| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L N Cornelisse, J E Van der Harst, J C Lodder, P J J Baarendse, A J Timmerman, H D Mansvelder, B M Spruijt, A B Brussaar. Reduced 5-HT1A- and GABAB receptor function in dorsal raphé neurons upon chronic fluoxetine treatment of socially stressed rats. Journal of neurophysiology. vol 98. issue 1. 2007-10-02. PMID:17460100. |
thus our data show that symptoms of depression after social stress are not paralleled by changes in 5-ht(1a) receptor signaling in drn neurons, but ssri treatment can alleviate these behavioral symptoms while acting strongly on the 5-ht(1a) receptor signaling pathway. |
2007-10-02 |
2023-08-12 |
rat |
| Kari A Martin, Lois E Krahn, Vijayan Balan, Marianne J Rosat. Selective serotonin reuptake inhibitors in the context of hepatitis C infection: reexamining the risks of bleeding. The Journal of clinical psychiatry. vol 68. issue 7. 2007-09-28. PMID:17685737. |
selective serotonin reuptake inhibitors (ssris) are used to treat interferon-associated depression in patients receiving hepatitis c virus therapy. |
2007-09-28 |
2023-08-12 |
Not clear |
| Guang Qiu, Daiga M Helmeste, Asanka N Samaranayake, Wui-Man Lau, Tatia M C Lee, Siu-Wa Tang, Kwok-Fai S. Modulation of the suppressive effect of corticosterone on adult rat hippocampal cell proliferation by paroxetine. Neuroscience bulletin. vol 23. issue 3. 2007-09-26. PMID:17612590. |
paroxetine, a selective serotonin reuptake transporter, is a commonly used antidepressant for alleviation of signs and symptoms of clinical depression. |
2007-09-26 |
2023-08-12 |
rat |
| J A Cervilla, E Molina, M Rivera, F Torres-González, J A Bellón, B Moreno, J D Luna, J A Lorente, F Mayoral, M King, I Nazareth, B Gutiérre. The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort. Molecular psychiatry. vol 12. issue 8. 2007-09-25. PMID:17387319. |
the risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5httlpr genotype: evidence from the spanish predict-gene cohort. |
2007-09-25 |
2023-08-12 |
human |
| J A Cervilla, E Molina, M Rivera, F Torres-González, J A Bellón, B Moreno, J D Luna, J A Lorente, F Mayoral, M King, I Nazareth, B Gutiérre. The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort. Molecular psychiatry. vol 12. issue 8. 2007-09-25. PMID:17387319. |
we tested the potential gene-by-environment interaction between 5httlpr genotype at the serotonin transporter gene and previous exposure to threatening life events (tles) in depression. |
2007-09-25 |
2023-08-12 |
human |
| Kimberly R Tyeryar, Ashiwel S Undi. Tandem regulation of phosphoinositide signaling and acute behavioral effects induced by antidepressant agents in rats. Psychopharmacology. vol 193. issue 2. 2007-09-20. PMID:17435992. |
serotonin 5ht(2) receptors, implicated in depression or the actions of some antidepressants, signal through phosphoinositide hydrolysis. |
2007-09-20 |
2023-08-12 |
rat |
| J M Scheid, C B Holzman, N Jones, K H Friderici, K A Nummy, L L Symonds, A Sikorskii, M K Regier, R Fishe. Depressive symptoms in mid-pregnancy, lifetime stressors and the 5-HTTLPR genotype. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:16965382. |
few studies of gene-environment interactions for the serotonin transporter promoter polymorphism (5-httlpr), life stressors and depression have considered women separately or examined specific types of stressful life events. |
2007-09-19 |
2023-08-12 |
human |
| Christel M Middeldorp, Eco J C de Geus, A Leo Beem, Nico Lakenberg, Jouke-Jan Hottenga, P Eline Slagboom, Dorret I Boomsm. Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression. Behavior genetics. vol 37. issue 2. 2007-09-18. PMID:17216342. |
family based association analyses between the serotonin transporter gene polymorphism (5-httlpr) and neuroticism, anxiety and depression. |
2007-09-18 |
2023-08-12 |
human |
| Christel M Middeldorp, Eco J C de Geus, A Leo Beem, Nico Lakenberg, Jouke-Jan Hottenga, P Eline Slagboom, Dorret I Boomsm. Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression. Behavior genetics. vol 37. issue 2. 2007-09-18. PMID:17216342. |
we studied the association between the short/long promotor-based length polymorphism of the serotonin transporter gene (5-httlpr) and neuroticism, anxiety and depression. |
2007-09-18 |
2023-08-12 |
human |
| Tomas Palomo, Trevor Archer, Richard M Kostrzewa, Richard J Beninge. Comorbidity of substance abuse with other psychiatric disorders. Neurotoxicity research. vol 12. issue 1. 2007-09-18. PMID:17513197. |
withdrawal from substance abuse and depression both have been linked to changes in the function of several neurotransmitters including serotonin, dopamine and glutamate. |
2007-09-18 |
2023-08-12 |
Not clear |
| L A W Jans, C K J Lieben, A Bloklan. Influence of sex and estrous cycle on the effects of acute tryptophan depletion induced by a gelatin-based mixture in adult Wistar rats. Neuroscience. vol 147. issue 2. 2007-09-18. PMID:17531394. |
