| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Plein, M Ber. Changes in the platelet intracellular calcium response to serotonin in patients with major depression treated with electroconvulsive therapy: state or trait marker status. International clinical psychopharmacology. vol 15. issue 2. 2000-06-16. PMID:10759340. |
platelet serotonin type 2a receptor (5-ht2a) sensitivity changes have previously been documented in depression, although it is unclear if this represents a stable trait marker of the illness, or whether it represents an acute state marker of depression that would change with treatment. |
2000-06-16 |
2023-08-12 |
Not clear |
| H Plein, M Ber. Changes in the platelet intracellular calcium response to serotonin in patients with major depression treated with electroconvulsive therapy: state or trait marker status. International clinical psychopharmacology. vol 15. issue 2. 2000-06-16. PMID:10759340. |
using spectrofluorometry, the platelet 5ht2a, receptor sensitivity as reflected by the intracellular calcium response to serotonin stimulation, was measured every week in patients suffering from major depression and undergoing ect. |
2000-06-16 |
2023-08-12 |
Not clear |
| H Plein, M Ber. Changes in the platelet intracellular calcium response to serotonin in patients with major depression treated with electroconvulsive therapy: state or trait marker status. International clinical psychopharmacology. vol 15. issue 2. 2000-06-16. PMID:10759340. |
there was a significant drop in the platelet response to serotonin stimulation over a course of ect, with an associated progressive decrease in hamilton rating scale of depression (ham-d) scores. |
2000-06-16 |
2023-08-12 |
Not clear |
| E M Sullivan, R I Griffiths, R G Frank, M J Strauss, R J Herbert, J Clouse, H H Goldma. One-year costs of second-line therapies for depression. The Journal of clinical psychiatry. vol 61. issue 4. 2000-06-02. PMID:10830151. |
we compared patterns of medical resource utilization and costs among patients receiving a serotonin-norepinephrine reuptake inhibitor (venlafaxine), one of the selective serotonin reuptake inhibitors (ssris), one of the tricyclic agents (tcas), or 1 of 3 other second-line therapies for depression. |
2000-06-02 |
2023-08-12 |
Not clear |
| K L Weihs, E C Settle, S R Batey, T L Houser, R M Donahue, J A Asche. Bupropion sustained release versus paroxetine for the treatment of depression in the elderly. The Journal of clinical psychiatry. vol 61. issue 3. 2000-05-25. PMID:10817105. |
this study compared the efficacy and safety of bupropion sustained release (sr) with the selective serotonin reuptake inhibitor paroxetine in the treatment of major depression in elderly outpatients. |
2000-05-25 |
2023-08-12 |
Not clear |
| K A Smith, C Williams, P J Cowe. Impaired regulation of brain serotonin function during dieting in women recovered from depression. The British journal of psychiatry : the journal of mental science. vol 176. 2000-05-19. PMID:10789331. |
impaired regulation of brain serotonin function during dieting in women recovered from depression. |
2000-05-19 |
2023-08-12 |
Not clear |
| K A Smith, C Williams, P J Cowe. Impaired regulation of brain serotonin function during dieting in women recovered from depression. The British journal of psychiatry : the journal of mental science. vol 176. 2000-05-19. PMID:10789331. |
amino acid mixtures that lower brain availability of the serotonin (5-ht) precursor tryptophan produce acute depressive relapse in women with a history of major depression. |
2000-05-19 |
2023-08-12 |
Not clear |
| S Misri, D Kostaras, X Kostara. The use of selective serotonin reuptake inhibitors during pregnancy and lactation: current knowledge. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 45. issue 3. 2000-05-17. PMID:10779887. |
this article reviews the effects of the selective serotonin reuptake inhibitor (ssri) class of antidepressants in pregnant and lactating women for the treatment of depression and anxiety disorders. |
2000-05-17 |
2023-08-12 |
human |
| S D Mendelso. The current status of the platelet 5-HT(2A) receptor in depression. Journal of affective disorders. vol 57. issue 1-3. 2000-05-16. PMID:10708812. |
the current status of the platelet 5-ht(2a) receptor in depression. |
