| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E A Engleman, J M Murphy, F C Zhou, J N Hingtge. Response suppression induced with selective 5-HT agonists can be differentially blocked with LY53857 in an animal model of depression. Neurochemical research. vol 17. issue 5. 1992-10-22. PMID:1388251. |
response suppression induced with selective 5-ht agonists can be differentially blocked with ly53857 in an animal model of depression. |
1992-10-22 |
2023-08-11 |
rat |
| M L Rao, B Müller-Oerlinghausen, A Mackert, B Strebel, R D Stieglitz, H P Vol. Blood serotonin, serum melatonin and light therapy in healthy subjects and in patients with nonseasonal depression. Acta psychiatrica Scandinavica. vol 86. issue 2. 1992-10-20. PMID:1529735. |
blood serotonin, serum melatonin and light therapy in healthy subjects and in patients with nonseasonal depression. |
1992-10-20 |
2023-08-11 |
human |
| L Staner, C Kempenaers, M P Simonnet, L Fransolet, J Mendlewic. 5-HT2 receptor antagonism and slow-wave sleep in major depression. Acta psychiatrica Scandinavica. vol 86. issue 2. 1992-10-20. PMID:1529736. |
these results are in agreement with a potential 5-ht disturbance, particularly at the 5-ht2 receptor level, in some clinical forms of depression. |
1992-10-20 |
2023-08-11 |
human |
| M Zetin, M A Krame. Obsessive-compulsive disorder. Hospital & community psychiatry. vol 43. issue 7. 1992-10-02. PMID:1516899. |
serotonin reuptake inhibitors used in the treatment of depression have been found effective; clomipramine has produced the best results in large-scale tests. |
1992-10-02 |
2023-08-11 |
Not clear |
| O Spigse. [New therapeutic possibilities with drugs affecting serotonin receptors]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 112. issue 13. 1992-09-23. PMID:1509427. |
serotonin reuptake blockers have been found effective in the alleviation of depression and attacks of panic, and are at varying stages of clinical evaluation in the treatment of obsessive compulsive disorder, chronic pain, and bulimia nervosa. |
1992-09-23 |
2023-08-11 |
Not clear |
| T D Brewerto. Serotonin function in depression: effects of seasonality? The American journal of psychiatry. vol 149. issue 9. 1992-09-15. PMID:1482444. |
serotonin function in depression: effects of seasonality? |
1992-09-15 |
2023-08-11 |
Not clear |
| C B Nemerof. The presynaptic serotonin uptake site in depression. Clinical neuropharmacology. vol 15 Suppl 1 Pt A. 1992-09-14. PMID:1498865. |
the presynaptic serotonin uptake site in depression. |
1992-09-14 |
2023-08-11 |
Not clear |
| J F Greden, A C Pand. Treatment of resistant depression with 5-HT uptake inhibitors. Clinical neuropharmacology. vol 15 Suppl 1 Pt A. 1992-09-14. PMID:1498908. |
treatment of resistant depression with 5-ht uptake inhibitors. |
1992-09-14 |
2023-08-11 |
Not clear |
| S M Stah. Neuroendocrine markers of serotonin responsivity in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 5. 1992-09-10. PMID:1496123. |
neuroendocrine markers of serotonin responsivity in depression. |
1992-09-10 |
2023-08-11 |
human |
| M Kaneko, H Mashiko, T Yagiuchi, N Ohsuka, H Kumashir. 5HT2 receptor-mediated function in depressed patients: investigation by measuring 5HT-induced shape change of blood platelets. The Japanese journal of psychiatry and neurology. vol 46. issue 1. 1992-08-27. PMID:1635306. |
in patients after treatment (n = 12), in whom depression had been improved but drug therapy was continued, 5ht-sc in a concentration of 10(-5) m 5ht was observed more potently than that in healthy controls or untreated patients (p less than 0.05 and p less than 0.05, respectively). |
1992-08-27 |
2023-08-11 |
Not clear |
| S E Mølle. 5-HT uptake inhibitors and tricyclic antidepressants: relation between tryptophan availability and clinical response in depressed patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 1. issue 1. 1992-08-25. PMID:2136212. |
the amount of tryptophan (trp) available for transport from plasma into the brain was estimated in patients with major depression before treatment for 4 weeks with a 5-ht potentiating tricyclic antidepressant (tca), amitriptyline (n = 21) or clomipramine (n = 17), or a selective 5-ht uptake inhibitor, citalopram (n = 14) or paroxetine (n = 27). |
