| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P K McCamphill, T W Dunn, N I Sye. Serotonin modulates transmitter release at central Lymnaea synapses through a G-protein-coupled and cAMP-mediated pathway. The European journal of neuroscience. vol 27. issue 8. 2008-07-01. PMID:18412624. |
we demonstrate that either serotonin or lped1 activity-induced depression of presynaptic transmitter release from vd4 involves voltage-gated calcium channels and is mediated through a g-protein-coupled and camp-mediated system. |
2008-07-01 |
2023-08-12 |
Not clear |
| Alan J Lenox-Smith, Qin Jian. Venlafaxine extended release versus citalopram in patients with depression unresponsive to a selective serotonin reuptake inhibitor. International clinical psychopharmacology. vol 23. issue 3. 2008-06-26. PMID:18408525. |
venlafaxine extended release versus citalopram in patients with depression unresponsive to a selective serotonin reuptake inhibitor. |
2008-06-26 |
2023-08-12 |
human |
| Alan J Lenox-Smith, Qin Jian. Venlafaxine extended release versus citalopram in patients with depression unresponsive to a selective serotonin reuptake inhibitor. International clinical psychopharmacology. vol 23. issue 3. 2008-06-26. PMID:18408525. |
findings from the national institute of mental health's sequenced treatment alternatives to relieve depression trial indicate that approximately 50% of patients with major depressive disorder do not experience a treatment response after adequate first-line treatment with a selective serotonin reuptake inhibitor (ssri). |
2008-06-26 |
2023-08-12 |
human |
| Grégory Barrière, Maylis Tartas, Jean-René Cazalets, Sandrine S Bertran. Interplay between neuromodulator-induced switching of short-term plasticity at sensorimotor synapses in the neonatal rat spinal cord. The Journal of physiology. vol 586. issue 7. 2008-06-23. PMID:18258661. |
in the present study, we investigated the modulation of short-term depression (std) at synapses between sensory afferents and rat motoneurons by serotonin, dopamine and noradrenaline. |
2008-06-23 |
2023-08-12 |
rat |
| Grégory Barrière, Maylis Tartas, Jean-René Cazalets, Sandrine S Bertran. Interplay between neuromodulator-induced switching of short-term plasticity at sensorimotor synapses in the neonatal rat spinal cord. The Journal of physiology. vol 586. issue 7. 2008-06-23. PMID:18258661. |
dopamine and serotonin homogenized the degree of depression observed with the different stimulation modalities, in contrast to noradrenaline, which amplified the rate differences. |
2008-06-23 |
2023-08-12 |
rat |
| Grégory Barrière, Maylis Tartas, Jean-René Cazalets, Sandrine S Bertran. Interplay between neuromodulator-induced switching of short-term plasticity at sensorimotor synapses in the neonatal rat spinal cord. The Journal of physiology. vol 586. issue 7. 2008-06-23. PMID:18258661. |
dopamine and serotonin strongly decreased std and converted depression to facilitation at 5 and 10 hz during the blockade of the gabaergic receptors in 50% of the neurons tested. |
2008-06-23 |
2023-08-12 |
rat |
| Alexandre Berney, Masami Nishikawa, Chawki Benkelfat, Guy Debonnel, Gabriella Gobbi, Mirko Diksi. An index of 5-HT synthesis changes during early antidepressant treatment: alpha-[11C]methyl-L-tryptophan PET study. Neurochemistry international. vol 52. issue 4-5. 2008-06-20. PMID:17928105. |
using the alpha-[(11)c]methyl-l-tryptophan/positron emission tomography (pet), the goal of the present double-blind, randomized study was to compare the changes in alpha-[(11)c]methyl-l-tryptophan trapping, an index of serotonin synthesis, in patients suffering from unipolar depression treated with the ssri citalopram (20 mg/day) plus placebo versus patients treated with citalopram plus pindol (7.5 mg/day). |
2008-06-20 |
2023-08-12 |
human |
| Nicole M Sanders, Charles W Wilkinson, Gerald J Taborsky, Salwa Al-Noori, Wendi Daumen, Aryana Zavosh, Dianne P Figlewic. The selective serotonin reuptake inhibitor sertraline enhances counterregulatory responses to hypoglycemia. American journal of physiology. Endocrinology and metabolism. vol 294. issue 5. 2008-06-19. PMID:18334609. |
selective serotonin reuptake inhibitors (ssris) are widely prescribed for patients with comorbid diabetes and depression. |
2008-06-19 |
2023-08-12 |
rat |
| Hideki Miura, Norio Ozaki, Makoto Sawada, Kenichi Isobe, Tatsuro Ohta, Toshiharu Nagats. A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress (Amsterdam, Netherlands). vol 11. issue 3. 2008-06-19. PMID:18465467. |
a link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. |
2008-06-19 |
2023-08-12 |
Not clear |
| Hideki Miura, Norio Ozaki, Makoto Sawada, Kenichi Isobe, Tatsuro Ohta, Toshiharu Nagats. A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress (Amsterdam, Netherlands). vol 11. issue 3. 2008-06-19. PMID:18465467. |
the resultant decrease in 5-ht production may relate to the monoamine hypothesis of major depression. |
