| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David A Barton, Murray D Esler, Tye Dawood, Elisabeth A Lambert, Deepak Haikerwal, Celia Brenchley, Florentia Socratous, Jacqueline Hastings, Ling Guo, Glen Wiesner, David M Kaye, Richard Bayles, Markus P Schlaich, Gavin W Lamber. Elevated brain serotonin turnover in patients with depression: effect of genotype and therapy. Archives of general psychiatry. vol 65. issue 1. 2008-01-14. PMID:18180427. |
elevated brain serotonin turnover in patients with depression: effect of genotype and therapy. |
2008-01-14 |
2023-08-12 |
Not clear |
| E Hame. Serotonin and migraine: biology and clinical implications. Cephalalgia : an international journal of headache. vol 27. issue 11. 2008-01-10. PMID:17970989. |
although the exact cascade of events that link abnormal serotonergic neurotransmission to the manifestation of head pain and the accompanying symptoms has yet to be fully understood, recent evidence suggests that a low 5-ht state facilitates activation of the trigeminovascular nociceptive pathway, as induced by cortical spreading depression. |
2008-01-10 |
2023-08-12 |
Not clear |
| N Müller, M J Schwar. The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression. Molecular psychiatry. vol 12. issue 11. 2008-01-09. PMID:17457312. |
the immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression. |
2008-01-09 |
2023-08-12 |
Not clear |
| Akira Sakurai, Robert J Calin-Jageman, Paul S Kat. Potentiation phase of spike timing-dependent neuromodulation by a serotonergic interneuron involves an increase in the fraction of transmitter release. Journal of neurophysiology. vol 98. issue 4. 2008-01-08. PMID:17686912. |
in the presence of 4-aminopyridine, which blocks the depression phase and enhances transmitter release from vsi, rapidly stimulating vsi led to a steady-state level of transmitter depletion during which potentiation by dsi or serotonin (5-ht) was eliminated. |
2008-01-08 |
2023-08-12 |
Not clear |
| Emily R Filter, Laura Gorczynski, John R Fernande. Fatal intoxication with a selective serotonin reuptake inhibitor, lorazepam, and codeine. The American journal of forensic medicine and pathology. vol 28. issue 4. 2008-01-07. PMID:18043028. |
selective serotonin reuptake inhibitors were introduced in 1987 as an alternative treatment option for patients with depression or certain anxiety disorders. |
2008-01-07 |
2023-08-12 |
Not clear |
| Turhan Canli, Klaus-Peter Lesc. Long story short: the serotonin transporter in emotion regulation and social cognition. Nature neuroscience. vol 10. issue 9. 2008-01-04. PMID:17726476. |
the gene encoding the serotonin transporter (5-htt) contains a regulatory variation that has been associated with anxiety-related traits and susceptibility for depression. |
2008-01-04 |
2023-08-12 |
Not clear |
| Alexander Sartorius, Fritz A Hen. Deep brain stimulation of the lateral habenula in treatment resistant major depression. Medical hypotheses. vol 69. issue 6. 2008-01-03. PMID:17498883. |
modern theories about the pathophysiology of depression are derived from studies examining the mechanism of antidepressants influencing the serotonergic (5-ht) and noradrenergic (ne) systems. |
2008-01-03 |
2023-08-12 |
human |
| Federico Remes Lenicov, Sylvie Lemonde, Margaret Czesak, Tera M Mosher, Paul R Alber. Cell-type specific induction of tryptophan hydroxylase-2 transcription by calcium mobilization. Journal of neurochemistry. vol 103. issue 5. 2008-01-03. PMID:17868301. |
alterations in brain serotonin levels are implicated in major depression and are regulated by tryptophan hydroxylase-2 (tph2). |
2008-01-03 |
2023-08-12 |
rat |
| David M Wood, Yadhunanthanan Rajalingam, Shaun L Greene, Phillip E Morgan, David Gerrie, Alison L Jones, Paul I Darga. Status epilepticus following intentional overdose of fluvoxamine: a case report with serum fluvoxamine concentration. Clinical toxicology (Philadelphia, Pa.). vol 45. issue 7. 2008-01-03. PMID:17952747. |
fluvoxamine is a selective serotonin reuptake inhibitor (ssri) that is used in the management of depression and obsessive compulsive disorders. |
2008-01-03 |
2023-08-12 |
Not clear |
| Bella Smolin, Ehud Klein, Yishai Levy, Dorit Ben-Shacha. Major depression as a disorder of serotonin resistance: inference from diabetes mellitus type II. The international journal of neuropsychopharmacology. vol 10. issue 6. 2008-01-02. PMID:17250776. |
major depression as a disorder of serotonin resistance: inference from diabetes mellitus type ii. |
2008-01-02 |
2023-08-12 |
human |
