| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Sarrias, E Martínez, P Celada, C Udina, E Alvarez, F Artiga. Plasma free 5HT and platelet 5HT in depression: case-control studies and the effect of antidepressant therapy. Advances in experimental medicine and biology. vol 294. 1992-02-25. PMID:1722955. |
plasma free 5ht and platelet 5ht in depression: case-control studies and the effect of antidepressant therapy. |
1992-02-25 |
2023-08-11 |
Not clear |
| H Nagayama, K Tsuchiyama, K Yamada, J Akiyosh. Animal study on the role of serotonin in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 6. 1992-02-13. PMID:1763191. |
animal study on the role of serotonin in depression. |
1992-02-13 |
2023-08-11 |
human |
| H Nagayama, K Tsuchiyama, K Yamada, J Akiyosh. Animal study on the role of serotonin in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 6. 1992-02-13. PMID:1763191. |
in our series of experiments the role of serotonin in human depression was studied by using animal models of depression. |
1992-02-13 |
2023-08-11 |
human |
| H Nagayama, K Tsuchiyama, K Yamada, J Akiyosh. Animal study on the role of serotonin in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 6. 1992-02-13. PMID:1763191. |
the results of these studies support the hypothesis that some types of human depression may be primarily due to an excessive transmission of serotonin at the synapse. |
1992-02-13 |
2023-08-11 |
human |
| P A Broderick, M F Pierce. 5-HT1A agonists uncouple noradrenergic somatodendritic impulse flow and terminal release. Brain research bulletin. vol 27. issue 5. 1992-02-06. PMID:1684526. |
in ca1 region of hippocampus, both buspirone and ipsapirone significantly depressed ne release with potencies greater than those required for the significant depression of 5-ht release. |
1992-02-06 |
2023-08-11 |
Not clear |
| I N Ferrie. Chronic depression: future prospects from recent research. International clinical psychopharmacology. vol 6 Suppl 1. 1992-02-06. PMID:1684591. |
the central role of 5ht in depression is emphasized and it seems likely that the maintenance of adequate 5ht neurotransmission is required for the treatment of chronic depression. |
1992-02-06 |
2023-08-11 |
Not clear |
| L A Hilakivi-Clark. Effects of tryptophan on depression and aggression in STZ-D mice. Diabetes. vol 40. issue 12. 1992-02-03. PMID:1756900. |
streptozocin-induced diabetic (stz-d) mice have reduced brain concentrations of tryptophan, a precursor substance for 5-hydroxytryptamine, and show lengthened immobility in porsolt's swim test, a putative animal model of depression. |
1992-02-03 |
2023-08-11 |
mouse |
| L Hernandez, M Parada, T Baptista, D Schwartz, H L West, G P Mark, B G Hoebe. Hypothalamic serotonin in treatments for feeding disorders and depression as studied by brain microdialysis. The Journal of clinical psychiatry. vol 52 Suppl. 1992-01-30. PMID:1752857. |
hypothalamic serotonin in treatments for feeding disorders and depression as studied by brain microdialysis. |
1992-01-30 |
2023-08-11 |
rat |
| F Chaoulof. [Behavioural adaptation to stress. Improvement by tianeptine]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1836614. |
the aim of this study was to analyse the behaviour effects of tianeptine, an activator of the serotonin neural recapture, in three animal models of depression: immobilization stress, acquired resignation and obligatory swimming. |
1992-01-30 |
2023-08-11 |
Not clear |
| b' D M\\xc3\\xbcck-Seler, M Jakovljevi\\xc4\\x87, Z Deanovi\\xc4\\x8. Platelet serotonin in subtypes of schizophrenia and unipolar depression. Psychiatry research. vol 38. issue 2. 1992-01-28. PMID:1754625.' |
platelet serotonin in subtypes of schizophrenia and unipolar depression. |
1992-01-28 |
2023-08-11 |
human |
| C Moret, M Brile. Platelet 3H-paroxetine binding to the serotonin transporter is insensitive to changes in central serotonergic innervation in the rat. Psychiatry research. vol 38. issue 2. 1992-01-28. PMID:1836639. |
