| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ichiro M Omori, Norio Watanabe, Atsuo Nakagawa, Andrea Cipriani, Corrado Barbui, Hugh McGuire, Rachel Churchill, Toshi A Furukaw. Fluvoxamine versus other anti-depressive agents for depression. The Cochrane database of systematic reviews. issue 3. 2010-04-26. PMID:20238342. |
fluvoxamine, one of the oldest selective serotonin reuptake inhibitors (ssris), is prescribed to patients with major depression in many countries. |
2010-04-26 |
2023-08-12 |
Not clear |
| Kai Yu, Chen-Li Qiu, Gui-Bo Yang, Chun-Miao Zong, Hui Xing, Yiming Shao, Qiang Wei, Chuan Qi. Alteration of serotonin transporter messenger RNA level in the peripheral blood mononuclear cells from simian/human immunodeficiency virus infected Chinese rhesus macaques (Macaca mulatta). Brain, behavior, and immunity. vol 24. issue 2. 2010-04-23. PMID:19854262. |
these data indicated that, in addition to previously observed abnormality in serotonin metabolism, sert expression might be affected in hiv/aids, which might be associated with depression and other psychiatric disorders in hiv/aids. |
2010-04-23 |
2023-08-12 |
monkey |
| Elizabeth M Haney, Stuart J Warden, M Michael Bliziote. Effects of selective serotonin reuptake inhibitors on bone health in adults: time for recommendations about screening, prevention and management? Bone. vol 46. issue 1. 2010-04-21. PMID:19664737. |
serotonin is involved in the pathophysiology of depression, and therefore studies of depression and antidepressant treatments (as modulators of the serotonin system) are relevant with regard to bone outcomes. |
2010-04-21 |
2023-08-12 |
Not clear |
| Anett Mueller, Burkhard Brocke, Eva Fries, Klaus-Peter Lesch, Clemens Kirschbau. The role of the serotonin transporter polymorphism for the endocrine stress response in newborns. Psychoneuroendocrinology. vol 35. issue 2. 2010-04-16. PMID:19647944. |
a functional polymorphism in the 5'flanking region of the serotonin transporter gene (17q11.2, 5-httlpr) alters the transcription of the 5-ht transporter gene and seems to be associated with depression and anxiety-related personality traits in humans. |
2010-04-16 |
2023-08-12 |
Not clear |
| R Ghanbari, M El Mansari, P Blie. Electrophysiological effects of the co-administration of escitalopram and bupropion on rat serotonin and norepinephrine neurons. Journal of psychopharmacology (Oxford, England). vol 24. issue 1. 2010-04-15. PMID:18719044. |
clinical studies indicate that addition of bupropion to selective serotonin (5-ht) reuptake inhibitors (ssris) provides incremental benefit over ssri monotherapy in depression. |
2010-04-15 |
2023-08-12 |
rat |
| Constance Hammen, Patricia A Brennan, Danielle Keenan-Miller, Nicholas A Hazel, Jake M Najma. Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth. Journal of child psychology and psychiatry, and allied disciplines. vol 51. issue 2. 2010-04-15. PMID:19811586. |
chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth. |
2010-04-15 |
2023-08-12 |
Not clear |
| Constance Hammen, Patricia A Brennan, Danielle Keenan-Miller, Nicholas A Hazel, Jake M Najma. Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth. Journal of child psychology and psychiatry, and allied disciplines. vol 51. issue 2. 2010-04-15. PMID:19811586. |
many recent studies of serotonin transporter gene by environment effects predicting depression have used stress assessments with undefined or poor psychometric methods, possibly contributing to wide variation in findings. |
2010-04-15 |
2023-08-12 |
Not clear |
| Roberto Viviani, Eun-Jin Sim, Hanna Lo, Petra Beschoner, Nadine Osterfeld, Christiane Maier, Angela Seeringer, Ana Leonor Godoy, Araceli Rosa, David Comas, Julia Kirchheine. Baseline brain perfusion and the serotonin transporter promoter polymorphism. Biological psychiatry. vol 67. issue 4. 2010-04-14. PMID:19878929. |
the serotonin transporter length repeat polymorphism (5-httlpr) in the promoter region of the serotonin transporter gene (slc6a4) has been associated in healthy subjects with changes in basal perfusion levels in the limbic system and ventral prefrontal areas, regions involved in the pathophysiology of depression and anxiety, suggesting the existence of a neurobiological trait predisposing to these disorders. |
2010-04-14 |
2023-08-12 |
human |
| Silke Heinisch, Lynn G Kirb. SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Neuropharmacology. vol 58. issue 2. 2010-04-13. PMID:19755127. |
the serotonin (5-hydroxytryptamine; 5-ht) system has a well-characterized role in depression. |
2010-04-13 |
2023-08-12 |
rat |
| Silke Heinisch, Lynn G Kirb. SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Neuropharmacology. vol 58. issue 2. 2010-04-13. PMID:19755127. |
future therapies targeting cxcl12 and other chemokines may treat serotonin related mood disorders, particularly depression experienced by immune-compromised individuals. |
2010-04-13 |
2023-08-12 |
rat |