2000-05-16 |
2023-08-12 |
human |
| S D Mendelso. The current status of the platelet 5-HT(2A) receptor in depression. Journal of affective disorders. vol 57. issue 1-3. 2000-05-16. PMID:10708812. |
the author reviews the current status of the platelet serotonin (5-ht)(2a) receptor in depression. |
2000-05-16 |
2023-08-12 |
human |
| S D Mendelso. The current status of the platelet 5-HT(2A) receptor in depression. Journal of affective disorders. vol 57. issue 1-3. 2000-05-16. PMID:10708812. |
5-ht(2a) receptor density tends to increase in depression, although this more clearly relates to suicidality than depression per se. |
2000-05-16 |
2023-08-12 |
human |
| S D Mendelso. The current status of the platelet 5-HT(2A) receptor in depression. Journal of affective disorders. vol 57. issue 1-3. 2000-05-16. PMID:10708812. |
nonetheless, there is little evidence that the degree of departure from normal density or activity of platelet of 5-ht(2a) receptors reflects severity of depression. |
2000-05-16 |
2023-08-12 |
human |
| W Liu, N Gu, G Feng, S Li, S Bai, J Zhang, T Shen, H Xue, G Breen, D St Clair, L H. Tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in Han Chinese. Pharmacogenetics. vol 9. issue 4. 2000-05-12. PMID:10780268. |
tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in han chinese. |
2000-05-12 |
2023-08-12 |
Not clear |
| A A Badaw. Tryptophan metabolism in alcoholism. Advances in experimental medicine and biology. vol 467. 2000-05-09. PMID:10721064. |
acutely, ethanol depletes brain serotonin in normal subjects, which may explain alcohol-induced aggression in susceptible individuals and also the incidence of depression in alcoholism. |
2000-05-09 |
2023-08-12 |
mouse |
| M Faga. [Withdrawal syndrome after the use of serotonin reuptake inhibitors]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 120. issue 8. 2000-05-09. PMID:10795494. |
the use of serotonin reuptake inhibitors in the treatment of depression has increased significantly over the years since their introduction in norway in the early 1990s. |
2000-05-09 |
2023-08-12 |
Not clear |
| M Hansenne, M Anssea. P300 event-related potential and serotonin-1A activity in depression. European psychiatry : the journal of the Association of European Psychiatrists. vol 14. issue 3. 2000-05-02. PMID:10572339. |
since serotonin disturbances seem to play a critical role in depression, the aim of the study was to assess the possible relationships between the p300 event-related brain potential and serotonergic activity in depression. |
2000-05-02 |
2023-08-12 |
Not clear |
| N Haddjeri, S T Szabo, C de Montigny, P Blie. Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 4. 2000-05-01. PMID:10700654. |
the present results support the notion that the addition of lithium to antidepressants may produce a therapeutic response in treatment-resistant depression by enhancing 5-ht neurotransmission. |
2000-05-01 |
2023-08-12 |
rat |
| G Erdemli, V Crunell. Release of monoamines and nitric oxide is involved in the modulation of hyperpolarization-activated inward current during acute thalamic hypoxia. Neuroscience. vol 96. issue 3. 2000-04-27. PMID:10717436. |
separate application of noradrenaline, serotonin, histamine and nitric oxide antagonists produced only a small depression of the hypoxic response, while concomitant bath application of these antagonists decreased the hypoxia-induced changes in g(n) and i(bh) by 55 and 42%, respectively (n = 12). |
2000-04-27 |
2023-08-12 |
Not clear |
| P L Delgad. Depression: the case for a monoamine deficiency. The Journal of clinical psychiatry. vol 61 Suppl 6. 2000-04-26. PMID:10775018. |
the monoamine hypothesis of depression predicts that the underlying pathophysiologic basis of depression is a depletion in the levels of serotonin, norepinephrine, and/or dopamine in the central nervous system. |
2000-04-26 |
2023-08-12 |
human |
| B E Leonar. Evidence for a biochemical lesion in depression. The Journal of clinical psychiatry. vol 61 Suppl 6. 2000-04-26. PMID:10775019. |
for example, there is evidence for a reduction in the activity of the serotonin reuptake transporter in patients with depression and an increase in the density of 5-ht2 receptors in the brains of suicide victims. |
2000-04-26 |
2023-08-12 |
Not clear |