| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jae-Min Kim, Robert Stewart, Sung-Wan Kim, Su-Jin Yang, Il-Seon Shin, Young-Hoon Kim, Jin-Sang Yoo. Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders. Biological psychiatry. vol 62. issue 5. 2007-10-26. PMID:17482146. |
it has been reported that the functional polymorphism in the serotonin transporter gene linked promoter region (5-httlpr) modifies the association between stressful life events (sles) and depression in child, adolescent, and adult populations. |
2007-10-26 |
2023-08-12 |
Not clear |
| b' Ricard Navin\\xc3\\xa9s, Esther G\\xc3\\xb3mez-Gil, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, Gin\\xc3\\xa9s Escolar, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Hormonal response to buspirone is not impaired in major depression. Human psychopharmacology. vol 22. issue 6. 2007-10-23. PMID:17563921.' |
it has been suggested that interactions between hypothalamic pituitary adrenal (hpa) axis and serotonin-1a (5-ht(1a)) receptor system are involved in the pathophysiology of major depression. |
2007-10-23 |
2023-08-12 |
Not clear |
| b' Ricard Navin\\xc3\\xa9s, Esther G\\xc3\\xb3mez-Gil, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, Gin\\xc3\\xa9s Escolar, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Hormonal response to buspirone is not impaired in major depression. Human psychopharmacology. vol 22. issue 6. 2007-10-23. PMID:17563921.' |
a cross-sectional case-control study was designed to assess the effect of the 5-ht(1a) receptor agonist, buspirone, on 5-ht(1a) receptor function in 30 patients with major depression (dsm-iv) and in 30 age- and sex-matched healthy controls. |
2007-10-23 |
2023-08-12 |
Not clear |
| b' Ricard Navin\\xc3\\xa9s, Esther G\\xc3\\xb3mez-Gil, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, Gin\\xc3\\xa9s Escolar, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Hormonal response to buspirone is not impaired in major depression. Human psychopharmacology. vol 22. issue 6. 2007-10-23. PMID:17563921.' |
therefore, this study does not support the hypothesis of an altered postsynaptic 5-ht(1a) receptor function in major depression. |
2007-10-23 |
2023-08-12 |
Not clear |
| Elizabeth B Weller, Sheridan Tucker, Ronald A Welle. The selective serotonin reuptake inhibitors controversy in the treatment of depression in children. Current psychiatry reports. vol 7. issue 2. 2007-10-18. PMID:15802083. |
the selective serotonin reuptake inhibitors controversy in the treatment of depression in children. |
2007-10-18 |
2023-08-12 |
Not clear |
| Douglas F Levinso. Meta-analysis in psychiatric genetics. Current psychiatry reports. vol 7. issue 2. 2007-10-18. PMID:15802092. |
the 5-httlpr polymorphism in the serotonin transporter gene (slc6a4) may contribute to the risk of bipolar disorder, suicidal behavior, and neuroticism, but association to the lifetime risk of major depression has not been shown. |
2007-10-18 |
2023-08-12 |
Not clear |
| Lynn G Kirby, Yu-Zhen Pan, Emily Freeman-Daniels, Shobha Rani, John D Nunan, Adaure Akanwa, Sheryl G Bec. Cellular effects of swim stress in the dorsal raphe nucleus. Psychoneuroendocrinology. vol 32. issue 6. 2007-10-18. PMID:17602840. |
these cellular changes may contribute to the complex effects of swim stress on 5-ht neurotransmission and/or the behavioral changes underlying the forced swimming test model of depression. |
2007-10-18 |
2023-08-12 |
rat |
| P Dorado, E M Peñas-Lledó, A P González, M C Cáceres, J Cobaleda, A Lleren. Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele. Fundamental & clinical pharmacology. vol 21. issue 4. 2007-10-18. PMID:17635185. |
increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-httlpr-s) and the cyp2c9*3 allele. |
2007-10-18 |
2023-08-12 |
human |
| P Dorado, E M Peñas-Lledó, A P González, M C Cáceres, J Cobaleda, A Lleren. Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele. Fundamental & clinical pharmacology. vol 21. issue 4. 2007-10-18. PMID:17635185. |
in the present study, we aimed to analyze the potential relevance of the polymorphism in the promoter region of the serotonin transporter (sert or 5-htt) gene (5-httlpr) and the risk of suffering major depression (mdd) in a population of patients previously genotyped for cyp2c9. |
2007-10-18 |
2023-08-12 |
human |
| J R Geddes, N Freemantle, J Mason, M P Eccles, J Boynto. WITHDRAWN: Selective serotonin reuptake inhibitors (SSRIs) versus other antidepressants for depression. The Cochrane database of systematic reviews. issue 3. 2007-10-18. PMID:17636689. |
withdrawn: selective serotonin reuptake inhibitors (ssris) versus other antidepressants for depression. |
2007-10-18 |
2023-08-12 |
Not clear |