| Dima A Hammoud, Christopher J Endres, Edward Hammond, Ovsev Uzuner, Amanda Brown, Avindra Nath, Adam I Kaplin, Martin G Pompe. Imaging serotonergic transmission with [11C]DASB-PET in depressed and non-depressed patients infected with HIV. NeuroImage. vol 49. issue 3. 2010-04-13. PMID:19853044. |
the goal of this study was to evaluate the involvement of serotonergic transmission in hiv-associated depression using [(11)c]dasb, a serotonin transporter (5-htt)-specific radiopharmaceutical for positron emission tomography (pet). |
2010-04-13 |
2023-08-12 |
Not clear |
| Ivan Skelin, Hiroki Sato, Tomislav Kovacević, Mirko Diksi. Chronic therapy with citalopram decreases regional cerebral glucose utilization in OBX, and not sham-operated, rats: an autoradiographic study. Psychopharmacology. vol 207. issue 2. 2010-04-08. PMID:19760282. |
chronic treatment with the selective serotonin reuptake inhibitor, citalopram, normalizes several behavioral and neurochemical abnormalities in the olfactory bulbectomized (obx) rat model of depression. |
2010-04-08 |
2023-08-12 |
rat |
| Judith R Homberg, Dirk Schubert, Patricia Gaspa. New perspectives on the neurodevelopmental effects of SSRIs. Trends in pharmacological sciences. vol 31. issue 2. 2010-04-07. PMID:19963284. |
selective serotonin reuptake inhibitors (ssris) are widely prescribed for the treatment of depression and anxiety-related disorders. |
2010-04-07 |
2023-08-12 |
mouse |
| Steven Reid, Corrado Barbu. Long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants. BMJ (Clinical research ed.). vol 340. 2010-04-05. PMID:20348175. |
long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants. |
2010-04-05 |
2023-08-12 |
Not clear |
| Ivan Skelin, Hiroki Sato, Mirko Diksi. Acute challenge with d-fenfluramine decreases regional cerebral glucose utilization in Sham, but not in OBX, rats: an autoradiographic study. Brain research. vol 1310. 2010-03-30. PMID:19912994. |
d-fenfluramine is a 5-ht releasing drug, frequently used in the study of the responsivity of the 5-ht system in subjects with psychiatric disorders, including depression. |
2010-03-30 |
2023-08-12 |
human |
| b' Marta Kubera, Michael Maes, Bogus\\xc5\\x82awa Budziszewska, Agnieszka Basta-Kaim, Monika Le\\xc5\\x9bkiewicz, Beata Grygier, Zofia Rog\\xc3\\xb3z, W\\xc5\\x82adys\\xc5\\x82aw Laso\\xc5\\x8. Inhibitory effects of amantadine on the production of pro-inflammatory cytokines by stimulated in vitro human blood. Pharmacological reports : PR. vol 61. issue 6. 2010-03-30. PMID:20081246.' |
the above data provide additional rationale for the treatment of patients suffering from depression with a combination of ama and a selective serotonin reuptake inhibitor. |
2010-03-30 |
2023-08-12 |
human |
| Jonathan W Stewart, Patrick J McGrath, Maurizio Fava, Stephen R Wisniewski, Sidney Zisook, Ian Cook, Andrew A Nierenberg, Madhukar H Trivedi, G K Balasubramani, Diane Warden, Ira Lesser, A John Rus. Do atypical features affect outcome in depressed outpatients treated with citalopram? The international journal of neuropsychopharmacology. vol 13. issue 1. 2010-03-23. PMID:19341509. |
the efficacy and tolerability of selective serotonin reuptake inhibitors (ssris) have not been fully evaluated in depression with atypical features. |
2010-03-23 |
2023-08-12 |
human |
| Anneke D M Haddad, J Mark G Williams, Sarah F B McTavish, Catherine J Harme. Low-dose tryptophan depletion in recovered depressed women induces impairments in autobiographical memory specificity. Psychopharmacology. vol 207. issue 3. 2010-03-23. PMID:19813003. |
serotonin is implicated in both depression and long-term memory; therefore, temporary lowering of brain serotonin function via acute tryptophan depletion (atd) offers a means of studying the role of serotonin in autobiographical memory specificity. |
2010-03-23 |
2023-08-12 |
Not clear |
| Jesse W Richardson-Jones, Caryne P Craige, Bruno P Guiard, Alisson Stephen, Kayla L Metzger, Hank F Kung, Alain M Gardier, Alex Dranovsky, Denis J David, Sheryl G Beck, René Hen, E David Leonard. 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron. vol 65. issue 1. 2010-03-23. PMID:20152112. |
human studies implicate a polymorphism in the promoter of the serotonin-1a (5-ht(1a)) receptor gene in increased susceptibility to depression and decreased treatment response. |
2010-03-23 |
2023-08-12 |
mouse |
| Mani Kandasamy, Krishnanand Tripathy, Sandhya Ravi, Narendra Kamath, Balakrishna Pai, Nuggehally R Srinivas, Fjalar Kristjansson, Saral Thanga. Unsuspected poor metabolizer phenotypes of fluoxetine in bioavailability/bioequivalence studies from an indian population perspective. Retrospective pharmacokinetic data evaluation. Arzneimittel-Forschung. vol 60. issue 1. 2010-03-22. PMID:20184222. |
fluoxetine, belonging to the class of selective serotonin uptake inhibitors, has been extensively used for the treatment of depression and other psychiatry related disorders. |
2010-03-22 |
2023-08-12 |
Not clear |