| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert K McNamara, Jessica Able, Yanhong Liu, Ronald Jandacek, Therese Rider, Patrick Tso, Jack W Lipto. Omega-3 fatty acid deficiency during perinatal development increases serotonin turnover in the prefrontal cortex and decreases midbrain tryptophan hydroxylase-2 expression in adult female rats: dissociation from estrogenic effects. Journal of psychiatric research. vol 43. issue 6. 2009-05-13. PMID:18986658. |
a dysregulation in central serotonin neurotransmission and omega-3 fatty acid deficiency have been implicated in the pathophysiology of major depression. |
2009-05-13 |
2023-08-12 |
rat |
| Ya-jing Qin, Yuan-shan Zeng, Chun-chun Zhou, Yan Li, Zhi-qiang Zhon. [Effects of Rhodiola rosea on level of 5-hydroxytryptamine, cell proliferation and differentiation, and number of neuron in cerebral hippocampus of rats with depression induced by chronic mild stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 33. issue 23. 2009-05-13. PMID:19260327. |
[effects of rhodiola rosea on level of 5-hydroxytryptamine, cell proliferation and differentiation, and number of neuron in cerebral hippocampus of rats with depression induced by chronic mild stress]. |
2009-05-13 |
2023-08-12 |
rat |
| Ya-jing Qin, Yuan-shan Zeng, Chun-chun Zhou, Yan Li, Zhi-qiang Zhon. [Effects of Rhodiola rosea on level of 5-hydroxytryptamine, cell proliferation and differentiation, and number of neuron in cerebral hippocampus of rats with depression induced by chronic mild stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 33. issue 23. 2009-05-13. PMID:19260327. |
to explore the effects of rhodiola rosea on the level of 5-hydroxytryptamine (5-ht), cell proliferation and differentiation, and number of neuron in cerebral hippocampus of rats with depression induced by chronic mild stress. |
2009-05-13 |
2023-08-12 |
rat |
| S J Warden, E M Hane. Skeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: evidence from in vitro and animal-based studies. Journal of musculoskeletal & neuronal interactions. vol 8. issue 2. 2009-05-05. PMID:18622081. |
by antagonizing the 5-htt, selective serotonin reuptake inhibitors (ssris) potentiate 5-ht activity and effectively relieve the symptoms of depression. |
2009-05-05 |
2023-08-12 |
Not clear |
| Horst J Koch, Tim P Jürgen. Antidepressants in long-term migraine prevention. Drugs. vol 69. issue 1. 2009-04-30. PMID:19192933. |
pathophysiologically, multiple neurotransmitters have been attributed an important role in the aetiology of migraine (mainly serotonin and calcitonin gene-related peptide) and depression (among others, serotonin, dopamine and noradrenaline [norepinephrine]). |
2009-04-30 |
2023-08-12 |
Not clear |
| Teresa Biermann, Nikolaos Stilianakis, Stefan Bleich, Norbert Thürauf, Johannes Kornhuber, Udo Reulbac. The hypothesis of an impact of ozone on the occurrence of completed and attempted suicides. Medical hypotheses. vol 72. issue 3. 2009-04-28. PMID:19027246. |
biologically, ozone is able to influence the immune system, is a strong trigeminal irritant and might influence neurotransmitter systems such as serotonin, which are known to vary with season and play a major role in impulsivity, aggression, depression and thereby suicidality. |
2009-04-28 |
2023-08-12 |
human |
| Carmela Dell'aversano, Carmine Tomasetti, Felice Iasevoli, Andrea de Bartolomei. Antipsychotic and antidepressant co-treatment: effects on transcripts of inducible postsynaptic density genes possibly implicated in behavioural disorders. Brain research bulletin. vol 79. issue 2. 2009-04-28. PMID:19189858. |
selective serotonin reuptake inhibitors (ssris) and antipsychotics co-administration is a widely used strategy to treat both psychotic depression and depressive symptoms in schizophrenia. |
2009-04-28 |
2023-08-12 |
Not clear |
| Antoine Pelissol. [Depression and pain: prevalence and clinical implication]. Presse medicale (Paris, France : 1983). vol 38. issue 3. 2009-04-27. PMID:18977630. |
in line with monoaminergic hypotheses shown above, this is in favour of the use of these serotonin and norepinephrine reuptake inhibitors in depression with important physical pains, but this issue needs further confirmation studies. |
2009-04-27 |
2023-08-12 |
Not clear |
| Yan Chen, Jeff J Guo, Nick C Pate. Hemorrhagic stroke associated with antidepressant use in patients with depression: does degree of serotonin reuptake inhibition matter? Pharmacoepidemiology and drug safety. vol 18. issue 3. 2009-04-27. PMID:19115419. |
hemorrhagic stroke associated with antidepressant use in patients with depression: does degree of serotonin reuptake inhibition matter? |
2009-04-27 |
2023-08-12 |
Not clear |