2008-06-19 |
2023-08-12 |
Not clear |
| Zhengming Chen, Ji Yang, Anne Toba. Designing new treatments for depression and anxiety. IDrugs : the investigational drugs journal. vol 11. issue 3. 2008-06-12. PMID:18311656. |
an important development in the treatment of depression has been the emergence of triple reuptake inhibitors (sndris), which inhibit the reuptake of serotonin, norepinephrine and dopamine. |
2008-06-12 |
2023-08-12 |
Not clear |
| M R Lemk. Depressive symptoms in Parkinson's disease. European journal of neurology. vol 15 Suppl 1. 2008-06-11. PMID:18353133. |
tricyclic and newer selective antidepressants including serotonin and noradrenaline reuptake inhibitors appear to be effective in treating depression in pd. |
2008-06-11 |
2023-08-12 |
Not clear |
| Rajamannar Ramasubbu, Rose Tobias, N Torben Bech-Hanse. Extended evaluation of serotonin transporter gene functional polymorphisms in subjects with post-stroke depression. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 53. issue 3. 2008-06-11. PMID:18441666. |
extended evaluation of serotonin transporter gene functional polymorphisms in subjects with post-stroke depression. |
2008-06-11 |
2023-08-12 |
human |
| Rajamannar Ramasubbu, Rose Tobias, N Torben Bech-Hanse. Extended evaluation of serotonin transporter gene functional polymorphisms in subjects with post-stroke depression. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 53. issue 3. 2008-06-11. PMID:18441666. |
as an extension of our previous observation, relating a serotonin transporter gene-linked promoter region (5-httlpr) diallelic functional polymorphism (short [s] and long [l] alleles) to the risk of post-stroke major depression (psd), this study investigated the role of 2 other functional polymorphisms of the serotonin transporter gene (5-htt) in the same sample of subjects with psd. |
2008-06-11 |
2023-08-12 |
human |
| Jessica Bah, Mats Lindström, Lars Westberg, Louise Mannerås, Erik Ryding, Susanne Henningsson, Jonas Melke, Ingmar Rosén, Lil Träskman-Bendz, Elias Eriksso. Serotonin transporter gene polymorphisms: effect on serotonin transporter availability in the brain of suicide attempters. Psychiatry research. vol 162. issue 3. 2008-06-10. PMID:18314311. |
the efficacy of serotonin reuptake inhibitors in depression and anxiety disorders suggests the gene coding for the serotonin transporter (5-htt), slc6a4, as a candidate of importance for these conditions. |
2008-06-10 |
2023-08-12 |
Not clear |
| Dorian Deshauer, David Moher, Dean Fergusson, Ester Moher, Margaret Sampson, Jeremy Grimsha. Selective serotonin reuptake inhibitors for unipolar depression: a systematic review of classic long-term randomized controlled trials. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. vol 178. issue 10. 2008-06-03. PMID:18458261. |
selective serotonin reuptake inhibitors for unipolar depression: a systematic review of classic long-term randomized controlled trials. |
2008-06-03 |
2023-08-12 |
Not clear |
| Dorian Deshauer, David Moher, Dean Fergusson, Ester Moher, Margaret Sampson, Jeremy Grimsha. Selective serotonin reuptake inhibitors for unipolar depression: a systematic review of classic long-term randomized controlled trials. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. vol 178. issue 10. 2008-06-03. PMID:18458261. |
selective serotonin reuptake inhibitors are increasingly used in the long-term treatment of depression. |
2008-06-03 |
2023-08-12 |
Not clear |
| Dorian Deshauer, David Moher, Dean Fergusson, Ester Moher, Margaret Sampson, Jeremy Grimsha. Selective serotonin reuptake inhibitors for unipolar depression: a systematic review of classic long-term randomized controlled trials. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. vol 178. issue 10. 2008-06-03. PMID:18458261. |
we conducted a systematic review to examine the efficacy and acceptability of long-term therapy with selective serotonin reuptake inhibitors relative to placebo in the treatment of unipolar depression. |
2008-06-03 |
2023-08-12 |
Not clear |
| Francis E Lotrich, Bruce G Pollock, Margaret Kirshner, Robert F Ferrell, Charles F Reynolds Ii. Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients. Journal of psychiatry & neuroscience : JPN. vol 33. issue 2. 2008-05-30. PMID:18330458. |
serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients. |
2008-05-30 |
2023-08-12 |
Not clear |
| Hymie Anisman, Lisheng Du, Mikos Palkovits, Gabor Faludi, Gabor G Kovacs, Peter Szontagh-Kishazi, Zul Merali, Michael O Poulte. Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects. Journal of psychiatry & neuroscience : JPN. vol 33. issue 2. 2008-05-30. PMID:18330459. |
studies comparing people suffering from depression who committed suicide with control subjects have yielded inconsistent results regarding serotonin (5-ht) involvement in pathology, possibly owing to procedural factors. |
2008-05-30 |
2023-08-12 |
human |