| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D C Jimerson, M D Lesem, W H Kaye, A P Hegg, T D Brewerto. Eating disorders and depression: is there a serotonin connection? Biological psychiatry. vol 28. issue 5. 1990-11-06. PMID:2207221. |
eating disorders and depression: is there a serotonin connection? |
1990-11-06 |
2023-08-11 |
Not clear |
| D C Jimerson, M D Lesem, W H Kaye, A P Hegg, T D Brewerto. Eating disorders and depression: is there a serotonin connection? Biological psychiatry. vol 28. issue 5. 1990-11-06. PMID:2207221. |
this review compares evidence for alterations in central serotonin regulation in patients with anorexia nervosa, bulimia nervosa, and depression. |
1990-11-06 |
2023-08-11 |
Not clear |
| D C Jimerson, M D Lesem, W H Kaye, A P Hegg, T D Brewerto. Eating disorders and depression: is there a serotonin connection? Biological psychiatry. vol 28. issue 5. 1990-11-06. PMID:2207221. |
it is proposed that impaired synaptic transmission in functionally distinct serotonin pathways may result in concurrent or sequential periods of binge eating, behavioral impulsivity, and depression in patients with eating disorders. |
1990-11-06 |
2023-08-11 |
Not clear |
| R G Dudle. Serotonin partial agonists in the treatment of anxiety and depression. Introduction. The Journal of clinical psychiatry. vol 51 Suppl. 1990-11-06. PMID:2211563. |
serotonin partial agonists in the treatment of anxiety and depression. |
1990-11-06 |
2023-08-11 |
Not clear |
| E Dimitrio. Serotonin partial agonists in the treatment of depression. The Journal of clinical psychiatry. vol 51 Suppl. 1990-11-06. PMID:2211573. |
serotonin partial agonists in the treatment of depression. |
1990-11-06 |
2023-08-11 |
Not clear |
| R S Nathan, J M Perel, B G Pollock, D J Kupfe. The role of neuropharmacologic selectivity in antidepressant action: fluvoxamine versus desipramine. The Journal of clinical psychiatry. vol 51. issue 9. 1990-11-01. PMID:2120201. |
the authors found a positive relationship between hamilton rating scale for depression scores and norepinephrine uptake inhibition for desipramine but found no such relationship between fluvoxamine and serotonin uptake inhibition. |
1990-11-01 |
2023-08-11 |
Not clear |
| Zh A Kruchenko, V V Sachenk. [The effect of the selective blocking of synaptic transmission in the parafascicular complex on the neuronal activity of the sensorimotor cortex]. Neirofiziologiia = Neurophysiology. vol 22. issue 3. 1990-10-18. PMID:2169030. |
it is shown that an increase in the background activity of neurons of the sensorimotor cortex was caused by microinjections of obsidan, an adrenergic blocker, while depression--by microinjections of lysergoamid, a serotonin blocker. |
1990-10-18 |
2023-08-11 |
Not clear |
| S Barry, O M Phillips, D C Williams, T G Dina. Platelet 5-HT uptake in post-stroke depression. Acta psychiatrica Scandinavica. vol 82. issue 1. 1990-10-12. PMID:2399828. |
platelet 5-ht uptake in post-stroke depression. |
1990-10-12 |
2023-08-11 |
Not clear |
| C J Gouret, R Porsolt, J G Wettstein, A Puech, C Soulard, X Pascaud, J L Junie. Biochemical and pharmacological evaluation of the novel antidepressant and serotonin uptake inhibitor 2-(3,4-Dichlorobenzyl)-2-dimethylamino-1-propanol hydrochloride. Arzneimittel-Forschung. vol 40. issue 6. 1990-10-09. PMID:2168703. |
jo 1017 may have a potential clinical utility both in the treatment of depression and for indications where serotonin transmission is involved, e.g., anxiety, panic attack, obsessive compulsive disorder, obesity and alcohol consumption. |
1990-10-09 |
2023-08-11 |
mouse |
| S B Backman, H Sequeira-Martinho, J L Henr. Adrenal versus nonadrenal sympathetic preganglionic neurones in the lower thoracic intermediolateral nucleus of the cat: effects of serotonin, substance P, and thyrotropin-releasing hormone. Canadian journal of physiology and pharmacology. vol 68. issue 8. 1990-10-04. PMID:1697219. |
depression was never observed and responses were similar whether using serotonin at a ph of 3.3 or 4.5, suggesting that the absence of a depressant effect cannot be accounted for by ph, as has been reported with cortical neurones. |
1990-10-04 |
2023-08-11 |
cat |
| Y Dua. [Thyrotrophin-releasing hormone (TRH) stimulation test in psychiatric patients]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry. vol 23. issue 2. 1990-10-04. PMID:2118064. |
