| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Margus Tõnissaar, Tanel Mällo, Marika Eller, Riina Häidkind, Kadri Kõiv, Jaanus Harr. Rat behavior after chronic variable stress and partial lesioning of 5-HT-ergic neurotransmission: effects of citalopram. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17826880. |
deficits in serotonergic (5-ht-ergic) neurotransmission and stressful life events have been implicated in affective disorders, and chronic variable stress (cvs) can elicit behavioral changes reminiscent of increased emotionality, anxiety and atypical depression after partial 5-ht depletion. |
2008-05-02 |
2023-08-12 |
rat |
| Margus Tõnissaar, Tanel Mällo, Marika Eller, Riina Häidkind, Kadri Kõiv, Jaanus Harr. Rat behavior after chronic variable stress and partial lesioning of 5-HT-ergic neurotransmission: effects of citalopram. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17826880. |
in conclusion, citalopram treatment prevented several effects of either 5-ht depletion or combined pca+cvs treatment, suggesting that these behavioral changes could be used in studies on the neural mechanisms underlying emotional behavior that may have relevance to the neurobiology of depression. |
2008-05-02 |
2023-08-12 |
rat |
| Katharina Domschke, Christa Hohoff, Lena S Mortensen, Tilmann Roehrs, Jürgen Deckert, Volker Arolt, Bernhard T Baun. Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17884271. |
the present results suggest that high-activity mao-a genotypes possibly by consecutively decreased serotonin and/or norepinephrine availability negatively influence antidepressant treatment response during the first six weeks of pharmacological treatment in female patients with major depression. |
2008-05-02 |
2023-08-12 |
Not clear |
| Valeria Carola, Giovanni Frazzetto, Tiziana Pascucci, Enrica Audero, Stefano Puglisi-Allegra, Simona Cabib, Klaus-Peter Lesch, Cornelius Gros. Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression. Biological psychiatry. vol 63. issue 9. 2008-04-29. PMID:17949690. |
identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression. |
2008-04-29 |
2023-08-12 |
mouse |
| Valeria Carola, Giovanni Frazzetto, Tiziana Pascucci, Enrica Audero, Stefano Puglisi-Allegra, Simona Cabib, Klaus-Peter Lesch, Cornelius Gros. Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression. Biological psychiatry. vol 63. issue 9. 2008-04-29. PMID:17949690. |
a polymorphism in the serotonin transporter (5-htt) gene modulates the association between adverse early experiences and risk for major depression in adulthood. |
2008-04-29 |
2023-08-12 |
mouse |
| Ian H Gotlib, Jutta Joormann, Kelly L Minor, Joachim Hallmaye. HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression. Biological psychiatry. vol 63. issue 9. 2008-04-29. PMID:18005940. |
recent evidence indicates that individuals who are homozygous for the short (s) allele in the promoter region of the serotonin transporter gene have higher rates of depression and other psychiatric disorders as a function of exposure to increasing levels of stressful life events than do individuals who have one or two copies of the long (l) allele. |
2008-04-29 |
2023-08-12 |
Not clear |
| Edward G Meloni, Catherine L Reedy, Bruce M Cohen, William A Carlezo. Activation of raphe efferents to the medial prefrontal cortex by corticotropin-releasing factor: correlation with anxiety-like behavior. Biological psychiatry. vol 63. issue 9. 2008-04-29. PMID:18061145. |
parallel lines of research suggest that dysfunction affecting both corticotropin-releasing factor (crf) and serotonin (5-ht) systems is involved in the pathophysiology of psychiatric illnesses such as anxiety and depression. |
2008-04-29 |
2023-08-12 |
Not clear |
| Gabi Koller, Peter Zill, Thomas Skoruppa, Brigitta Bondy, Ulrich W Preuss, Michael Soyk. Low level of harm avoidance is associated with serotonin transporter functional haplotype in alcohol-dependent individuals. Psychiatric genetics. vol 18. issue 2. 2008-04-28. PMID:18349696. |
higher serotonin levels among carriers of the s allele might exhibit increased liability of serotonin-mediated, psychopathology-like anxiety and depression and may impair social skills reflected by harm avoidance. |
2008-04-28 |
2023-08-12 |
Not clear |
| Thomas J Stamm, Mazda Adli, Julia Kirchheiner, Michael N Smolka, Rolf Kaiser, Pierre Benoit Tremblay, Michael Baue. Serotonin transporter gene and response to lithium augmentation in depression. Psychiatric genetics. vol 18. issue 2. 2008-04-28. PMID:18349701. |
serotonin transporter gene and response to lithium augmentation in depression. |
2008-04-28 |
2023-08-12 |
Not clear |
| Michael Alan Horberg, Michael Jonah Silverberg, Leo Bartemeier Hurley, William James Towner, Daniel Benjamin Klein, Susan Bersoff-Matcha, Winkler Gabriel Weinberg, Diana Antoniskis, Miguel Mogyoros, Wayne Thomas Dodge, Robert Dobrinich, Charles Price Quesenberry, Drew Anthony Kovac. Effects of depression and selective serotonin reuptake inhibitor use on adherence to highly active antiretroviral therapy and on clinical outcomes in HIV-infected patients. Journal of acquired immune deficiency syndromes (1999). vol 47. issue 3. 2008-04-24. PMID:18091609. |
effects of depression and selective serotonin reuptake inhibitor use on adherence to highly active antiretroviral therapy and on clinical outcomes in hiv-infected patients. |
2008-04-24 |
2023-08-12 |
Not clear |
