| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Holohean, J C Hackman, S B Shope, R A Davidof. Activation of 5-HT1C/2 receptors depresses polysynaptic reflexes and excitatory amino acid-induced motoneuron responses in frog spinal cord. Brain research. vol 579. issue 1. 1992-08-10. PMID:1320445. |
the glycine receptor site associated with the nmda receptor did not appear to be affected by 5-ht because saturation of the site by excess glycine did not alter the 5-ht-induced depression of nmda responses. |
1992-08-10 |
2023-08-11 |
Not clear |
| A D Levy, L D Van de Ka. Endocrine and receptor pharmacology of serotonergic anxiolytics, antipsychotics and antidepressants. Life sciences. vol 51. issue 2. 1992-07-28. PMID:1352027. |
several classes of drugs that modify serotonin (5-ht) neurotransmission are either currently used, or are being evaluated for their potential use in the treatment of anxiety, schizophrenia, and depression. |
1992-07-28 |
2023-08-11 |
Not clear |
| M J Goldblatt, A F Schatzber. Does treatment with antidepressant medication increase suicidal behavior? International clinical psychopharmacology. vol 6. issue 4. 1992-07-01. PMID:1816279. |
in this paper we briefly outline previous studies on the role of serotonin in suicidal behavior in depression; and review the debate about antidepressants adversely affecting suicidal behavior. |
1992-07-01 |
2023-08-11 |
Not clear |
| D J Desmecht, A S Linden, F A Rollin, H Amory, P M Lekeu. Effect of intravenous and aerosol administration of 5-hydroxytryptamine on pulmonary function values in healthy calves. American journal of veterinary research. vol 53. issue 3. 1992-06-30. PMID:1595956. |
it was concluded that 5-ht induces reversible bronchoconstriction and pulmonary vasoconstriction in healthy unsedated calves, 5-ht-induced functional alterations depend on the speed of administration, and excess of 5-ht production or depression in uptake by the lungs during bovine respiratory tract diseases could contribute to pulmonary dysfunction. |
1992-06-30 |
2023-08-11 |
cattle |
| P J García Ruiz, M A Mena, N Peñafiel, J G De Yébene. Cinnarizine-induced parkinsonism in primates. Clinical neuropharmacology. vol 15. issue 2. 1992-06-29. PMID:1375537. |
our data suggest a predominant presynaptic effect on da and 5-ht neurons; and could account for the longstanding parkinsonism induced by calcium antagonist in some patients as well as the depression observed in these subjects. |
1992-06-29 |
2023-08-11 |
human |
| A F Schatzberg, A J Rothschil. Psychotic (delusional) major depression: should it be included as a distinct syndrome in DSM-IV? The American journal of psychiatry. vol 149. issue 6. 1992-06-25. PMID:1590491. |
studies have found significant differences between patients with psychotic and nonpsychotic depression in glucocorticoid activity, dopamine beta-hydroxylase activity, levels of dopamine and serotonin metabolites, sleep measures, and ventricle-to-brain ratios. |
1992-06-25 |
2023-08-11 |
Not clear |
| J D Amsterda. Gepirone, a selective serotonin (5HT1A) partial agonist in the treatment of major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 3. 1992-06-24. PMID:1350353. |
gepirone, a selective serotonin (5ht1a) partial agonist in the treatment of major depression. |
1992-06-24 |
2023-08-11 |
human |
| J D Amsterda. Gepirone, a selective serotonin (5HT1A) partial agonist in the treatment of major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 3. 1992-06-24. PMID:1350353. |
the present study assessed the potential antidepressant action of gepirone hydrochloride, an azapirone serotonin (5-ht1a) partial agonist in patients with major depression. |
1992-06-24 |
2023-08-11 |
human |
| M H Pietraszek, T Urano, K Sumiyoshi, Y Takada, A Takada, K Ohara, N Kondo, K Ohar. Diurnal variations of whole blood serotonin content in patients with depression and neurosis. Journal of neurology, neurosurgery, and psychiatry. vol 55. issue 4. 1992-06-18. PMID:1583529. |
diurnal variations of whole blood serotonin content in patients with depression and neurosis. |
1992-06-18 |
2023-08-11 |
Not clear |
| D S Millson, C L Jessup, A Swaisland, S Haworth, A Rushton, J D Harr. The effects of a selective 5-HT2 receptor antagonist (ICI 170,809) on platelet aggregation and pupillary responses in healthy volunteers. British journal of clinical pharmacology. vol 33. issue 3. 1992-06-10. PMID:1576048. |