| David B Matchar, Mugdha E Thakur, Iris Grossman, Douglas C McCrory, Lori A Orlando, David C Steffens, David B Goldstein, Kathryn E Cline, Rebecca N Gra. Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs). Evidence report/technology assessment. issue 146. 2007-10-16. PMID:17764209. |
testing for cytochrome p450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (ssris). |
2007-10-16 |
2023-08-12 |
Not clear |
| David B Matchar, Mugdha E Thakur, Iris Grossman, Douglas C McCrory, Lori A Orlando, David C Steffens, David B Goldstein, Kathryn E Cline, Rebecca N Gra. Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs). Evidence report/technology assessment. issue 146. 2007-10-16. PMID:17764209. |
to determine if testing for cytochrome p450 (cyp450) polymorphisms in adults entering selective serotonin reuptake inhibitor (ssri) treatment for non-psychotic depression leads to improvement in outcomes, or if testing results are useful in medical, personal, or public health decisionmaking. |
2007-10-16 |
2023-08-12 |
Not clear |
| Christian Otte, Jeanne McCaffery, Sadia Ali, Mary A Whoole. Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study. The American journal of psychiatry. vol 164. issue 9. 2007-10-09. PMID:17728423. |
the short allele of a functional polymorphism in the promoter region of the serotonin transporter gene (5-httlpr) has been shown to interact with stressful life events to predict depression in otherwise healthy individuals. |
2007-10-09 |
2023-08-12 |
Not clear |
| David Nutt, Koen Demyttenaere, Zoltan Janka, Trond Aarre, Michel Bourin, Pier Luigi Canonico, Jose Luis Carrasco, Steven Stah. The other face of depression, reduced positive affect: the role of catecholamines in causation and cure. Journal of psychopharmacology (Oxford, England). vol 21. issue 5. 2007-10-04. PMID:17050654. |
despite significant advances in pharmacologic therapy of depression over the past two decades, a substantial proportion of patients fail to respond or experience only partial response to serotonin re-uptake inhibitor antidepressants, resulting in chronic functional impairment. |
2007-10-04 |
2023-08-12 |
Not clear |
| Christine Firk, C Rob Marku. Review: Serotonin by stress interaction: a susceptibility factor for the development of depression? Journal of psychopharmacology (Oxford, England). vol 21. issue 5. 2007-10-04. PMID:17446201. |
review: serotonin by stress interaction: a susceptibility factor for the development of depression? |
2007-10-04 |
2023-08-12 |
Not clear |
| Christine Firk, C Rob Marku. Review: Serotonin by stress interaction: a susceptibility factor for the development of depression? Journal of psychopharmacology (Oxford, England). vol 21. issue 5. 2007-10-04. PMID:17446201. |
a major problem, however, is that the role of brain 5-ht in depression is complex and this serotonin-related innate vulnerability, by itself, is not sufficient enough to cause a depressive episode. |
2007-10-04 |
2023-08-12 |
Not clear |
| Christine Firk, C Rob Marku. Review: Serotonin by stress interaction: a susceptibility factor for the development of depression? Journal of psychopharmacology (Oxford, England). vol 21. issue 5. 2007-10-04. PMID:17446201. |
in the current review, we argue that healthy individuals with a positive family history of depression are more prone to develop depression due to a genetic 5-ht susceptibility, which deteriorates stress coping mechanisms and increases stress vulnerability. |
2007-10-04 |
2023-08-12 |
Not clear |
| K Sas, K Csete, Z Vezekényi, L Sztriha, L Vécseil, J G Pap. Effects of citalopram and fluoxetine on the corticocerebral blood flow in conscious rabbits. Acta physiologica Hungarica. vol 94. issue 3. 2007-10-04. PMID:17853768. |
selective serotonin reuptake inhibitory drugs (ssris) as antidepressants, are well tolerated, and also seem to be effective in post-stroke depression. |
2007-10-04 |
2023-08-12 |
Not clear |
| L N Cornelisse, J E Van der Harst, J C Lodder, P J J Baarendse, A J Timmerman, H D Mansvelder, B M Spruijt, A B Brussaar. Reduced 5-HT1A- and GABAB receptor function in dorsal raphé neurons upon chronic fluoxetine treatment of socially stressed rats. Journal of neurophysiology. vol 98. issue 1. 2007-10-02. PMID:17460100. |
autoinhibitory serotonin 1a receptors (5-ht(1a)) in dorsal raphé nucleus (drn) have been implicated in chronic depression and in actions of selective serotonin reuptake inhibitors (ssri). |
2007-10-02 |
2023-08-12 |
rat |
| L N Cornelisse, J E Van der Harst, J C Lodder, P J J Baarendse, A J Timmerman, H D Mansvelder, B M Spruijt, A B Brussaar. Reduced 5-HT1A- and GABAB receptor function in dorsal raphé neurons upon chronic fluoxetine treatment of socially stressed rats. Journal of neurophysiology. vol 98. issue 1. 2007-10-02. PMID:17460100. |
due to experimental limitations, it was never studied at single-cell level whether changes in 5-ht(1a) receptor functionality occur in depression and during ssri treatment. |
2007-10-02 |
2023-08-12 |
rat |