| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rinat Gizatullin, Ghazal Zaboli, Erik G Jönsson, Marie Asberg, Rosario Leopard. The tryptophan hydroxylase (TPH) 2 gene unlike TPH-1 exhibits no association with stress-induced depression. Journal of affective disorders. vol 107. issue 1-3. 2008-05-27. PMID:17692928. |
serotonin (5-ht) has been implicated in the pathophysiology of several psychiatric disorders including major depression (md). |
2008-05-27 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Lea R Dougherty, Bryan Maloney, Thomas M Olino, Haroon Sheikh, C Emily Durbin, John I Nurnberger, Debomoy K Lahiri, Daniel N Klei. Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism. Journal of affective disorders. vol 107. issue 1-3. 2008-05-27. PMID:17804080. |
early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism. |
2008-05-27 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Lea R Dougherty, Bryan Maloney, Thomas M Olino, Haroon Sheikh, C Emily Durbin, John I Nurnberger, Debomoy K Lahiri, Daniel N Klei. Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism. Journal of affective disorders. vol 107. issue 1-3. 2008-05-27. PMID:17804080. |
serotonin transporter promoter (5-httlpr) genotype appears to increase risk for depression in the context of stressful life events. |
2008-05-27 |
2023-08-12 |
Not clear |
| Eduardo Luiz Pedrazza, Eduardo Pacheco Rico, Mario Roberto Senger, Leonardo Pedrazza, Fernanda Francine Zimmermann, João José Freitas Sarkis, Maurício Reis Bogo, Carla Denise Bona. Ecto-nucleotidase pathway is altered by different treatments with fluoxetine and nortriptyline. European journal of pharmacology. vol 583. issue 1. 2008-05-27. PMID:18280468. |
selective serotonin reuptake inhibitors and tricyclic antidepressants, such as fluoxetine and nortriptyline, respectively, are commonly used in treatment for depression. |
2008-05-27 |
2023-08-12 |
Not clear |
| Karl Rickels, Sanjay Mathew, Michael D Banov, Daniel L Zimbroff, Scott Oshana, Edward C Parsons, Stephen R Donahue, Michael Kauffman, Ganesh R Iyer, John F Reinhar. Effects of PRX-00023, a novel, selective serotonin 1A receptor agonist on measures of anxiety and depression in generalized anxiety disorder: results of a double-blind, placebo-controlled trial. Journal of clinical psychopharmacology. vol 28. issue 2. 2008-05-27. PMID:18344738. |
effects of prx-00023, a novel, selective serotonin 1a receptor agonist on measures of anxiety and depression in generalized anxiety disorder: results of a double-blind, placebo-controlled trial. |
2008-05-27 |
2023-08-12 |
human |
| Russel S Falck, Jichuan Wang, Robert G Carlso. Depressive symptomatology in young adults with a history of MDMA use: a longitudinal analysis. Journal of psychopharmacology (Oxford, England). vol 22. issue 1. 2008-05-22. PMID:18187532. |
research suggests that methylenedioxymethamphetamine (mdma)/;ecstasy' can cause serotonin depletion as well as serotonergic neurodegradation that may result in depression. |
2008-05-22 |
2023-08-12 |
Not clear |
| Jordan F Karp, Ellen M Whyte, Eric J Lenze, Mary A Dew, Amy Begley, Mark D Miller, Charles F Reynold. Rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerability. The Journal of clinical psychiatry. vol 69. issue 3. 2008-05-22. PMID:18251622. |
rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerability. |
2008-05-22 |
2023-08-12 |
human |
| Yoshihisa Kitamura, Kozue Akiyama, Kouhei Kitagawa, Kazuhiko Shibata, Hiromu Kawasaki, Katsuya Suemaru, Hiroaki Araki, Toshiaki Sendo, Yutaka Gomit. Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression: involvement of 5-HT(2A) receptors? Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18255130. |
chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an acth-induced animal model of treatment-resistant depression: involvement of 5-ht(2a) receptors? |
2008-05-20 |
2023-08-12 |
rat |
| John P Christianson, Sarah Rabbett, Jennifer Lyckland, Robert C Druga. The immobility produced by intermittent swim stress is not mediated by serotonin. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18295323. |
the results of previous studies suggest that stress causes a temporary sensitization of the brain serotonin (5-ht) system that is necessary and sufficient for producing behavioral depression. |
2008-05-20 |
2023-08-12 |
Not clear |
| John P Christianson, Sarah Rabbett, Jennifer Lyckland, Robert C Druga. The immobility produced by intermittent swim stress is not mediated by serotonin. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18295323. |