these results seemed to support the view that trh stimulation test can be used as a biological marker to distinguish affective disorder and that both depression and mania is correlated with the decreased function of serotonin. |
1990-10-04 |
2023-08-11 |
Not clear |
| P Elliott, B M Seemungal, D I Walli. Antagonism of the effects of 5-hydroxytryptamine on the rabbit isolated vagus nerve by BRL 43694 and metoclopramide. Naunyn-Schmiedeberg's archives of pharmacology. vol 341. issue 6. 1990-10-04. PMID:2168021. |
at the highest concentration of antagonist, there was some depression of the maximal 5-ht response. |
1990-10-04 |
2023-08-11 |
rabbit |
| A Biegon, N Essar, M Israeli, A Elizur, S Bruch, A A Bar-Natha. Serotonin 5-HT2 receptor binding on blood platelets as a state dependent marker in major affective disorder. Psychopharmacology. vol 102. issue 1. 1990-10-04. PMID:2392511. |
serotonin receptors of the 5-ht2 type were studied on platelet membranes from 15 patients suffering from major depression. |
1990-10-04 |
2023-08-11 |
Not clear |
| D J Horrigan, J M Horowit. Thermal dependence of serotonergic modulation of neural activity in the hamster. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology. vol 167. issue 1. 1990-09-24. PMID:2388182. |
thus, over the entire temperature range of 35 degrees c to 15 degrees c, serotonin exerted a dual modulatory effect on the spike amplitude, a depression followed by an enhancement. |
1990-09-24 |
2023-08-11 |
Not clear |
| F D Yocc. Neurochemistry and neurophysiology of buspirone and gepirone: interactions at presynaptic and postsynaptic 5-HT1A receptors. Journal of clinical psychopharmacology. vol 10. issue 3 Suppl. 1990-09-05. PMID:1973941. |
these results suggest that the efficacy seen in clinical trials of anxiety and depression may be related to buspirone's and gepirone's complex interaction with presynaptic and postsynaptic 5-ht1a receptors, which initiate long-term changes in central 5-ht neurotransmission. |
1990-09-05 |
2023-08-11 |
Not clear |
| M S Eiso. Serotonin: a common neurobiologic substrate in anxiety and depression. Journal of clinical psychopharmacology. vol 10. issue 3 Suppl. 1990-09-05. PMID:2198299. |
serotonin: a common neurobiologic substrate in anxiety and depression. |
1990-09-05 |
2023-08-11 |
Not clear |
| M S Eiso. Serotonin: a common neurobiologic substrate in anxiety and depression. Journal of clinical psychopharmacology. vol 10. issue 3 Suppl. 1990-09-05. PMID:2198299. |
it is proposed that imbalances in serotonergic neurotransmission may contribute significantly to both pathologies and that agents that act as serotonin partial agonists may normalize neurotransmission in both serotonin deficit (depression) and excess (anxiety) diseases. |
1990-09-05 |
2023-08-11 |
Not clear |
| D S Robinson, K Rickels, J Feighner, L F Fabre, R E Gammans, R C Shrotriya, D R Alms, J J Andary, M E Messin. Clinical effects of the 5-HT1A partial agonists in depression: a composite analysis of buspirone in the treatment of depression. Journal of clinical psychopharmacology. vol 10. issue 3 Suppl. 1990-09-05. PMID:2198303. |
buspirone, a serotonin (5-hydroxytryptamine, 5-ht) partial agonist active at the 5-ht1a receptor subtype, was evaluated in the treatment of depression in a series of five placebo-controlled, parallel group studies involving 382 patients with dsm-iii major depression and significant associated anxiety symptoms (both hamilton depression [ham-d] and hamilton anxiety [ham-a] scales greater than or equal to 18). |
1990-09-05 |
2023-08-11 |
Not clear |
| M L Rao, B Müller-Oerlinghausen, A Mackert, R D Stieglitz, B Strebel, H P Vol. The influence of phototherapy on serotonin and melatonin in non-seasonal depression. Pharmacopsychiatry. vol 23. issue 3. 1990-08-29. PMID:2374773. |
the influence of phototherapy on serotonin and melatonin in non-seasonal depression. |
1990-08-29 |
2023-08-11 |
human |
| M L Rao, B Müller-Oerlinghausen, A Mackert, R D Stieglitz, B Strebel, H P Vol. The influence of phototherapy on serotonin and melatonin in non-seasonal depression. Pharmacopsychiatry. vol 23. issue 3. 1990-08-29. PMID:2374773. |
circadian profiles of melatonin in serum and serotonin in blood were assessed before and after 7 days of artificial light treatment in 30 patients with non-seasonal depression and 12 healthy subjects. |
1990-08-29 |
2023-08-11 |
human |