| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cecilie L Licht, Anders B Marcussen, Gregers Wegener, David H Overstreet, Susana Aznar, Gitte M Knudse. The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476548. |
thus, the 5-ht(4) receptor binding was decreased in the flinders sensitive line depression model and in response to chronic paroxetine administration. |
2009-06-15 |
2023-08-12 |
rat |
| Z N Mannie, J Barnes, G C Bristow, C J Harmer, P J Cowe. Memory impairment in young women at increased risk of depression: influence of cortisol and 5-HTT genotype. Psychological medicine. vol 39. issue 5. 2009-06-11. PMID:18775088. |
the aim of the present study was to determine whether memory impairments were present in young women at increased familial risk of depression and whether memory performance was related either to cortisol secretion or to allelic variation in the promoter region of the serotonin transporter gene (5-htt). |
2009-06-11 |
2023-08-12 |
Not clear |
| Leea H Muhonen, Jouko Lönnqvist, Jari Lahti, Hannu Alh. Age at onset of first depressive episode as a predictor for escitalopram treatment of major depression comorbid with alcohol dependence. Psychiatry research. vol 167. issue 1-2. 2009-06-10. PMID:19346004. |
the aim of this study was to determine predictors of the response to escitalopram, a selective serotonin re-uptake inhibitor antidepressant and memantine, a non-competitive glutamate nmda receptor blocker, for the treatment of major depression comorbid with alcohol dependence. |
2009-06-10 |
2023-08-12 |
Not clear |
| Joan Rosenbaum Asarnow, Graham Emslie, Greg Clarke, Karen Dineen Wagner, Anthony Spirito, Benedetto Vitiello, Satish Iyengar, Wael Shamseddeen, Louise Ritz, Boris Birmaher, Neal Ryan, Betsy Kennard, Taryn Mayes, Lynn DeBar, James McCracken, Michael Strober, Robert Suddath, Henrietta Leonard, Giovanna Porta, Martin Keller, David Bren. Treatment of selective serotonin reuptake inhibitor-resistant depression in adolescents: predictors and moderators of treatment response. Journal of the American Academy of Child and Adolescent Psychiatry. vol 48. issue 3. 2009-06-09. PMID:19182688. |
treatment of selective serotonin reuptake inhibitor-resistant depression in adolescents: predictors and moderators of treatment response. |
2009-06-09 |
2023-08-12 |
Not clear |
| Joan Rosenbaum Asarnow, Graham Emslie, Greg Clarke, Karen Dineen Wagner, Anthony Spirito, Benedetto Vitiello, Satish Iyengar, Wael Shamseddeen, Louise Ritz, Boris Birmaher, Neal Ryan, Betsy Kennard, Taryn Mayes, Lynn DeBar, James McCracken, Michael Strober, Robert Suddath, Henrietta Leonard, Giovanna Porta, Martin Keller, David Bren. Treatment of selective serotonin reuptake inhibitor-resistant depression in adolescents: predictors and moderators of treatment response. Journal of the American Academy of Child and Adolescent Psychiatry. vol 48. issue 3. 2009-06-09. PMID:19182688. |
to advance knowledge regarding strategies for treating selective serotonin reuptake inhibitor (ssri)-resistant depression in adolescents, we conducted a randomized controlled trial evaluating alternative treatment strategies. |
2009-06-09 |
2023-08-12 |
Not clear |
| Nadeeka N W Dissanayaka, Peter A Silburn, John D O'Sullivan, George D Mellic. Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 1. 2009-06-04. PMID:18973248. |
serotonin and dopamine transporter genes do not influence depression in parkinson's disease. |
2009-06-04 |
2023-08-12 |
Not clear |
| Nadeeka N W Dissanayaka, Peter A Silburn, John D O'Sullivan, George D Mellic. Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 1. 2009-06-04. PMID:18973248. |
altered levels of the neurotransmitters dopamine and serotonin are observed in both parkinson's disease (pd) and depression. |
2009-06-04 |
2023-08-12 |
Not clear |
| Nadeeka N W Dissanayaka, Peter A Silburn, John D O'Sullivan, George D Mellic. Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 1. 2009-06-04. PMID:18973248. |
therefore, the neurotransmitter transporter genes, slc6a3 (dopamine) and slc6a4 (serotonin) are candidates for depression in pd. |
2009-06-04 |
2023-08-12 |
Not clear |
| Nadeeka N W Dissanayaka, Peter A Silburn, John D O'Sullivan, George D Mellic. Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 1. 2009-06-04. PMID:18973248. |
no significant genotype or haplotype associations were observed suggesting that common genetic variables around the dopamine and serotonin transporter genes do not play a significant role in the etiology of depression in pd. |
2009-06-04 |
2023-08-12 |
Not clear |
| Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Paweł Kapelski, Maria Skibińska, Magdalena Kaczmarkiewicz-Fass, Joanna Hause. [Association between polymorphisms of ins/del in the 5-HTT gene and T102C in the 5HTR2A gene and the drug response for escitalopram and nortriptyline in depressed patients]. Psychiatria polska. vol 42. issue 6. 2009-06-04. PMID:19441667. |
