| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L H Price, D S Charney, P L Delgado, G R Heninge. Serotonin function and depression: neuroendocrine and mood responses to intravenous L-tryptophan in depressed patients and healthy comparison subjects. The American journal of psychiatry. vol 148. issue 11. 1991-11-20. PMID:1928466. |
serotonin function and depression: neuroendocrine and mood responses to intravenous l-tryptophan in depressed patients and healthy comparison subjects. |
1991-11-20 |
2023-08-11 |
human |
| B A Goldsmith, T W Abram. Reversal of synaptic depression by serotonin at Aplysia sensory neuron synapses involves activation of adenylyl cyclase. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 20. 1991-11-15. PMID:1924365. |
reversal of synaptic depression by serotonin at aplysia sensory neuron synapses involves activation of adenylyl cyclase. |
1991-11-15 |
2023-08-11 |
aplysia |
| P M Ellis, G W Mellsop, R Beeston, R R Cook. Platelet tritiated imipramine binding in patients suffering from mania. Journal of affective disorders. vol 22. issue 3. 1991-11-05. PMID:1655851. |
this raises the possibility that changes in imipramine binding in depression and mania may be similar, consistent with the permissive hypothesis of serotonin function. |
1991-11-05 |
2023-08-11 |
human |
| A Płaźnik, R Stefański, W Pałejko, W Kostowsk. Serotonergic mechanisms in the nucleus accumbens affected by chronic desipramine treatment. Pharmacology, biochemistry, and behavior. vol 39. issue 1. 1991-11-01. PMID:1833782. |
chronic, but not acute treatment of rats with desipramine (10 mg/kg, po, twice a day for 21 days, tests were performed 24 h after the last dose) significantly attenuated behavioral depression after 5-ht and quipazine microinjections, while the effect of buspirone was left unchanged. |
1991-11-01 |
2023-08-11 |
rat |
| M Sano, M Stanley, A Lawton, L Coté, J Williams, Y Stern, K Marder, R Mayeu. Tritiated imipramine binding. A peripheral marker for serotonin in Parkinson's disease. Archives of neurology. vol 48. issue 10. 1991-10-29. PMID:1718247. |
tritiated imipramine binding in platelets has been used to evaluate serotonin activity in depression in previous studies. |
1991-10-29 |
2023-08-11 |
Not clear |
| M Sano, M Stanley, A Lawton, L Coté, J Williams, Y Stern, K Marder, R Mayeu. Tritiated imipramine binding. A peripheral marker for serotonin in Parkinson's disease. Archives of neurology. vol 48. issue 10. 1991-10-29. PMID:1718247. |
we also found a significant correlation between the receptor site values in platelets and cerebrospinal fluid levels of the serotonin metabolite, 5-hydroxyindoleacetic acid (r = .59), but this was independent of a diagnosis of depression. |
1991-10-29 |
2023-08-11 |
Not clear |
| M Sano, M Stanley, A Lawton, L Coté, J Williams, Y Stern, K Marder, R Mayeu. Tritiated imipramine binding. A peripheral marker for serotonin in Parkinson's disease. Archives of neurology. vol 48. issue 10. 1991-10-29. PMID:1718247. |
our results strongly support a generalized alteration in serotonin metabolism in depressed patients with pd, but tritiated imipramine binding in platelets is not a useful diagnostic tool for depression. |
1991-10-29 |
2023-08-11 |
Not clear |
| W Pöldinger, B Calanchini, W Schwar. A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan and fluvoxamine. Psychopathology. vol 24. issue 2. 1991-10-07. PMID:1909444. |
a functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan and fluvoxamine. |
1991-10-07 |
2023-08-11 |
Not clear |
| M H Pietraszek, T Urano, K Sumioshi, K Serizawa, S Takahashi, Y Takada, A Takad. Alcohol-induced depression: involvement of serotonin. Alcohol and alcoholism (Oxford, Oxfordshire). vol 26. issue 2. 1991-10-03. PMID:1878077. |
alcohol-induced depression: involvement of serotonin. |
1991-10-03 |
2023-08-11 |
human |
| M H Pietraszek, T Urano, K Sumioshi, K Serizawa, S Takahashi, Y Takada, A Takad. Alcohol-induced depression: involvement of serotonin. Alcohol and alcoholism (Oxford, Oxfordshire). vol 26. issue 2. 1991-10-03. PMID:1878077. |
the diurnal rhythm of 5-ht in subjects who the day before had drunk alcohol was quite different from the control group, but very similar to that of patients with depression. |
1991-10-03 |
2023-08-11 |
human |
| M H Pietraszek, T Urano, K Sumioshi, K Serizawa, S Takahashi, Y Takada, A Takad. Alcohol-induced depression: involvement of serotonin. Alcohol and alcoholism (Oxford, Oxfordshire). vol 26. issue 2. 1991-10-03. PMID:1878077. |