| Yan Chen, Jeff J Guo, Nick C Pate. Hemorrhagic stroke associated with antidepressant use in patients with depression: does degree of serotonin reuptake inhibition matter? Pharmacoepidemiology and drug safety. vol 18. issue 3. 2009-04-27. PMID:19115419. |
this study aimed to determine whether the degree of serotonin (5-ht) reuptake inhibition affects risk of hemorrhagic stroke associated with antidepressant use in patients with depression. |
2009-04-27 |
2023-08-12 |
Not clear |
| David G S Perahia, Deborah Quail, Durisala Desaiah, Angel L Montejo, Alan F Schatzber. Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression. Journal of psychiatric research. vol 43. issue 5. 2009-04-24. PMID:18707693. |
switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression. |
2009-04-24 |
2023-08-12 |
Not clear |
| Elizabeth A Young, Susan G Kornstein, Sheila M Marcus, Anne T Harvey, Diane Warden, Stephen R Wisniewski, G K Balasubramani, Maurizio Fava, Madhukar H Trivedi, A John Rus. Sex differences in response to citalopram: a STAR*D report. Journal of psychiatric research. vol 43. issue 5. 2009-04-24. PMID:18752809. |
controversy exists as to whether women with depression respond better to selective serotonin reuptake inhibitors (ssris) than men. |
2009-04-24 |
2023-08-12 |
Not clear |
| Paula L Hensley, Carol K Slonimski, E H Uhlenhuth, Paula J Clayto. Escitalopram: an open-label study of bereavement-related depression and grief. Journal of affective disorders. vol 113. issue 1-2. 2009-04-21. PMID:18597854. |
several studies of psychotropic medications have demonstrated improvement in depression ratings, but little data exists for selective serotonin reuptake inhibitor treatment in bereavement-related depression. |
2009-04-21 |
2023-08-12 |
Not clear |
| Masahide Yoshida, Yuki Takayanagi, Kiyoshi Inoue, Tadashi Kimura, Larry J Young, Tatsushi Onaka, Katsuhiko Nishimor. Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 7. 2009-04-16. PMID:19228979. |
these results also have important implications for psychiatric disorders such as autism and depression in which both the oxytocin and serotonin systems have been implicated. |
2009-04-16 |
2023-08-12 |
mouse |
| Francesco Benedetti, Barbara Barbini, Alessandro Bernasconi, Mara Cigala Fulgosi, Cristina Colombo, Sara Dallaspezia, Chiara Gavinelli, Elena Marino, Adele Pirovano, Daniele Radaelli, Enrico Smerald. Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 8. 2009-04-15. PMID:18801406. |
serotonin 5-ht2a receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. |
2009-04-15 |
2023-08-12 |
Not clear |
| Sarah Durkin, Alison Prendergast, Andrew Harki. Reduced efficacy of fluoxetine following MDMA ("Ecstasy")-induced serotonin loss in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 8. 2009-04-15. PMID:18824064. |
such loss may be problematic considering that psychiatric disorders such as depression and anxiety and responses to first line treatments for these disorders are associated with 5-ht. |
2009-04-15 |
2023-08-12 |
rat |
| Sarah Durkin, Alison Prendergast, Andrew Harki. Reduced efficacy of fluoxetine following MDMA ("Ecstasy")-induced serotonin loss in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 8. 2009-04-15. PMID:18824064. |
these results have potential clinical relevance, suggesting that 5-ht re-uptake inhibitors such as fluoxetine may be less effective at treating depression in chronic abusers of mdma. |
2009-04-15 |
2023-08-12 |
rat |
| J Contreras, L Hare, B Camarena, D Glahn, A Dassori, R Medina, S Contreras, M Ramirez, R Armas, R Munoz, R Mendoza, H Raventos, A Ontiveros, H Nicolini, R Palmer, M Escamill. The serotonin transporter 5-HTTPR polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders. Acta psychiatrica Scandinavica. vol 119. issue 2. 2009-04-15. PMID:19016667. |
the serotonin transporter 5-httpr polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders. |
2009-04-15 |
2023-08-12 |
Not clear |
| J Contreras, L Hare, B Camarena, D Glahn, A Dassori, R Medina, S Contreras, M Ramirez, R Armas, R Munoz, R Mendoza, H Raventos, A Ontiveros, H Nicolini, R Palmer, M Escamill. The serotonin transporter 5-HTTPR polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders. Acta psychiatrica Scandinavica. vol 119. issue 2. 2009-04-15. PMID:19016667. |
variation in the serotonin transporter gene (slc6a4) promoter region has been shown to influence depression in persons who have been exposed to a number of stressful life events. |
2009-04-15 |
2023-08-12 |
Not clear |
| Joël Bockaert, Sylvie Claeysen, Valérie Compan, Aline Dumui. 5-HT(4) receptors: history, molecular pharmacology and brain functions. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18603269. |
however, since 5-ht(4) receptors have recognized effects on memory, depression and feeding in animal models, there is still hope for a therapeutic destiny of this interesting target in brain disorders. |
2009-04-14 |
2023-08-12 |
Not clear |