the role of the serotonin receptor 5ht2a and serotonin transporter 5httlpr polymorphisms was suggested in the pathogenesis of depression and the therapeutic response to serotonergic drugs. |
2009-06-04 |
2023-08-12 |
Not clear |
| O Riccio, G Potter, C Walzer, P Vallet, G Szabó, L Vutskits, J Z Kiss, A G Daye. Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6. Molecular psychiatry. vol 14. issue 3. 2009-06-03. PMID:18663366. |
the discovery that a common polymorphism (5-httlpr, short variant) in the human serotonin transporter gene (slc6a4) can influence personality traits and increase the risk for depression in adulthood has led to the hypothesis that a relative increase in the extracellular levels of serotonin (5-ht) during development could be critical for the establishment of brain circuits. |
2009-06-03 |
2023-08-12 |
mouse |
| Laura Lambás-Señas, Ouissame Mnie-Filali, Véronique Certin, Céline Faure, Laetitia Lemoine, Luc Zimmer, Nasser Haddjer. Functional correlates for 5-HT(1A) receptors in maternally deprived rats displaying anxiety and depression-like behaviors. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19111592. |
because serotonin (5-ht) 5-ht(1a) receptors seem to play an important role in the pathophysiology of major depression and in the mechanism of action of antidepressants, we investigated if 5-ht(1a) receptor function is altered in deprived rats. |
2009-06-02 |
2023-08-12 |
rat |
| Kimberly K McClanaha. Depression in pregnant adolescents: considerations for treatment. Journal of pediatric and adolescent gynecology. vol 22. issue 1. 2009-06-01. PMID:19241624. |
treating depression in the pregnant adolescent is complex due to the concerns about the use of selective serotonin reuptake inhibitors (ssris) in any pregnant woman, the fact that only one ssri (fluoxetine) is fda-approved for depression in the pediatric population, the concern over the black box warning for antidepressants in the pediatric population, and the reality that untreated depression in pregnancy has been shown to be associated with poor outcomes for both mother and baby. |
2009-06-01 |
2023-08-12 |
Not clear |
| M R Lemk. [Antidepressant effects of dopamine agonists. Experimental and clinical findings]. Der Nervenarzt. vol 78. issue 1. 2009-05-29. PMID:17187269. |
results of preclinical and clinical studies implicate that, in addition to serotonin and norepinephrin, dopaminergic mechanisms play a role in the pathogenesis and treatment of depression. |
2009-05-29 |
2023-08-12 |
Not clear |
| Troy Voelker, Haiji Xia, Keith Fandrick, Robert Johnson, Aaron Janowsky, John R Cashma. 2,5-Disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors. Bioorganic & medicinal chemistry. vol 17. issue 5. 2009-05-29. PMID:19201198. |
enhancement of 5-hydroxytryptamine (5-ht, serotonin) neurotransmission is a viable means of treating depression. |
2009-05-29 |
2023-08-12 |
mouse |
| Ting-Ting Chang, Chhian-Hui Lêng, Jo Yung-Wei Wu, Sheng-Yu Lee, Yu-Shan Wang, Yi-Chyan Chen, Ru-Band L. Lower side effects of milnacipran than paroxetine in the treatment of major depression disorder among Han Chinese in Taiwan. The Chinese journal of physiology. vol 51. issue 6. 2009-05-29. PMID:19280883. |
the present study compares milnacipran with paroxetine, a selective serotonin reuptake inhibitor (ssri) and which has been used clinically for years to evaluate the efficacy, patient tolerance, and side effects in the treatment of major depression. |
2009-05-29 |
2023-08-12 |
human |
| Zheng-xin Chen, He-qiu Wang, Wei-dong Ji. [Selective serotonin reuptake inhibitor is more likely to induce sexual dysfunction than mirtazapine in treating depression]. Zhonghua nan ke xue = National journal of andrology. vol 14. issue 10. 2009-05-28. PMID:19157098. |
[selective serotonin reuptake inhibitor is more likely to induce sexual dysfunction than mirtazapine in treating depression]. |
2009-05-28 |
2023-08-12 |
Not clear |
| A Testu. [Depression and myocardial infaction]. Revue medicale suisse. vol 5. issue 193. 2009-05-28. PMID:19374048. |
treatment of depression is not associated with better cardiovascular outcome, but selective serotonin reuptake inhibitors have been shown safe and efficient among patients with coronary heart disease. |
2009-05-28 |
2023-08-12 |
Not clear |
| R C Shelton, E Sanders-Bush, D H Manier, D A Lewi. Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19111907. |
elevated 5-ht 2a receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase a. |
2009-05-20 |
2023-08-12 |
human |
| D A Mrazek, A J Rush, J M Biernacka, D J O'Kane, J M Cunningham, E D Wieben, D J Schaid, M S Drews, V L Courson, K A Snyder, J L Black, R M Weinshilbou. SLC6A4 variation and citalopram response. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 3. 2009-05-19. PMID:18618621. |
the influence of genetic variations in slc6a4 (serotonin transporter gene) on citalopram treatment of depression using the sequenced treatment to relieve depression (star*d) sample was assessed. |
2009-05-19 |
2023-08-12 |
human |