these results suggested that 5-ht is not a critical mediator of iss induced behavioral depression. |
2008-05-20 |
2023-08-12 |
Not clear |
| John P Christianson, Sarah Rabbett, Jennifer Lyckland, Robert C Druga. The immobility produced by intermittent swim stress is not mediated by serotonin. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18295323. |
taken together, these experiments indicate that iss produces a significant behavioral depression manifested as increased immobility but offer no support of the hypothesis that 5-ht is a critical mediator of these effects. |
2008-05-20 |
2023-08-12 |
Not clear |
| Li-Min Yang, Bing Hu, Ying-Hong Xia, Bei-Lin Zhang, Hua Zha. Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus. Behavioural brain research. vol 188. issue 1. 2008-05-19. PMID:18054396. |
the dorsal raphe nucleus (drn)-serotonin (5-ht) system plays a key role in stress-related psychiatric disorders such as anxiety and depression. |
2008-05-19 |
2023-08-12 |
rat |
| Daniela Popa, Clément Léna, Chloé Alexandre, Joëlle Adrie. Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 14. 2008-05-19. PMID:18385313. |
lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior. |
2008-05-19 |
2023-08-12 |
mouse |
| Daniela Popa, Clément Léna, Chloé Alexandre, Joëlle Adrie. Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 14. 2008-05-19. PMID:18385313. |
here, we show that female mice treated neonatally with a highly selective serotonin reuptake inhibitor, escitalopram, exhibited signs of depression in the form of sleep anomalies, anhedonia, increased helplessness reversed by chronic antidepressant treatment, enhanced response to acute stress, and increased serotoninergic autoinhibitory feedback. |
2008-05-19 |
2023-08-12 |
mouse |
| Helen Lavretsky, Prabha Siddarth, Anand Kumar, Charles F Reynold. The effects of the dopamine and serotonin transporter polymorphisms on clinical features and treatment response in geriatric depression: a pilot study. International journal of geriatric psychiatry. vol 23. issue 1. 2008-05-12. PMID:17621383. |
the effects of the dopamine and serotonin transporter polymorphisms on clinical features and treatment response in geriatric depression: a pilot study. |
2008-05-12 |
2023-08-12 |
human |
| Lana J Williams, Margaret J Henry, Michael Berk, Seetal Dodd, Felice N Jacka, Mark A Kotowicz, Geoffrey C Nicholson, Julie A Pasc. Selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression. International clinical psychopharmacology. vol 23. issue 2. 2008-05-07. PMID:18301122. |
selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression. |
2008-05-07 |
2023-08-12 |
Not clear |
| Lana J Williams, Margaret J Henry, Michael Berk, Seetal Dodd, Felice N Jacka, Mark A Kotowicz, Geoffrey C Nicholson, Julie A Pasc. Selective serotonin reuptake inhibitor use and bone mineral density in women with a history of depression. International clinical psychopharmacology. vol 23. issue 2. 2008-05-07. PMID:18301122. |
selective serotonin reuptake inhibitors (ssris) are a first-line treatment for depression. |
2008-05-07 |
2023-08-12 |
Not clear |
| T B Henry, M C Blac. Acute and chronic toxicity of fluoxetine (selective serotonin reuptake inhibitor) in western mosquitofish. Archives of environmental contamination and toxicology. vol 54. issue 2. 2008-05-06. PMID:17763886. |
known as a selective serotonin reuptake inhibitor, fluoxetine (e.g., prozac; elli lilly) is neurologically active and widely prescribed for clinical depression in humans. |
2008-05-06 |
2023-08-12 |
Not clear |
| Rui Wang, Ying Xu, Hong-Li Wu, Ying-Bo Li, Yu-Hua Li, Jia-Bin Guo, Xue-Jun L. The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors. European journal of pharmacology. vol 578. issue 1. 2008-05-06. PMID:17942093. |
the purpose of this study was to explore the possible contribution of serotonin (5-ht) receptors in the behavioral effects induced by curcumin in this animal model of depression. |
2008-05-06 |
2023-08-12 |
Not clear |
| Janos P Kis. Theory of active antidepressants: a nonsynaptic approach to the treatment of depression. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17507113. |
according to the monoamine theory the most important neurochemical process in depression is the impairment of monoaminergic neurotransmission and the concomitant decrease of extracellular concentration of noradrenaline and/or serotonin. |
2008-05-05 |
2023-08-12 |
Not clear |