| Michael Alan Horberg, Michael Jonah Silverberg, Leo Bartemeier Hurley, William James Towner, Daniel Benjamin Klein, Susan Bersoff-Matcha, Winkler Gabriel Weinberg, Diana Antoniskis, Miguel Mogyoros, Wayne Thomas Dodge, Robert Dobrinich, Charles Price Quesenberry, Drew Anthony Kovac. Effects of depression and selective serotonin reuptake inhibitor use on adherence to highly active antiretroviral therapy and on clinical outcomes in HIV-infected patients. Journal of acquired immune deficiency syndromes (1999). vol 47. issue 3. 2008-04-24. PMID:18091609. |
to determine the impact of depression on highly active antiretroviral therapy (haart) adherence and clinical measures and investigate if selective serotonin reuptake inhibitors (ssris) improve these measures. |
2008-04-24 |
2023-08-12 |
Not clear |
| S Byford, B Barrett, C Roberts, P Wilkinson, B Dubicka, R G Kelvin, L White, C Ford, S Breen, I Goodye. Cost-effectiveness of selective serotonin reuptake inhibitors and routine specialist care with and without cognitive behavioural therapy in adolescents with major depression. The British journal of psychiatry : the journal of mental science. vol 191. 2008-04-23. PMID:18055956. |
cost-effectiveness of selective serotonin reuptake inhibitors and routine specialist care with and without cognitive behavioural therapy in adolescents with major depression. |
2008-04-23 |
2023-08-12 |
Not clear |
| Małgorzata M Potyralska, Andrzej K Krawczy. [Depression in patients with type 2 diabetes mellitus--clinical and therapeutical implications]. Wiadomosci lekarskie (Warsaw, Poland : 1960). vol 60. issue 9-10. 2008-04-22. PMID:18350720. |
selective serotonin reuptake inhibitors (ssri) are the drugs of choice in the pharmacological treatment of depression. |
2008-04-22 |
2023-08-12 |
Not clear |
| Balagopal Lakshmi, Mei-Ping Kung, Brian Lieberman, Jun Zhao, Rikki Waterhouse, Hank F Kun. (R)-N-Methyl-3-(3-(125)I-pyridin-2-yloxy)-3-phenylpropan-1-amine: a novel probe for norepinephrine transporters. Nuclear medicine and biology. vol 35. issue 1. 2008-04-21. PMID:18158942. |
alterations in serotonin and norepinephrine neuronal functions have been observed in patients with major depression. |
2008-04-21 |
2023-08-12 |
human |
| R Uher, P McGuffi. The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Molecular psychiatry. vol 13. issue 2. 2008-04-11. PMID:17700575. |
gene-environmental interaction (g x e) between a common functional polymorphism in the promoter region of the serotonin transporter gene (5-htt) and environmental adversity on the onset of depression in humans has been found in fifteen independent studies. |
2008-04-11 |
2023-08-12 |
Not clear |
| Craig H Mallinckrodt, Apurva Prakash, John P Houston, Ralph Swindle, Michael J Detke, Maurizio Fav. Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram). Neuropsychobiology. vol 56. issue 2-3. 2008-04-09. PMID:18037817. |
to test the hypothesis that in patients with major depressive disorder (mdd), the response for specific hamilton depression rating scale items will differ for duloxetine compared with selective serotonin reuptake inhibitors (ssris) and that patterns of response will differ based on symptom severity at baseline. |
2008-04-09 |
2023-08-12 |
Not clear |
| Pei-Xian Mao, Yi-Lang Tang, Feng Jiang, Liang Shu, Xiuling Gu, Ming Li, Mincai Qian, Cui Ma, Philip B Mitchell, Zhuo-Ji Ca. Escitalopram in major depressive disorder: a multicenter, randomized, double-blind, fixed-dose, parallel trial in a Chinese population. Depression and anxiety. vol 25. issue 1. 2008-04-03. PMID:17149753. |
escitalopram, the s-enantiomer of citalopram and the most selective of the selective serotonin reuptake inhibitor (ssri) has been shown to be efficacious in the treatment of major depression in white populations. |
2008-04-03 |
2023-08-12 |
Not clear |
| Sefi Kronenberg, Alan Apter, David Brent, Shella Schirman, Nadine Melhem, Nimrod Pick, Doron Gothelf, Miri Carmel, Amos Frisch, Abraham Weizma. Serotonin transporter polymorphism (5-HTTLPR) and citalopram effectiveness and side effects in children with depression and/or anxiety disorders. Journal of child and adolescent psychopharmacology. vol 17. issue 6. 2008-04-03. PMID:18315446. |
serotonin transporter polymorphism (5-httlpr) and citalopram effectiveness and side effects in children with depression and/or anxiety disorders. |
2008-04-03 |
2023-08-12 |
Not clear |
| Eydie L Moses-Kolko, Katherine L Wisner, Julie C Price, Sarah L Berga, Wayne C Drevets, Barbara H Hanusa, Tammy L Loucks, Carolyn C Meltze. Serotonin 1A receptor reductions in postpartum depression: a positron emission tomography study. Fertility and sterility. vol 89. issue 3. 2008-03-27. PMID:17543959. |
serotonin 1a receptor reductions in postpartum depression: a positron emission tomography study. |
2008-03-27 |
2023-08-12 |
Not clear |
| Stephen J Ferrando, Zachary Freyber. Treatment of depression in HIV positive individuals: a critical review. International review of psychiatry (Abingdon, England). vol 20. issue 1. 2008-03-26. PMID:18240063. |
there is a substantial research literature documenting the efficacy of conventional antidepressants, particularly selective serotonin reuptake inhibitors (ssris), novel agents such as dehydroepiandrosterone, psychostimulants and some psychotherapies, particularly interpersonal and group psychotherapy for the treatment of depression in hiv. |
2008-03-26 |
2023-08-12 |
Not clear |