Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
George B Richerson, Gordon F Buchana. The serotonin axis: Shared mechanisms in seizures, depression, and SUDEP. Epilepsia. vol 52 Suppl 1. 2011-01-31. PMID:21214537. |
herein we discuss the possibility that underlying pathology in the serotonin (5-ht) system of patients with epilepsy lowers the threshold for seizures, while also increasing the risk of depression and sudden death. |
2011-01-31 |
2023-08-12 |
Not clear |
George B Richerson, Gordon F Buchana. The serotonin axis: Shared mechanisms in seizures, depression, and SUDEP. Epilepsia. vol 52 Suppl 1. 2011-01-31. PMID:21214537. |
we propose that postictal dysfunction of 5-ht neurons causes depression of breathing and arousal in some epilepsy patients, and this can lead to sudden unexpected death in epilepsy (sudep). |
2011-01-31 |
2023-08-12 |
Not clear |
Javier Contreras, Sandra Hernández, Paulina Quezada, Albana Dassori, Consuelo Walss-Bass, Michael Escamilla, Henriette Ravento. Association of serotonin transporter promoter gene polymorphism (5-HTTLPR) with depression in Costa Rican schizophrenic patients. Journal of neurogenetics. vol 24. issue 2. 2011-01-27. PMID:20397838. |
association of serotonin transporter promoter gene polymorphism (5-httlpr) with depression in costa rican schizophrenic patients. |
2011-01-27 |
2023-08-12 |
human |
Javier Contreras, Sandra Hernández, Paulina Quezada, Albana Dassori, Consuelo Walss-Bass, Michael Escamilla, Henriette Ravento. Association of serotonin transporter promoter gene polymorphism (5-HTTLPR) with depression in Costa Rican schizophrenic patients. Journal of neurogenetics. vol 24. issue 2. 2011-01-27. PMID:20397838. |
the short allele of serotonin transporter gene has been associated with depression and suicidality in individuals who suffered negative life events and with depression in individuals with chronic psychosis.. |
2011-01-27 |
2023-08-12 |
human |
Javier Contreras, Sandra Hernández, Paulina Quezada, Albana Dassori, Consuelo Walss-Bass, Michael Escamilla, Henriette Ravento. Association of serotonin transporter promoter gene polymorphism (5-HTTLPR) with depression in Costa Rican schizophrenic patients. Journal of neurogenetics. vol 24. issue 2. 2011-01-27. PMID:20397838. |
the authors hypothesized that subjects with at least one copy of the serotonin transporter promoter gene polymorphism (5-httlpr) "s" allele would have a greater history of lifetime depression and suicidability rate than those who had an "l/l" genotype. |
2011-01-27 |
2023-08-12 |
human |
Salih Saygin Eker, Cengiz Akkaya, Canan Ersoy, Asli Sarandol, Selcuk Kirl. Reversible escitalopram-induced hypothyroidism. General hospital psychiatry. vol 32. issue 5. 2011-01-21. PMID:20851281. |
apart from the well-known relationship between depression and hypothalamic-pituitary-thyroid (hpt) axis, and the impact of selective serotonin reuptake inhibitors (ssris) on thyroid indices, hypothyroidism is a very rare adverse effect of ssri treatment. |
2011-01-21 |
2023-08-12 |
Not clear |
Matthis Wankerl, Stefan Wüst, Christian Ott. Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression? Current opinion in psychiatry. vol 23. issue 6. 2011-01-21. PMID:20881788. |
current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-httlpr) modulate the association between stress and depression? |
2011-01-21 |
2023-08-12 |
human |
Matthis Wankerl, Stefan Wüst, Christian Ott. Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression? Current opinion in psychiatry. vol 23. issue 6. 2011-01-21. PMID:20881788. |
human observational studies have shown that, in interaction with life stress, the short or s-allele of the serotonin transporter gene-linked polymorphic region (5-httlpr) is associated with an enhanced risk for depression. |
2011-01-21 |
2023-08-12 |
human |
Itai Bab, Raz Yirmiy. Depression, selective serotonin reuptake inhibitors, and osteoporosis. Current osteoporosis reports. vol 8. issue 4. 2011-01-20. PMID:20809204. |
depression and bone antianabolic sympathetic tone are alleviated by increasing central serotonin (5-hydroxytryptamine, 5-ht) levels. |
2011-01-20 |
2023-08-12 |
mouse |
A G Franke, K Lie. [Pharmacological neuroenhancement and brain doping : Chances and risks]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. vol 53. issue 8. 2011-01-14. PMID:20700786. |