the serotonin transporter labeled in platelets by 3h-imipramine or 3h-paroxetine binding has been suggested to be a peripheral marker for changes in serotonin uptake in the brain that may be related to depression. |
1992-01-28 |
2023-08-11 |
rat |
| J R Seckl, G Fin. Use of in situ hybridization to investigate the regulation of hippocampal corticosteroid receptors by monoamines. The Journal of steroid biochemistry and molecular biology. vol 40. issue 4-6. 1992-01-08. PMID:1659890. |
both abnormal 5-ht neurotransmission and excessive corticosteroid secretion are associated with major affective disorder, particularly depression. |
1992-01-08 |
2023-08-11 |
rat |
| P J Cowen, S L McCance, C J Ware, P R Cohen, J S Chalmers, D L Julie. Lithium in tricyclic-resistant depression. Correlation of increased brain 5-HT function with clinical outcome. The British journal of psychiatry : the journal of mental science. vol 159. 1992-01-07. PMID:1659918. |
lithium may increase brain 5-ht function in tricyclic-resistant depression but there is only limited support for the hypothesis that changes in brain 5-ht function are involved in the antidepressant effect of this treatment combination. |
1992-01-07 |
2023-08-11 |
Not clear |
| K R Krishnan, J C Ritchie, A N Manepalli, W H Wilson, W B Saunders, S S Venkataraman, B J Carrol. Role of serotonin in hypothalamo pituitary adrenal axis escape from dexamethasone suppression. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 5. 1992-01-02. PMID:1659724. |
the authors investigated the role of serotonin in the hypothalamo pituitary adrenal escape from depression. |
1992-01-02 |
2023-08-11 |
Not clear |
| S Y Wu, M Y Wang, N J Du. Serotonin via presynaptic 5-HT1 receptors attenuates synaptic transmission to immature rat motoneurons in vitro. Brain research. vol 554. issue 1-2. 1991-12-26. PMID:1681986. |
the 5-ht-induced synaptic depression was not accompanied by a concomitant reduction of glutamate-induced depolarizations; the latter were enhanced after repeated exposure to 5-ht in some motoneurons. |
1991-12-26 |
2023-08-11 |
rat |
| H Crick, D I Walli. Inhibition of reflex responses of neonate rat lumbar spinal cord by 5-hydroxytryptamine. British journal of pharmacology. vol 103. issue 3. 1991-12-18. PMID:1933139. |
neither ketanserin (1 microm) nor spiperone (1 microm) caused appreciable blockade of 5-ht depression of the msr or 5-ht depression of the psr. |
1991-12-18 |
2023-08-11 |
rat |
| H Crick, D I Walli. Inhibition of reflex responses of neonate rat lumbar spinal cord by 5-hydroxytryptamine. British journal of pharmacology. vol 103. issue 3. 1991-12-18. PMID:1933139. |
it was concluded that 5-ht has a potent depressant action on segmental reflexes; depression of the msr is unrelated to depolarization of motoneurones. |
1991-12-18 |
2023-08-11 |
rat |
| H Crick, D I Walli. Inhibition of reflex responses of neonate rat lumbar spinal cord by 5-hydroxytryptamine. British journal of pharmacology. vol 103. issue 3. 1991-12-18. PMID:1933139. |
although depression of the msr was mimicked by 5-htia receptor ligands, the action of endogenous 5-ht may be mediated through 5-ht2 receptors. |
1991-12-18 |
2023-08-11 |
rat |
| R D Blakely, H E Berson, R T Fremeau, M G Caron, M M Peek, H K Prince, C C Bradle. Cloning and expression of a functional serotonin transporter from rat brain. Nature. vol 354. issue 6348. 1991-12-11. PMID:1944572. |
uptake and/or transport sites of 5ht have been reported to be reduced in platelets of patients suffering from depression and in post-mortem brain samples of depressed patients and suicide victims. |
1991-12-11 |
2023-08-11 |
rat |
| P Mitchell, G Smythe, G Parker, K Wilhelm, I Hickie, H Brodaty, P Boyc. Hormonal responses to fenfluramine in depressive subtypes. The British journal of psychiatry : the journal of mental science. vol 157. 1991-12-06. PMID:2131137. |
in order to study putative differences in central neurotransmitter function in depressive subtypes, serum cortisol and prolactin responses to the putative serotonin agonist fenfluramine were examined in 30 subjects with major depression. |
1991-12-06 |
2023-08-11 |
human |