| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Montgomer. The benefits and risks of 5-HT uptake inhibitors in depression. The British journal of psychiatry. Supplement. issue 3. 1989-07-19. PMID:2471570. |
the benefits and risks of 5-ht uptake inhibitors in depression. |
1989-07-19 |
2023-08-11 |
Not clear |
| J T Eells, D M Wilkiso. Effects of intraocular mescaline and LSD on visual-evoked responses in the rat. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2734330. |
the serotonin receptor antagonists, cyproheptadine and methysergide, antagonized the mescaline-induced depression of the fep in accordance with neurochemical and behavioral evidence that mescaline acts as a partial agonist on serotonin receptors. |
1989-07-17 |
2023-08-11 |
rat |
| b' E V Gura, V A Iakhnitsa, Iu P Limanski\\xc4\\xa. [Role of the serotoninergic system in inhibiting the jaw-opening reflex induced by stimulation of the central gray matter of the midbrain]. Neirofiziologiia = Neurophysiology. vol 21. issue 1. 1989-07-10. PMID:2524672.' |
conclusion is made about serotonin participation in hjor depression induced by cgm and nrd stimulation. |
1989-07-10 |
2023-08-11 |
Not clear |
| P Wallén, J T Buchanan, S Grillner, R H Hill, J Christenson, T Hökfel. Effects of 5-hydroxytryptamine on the afterhyperpolarization, spike frequency regulation, and oscillatory membrane properties in lamprey spinal cord neurons. Journal of neurophysiology. vol 61. issue 4. 1989-07-10. PMID:2542472. |
local application of 5-hydroxytryptamine (5-ht) in the area in which a dense 5-ht plexus is located in the lamprey spinal cord leads to a marked depression of the late phase of the afterhyperpolarization (ahp) following the action potential. |
1989-07-10 |
2023-08-11 |
Not clear |
| A Baskys, C E Niesen, M F Davies, P L Carle. Modulatory actions of serotonin on ionic conductances of hippocampal dentate granule cells. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2471114. |
the slow time course of the late depolarization and the afterhyperpolarization depression represent modulatory effects of serotonin on dentate granule neurons. |
1989-07-07 |
2023-08-11 |
Not clear |
| G D Tollefso. Serotonin and alcohol: interrelationships. Psychopathology. vol 22 Suppl 1. 1989-07-03. PMID:2567040. |
such altered characteristics of 5-ht secondary to chronic alcohol use may explain the frequent morbidity of anxiety and/or depression. |
1989-07-03 |
2023-08-11 |
Not clear |
| M Bugge, F Bengtsson, A Nobin, B Jeppsson, B Hultberg, T Jonung, P Herli. The effect of ammonia infusion on brain monoamine metabolism in portacaval-shunted rats. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 189. issue 2. 1989-06-27. PMID:2471238. |
the study suggests that hyperammonemia in pcs rats results in a depression of the serotonin synthesis rate in accordance with two previous studies but in contrast to previous hypotheses on the regulation of serotonin metabolism. |
1989-06-27 |
2023-08-11 |
rat |
| P D Hrdin. Imipramine binding sites in brain and platelets: role in affective disorders. International journal of clinical pharmacology research. vol 9. issue 2. 1989-06-22. PMID:2541089. |
[3h]paroxetine) should be used in future studies of serotonin transporter function in depression. |
1989-06-22 |
2023-08-11 |
human |
| R P Heinsbroek, M G Feenstra, P Boon, F Van Haaren, N E Van de Pol. Sex differences in passive avoidance depend on the integrity of the central serotonergic system. Pharmacology, biochemistry, and behavior. vol 31. issue 2. 1989-06-06. PMID:2469088. |
these data are indicative of a strong and selective depression of the central 5-ht activity. |
1989-06-06 |
2023-08-11 |
human |
| C M Hart, E R Bloc. Lung serotonin metabolism. Clinics in chest medicine. vol 10. issue 1. 1989-06-01. PMID:2650964. |
in addition, depression of 5-ht uptake can lead to increased concentrations of 5-ht in the pulmonary vasculature, which may contribute to the pathogenesis of lung injury. |
1989-06-01 |
2023-08-11 |
human |
| M Q Paiva, M M Caramona, W Osswal. The actions of 5-hydroxytryptamine receptor agonists and antagonists at pre- and postjunctional level on the canine saphenous vein. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:2977424. |
