| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Catena-Dell'Osso, C Bellantuono, G Consoli, S Baroni, F Rotella, D Marazzit. Inflammatory and neurodegenerative pathways in depression: a new avenue for antidepressant development? Current medicinal chemistry. vol 18. issue 2. 2011-05-03. PMID:21110802. |
according to the cytokine hypothesis, depression would be due to a stress-related increased production of pro-inflammatory cytokines that, in turn, would lead to increased oxidative and nitrosative brain damage and to indoleamine 2,3 dioxygenase (ido) induction, with production of tryptophan (trp) catabolites along the ido pathway (trycats) and consequent reduced availability of trp and serotonin (5-ht). |
2011-05-03 |
2023-08-12 |
Not clear |
| Frances L Lynch, John F Dickerson, Greg Clarke, Benedetto Vitiello, Giovanna Porta, Karen D Wagner, Graham Emslie, Joan Rosenbaum Asarnow, Martin B Keller, Boris Birmaher, Neal D Ryan, Betsy Kennard, Taryn Mayes, Lynn DeBar, James T McCracken, Michael Strober, Robert L Suddath, Anthony Spirito, Matthew Onorato, Jamie Zelazny, Satish Iyengar, David Bren. Incremental cost-effectiveness of combined therapy vs medication only for youth with selective serotonin reuptake inhibitor-resistant depression: treatment of SSRI-resistant depression in adolescents trial findings. Archives of general psychiatry. vol 68. issue 3. 2011-05-03. PMID:21383263. |
incremental cost-effectiveness of combined therapy vs medication only for youth with selective serotonin reuptake inhibitor-resistant depression: treatment of ssri-resistant depression in adolescents trial findings. |
2011-05-03 |
2023-08-12 |
Not clear |
| Frances L Lynch, John F Dickerson, Greg Clarke, Benedetto Vitiello, Giovanna Porta, Karen D Wagner, Graham Emslie, Joan Rosenbaum Asarnow, Martin B Keller, Boris Birmaher, Neal D Ryan, Betsy Kennard, Taryn Mayes, Lynn DeBar, James T McCracken, Michael Strober, Robert L Suddath, Anthony Spirito, Matthew Onorato, Jamie Zelazny, Satish Iyengar, David Bren. Incremental cost-effectiveness of combined therapy vs medication only for youth with selective serotonin reuptake inhibitor-resistant depression: treatment of SSRI-resistant depression in adolescents trial findings. Archives of general psychiatry. vol 68. issue 3. 2011-05-03. PMID:21383263. |
many youth with depression do not respond to initial treatment with selective serotonin reuptake inhibitors (ssris), and this is associated with higher costs. |
2011-05-03 |
2023-08-12 |
Not clear |
| Yukihiro Ohn. Therapeutic role of 5-HT1A receptors in the treatment of schizophrenia and Parkinson's disease. CNS neuroscience & therapeutics. vol 17. issue 1. 2011-05-02. PMID:21091640. |
in the treatment of patients with parkinson's disease, 5-ht(1a) agonists are expected to improve not only affective symptoms (e.g., anxiety and depression), but also the core parkinsonian symptoms as well as antiparkinsonian agents-induced side effects (e.g., l-dopa-induced dyskinesia). |
2011-05-02 |
2023-08-12 |
Not clear |
| Philippe Courte. Suicidality: risk factors and the effects of antidepressants. The example of parallel reduction of suicidality and other depressive symptoms during treatment with the SNRI, milnacipran. Neuropsychiatric disease and treatment. vol 6. 2011-04-28. PMID:20856596. |
a recent study has determined the effects of 6 weeks of antidepressant treatment with the serotonin and norepinephrine reuptake inhibitor, milnacipran, on suicidality in a cohort of 30 patients with mild to moderate depression. |
2011-04-28 |
2023-08-12 |
Not clear |
| Siegfried Kasper, Gerald Pai. Milnacipran: a unique antidepressant? Neuropsychiatric disease and treatment. vol 6. 2011-04-28. PMID:20856597. |