1992-08-25 |
2023-08-11 |
Not clear |
| T D Brewerton, D L Murphy, M D Lesem, H A Brandt, D C Jimerso. Headache responses following m-chlorophenylpiperazine in bulimics and controls. Headache. vol 32. issue 5. 1992-08-19. PMID:1628957. |
additional disturbances in 5-ht function, perhaps presynaptic ones, may be associated with anorexia nervosa and major depression. |
1992-08-19 |
2023-08-11 |
Not clear |
| T D Brewerton, D L Murphy, M D Lesem, H A Brandt, D C Jimerso. Headache responses following m-chlorophenylpiperazine in bulimics and controls. Headache. vol 32. issue 5. 1992-08-19. PMID:1628957. |
further studies exploring the functional integrity of 5-ht receptors and their subtypes are warranted in bulimic patients, as well as in patients with nonbulimic anorexia nervosa, minor and major depression without an eating disorder, and migraine and other headache patients. |
1992-08-19 |
2023-08-11 |
Not clear |
| A M Holohean, J C Hackman, S B Shope, R A Davidof. Activation of 5-HT1C/2 receptors depresses polysynaptic reflexes and excitatory amino acid-induced motoneuron responses in frog spinal cord. Brain research. vol 579. issue 1. 1992-08-10. PMID:1320445. |
the glycine receptor site associated with the nmda receptor did not appear to be affected by 5-ht because saturation of the site by excess glycine did not alter the 5-ht-induced depression of nmda responses. |
1992-08-10 |
2023-08-11 |
Not clear |
| A D Levy, L D Van de Ka. Endocrine and receptor pharmacology of serotonergic anxiolytics, antipsychotics and antidepressants. Life sciences. vol 51. issue 2. 1992-07-28. PMID:1352027. |
several classes of drugs that modify serotonin (5-ht) neurotransmission are either currently used, or are being evaluated for their potential use in the treatment of anxiety, schizophrenia, and depression. |
1992-07-28 |
2023-08-11 |
Not clear |
| M J Goldblatt, A F Schatzber. Does treatment with antidepressant medication increase suicidal behavior? International clinical psychopharmacology. vol 6. issue 4. 1992-07-01. PMID:1816279. |
in this paper we briefly outline previous studies on the role of serotonin in suicidal behavior in depression; and review the debate about antidepressants adversely affecting suicidal behavior. |
1992-07-01 |
2023-08-11 |
Not clear |
| D J Desmecht, A S Linden, F A Rollin, H Amory, P M Lekeu. Effect of intravenous and aerosol administration of 5-hydroxytryptamine on pulmonary function values in healthy calves. American journal of veterinary research. vol 53. issue 3. 1992-06-30. PMID:1595956. |
it was concluded that 5-ht induces reversible bronchoconstriction and pulmonary vasoconstriction in healthy unsedated calves, 5-ht-induced functional alterations depend on the speed of administration, and excess of 5-ht production or depression in uptake by the lungs during bovine respiratory tract diseases could contribute to pulmonary dysfunction. |
1992-06-30 |
2023-08-11 |
cattle |
| P J García Ruiz, M A Mena, N Peñafiel, J G De Yébene. Cinnarizine-induced parkinsonism in primates. Clinical neuropharmacology. vol 15. issue 2. 1992-06-29. PMID:1375537. |
our data suggest a predominant presynaptic effect on da and 5-ht neurons; and could account for the longstanding parkinsonism induced by calcium antagonist in some patients as well as the depression observed in these subjects. |
1992-06-29 |
2023-08-11 |
human |
| A F Schatzberg, A J Rothschil. Psychotic (delusional) major depression: should it be included as a distinct syndrome in DSM-IV? The American journal of psychiatry. vol 149. issue 6. 1992-06-25. PMID:1590491. |
studies have found significant differences between patients with psychotic and nonpsychotic depression in glucocorticoid activity, dopamine beta-hydroxylase activity, levels of dopamine and serotonin metabolites, sleep measures, and ventricle-to-brain ratios. |
1992-06-25 |
2023-08-11 |
Not clear |
| J D Amsterda. Gepirone, a selective serotonin (5HT1A) partial agonist in the treatment of major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 3. 1992-06-24. PMID:1350353. |
gepirone, a selective serotonin (5ht1a) partial agonist in the treatment of major depression. |
1992-06-24 |
2023-08-11 |
human |