| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
these data suggest a critical role of reduced hippocampal 5-ht and npy neurotransmission in cums-induced depression. |
2008-09-11 |
2023-08-12 |
rat |
| Ping Zhong, Eunice Y Yuen, Zhen Ya. Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex. Molecular and cellular neurosciences. vol 38. issue 2. 2008-09-09. PMID:18455431. |
both serotonin and nmda signaling in prefrontal cortex (pfc) are implicated in mental disorders, including depression and anxiety. |
2008-09-09 |
2023-08-12 |
Not clear |
| Hisashi Higuchi, Kazuhiro Sato, Keizo Yoshida, Hitoshi Takahashi, Mitsuhiro Kamata, Koichi Otani, Noboru Yamaguch. Predictors of antidepressant response to fluvoxamine obtained using the three-factor structures of the Montgomery and Asberg Depression Rating Scale for major depressive disorders in Japanese patients. Psychiatry and clinical neurosciences. vol 62. issue 3. 2008-09-02. PMID:18588590. |
fluvoxamine, a selective serotonin reuptake inhibitor, is widely used to treat major depression. |
2008-09-02 |
2023-08-12 |
Not clear |
| Marina Sagud, Nela Pivac, Maja Mustapic, Gordana Nedic, Alma Mihaljevic Peles, Milivoj Kramaric, Miro Jakovljevic, Dorotea Muck-Sele. The effect of lamotrigine on platelet serotonin concentration in patients with bipolar depression. Psychopharmacology. vol 197. issue 4. 2008-08-29. PMID:18246328. |
the effect of lamotrigine on platelet serotonin concentration in patients with bipolar depression. |
2008-08-29 |
2023-08-12 |
Not clear |
| R Seethalakshmi, E S Krishnamoorth. The complex relationship between seizures and behavior: an illustrative case report. Epilepsy & behavior : E&B. vol 10. issue 1. 2008-08-28. PMID:17197245. |
we report here the interesting case of mrs. a, who presented with depression and developed seizures and an ictal psychosis precipitated by use of a selective serotonin reuptake inhibitor. |
2008-08-28 |
2023-08-12 |
Not clear |
| Thiago Santos Gouvêa, Helena K Morimoto, Maria José S S de Faria, Estefânia Gastaldello Moreira, Daniela Cristina Ceccatto Gerardi. Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18457868. |
fluoxetine (flx), a selective serotonin reuptake inhibitor (ssri) antidepressant, has been widely prescribed for depression during pregnancy and/or lactation. |
2008-08-25 |
2023-08-12 |
mouse |
| Robert A Philibert, Harinder Sandhu, Nancy Hollenbeck, Tracy Gunter, William Adams, Anup Mada. The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 5. 2008-08-19. PMID:17987668. |
the relationship of 5htt (slc6a4) methylation and genotype on mrna expression and liability to major depression and alcohol dependence in subjects from the iowa adoption studies. |
2008-08-19 |
2023-08-12 |
human |
| Yung-Tian A Gau, Ying-Jay Liou, Younger W-Y Yu, Tai-Jui Chen, Ming-Wei Lin, Shih-Jen Tsai, Chen-Jee Hon. Evidence for association between genetic variants of p75 neurotrophin receptor (p75NTR) gene and antidepressant treatment response in Chinese major depressive disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 5. 2008-08-19. PMID:18081157. |
subjects took selective serotonin reuptake inhibitors (ssris) and responders were defined as those with at least a 50% decrease in score of the hamilton rating scale for depression (ham-d) from baseline. |
2008-08-19 |
2023-08-12 |
human |
| S Weinmann, T Becker, M Koester. Re-evaluation of the efficacy and tolerability of venlafaxine vs SSRI: meta-analysis. Psychopharmacology. vol 196. issue 4. 2008-08-14. PMID:17955213. |
a number of reviews have claimed that the selective serotonin and noradrenalin re-uptake inhibitor venlafaxine is more effective than selective serotonin re-uptake inhibitors (ssris) in achieving remission and symptom reduction in major depression. |
2008-08-14 |
2023-08-12 |
Not clear |
| L Pezawas, A Meyer-Lindenberg, A L Goldman, B A Verchinski, G Chen, B S Kolachana, M F Egan, V S Mattay, A R Hariri, D R Weinberge. Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression. Molecular psychiatry. vol 13. issue 7. 2008-08-13. PMID:18347599. |
5-httlpr and bdnf val66met, functional polymorphisms of the serotonin (5-ht) transporter (slc6a4) and brain-derived neurotrophic factor (bdnf) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and plasticity of circuitries of emotion processing. |
2008-08-13 |
2023-08-12 |
mouse |