serotonergic vulnerability entails that differences between people in the regulation of serotonin (5-ht) determine the vulnerability of an individual to develop depression or other 5-ht-related disorders. |
2007-09-18 |
2023-08-12 |
rat |
| Gary M Levin, Toya M Bowles, Megan J Ehret, Taimour Langaee, Jennifer Y Tan, Julie A Johnson, William J Millar. Assessment of human serotonin 1A receptor polymorphisms and SSRI responsiveness. Molecular diagnosis & therapy. vol 11. issue 3. 2007-09-14. PMID:17570737. |
roughly one-third of patients with depression do not respond to an initial trial of antidepressant medication treatment, possibly as a result of structural variations in the 5-ht(1a) receptor. |
2007-09-14 |
2023-08-12 |
human |
| Zhengming Chen, Phil Skolnic. Triple uptake inhibitors: therapeutic potential in depression and beyond. Expert opinion on investigational drugs. vol 16. issue 9. 2007-09-14. PMID:17714023. |
an important recent development has been the emergence of the triple uptake inhibitors (ssri/snri/selective dopamine reuptake inhibitor), which inhibit the uptake of all three neurotransmitters that are most closely linked to depression: serotonin, noradrenaline and dopamine. |
2007-09-14 |
2023-08-12 |
Not clear |
| b' G Bjelakovi\\xc4\\x87, S Beninati, D Pavlovi\\xc4\\x87, G Koci\\xc4\\x87, T Jevtovi\\xc4\\x87, B Kamenov, L J Saranac, B Bjelakovi\\xc4\\x87, I Stojanovi\\xc4\\x87, J Basi\\xc4\\x8. Glucocorticoids and oxidative stress. Journal of basic and clinical physiology and pharmacology. vol 18. issue 2. 2007-09-11. PMID:17715567.' |
humans and animals with gc-induced hypertension exhibit reduced nitric oxide levels; patients with excess gc levels also suffer from depression as a consequence of low levels of serotonin and melatonin. |
2007-09-11 |
2023-08-12 |
Not clear |
| Thomas I F H Cremers, Kieran Rea, Fokko J Bosker, Håkan V Wikström, Sandra Hogg, Arne Mørk, Ben H C Westerin. Augmentation of SSRI effects on serotonin by 5-HT2C antagonists: mechanistic studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 7. 2007-08-31. PMID:17203017. |
the treatment of depression may be improved by using an augmentation approach involving selective serotonin reuptake inhibitors (ssris) in combination with compounds that focus on antagonism of inhibitory serotonin receptors. |
2007-08-31 |
2023-08-12 |
Not clear |
| Esther Berrocoso, Juan Antonio Mic. In vivo effect of venlafaxine on locus coeruleus neurons: role of opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine(1A) receptors. The Journal of pharmacology and experimental therapeutics. vol 322. issue 1. 2007-08-30. PMID:17431134. |
the locus coeruleus (lc) is involved in several neural pathways responsible for some somatic and emotional processes, such as pain and depression; its activity is regulated by several receptors, such as opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine (5-ht)(1a) receptors. |
2007-08-30 |
2023-08-12 |
Not clear |
| A Shaldubina, R Buccafusca, R A Johanson, G Agam, R H Belmaker, G T Berry, Y Bersudsk. Behavioural phenotyping of sodium-myo-inositol cotransporter heterozygous knockout mice with reduced brain inositol. Genes, brain, and behavior. vol 6. issue 3. 2007-08-29. PMID:16848785. |
inositol plays a key role in dopamine, serotonin, noradrenaline and acetylcholine neurotransmission, and inositol treatment is reported to have beneficial effects in depression and anxiety. |
2007-08-29 |
2023-08-12 |
mouse |
| Tom K Birkenhäger, Walter W van den Broek, Durk Fekkes, Paul G Mulder, Peter Moleman, Jan A Bruij. Lithium addition in antidepressant-resistant depression: effects on platelet 5-HT, plasma 5-HT and plasma 5-HIAA concentration. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 5. 2007-08-28. PMID:17467132. |
lithium addition in antidepressant-resistant depression: effects on platelet 5-ht, plasma 5-ht and plasma 5-hiaa concentration. |
2007-08-28 |
2023-08-12 |
Not clear |
| Michael E Thas. Recognition and diagnosis of atypical depression. The Journal of clinical psychiatry. vol 68 Suppl 8. 2007-08-27. PMID:17640153. |
the utility of the atypical depression subtype for differential therapeutics diminished substantially when the tcas were supplanted as first-line antidepressants by the selective serotonin reuptake inhibitors. |
2007-08-27 |
2023-08-12 |
Not clear |
| C Neill Epperson, Zenab Amin, Frederick Naftolin, Angela Cappiello, Kathryn A Czarkowski, Stephanie Stiklus, George M Anderson, John H Krysta. The resistance to depressive relapse in menopausal women undergoing tryptophan depletion: preliminary findings. Journal of psychopharmacology (Oxford, England). vol 21. issue 4. 2007-08-24. PMID:16891341. |
menopausal women whose depression was responsive to treatment with oestradiol, the selective serotonin reuptake inhibitor fluoxetine, or a combination of both treatments underwent assessment of mood and verbal memory on active tryptophan depletion and sham depletion test days. |
2007-08-24 |
2023-08-12 |
human |