the contractions caused by 5-ht were antagonized by metitepine and yohimbine (parallel displacement of the curves to the right), as well as by ketanserin and methysergide (with a depression of the upper part of the curve). |
1989-05-31 |
2023-08-11 |
dog |
| R Malmgren, A Aberg-Wistedt, B Mårtensso. Aberrant seasonal variations of platelet serotonin uptake in endogenous depression. Biological psychiatry. vol 25. issue 4. 1989-05-19. PMID:2930808. |
aberrant seasonal variations of platelet serotonin uptake in endogenous depression. |
1989-05-19 |
2023-08-11 |
human |
| R B Lydiard, K T Brady, P M O'Neil, B Schlesier-Carter, S Hamilton, Q Rogers, J C Ballenge. Precursor amino acid concentrations in normal weight bulimics and normal controls. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 6. 1989-05-16. PMID:3241872. |
reduced availability of tryptophan for conversion to serotonin is not likely to be the postulated biological abnormality common to both depression and bulimia. |
1989-05-16 |
2023-08-11 |
human |
| H M Pappiu. Significance of biogenic amines in functional disturbances resulting from brain injury. Metabolic brain disease. vol 3. issue 4. 1989-05-12. PMID:2977213. |
pcpa at doses which selectively ameliorated the depression of cortical lcgu in the lesioned hemisphere (200 and 300 mg/kg) completely prevented changes in 5-ht and 5-hydroxyindoleacetic acid seen following traumatization in untreated animals. |
1989-05-12 |
2023-08-11 |
rat |
| T A Slotkin, W L Whitmore, G A Barnes, K R Krishnan, D G Blazer, D L Knight, C B Nemerof. Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. Biological psychiatry. vol 25. issue 6. 1989-05-05. PMID:2538161. |
reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. |
1989-05-05 |
2023-08-11 |
human |
| T A Slotkin, W L Whitmore, G A Barnes, K R Krishnan, D G Blazer, D L Knight, C B Nemerof. Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. Biological psychiatry. vol 25. issue 6. 1989-05-05. PMID:2538161. |
tritiated imipramine binding, uptake of radiolabeled serotonin, and inhibition of uptake by imipramine in vitro were studied in platelets obtained from four groups of subjects: (1) normal controls 50 years of age or younger, (2) patients with major depression 50 years of age or younger, (3) normal controls 60 years of age or older, and (4) patients with major depression 60 years of age or older. |
1989-05-05 |
2023-08-11 |
human |
| T A Slotkin, W L Whitmore, G A Barnes, K R Krishnan, D G Blazer, D L Knight, C B Nemerof. Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. Biological psychiatry. vol 25. issue 6. 1989-05-05. PMID:2538161. |
depression in both age groups was associated with a substantial decrease in the number of [3h]imipramine binding sites; the elderly depressed patients exhibited a small but significant (p less than 0.05) reduction in platelet [3h]serotonin uptake. |
1989-05-05 |
2023-08-11 |
human |
| H E Connor, W Feniuk, P P Humphre. Characterization of 5-HT receptors mediating contraction of canine and primate basilar artery by use of GR43175, a selective 5-HT1-like receptor agonist. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2538191. |
in canine basilar artery, ketanserin (0.1-1 microm) caused some depression of the maximum effect of 5-ht but produced little or no shift of the concentration-effect curve. |
1989-05-05 |
2023-08-11 |
Not clear |
| H E Connor, W Feniuk, P P Humphre. Characterization of 5-HT receptors mediating contraction of canine and primate basilar artery by use of GR43175, a selective 5-HT1-like receptor agonist. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2538191. |
in primate basilar artery, ketanserin (1 microm) again caused a small depression of the 5-ht maximum response but had not effect against gr43175-induced contractions. |
1989-05-05 |
2023-08-11 |
Not clear |
| G A Higgins, A J Bradbury, B J Jones, N R Oakle. Behavioural and biochemical consequences following activation of 5HT1-like and GABA receptors in the dorsal raphé nucleus of the rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:2467224. |
these findings, together with available electrophysiological data suggest that these behavioural responses are a consequence of a depression of the firing of cells in the dorsal raphé nucleus, with a corresponding decrease in functional activity of 5-ht in the forebrain. |
1989-05-02 |
2023-08-11 |
rat |