| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Silverston. New aspects in the treatment of depression. International clinical psychopharmacology. vol 6 Suppl 5. 1992-12-23. PMID:1431020. |
for resistant depression the addition of lithium (and/or tryptophan) may be effective, possibly through promoting 5-ht neurotransmission. |
1992-12-23 |
2023-08-11 |
Not clear |
| T Silverston. New aspects in the treatment of depression. International clinical psychopharmacology. vol 6 Suppl 5. 1992-12-23. PMID:1431020. |
continuous treatment with a selective 5-ht reuptake inhibitor can reduce the relapse rate in patients with recurrent depression. |
1992-12-23 |
2023-08-11 |
Not clear |
| H M Kravitz, R Katz, E Kot, N Helmke, J Fawcet. Biochemical clues to a fibromyalgia-depression link: imipramine binding in patients with fibromyalgia or depression and in healthy controls. The Journal of rheumatology. vol 19. issue 9. 1992-12-23. PMID:1433012. |
both fibromyalgia and depression may be related to disturbed serotonin metabolism, and an association between the 2 disorders has been postulated. |
1992-12-23 |
2023-08-11 |
human |
| S C Risch, C B Nemerof. Neurochemical alterations of serotonergic neuronal systems in depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1331029. |
the recent identification and cloning of multiple serotonergic receptor subtypes and the identification and cloning of the serotonin transporter offer further promise for elucidating the role of cns serotonergic neurons in the pathogenesis of depression and, moreover, for the development of innovative treatment strategies for this disorder. |
1992-12-11 |
2023-08-11 |
Not clear |
| V M Linnoila, M Virkkune. Aggression, suicidality, and serotonin. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1385390. |
studies from several countries, representing diverse cultures, have reported an association between violent suicide attempts by patients with unipolar depression and personality disorders and low concentrations of the major serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the cerebrospinal fluid (csf). |
1992-12-11 |
2023-08-11 |
Not clear |
| A F Schatzberg, A J Rothschil. Serotonin activity in psychotic (delusional) major depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1429484. |
serotonin activity in psychotic (delusional) major depression. |
1992-12-11 |
2023-08-11 |
Not clear |
| A F Schatzberg, A J Rothschil. Serotonin activity in psychotic (delusional) major depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1429484. |
the implications of these findings vis-à-vis a role for serotonin in delusional major depression are discussed. |
1992-12-11 |
2023-08-11 |
Not clear |
| A F Schatzberg, A J Rothschil. Serotonin activity in psychotic (delusional) major depression. The Journal of clinical psychiatry. vol 53 Suppl. 1992-12-11. PMID:1429484. |
future studies on serotonin as well as on 5-ht2 antagonists in delusional depression are warranted. |
1992-12-11 |
2023-08-11 |
Not clear |
| G M Asnis, S Wetzler, W C Sanderson, R S Kahn, H M van Praa. Functional interrelationship of serotonin and norepinephrine: cortisol response to MCPP and DMI in patients with panic disorder, patients with depression, and normal control subjects. Psychiatry research. vol 43. issue 1. 1992-12-09. PMID:1438618. |
this finding suggests that the functions (or dysfunctions) of the ne and 5ht systems may not be separate as is usually believed, and that the ne and 5ht disturbances observed in major depression and panic disorder may not be independent. |
1992-12-09 |
2023-08-11 |
human |
| J J Mann, P A McBride, G M Anderson, T A Mieczkowsk. Platelet and whole blood serotonin content in depressed inpatients: correlations with acute and life-time psychopathology. Biological psychiatry. vol 32. issue 3. 1992-12-08. PMID:1420642. |
platelet or whole blood serotonin content did not differ significantly in patients with major depression compared to healthy controls, but within the patient group, platelet serotonin levels correlated negatively with severity of depression (r = -0.49, p = 0.007). |
1992-12-08 |
2023-08-11 |
Not clear |
