| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Khanh Q Nguyen, Yoshihiro Tohyama, Arata Watanabe, Shu Hasegawa, Ivan Skelin, Mirko Diksi. Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19073228. |
pindolol acceleration and augmentation of ssri antidepressant therapy for human depression may be mediated by attenuation of 5-ht(1a/b) autoreceptor feedback, permitting unhindered ssri effects on serotonergic terminals. |
2009-07-28 |
2023-08-12 |
human |
| Kyoko Nishi, Kazuya Kanemaru, Shu Hasegawa, Arata Watanabe, Mirko Diksi. Both acute and chronic buspirone treatments have different effects on regional 5-HT synthesis in Flinders Sensitive Line rats (a rat model of depression) than in control rats. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19084042. |
both acute and chronic buspirone treatments have different effects on regional 5-ht synthesis in flinders sensitive line rats (a rat model of depression) than in control rats. |
2009-07-28 |
2023-08-12 |
rat |
| Kyoko Nishi, Kazuya Kanemaru, Mirko Diksi. A genetic rat model of depression, Flinders sensitive line, has a lower density of 5-HT(1A) receptors, but a higher density of 5-HT(1B) receptors, compared to control rats. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19121358. |
deficiencies in brain serotonergic neurotransmission, which is in part associated with the alteration of brain serotonin (5-ht) receptors, have been proposed as part of a neurochemical imbalance in affective disorders, including depression. |
2009-07-28 |
2023-08-12 |
human |
| Kyoko Nishi, Kazuya Kanemaru, Mirko Diksi. A genetic rat model of depression, Flinders sensitive line, has a lower density of 5-HT(1A) receptors, but a higher density of 5-HT(1B) receptors, compared to control rats. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19121358. |
however, comparisons, particularly of neurochemical and/or biological parameters in frl rats, may reveal new insight into the alterations of 5-ht neurotransmission in this animal model of depression and possibly human depression, as well as the elevation of symptoms with treatments. |
2009-07-28 |
2023-08-12 |
human |
| T Kendrick, J Chatwin, C Dowrick, A Tylee, R Morriss, R Peveler, M Leese, P McCrone, T Harris, M Moore, R Byng, G Brown, S Barthel, H Mander, A Ring, V Kelly, V Wallace, M Gabbay, T Craig, A Man. Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study. Health technology assessment (Winchester, England). vol 13. issue 22. 2009-07-28. PMID:19401066. |
randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the thread (threshold for antidepressant response) study. |
2009-07-28 |
2023-08-12 |
Not clear |
| T Kendrick, J Chatwin, C Dowrick, A Tylee, R Morriss, R Peveler, M Leese, P McCrone, T Harris, M Moore, R Byng, G Brown, S Barthel, H Mander, A Ring, V Kelly, V Wallace, M Gabbay, T Craig, A Man. Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study. Health technology assessment (Winchester, England). vol 13. issue 22. 2009-07-28. PMID:19401066. |
to determine (1) the effectiveness and cost-effectiveness of selective serotonin reuptake inhibitor (ssri) treatment plus supportive care, versus supportive care alone, for mild to moderate depression in patients with somatic symptoms in primary care; and (2) the impact of the initial severity of depression on effectiveness and relative costs. |
2009-07-28 |
2023-08-12 |
Not clear |
| Norma Pavía Ruz, Laura Civeira González, Arsenio Rosado Franc. [Syndrome premenstrual dysphoric 185 preschool teachers in Mérida Yucatán]. Ginecologia y obstetricia de Mexico. vol 77. issue 4. 2009-07-28. PMID:19496510. |
this syndrome increases the risk of: major depressive disorder, postpartum depression and other serotonin spectrum pictures. |
2009-07-28 |
2023-08-12 |
Not clear |
| Josephine Arendt, Shantha M W Rajaratna. Melatonin and its agonists: an update. The British journal of psychiatry : the journal of mental science. vol 193. issue 4. 2009-07-27. PMID:18827285. |
depression is specifically targeted by agomelatine, which is also a serotonin-2c (5-ht(2c)) antagonist. |
2009-07-27 |
2023-08-12 |
Not clear |
| Donna L Maier, Cindy Sobotka-Briner, Min Ding, Mark E Powell, Qiaoling Jiang, Geraldine Hill, J Richard Heys, Charles S Elmore, M Edward Pierson, Ladislav Mrzlja. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy. The Journal of pharmacology and experimental therapeutics. vol 330. issue 1. 2009-07-27. PMID:19401496. |
in psychiatry, 5-ht(1b) antagonists may provide novel therapeutics for depression and anxiety. |
2009-07-27 |
2023-08-12 |
human |
| Benedetto Vitiell. Combined cognitive-behavioural therapy and pharmacotherapy for adolescent depression: Does it improve outcomes compared with monotherapy? CNS drugs. vol 23. issue 4. 2009-07-23. PMID:19374457. |
adolescent depression can be effectively treated with selective serotonin reuptake inhibitors (ssris), such as fluoxetine, or with specific forms of psychotherapy, such as cognitive-behavioural therapy (cbt) and interpersonal therapy. |
2009-07-23 |
