| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Curzo. 5-Hydroxytryptamine and corticosterone in an animal model of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 13. issue 3-4. 1989-08-21. PMID:2748869. |
failure to adapt is the depression model which is associated with three factors implicated in the illness ie increased plasma glucocorticoid level, female sex and inadequate 5-ht function as revealed by behavioural response to the agonist 5-methoxy-n,n-dimethyl 5-ht. |
1989-08-21 |
2023-08-11 |
rat |
| Y Ohno, J E Warnic. Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro. The Journal of pharmacology and experimental therapeutics. vol 250. issue 1. 1989-08-11. PMID:2746496. |
the depression of the monosynaptic reflex by pcp was antagonized by serotonin (5-ht) receptor antagonists (methiothepin, spiperone and ketanserin) but unaffected by noradrenergic (phentolamine and timolol), dopaminergic (chlorpromazine and pimozide) and cholinergic antagonists (atropine and mecamylamine). |
1989-08-11 |
2023-08-11 |
rat |
| Y Ohno, J E Warnic. Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro. The Journal of pharmacology and experimental therapeutics. vol 250. issue 1. 1989-08-11. PMID:2746496. |
furthermore, pretreatment of rats with desipramine and 5,7-dihydroxytryptamine largely diminished the depression of the monosynaptic reflex by pcp and p-chloroamphetamine while enhancing the depressant action of 5-ht. |
1989-08-11 |
2023-08-11 |
rat |
| J C Pecknold, B Suranyi-Cadotte, H Chang, N P Nai. Serotonin uptake in panic disorder and agoraphobia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 1. issue 2. 1989-08-03. PMID:3251498. |
because of reports of reduced serotonin uptake in depression and the frequent association between panic disorder and depression, this study was designed to assess the neurobiologic relationship between panic disorder and depression. |
1989-08-03 |
2023-08-11 |
human |
| A B Katasonow, O S Brusow, B S Beljaew, G P Slobina, M I Faktor, T B Larionowa, K Trunte, R R Lideman. [The effect of imipramine and trazodone on the re-uptake of (3H) serotonin by thrombocytes in patients with endogenous depression: changes in antidepressive therapy]. Psychiatrie, Neurologie, und medizinische Psychologie. vol 41. issue 4. 1989-08-01. PMID:2544916. |
[the effect of imipramine and trazodone on the re-uptake of (3h) serotonin by thrombocytes in patients with endogenous depression: changes in antidepressive therapy]. |
1989-08-01 |
2023-08-11 |
Not clear |
| S A Montgomer. The benefits and risks of 5-HT uptake inhibitors in depression. The British journal of psychiatry. Supplement. issue 3. 1989-07-19. PMID:2471570. |
the benefits and risks of 5-ht uptake inhibitors in depression. |
1989-07-19 |
2023-08-11 |
Not clear |
| J T Eells, D M Wilkiso. Effects of intraocular mescaline and LSD on visual-evoked responses in the rat. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2734330. |
the serotonin receptor antagonists, cyproheptadine and methysergide, antagonized the mescaline-induced depression of the fep in accordance with neurochemical and behavioral evidence that mescaline acts as a partial agonist on serotonin receptors. |
1989-07-17 |
2023-08-11 |
rat |
| b' E V Gura, V A Iakhnitsa, Iu P Limanski\\xc4\\xa. [Role of the serotoninergic system in inhibiting the jaw-opening reflex induced by stimulation of the central gray matter of the midbrain]. Neirofiziologiia = Neurophysiology. vol 21. issue 1. 1989-07-10. PMID:2524672.' |
conclusion is made about serotonin participation in hjor depression induced by cgm and nrd stimulation. |
1989-07-10 |
2023-08-11 |
Not clear |
| P Wallén, J T Buchanan, S Grillner, R H Hill, J Christenson, T Hökfel. Effects of 5-hydroxytryptamine on the afterhyperpolarization, spike frequency regulation, and oscillatory membrane properties in lamprey spinal cord neurons. Journal of neurophysiology. vol 61. issue 4. 1989-07-10. PMID:2542472. |
local application of 5-hydroxytryptamine (5-ht) in the area in which a dense 5-ht plexus is located in the lamprey spinal cord leads to a marked depression of the late phase of the afterhyperpolarization (ahp) following the action potential. |
1989-07-10 |
2023-08-11 |
Not clear |