this subcategory includes psychostimulants (e.g., amphetamines, methylphenidate), modafinil, antidementia drugs (acetylcholine-esterase inhibitors, memantine), and antidepressants (selective serotonin reuptake inhibitors) which are being prescribed for the treatment of adhd (attention deficit/hyperactivity disorder), alzheimer's disease, and depression. |
2011-01-14 |
2023-08-12 |
human |
Anna Wesołowsk. Potential role of the 5-HT6 receptor in depression and anxiety: an overview of preclinical data. Pharmacological reports : PR. vol 62. issue 4. 2011-01-12. PMID:20884998. |
evidence indicates that both 5-ht(6) agonists and antagonists may evoke identical responses in animal models of depression and anxiety; however, the possible mechanisms of these effects seem to be diverse and are not clearly understood. |
2011-01-12 |
2023-08-12 |
Not clear |
Matthis Wankerl, Birgit-Christiane Zyriax, Brigitta Bondy, Kim Hinkelmann, Eberhard Windler, Christian Ott. Serotonin transporter gene-linked polymorphic region (5-HTTLPR) and diurnal cortisol: A sex by genotype interaction. Biological psychology. vol 85. issue 2. 2011-01-11. PMID:20637828. |
in interaction with stressful life events, the serotonin transporter gene-linked polymorphic region (5-httlpr) is associated with depression. |
2011-01-11 |
2023-08-12 |
Not clear |
Tami Benton, Kevin Lynch, Benoit Dubé, David R Gettes, Nancy B Tustin, Jian Ping Lai, David S Metzger, Joshua Blume, Steven D Douglas, Dwight L Evan. Selective serotonin reuptake inhibitor suppression of HIV infectivity and replication. Psychosomatic medicine. vol 72. issue 9. 2011-01-11. PMID:20947783. |
to test the hypothesis that the selective serotonin reuptake inhibitor (ssri) citalopram would down-regulate human immunodeficiency virus (hiv) infectivity and that the greatest effects would be seen in people with depression. |
2011-01-11 |
2023-08-12 |
human |
Tami Benton, Kevin Lynch, Benoit Dubé, David R Gettes, Nancy B Tustin, Jian Ping Lai, David S Metzger, Joshua Blume, Steven D Douglas, Dwight L Evan. Selective serotonin reuptake inhibitor suppression of HIV infectivity and replication. Psychosomatic medicine. vol 72. issue 9. 2011-01-11. PMID:20947783. |
serotonin (5-ht) neurotransmission has been implicated in the pathobiology of depression, and pharmacologic therapies for depression target this system. |
2011-01-11 |
2023-08-12 |
human |
Christopher C Conway, Constance Hammen, Patricia A Brennan, Penelope A Lind, Jake M Najma. Interaction of chronic stress with serotonin transporter and catechol-O-methyltransferase polymorphisms in predicting youth depression. Depression and anxiety. vol 27. issue 8. 2010-12-28. PMID:20577990. |
interaction of chronic stress with serotonin transporter and catechol-o-methyltransferase polymorphisms in predicting youth depression. |
2010-12-28 |
2023-08-12 |
Not clear |
Christopher C Conway, Constance Hammen, Patricia A Brennan, Penelope A Lind, Jake M Najma. Interaction of chronic stress with serotonin transporter and catechol-O-methyltransferase polymorphisms in predicting youth depression. Depression and anxiety. vol 27. issue 8. 2010-12-28. PMID:20577990. |
investigations of gene-environment interaction (gxe) in depression have implicated a polymorphism in the promoter region of the serotonin transporter gene (5-httlpr) as a moderator of the stress-depression relationship. |
2010-12-28 |
2023-08-12 |
Not clear |
N Antypa, A J W Van der Doe. Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression. Genes, brain, and behavior. vol 9. issue 6. 2010-12-27. PMID:20455953. |
serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression. |
2010-12-27 |
2023-08-12 |
human |
N Antypa, A J W Van der Doe. Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression. Genes, brain, and behavior. vol 9. issue 6. 2010-12-27. PMID:20455953. |
meta-analyses evaluating the association between the serotonin transporter polymorphism (5-httlpr) with neuroticism and depression diagnosis as phenotypes have been inconclusive. |
2010-12-27 |
2023-08-12 |
human |
Michel Hamo. [Serotonin: a player in both depression and bone remodeling]. Medecine sciences : M/S. vol 26. issue 8-9. 2010-12-22. PMID:20819694. |
[serotonin: a player in both depression and bone remodeling]. |
2010-12-22 |
2023-08-12 |
Not clear |
A V Kulikov, V S Naumenko, A S Tsybko, N A Siniakova, D V Bazovkina, N K Popov. [The role of the glycoprotein gp130 in serotonin mediator system in mouse brain]. Molekuliarnaia biologiia. vol 44. issue 5. 2010-12-17. PMID:21090245. |
il-6 and brain neurotransmitter serotonin are involved in the mechanism of depression. |
2010-12-17 |
2023-08-12 |
mouse |