2023-08-12 |
Not clear |
| Antonino Santangelo, Manuela Testaì, Patrizia Barbagallo, Cristiano Crisafulli, Sebastiano Grasso, Sara Manuele, Giuliana Muscarà, Maurizio Rizzotto, Marcello Tomarchio, Domenico Mauger. Use of specific serotonin reuptake inhibitors (SSRIs) (Sertraline or Citalopram) in the treatment of depression reduces the cardiovascular risk in the elderly: evidence from a Sicilian population >80 years recovered in the assisted sanitary residences (RSA). Archives of gerontology and geriatrics. vol 48. issue 3. 2009-07-22. PMID:18440657. |
use of specific serotonin reuptake inhibitors (ssris) (sertraline or citalopram) in the treatment of depression reduces the cardiovascular risk in the elderly: evidence from a sicilian population >80 years recovered in the assisted sanitary residences (rsa). |
2009-07-22 |
2023-08-12 |
Not clear |
| Kerang Zhang, Qi Xu, Yong Xu, Hong Yang, Jinxiu Luo, Yan Sun, Ning Sun, Shan Wang, Yan She. The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population. Journal of affective disorders. vol 114. issue 1-3. 2009-07-22. PMID:18848359. |
serotonin transporter (5-htt) and 5-ht receptor (5-htr) involved in the neurotransmission of 5-ht may play an important role in the development of major depression disorder (mdd). |
2009-07-22 |
2023-08-12 |
Not clear |
| Esther Berrocoso, Pilar Sánchez-Blázquez, Javier Garzón, Juan A Mic. Opiates as antidepressants. Current pharmaceutical design. vol 15. issue 14. 2009-07-20. PMID:19442177. |
in fact, current pharmacological treatment for depression is based on the use of drugs that act mainly by enhancing brain serotonin and noradrenaline neurotransmission by the blockade of the active reuptake mechanism for these neurotransmitters. |
2009-07-20 |
2023-08-12 |
Not clear |
| A Abbas Asghar-Ali, U K Brau. Depression in geriatric patients. Minerva medica. vol 100. issue 1. 2009-07-16. PMID:19277008. |
first-line pharmacological therapy of depression includes selective serotonin inhibitors (ssris), and serotonin-norepinephrine reuptake inhibitors (snris). |
2009-07-16 |
2023-08-12 |
Not clear |
| Kuan-Pin S. Biological mechanism of antidepressant effect of omega-3 fatty acids: how does fish oil act as a 'mind-body interface'? Neuro-Signals. vol 17. issue 2. 2009-07-15. PMID:19190401. |
the unsatisfactory results of monoamine-based antidepressant therapy and the high occurrence of somatic symptoms and physical illness in patients with depression imply that the serotonin hypothesis is insufficient to approach the aetiology of depression. |
2009-07-15 |
2023-08-12 |
Not clear |
| Kuan-Pin S. Biological mechanism of antidepressant effect of omega-3 fatty acids: how does fish oil act as a 'mind-body interface'? Neuro-Signals. vol 17. issue 2. 2009-07-15. PMID:19190401. |
docosahexaenoic acid deficiency is associated with dysfunctions of neuronal membrane stability and transmission of serotonin, norepinephrine and dopamine, which might connect to the aetiology of mood and cognitive dysfunction of depression. |
2009-07-15 |
2023-08-12 |
Not clear |
| David M Stresser, Andrew K Mason, Elke S Perloff, Thuy Ho, Charles L Crespi, Andre A Dandeneau, Ling Morgan, Shangara S Deha. Differential time- and NADPH-dependent inhibition of CYP2C19 by enantiomers of fluoxetine. Drug metabolism and disposition: the biological fate of chemicals. vol 37. issue 4. 2009-07-14. PMID:19144769. |
fluoxetine [+/--n-methyl-3-phenyl-3-[(alpha, alpha, (-trifluoro-p-tolyl)oxy]-propylamine)] a selective serotonin reuptake inhibitor, is widely used in treating depression and other serotonin-dependent disease conditions. |
2009-07-14 |
2023-08-12 |
human |
| A Newman-Tancredi, J-C Martel, M-B Assié, J Buritova, E Lauressergues, C Cosi, P Heusler, L Bruins Slot, F C Colpaert, B Vacher, D Cussa. Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist. British journal of pharmacology. vol 156. issue 2. 2009-07-14. PMID:19154445. |
activation of post-synaptic 5-ht(1a) receptors may provide enhanced therapy against depression. |
2009-07-14 |
2023-08-12 |
Not clear |
| Shripad B Deshpande, Amar N Maurya, Jitendra N Sing. 5-HT-induced depression of the spinal monosynaptic reflex potential utilizes different types of 5-HT receptors depending on Mg2+ availability. Pharmacological reports : PR. vol 61. issue 2. 2009-07-14. PMID:19443937. |
5-ht-induced depression of the spinal monosynaptic reflex potential utilizes different types of 5-ht receptors depending on mg2+ availability. |
2009-07-14 |
2023-08-12 |
rat |
| Shripad B Deshpande, Amar N Maurya, Jitendra N Sing. 5-HT-induced depression of the spinal monosynaptic reflex potential utilizes different types of 5-HT receptors depending on Mg2+ availability. Pharmacological reports : PR. vol 61. issue 2. 2009-07-14. PMID:19443937. |
receptor subtypes involved in the 5-hydroxytryptamine (5-ht)-induced depression of synaptic transmission in neonatal rat spinal cords in vitro were evaluated in the absence or presence of mg(2+) in the medium. |
2009-07-14 |
2023-08-12 |
rat |