| Paôlla Freitas Perdigão, André Luiz Sena Guimarães, Junia Maria Netto Victoria, Guilherme Machado Xavier, Marco Aurélio Romano-Silva, Ricardo Santiago Gome. Serotonin transporter gene polymorphism (5-HTTLPR) in patients with oral lichen planus. Archives of oral biology. vol 52. issue 9. 2008-01-02. PMID:17359932. |
recent findings have demonstrated that depression and stress are influenced by polymorphism of the promoter region of 5-htt (5-httlpr) and that the short allele (s) is associated with reduced transcriptional efficiency resulting in reduced serotonin expression and uptake. |
2008-01-02 |
2023-08-12 |
human |
| Michael W Jann, Julian H Slad. Antidepressant agents for the treatment of chronic pain and depression. Pharmacotherapy. vol 27. issue 11. 2007-12-20. PMID:17963465. |
both serotonin and norepinephrine are also key neurotransmitters involved with the pathophysiology of depression. |
2007-12-20 |
2023-08-12 |
Not clear |
| Michael W Jann, Julian H Slad. Antidepressant agents for the treatment of chronic pain and depression. Pharmacotherapy. vol 27. issue 11. 2007-12-20. PMID:17963465. |
tricyclic antidepressants are effective treatments for pain and depression; selective serotonin reuptake inhibitors provide less benefit. |
2007-12-20 |
2023-08-12 |
Not clear |
| Ya-Chen Tina Shih, Nebiyou B Bekele, Ying X. Use of Bayesian net benefit regression model to examine the impact of generic drug entry on the cost effectiveness of selective serotonin reuptake inhibitors in elderly depressed patients. PharmacoEconomics. vol 25. issue 10. 2007-12-19. PMID:17887806. |
since their invention in the late 1980s and early 1990s, selective serotonin reuptake inhibitors (ssris) have become the primary form of pharmaceutical treatment for depression. |
2007-12-19 |
2023-08-12 |
Not clear |
| K B Thor, M Kirby, L Viktru. Serotonin and noradrenaline involvement in urinary incontinence, depression and pain: scientific basis for overlapping clinical efficacy from a single drug, duloxetine. International journal of clinical practice. vol 61. issue 8. 2007-12-14. PMID:17608681. |
serotonin and noradrenaline involvement in urinary incontinence, depression and pain: scientific basis for overlapping clinical efficacy from a single drug, duloxetine. |
2007-12-14 |
2023-08-12 |
Not clear |
| Zola N Mannie, Greg C Bristow, Catherine J Harmer, Philip J Cowe. Impaired emotional categorisation in young people at increased familial risk of depression. Neuropsychologia. vol 45. issue 13. 2007-12-13. PMID:17659308. |
we also assessed whether task performance and the influence of parental depression are modified by allelic variation in the serotonin transporter (5htt) gene. |
2007-12-13 |
2023-08-12 |
human |
| Dean G Kilpatrick, Karestan C Koenen, Kenneth J Ruggiero, Ron Acierno, Sandro Galea, Heidi S Resnick, John Roitzsch, John Boyle, Joel Gelernte. The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. The American journal of psychiatry. vol 164. issue 11. 2007-12-07. PMID:17974934. |
the serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. |
2007-12-07 |
2023-08-12 |
Not clear |
| Dean G Kilpatrick, Karestan C Koenen, Kenneth J Ruggiero, Ron Acierno, Sandro Galea, Heidi S Resnick, John Roitzsch, John Boyle, Joel Gelernte. The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. The American journal of psychiatry. vol 164. issue 11. 2007-12-07. PMID:17974934. |
the authors tested the hypothesis that a polymorphism in the serotonin transporter gene (locus, slc6a4; variant, serotonin 5-httlpr) moderates risk of posthurricane ptsd and major depression given high hurricane exposure and low social support. |
2007-12-07 |
2023-08-12 |
Not clear |
| Leslie S Kersun, Josephine Eli. Depressive symptoms and SSRI use in pediatric oncology patients. Pediatric blood & cancer. vol 49. issue 7. 2007-12-06. PMID:17437286. |
this review of depressive symptoms in pediatric cancer patients describes the challenge of recognizing depression in this group, prevalence, risk factors, and treatment, primarily with the selective serotonin reuptake inhibitors (ssris). |
2007-12-06 |
2023-08-12 |
Not clear |
| Eduardo Luiz Pedrazza, Mario Roberto Senger, Eduardo Pacheco Rico, Fernanda Francine Zimmermann, Leonardo Pedrazza, João José de Freitas Sarkis, Carla Denise Bona. Fluoxetine and nortriptyline affect NTPDase and 5'-nucleotidase activities in rat blood serum. Life sciences. vol 81. issue 15. 2007-12-06. PMID:17889906. |
selective serotonin reuptake inhibitors and tricyclic antidepressants, such as fluoxetine and nortriptyline, respectively, were commonly used in treatment for depression. |
2007-12-06 |
2023-08-12 |
rat |