| J J Mann, P A McBride, G M Anderson, T A Mieczkowsk. Platelet and whole blood serotonin content in depressed inpatients: correlations with acute and life-time psychopathology. Biological psychiatry. vol 32. issue 3. 1992-12-08. PMID:1420642. |
this study provides evidence for an association between lower platelet serotonin content and depression and suicidal behavior, and association of higher platelet serotonin content and comorbid borderline personality disorder and behavior traits such as aggressivity. |
1992-12-08 |
2023-08-11 |
Not clear |
| C McAdams, F J Colohan, J Brophy, B E Leonar. Alteration by a plasma factor of platelet aggregation and 5HT uptake in depression. Biological psychiatry. vol 32. issue 3. 1992-12-08. PMID:1420645. |
alteration by a plasma factor of platelet aggregation and 5ht uptake in depression. |
1992-12-08 |
2023-08-11 |
Not clear |
| A C Power, P J Cowe. Neuroendocrine challenge tests: assessment of 5-HT function in anxiety and depression. Molecular aspects of medicine. vol 13. issue 3. 1992-12-04. PMID:1435104. |
neuroendocrine challenge tests: assessment of 5-ht function in anxiety and depression. |
1992-12-04 |
2023-08-11 |
Not clear |
| E McCance-Katz, L H Price, D S Charney, G R Heninge. Serotonergic function during lithium augmentation of refractory depression. Psychopharmacology. vol 108. issue 1-2. 1992-11-25. PMID:1410150. |
we used the l-trp test to assess the role of serotonin in the mechanism of action of lithium augmentation in refractory major depression. |
1992-11-25 |
2023-08-11 |
Not clear |
| G Curzon, G A Kennett, G S Sarna, P S Whitto. The effects of tianeptine and other antidepressants on a rat model of depression. The British journal of psychiatry. Supplement. issue 15. 1992-11-23. PMID:1356358. |
the model is associated with elevation in corticosterone, reflects the higher incidence of depression in women, and shows increased post-synaptic 5-ht function with adaptation. |
1992-11-23 |
2023-08-11 |
rat |
| D Morin, R Monteau, G Hilair. Compared effects of serotonin on cervical and hypoglossal inspiratory activities: an in vitro study in the newborn rat. The Journal of physiology. vol 451. 1992-11-23. PMID:1403827. |
experiments were performed on the brain stem-spinal cord preparation of newborn rats, in which the phrenic and hypoglossal nerves continue to show rhythmic respiratory activity in vitro, in order to compare the effects of serotonin (5-ht) on both activities and to analyse the mechanisms responsible for the depression by 5-ht of the hypoglossal activity. |
1992-11-23 |
2023-08-11 |
rat |
| D Morin, R Monteau, G Hilair. Compared effects of serotonin on cervical and hypoglossal inspiratory activities: an in vitro study in the newborn rat. The Journal of physiology. vol 451. 1992-11-23. PMID:1403827. |
the 5-ht depression of the hypoglossal discharge was prevented by applying a pretreatment with a specific 5-ht2 antagonist (ketanserin). |
1992-11-23 |
2023-08-11 |
rat |
| D Morin, R Monteau, G Hilair. Compared effects of serotonin on cervical and hypoglossal inspiratory activities: an in vitro study in the newborn rat. The Journal of physiology. vol 451. 1992-11-23. PMID:1403827. |
local application of 5-ht within the hypoglossal motor nucleus decreased the hypoglossal output, revealing that the 5-ht depression of the hypoglossal discharge was at least partly mediated by the 5-ht effects at the level of the motoneurons. |
1992-11-23 |
2023-08-11 |
rat |
| R Seth, A L Jennings, J Bindman, J Phillips, K Bergman. Combination treatment with noradrenalin and serotonin reuptake inhibitors in resistant depression. The British journal of psychiatry : the journal of mental science. vol 161. 1992-11-20. PMID:1327396. |
combination treatment with noradrenalin and serotonin reuptake inhibitors in resistant depression. |
1992-11-20 |
2023-08-11 |
Not clear |
| R Seth, A L Jennings, J Bindman, J Phillips, K Bergman. Combination treatment with noradrenalin and serotonin reuptake inhibitors in resistant depression. The British journal of psychiatry : the journal of mental science. vol 161. 1992-11-20. PMID:1327396. |
eight cases of resistant recurrent depression were treated with a combination of nortriptyline and a new serotonin reuptake inhibitor, with or without concurrent lithium therapy. |
1992-11-20 |
2023-08-11 |
Not clear |