the results strongly suggest that the mechanism of depression after alcohol drinking may be related to serotonin. |
1991-10-03 |
2023-08-11 |
human |
| D Healy, J Calvin, A M Whitehouse, W White, H Wilton-Cox, A E Theodorou, K M Lawrence, R W Horton, E S Payke. Alpha-1-acid glycoprotein in major depressive and eating disorders. Journal of affective disorders. vol 22. issue 1-2. 1991-10-01. PMID:1652602. |
further studies are suggested to explore the issue of whether variations in agp level are responsible for the abnormalities in platelet 5ht uptake and tritiated imipramine binding that have been reported in depression or for treatment non-response. |
1991-10-01 |
2023-08-11 |
human |
| H Agren, L Reibring, P Hartvig, J Tedroff, P Bjurling, K Hörnfeldt, Y Andersson, H Lundqvist, B Långströ. Low brain uptake of L-[11C]5-hydroxytryptophan in major depression: a positron emission tomography study on patients and healthy volunteers. Acta psychiatrica Scandinavica. vol 83. issue 6. 1991-10-01. PMID:1882697. |
the findings emphasize that serotonin is involved in depressive pathophysiology and support earlier suggestions that the transport of 5-htp across the blood-brain barrier is compromised in major depression. |
1991-10-01 |
2023-08-11 |
human |
| S E Molchan, B A Lawlor, J L Hill, R A Martinez, C L Davis, A M Mellow, D R Rubinow, T Sunderlan. CSF monoamine metabolites and somatostatin in Alzheimer's disease and major depression. Biological psychiatry. vol 29. issue 11. 1991-09-26. PMID:1714776. |
further exploration of the relationship between the somatostatin and serotonin systems may provide clues as to how neuropeptides interact with monoamine neurotransmitters and what role they have in depression. |
1991-09-26 |
2023-08-11 |
Not clear |
| D Heal. The marketing of 5-hydroxytryptamine: depression or anxiety? The British journal of psychiatry : the journal of mental science. vol 158. 1991-09-26. PMID:1873625. |
the marketing of 5-hydroxytryptamine: depression or anxiety? |
1991-09-26 |
2023-08-11 |
Not clear |
| L Staner, J Mendlewic. [Biological psychiatry and current classifications of depressive disorders]. L'Encephale. vol 17. issue 3. 1991-09-11. PMID:1864251. |
for example, catecholamines and serotonin metabolism seem to reflect respectively psychomotor status and aggressiveness in depression. |
1991-09-11 |
2023-08-11 |
Not clear |
| V O'Keane, T G Dina. Prolactin and cortisol responses to d-fenfluramine in major depression: evidence for diminished responsivity of central serotonergic function. The American journal of psychiatry. vol 148. issue 8. 1991-08-20. PMID:1853948. |
the authors' goal, therefore, was to look at 5-ht function in depression using the d isomer of fenfluramine as a probe. |
1991-08-20 |
2023-08-11 |
Not clear |
| D H Bobker, J T William. Cocaine and amphetamine interact at 5-HT synapses through distinct mechanisms in guinea-pig prepositus hypoglossi. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 7. 1991-08-12. PMID:2066779. |
the depression of the ipsp is most likely due to a presynaptic effect, because cocaine augmented the response to applied 5-ht. |
1991-08-12 |
2023-08-11 |
Not clear |
| J L Rausch, F G Moelle. Kinetic effects of desmethylimipramine treatment on platelet serotonin uptake in depressed patients: a comparison with imipramine. Psychiatry research. vol 36. issue 3. 1991-08-08. PMID:2062971. |
although dmi is considered a preferential norepinephrine uptake inhibitor, the results suggest the following: (1) significant decreases in the apparent platelet 5ht affinity are achieved with dmi; (2) the inhibition kinetics in depressed patients are competitive; (3) there was a significant relationship between km change and depression outcome with dmi discontinuation; and (4) dmi, as a metabolite, appears to contribute to the 5ht uptake inhibition of imi in vivo. |
1991-08-08 |
2023-08-11 |
Not clear |
| J T Buchanan, S Grillne. 5-Hydroxytryptamine depresses reticulospinal excitatory postsynaptic potentials in motoneurons of the lamprey. Neuroscience letters. vol 122. issue 1. 1991-08-01. PMID:1676146. |
the depression could be produced either by local application of small volumes of 10 mm 5-ht to the surface of the spinal cord or by bath-application of 1 or 10 microm 5-ht. |
1991-08-01 |
2023-08-11 |
Not clear |