increasing evidence of the importance of norepinephrine in the etiology of depression has led to the development of a new generation of antidepressants, the serotonin and norepinephrine reuptake inhibitors (snris). |
2011-04-28 |
2023-08-12 |
Not clear |
| Rachel H Jacobs, Daniel S Pine, Michael E Schoeny, David B Henry, Jackie K Gollan, Gregory Moy, Edwin H Cook, Lauren S Wakschla. Maternal depressive history, teen 5HTTLPR genotype, and the processing of emotional faces: Exploring mechanisms of risk. Behaviour research and therapy. vol 49. issue 1. 2011-04-28. PMID:21092937. |
variations in the serotonin transporter gene (5httlpr) and biased processing of face-emotion displays both have been implicated in the transmission of depression risk, but little is known about developmental influences on these relationships. |
2011-04-28 |
2023-08-12 |
Not clear |
| Heidemarie Abrahamian, Peter Hofmann, Rudolf Prager, Hermann Topla. Diabetes mellitus and co-morbid depression: treatment with milnacipran results in significant improvement of both diseases (results from the Austrian MDDM study group). Neuropsychiatric disease and treatment. vol 5. 2011-04-26. PMID:19557120. |
we evaluated the feasibility of a two question screen for co-morbid depression in diabetic patients and studied the effect of the serotonin norepinephrine reuptake inhibitor antidepressant, milnacipran, on metabolic and psychological parameters in 64 type 2 diabetic patients with co-morbid depression. |
2011-04-26 |
2023-08-12 |
Not clear |
| Rena Cooper-Kazaz, Amihai Rigbi, Bernard Lere. Targeting remission by 8 weeks: when should supplementation be considered in patients with major depression treated with a specific serotonin reuptake inhibitor? Comprehensive psychiatry. vol 52. issue 1. 2011-04-25. PMID:21220060. |
targeting remission by 8 weeks: when should supplementation be considered in patients with major depression treated with a specific serotonin reuptake inhibitor? |
2011-04-25 |
2023-08-12 |
Not clear |
| Gwenn S Smith, Clifford I Workman, Elisse Kramer, Carol R Hermann, Rachel Ginsberg, Yilong Ma, Vijay Dhawan, Thomas Chaly, David Eidelber. The relationship between the acute cerebral metabolic response to citalopram and chronic citalopram treatment outcome. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 19. issue 1. 2011-04-08. PMID:21218565. |
this study tested the hypothesis that lower baseline glucose metabolism and greater acute cerebral metabolic responses to a single, intravenous (iv) dose of the selective serotonin reuptake inhibitor (ssri) citalopram would be associated with greater improvement of depressive symptoms after 12 weeks of citalopram treatment in geriatric depression. |
2011-04-08 |
2023-08-12 |
Not clear |
| S Oestergaard, C Møldru. Anticipated outcomes from introduction of 5-HTTLPR genotyping for depressed patients: an expert Delphi analysis. Public health genomics. vol 13. issue 7-8. 2011-04-07. PMID:20606382. |
the aim of this study was to investigate experts' opinions regarding the extent to which the introduction of pretesting for polymorphism of serotonin transporter promoter region (5-httlpr) as a routine intervention in clinical practice would lead to better clinical outcomes for depression patients. |
2011-04-07 |
2023-08-12 |
Not clear |
| Woojae Myung, Shinn-Won Lim, Jinwoo Kim, Yujin Lee, Jihye Song, Ki-won Chang, Doh Kwan Ki. Serotonin transporter gene polymorphisms and chronic illness of depression. Journal of Korean medical science. vol 25. issue 12. 2011-04-07. PMID:21165304. |
serotonin transporter gene polymorphisms and chronic illness of depression. |