the in vitro platelet 5-ht aggregation response was reduced by ici 170,809, with depression of the dose-response curve to 5-ht at all concentrations of 5-ht and with no evidence for a parallel shift. |
1992-06-10 |
2023-08-11 |
human |
| A J Stoess. Prevention and management of late stage complications in Parkinson's disease. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 19. issue 1 Suppl. 1992-06-02. PMID:1571855. |
depression in pd is associated with decreased levels of noradrenaline and 5-ht and responds to tricyclic antidepressants. |
1992-06-02 |
2023-08-11 |
Not clear |
| A Płaźnik, W Kostowsk. The involvement of serotonin and noradrenaline in the psychopathological processes of stress and depression: animal models and the effect of antidepressant drugs. Polish journal of pharmacology and pharmacy. vol 43. issue 4. 1992-06-02. PMID:1811222. |
the involvement of serotonin and noradrenaline in the psychopathological processes of stress and depression: animal models and the effect of antidepressant drugs. |
1992-06-02 |
2023-08-11 |
Not clear |
| W K Goodman, C J McDougle, L H Pric. Pharmacotherapy of obsessive compulsive disorder. The Journal of clinical psychiatry. vol 53 Suppl. 1992-05-21. PMID:1532962. |
the authors briefly review studies of the efficacy of potent serotonin reuptake inhibitors (sris) (e.g., clomipramine, fluvoxamine) in obsessive compulsive disorder (ocd) and compare the use of antidepressants in the treatment of depression and ocd. |
1992-05-21 |
2023-08-11 |
Not clear |
| S Venkataraman, M W Naylor, C A Kin. Mania associated with fluoxetine treatment in adolescents. Journal of the American Academy of Child and Adolescent Psychiatry. vol 31. issue 2. 1992-05-21. PMID:1564030. |
fluoxetine, a selective serotonin reuptake inhibitor, is gaining increased acceptance in the treatment of adolescent depression. |
1992-05-21 |
2023-08-11 |
Not clear |
| I M Anderson, C J Ware, J M da Roza Davis, P J Cowe. Decreased 5-HT-mediated prolactin release in major depression. The British journal of psychiatry : the journal of mental science. vol 160. 1992-05-20. PMID:1562864. |
the prolactin response to intravenous clomipramine, a 5-ht uptake inhibitor, was significantly attenuated in 12 patients with major depression. |
1992-05-20 |
2023-08-11 |
Not clear |
| A L Peyton, R Carpenter, K Rutkowsk. The stereospecific determination of fluoxetine and norfluoxetine enantiomers in human plasma by high-pressure liquid chromatography (HPLC) with fluorescence detection. Pharmaceutical research. vol 8. issue 12. 1992-05-19. PMID:1808619. |
f is a serotonin uptake inhibitor used in the treatment of depression and is administered as a racemate. |
1992-05-19 |
2023-08-11 |
human |
| S W Burto. A review of fluvoxamine and its uses in depression. International clinical psychopharmacology. vol 6 Suppl 3. 1992-05-11. PMID:1806631. |
fluvoxamine is a potent and specific 5-ht reuptake inhibitor which has been available since 1983 and is estimated to have been given to two and a half million patients since it was first investigated in patients with depression in the late 1970s. |
1992-05-11 |
2023-08-11 |
Not clear |
| J F Deaki. Depression and 5HT. International clinical psychopharmacology. vol 6 Suppl 3. 1992-05-11. PMID:1806632. |
depression and 5ht. |
1992-05-11 |
2023-08-11 |
Not clear |
| J F Deaki. Depression and 5HT. International clinical psychopharmacology. vol 6 Suppl 3. 1992-05-11. PMID:1806632. |
5ht has been implicated in mechanisms of anxiety and depression for many years but the evidence is contradictory. |
1992-05-11 |
2023-08-11 |
Not clear |
| S M Hourani, D A Hall, C J Niema. Effects of the P2-purinoceptor antagonist, suramin, on human platelet aggregation induced by adenosine 5'-diphosphate. British journal of pharmacology. vol 105. issue 2. 1992-05-08. PMID:1559134. |
suramin (200-400 microm) also noncompetitively inhibited aggregation induced by u46619 (a thromboxane receptor agonist) or by 5-hydroxytryptamine in the presence of adrenaline (100 microm), and caused a depression of the maximal response to these agonists. |
1992-05-08 |
2023-08-11 |
human |