| A Baskys, C E Niesen, M F Davies, P L Carle. Modulatory actions of serotonin on ionic conductances of hippocampal dentate granule cells. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2471114. |
the slow time course of the late depolarization and the afterhyperpolarization depression represent modulatory effects of serotonin on dentate granule neurons. |
1989-07-07 |
2023-08-11 |
Not clear |
| G D Tollefso. Serotonin and alcohol: interrelationships. Psychopathology. vol 22 Suppl 1. 1989-07-03. PMID:2567040. |
such altered characteristics of 5-ht secondary to chronic alcohol use may explain the frequent morbidity of anxiety and/or depression. |
1989-07-03 |
2023-08-11 |
Not clear |
| M Bugge, F Bengtsson, A Nobin, B Jeppsson, B Hultberg, T Jonung, P Herli. The effect of ammonia infusion on brain monoamine metabolism in portacaval-shunted rats. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 189. issue 2. 1989-06-27. PMID:2471238. |
the study suggests that hyperammonemia in pcs rats results in a depression of the serotonin synthesis rate in accordance with two previous studies but in contrast to previous hypotheses on the regulation of serotonin metabolism. |
1989-06-27 |
2023-08-11 |
rat |
| P D Hrdin. Imipramine binding sites in brain and platelets: role in affective disorders. International journal of clinical pharmacology research. vol 9. issue 2. 1989-06-22. PMID:2541089. |
[3h]paroxetine) should be used in future studies of serotonin transporter function in depression. |
1989-06-22 |
2023-08-11 |
human |
| R P Heinsbroek, M G Feenstra, P Boon, F Van Haaren, N E Van de Pol. Sex differences in passive avoidance depend on the integrity of the central serotonergic system. Pharmacology, biochemistry, and behavior. vol 31. issue 2. 1989-06-06. PMID:2469088. |
these data are indicative of a strong and selective depression of the central 5-ht activity. |
1989-06-06 |
2023-08-11 |
human |
| C M Hart, E R Bloc. Lung serotonin metabolism. Clinics in chest medicine. vol 10. issue 1. 1989-06-01. PMID:2650964. |
in addition, depression of 5-ht uptake can lead to increased concentrations of 5-ht in the pulmonary vasculature, which may contribute to the pathogenesis of lung injury. |
1989-06-01 |
2023-08-11 |
human |
| M Q Paiva, M M Caramona, W Osswal. The actions of 5-hydroxytryptamine receptor agonists and antagonists at pre- and postjunctional level on the canine saphenous vein. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:2977424. |
the contractions caused by 5-ht were antagonized by metitepine and yohimbine (parallel displacement of the curves to the right), as well as by ketanserin and methysergide (with a depression of the upper part of the curve). |
1989-05-31 |
2023-08-11 |
dog |
| R Malmgren, A Aberg-Wistedt, B Mårtensso. Aberrant seasonal variations of platelet serotonin uptake in endogenous depression. Biological psychiatry. vol 25. issue 4. 1989-05-19. PMID:2930808. |
aberrant seasonal variations of platelet serotonin uptake in endogenous depression. |
1989-05-19 |
2023-08-11 |
human |
| R B Lydiard, K T Brady, P M O'Neil, B Schlesier-Carter, S Hamilton, Q Rogers, J C Ballenge. Precursor amino acid concentrations in normal weight bulimics and normal controls. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 6. 1989-05-16. PMID:3241872. |
reduced availability of tryptophan for conversion to serotonin is not likely to be the postulated biological abnormality common to both depression and bulimia. |
1989-05-16 |
2023-08-11 |
human |
| H M Pappiu. Significance of biogenic amines in functional disturbances resulting from brain injury. Metabolic brain disease. vol 3. issue 4. 1989-05-12. PMID:2977213. |
pcpa at doses which selectively ameliorated the depression of cortical lcgu in the lesioned hemisphere (200 and 300 mg/kg) completely prevented changes in 5-ht and 5-hydroxyindoleacetic acid seen following traumatization in untreated animals. |
1989-05-12 |
2023-08-11 |
rat |
| T A Slotkin, W L Whitmore, G A Barnes, K R Krishnan, D G Blazer, D L Knight, C B Nemerof. Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. Biological psychiatry. vol 25. issue 6. 1989-05-05. PMID:2538161. |
reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression. |
1989-05-05 |
2023-08-11 |
human |