2011-04-07 |
2023-08-12 |
human |
| Woojae Myung, Shinn-Won Lim, Jinwoo Kim, Yujin Lee, Jihye Song, Ki-won Chang, Doh Kwan Ki. Serotonin transporter gene polymorphisms and chronic illness of depression. Journal of Korean medical science. vol 25. issue 12. 2011-04-07. PMID:21165304. |
the serotonin transporter gene is one of the most studied genes for depression. |
2011-04-07 |
2023-08-12 |
human |
| Woojae Myung, Shinn-Won Lim, Jinwoo Kim, Yujin Lee, Jihye Song, Ki-won Chang, Doh Kwan Ki. Serotonin transporter gene polymorphisms and chronic illness of depression. Journal of Korean medical science. vol 25. issue 12. 2011-04-07. PMID:21165304. |
we examined the association of serotonin transporter gene polymorphisms with chronicity and recurrent tendency of depression in korean subjects. |
2011-04-07 |
2023-08-12 |
human |
| Ronald M Salomon, Ronald L Cowan, Baxter P Rogers, Mary S Dietrich, Amy Lynn Bauernfeind, Robert M Kessler, John C Gor. Time series fMRI measures detect changes in pontine raphé following acute tryptophan depletion. Psychiatry research. vol 191. issue 2. 2011-04-06. PMID:21236648. |
the omission of tryptophan from an acute tryptophan depletion (atd) diet transiently diminishes serotonin synthesis, alters raphé activity, and mimics symptoms of depression. |
2011-04-06 |
2023-08-12 |
Not clear |
| Glen I Spielmans, Margit I Berman, Ashley N Usital. Psychotherapy versus second-generation antidepressants in the treatment of depression: a meta-analysis. The Journal of nervous and mental disease. vol 199. issue 3. 2011-04-04. PMID:21346483. |
however, a recent meta-analysis found that selective serotonin reuptake inhibitors medications were superior to psychotherapy in the short-term treatment of depression. |
2011-04-04 |
2023-08-12 |
Not clear |
| Yuji Kitaichi, Takeshi Inoue, Shin Nakagawa, Shuken Boku, Aya Kakuta, Takeshi Izumi, Tsukasa Koyam. Sertraline increases extracellular levels not only of serotonin, but also of dopamine in the nucleus accumbens and striatum of rats. European journal of pharmacology. vol 647. issue 1-3. 2011-04-01. PMID:20816814. |
selective serotonin reuptake inhibitors (ssris) are a first-line treatment for depression. |
2011-04-01 |
2023-08-12 |
rat |
| Valeria Carola, Tiziana Pascucci, Stefano Puglisi-Allegra, Simona Cabib, Cornelius Gros. Effect of the interaction between the serotonin transporter gene and maternal environment on developing mouse brain. Behavioural brain research. vol 217. issue 1. 2011-04-01. PMID:20974189. |
a number of studies have demonstrated that the common polymorphism in the serotonin transporter gene (5-htt-lpr) moderates the increased risk for major depression seen in persons exposed to early adverse experiences. |
2011-04-01 |
2023-08-12 |
mouse |
| Jae-Min Kim, Robert Stewart, Sung-Wan Kim, Il-Seon Shin, Su-Jin Yang, Jin-Sang Yoo. Cholesterol and serotonin transporter polymorphism interactions in late-life depression. Neurobiology of aging. vol 32. issue 2. 2011-03-30. PMID:19329228. |
cholesterol and serotonin transporter polymorphism interactions in late-life depression. |
2011-03-30 |
2023-08-12 |
Not clear |
| Jae-Min Kim, Robert Stewart, Sung-Wan Kim, Il-Seon Shin, Su-Jin Yang, Jin-Sang Yoo. Cholesterol and serotonin transporter polymorphism interactions in late-life depression. Neurobiology of aging. vol 32. issue 2. 2011-03-30. PMID:19329228. |
it has been suggested that the functional polymorphism in the serotonin transporter gene linked promoter region (5-httlpr) modifies associations between vascular diseases (coronary artery syndrome or stroke) and depression. |
2011-03-30 |
2023-08-12 |
Not clear |