| E Kuteeva, T Hökfelt, T Wardi, S O Ogre. Galanin, galanin receptor subtypes and depression-like behaviour. Cellular and molecular life sciences : CMLS. vol 65. issue 12. 2008-08-13. PMID:18500640. |
galanin is coexpressed with and modulates noradrenaline and serotonin systems, both implicated in depression. |
2008-08-13 |
2023-08-12 |
Not clear |
| Astrid C E Linthorst, Johannes M Reu. Stress and the brain: solving the puzzle using microdialysis. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:18028991. |
the therapeutical efficacy of selective serotonin re-uptake inhibitors and benzodiazepines points to a key role of serotonin and gamma-aminobutyric acid (gaba) in depression and anxiety. |
2008-08-12 |
2023-08-12 |
human |
| K Schroecksnadel, M Sarcletti, C Winkler, B Mumelter, G Weiss, D Fuchs, G Kemmler, R Zangerl. Quality of life and immune activation in patients with HIV-infection. Brain, behavior, and immunity. vol 22. issue 6. 2008-08-12. PMID:18261883. |
as an enhanced degradation of the serotonin precursor tryptophan is well documented in hiv-infected patients, disturbances in tryptophan metabolism may be causally linked to hiv-related depression. |
2008-08-12 |
2023-08-12 |
Not clear |
| Bryan A Strange, Marijn C W Kroes, Jonathan P Roiser, Geoffrey C Y Tan, Raymond J Dola. Emotion-induced retrograde amnesia is determined by a 5-HTT genetic polymorphism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 28. 2008-08-12. PMID:18614671. |
a polymorphism in the human serotonin transporter (5-htt) gene is implicated in susceptibility to anxiety and depression and in enhanced emotion-induced activation in the amygdala. |
2008-08-12 |
2023-08-12 |
human |
| Ozlem Dogan, Nevzat Yuksel, Mehmet Ali Ergun, Akin Yilmaz, Mustafa N Ilhan, Hatice Ersin Karslioglu, Aysegul Koc, Adnan Menevs. Serotonin transporter gene polymorphisms and sertraline response in major depression patients. Genetic testing. vol 12. issue 2. 2008-08-11. PMID:18452396. |
serotonin transporter gene polymorphisms and sertraline response in major depression patients. |
2008-08-11 |
2023-08-12 |
human |
| Ghazal Zaboli, Erik G Jönsson, Rinat Gizatullin, Alessandra De Franciscis, Marie Asberg, Rosario Leopard. Haplotype analysis confirms association of the serotonin transporter (5-HTT) gene with schizophrenia but not with major depression. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147. issue 3. 2008-08-08. PMID:17886257. |
haplotype analysis confirms association of the serotonin transporter (5-htt) gene with schizophrenia but not with major depression. |
2008-08-08 |
2023-08-12 |
Not clear |
| L M Loeb, M G Naffah-Mazzacoratti, M A Porcionatto, J R M Martins, M Kouyoumdjian, L M Weckx, H B Nade. Chondroitin sulfate and kallikrein in saliva: markers for glossodynia. International immunopharmacology. vol 8. issue 7. 2008-08-07. PMID:18486918. |
depression could explain the low level of serotonin in patient serum (p=0.0478). |
2008-08-07 |
2023-08-12 |
human |
| Egemen Savaskan, Sandra E Müller, Andreas Böhringer, André Schulz, Hartmut Schächinge. Antidepressive therapy with escitalopram improves mood, cognitive symptoms, and identity memory for angry faces in elderly depressed patients. The international journal of neuropsychopharmacology. vol 11. issue 3. 2008-08-06. PMID:17697395. |
because of their good tolerability relative to the older tricyclic compounds, selective serotonin reuptake inhibitors (ssris) are increasingly used for the treatment of depression in the elderly. |
2008-08-06 |
2023-08-12 |
human |
| M Reimold, A Batra, A Knobel, M N Smolka, A Zimmer, K Mann, C Solbach, G Reischl, F Schwärzler, G Gründer, H-J Machulla, R Bares, A Hein. Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study. Molecular psychiatry. vol 13. issue 6. 2008-08-06. PMID:18268503. |
anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11c]dasb pet study. |
2008-08-06 |
2023-08-12 |
human |
| M Reimold, A Batra, A Knobel, M N Smolka, A Zimmer, K Mann, C Solbach, G Reischl, F Schwärzler, G Gründer, H-J Machulla, R Bares, A Hein. Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study. Molecular psychiatry. vol 13. issue 6. 2008-08-06. PMID:18268503. |
some in vivo imaging studies showed reduced availability of serotonin transporters (5-htt) in the brainstem and thalamus of patients with major depression. |
2008-08-06 |
2023-08-12 |
human |