |
1977-09-29 |
2023-08-11 |
chicken |