| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karen L Eskow Jaunarajs, Mariana Angoa-Perez, Donald M Kuhn, Christopher Bisho. Potential mechanisms underlying anxiety and depression in Parkinson's disease: consequences of l-DOPA treatment. Neuroscience and biobehavioral reviews. vol 35. issue 3. 2011-06-01. PMID:20615430. |
though the neurobiological mechanisms remain unclear, recent research contends that l-dopa further perturbs the function of the norepinephrine and serotonin systems, already affected by pd pathology, which have been intimately linked to the development and expression of anxiety and depression. |
2011-06-01 |
2023-08-12 |
Not clear |
| Benedetto Vitiello, Graham Emslie, Gregory Clarke, Karen Dineen Wagner, Joan R Asarnow, Martin B Keller, Boris Birmaher, Neal D Ryan, Betsy Kennard, Taryn L Mayes, Lynn DeBar, Frances Lynch, John Dickerson, Michael Strober, Robert Suddath, James T McCracken, Anthony Spirito, Matthew Onorato, Jamie Zelazny, Giovanna Porta, Satish Iyengar, David A Bren. Long-term outcome of adolescent depression initially resistant to selective serotonin reuptake inhibitor treatment: a follow-up study of the TORDIA sample. The Journal of clinical psychiatry. vol 72. issue 3. 2011-05-31. PMID:21208583. |
long-term outcome of adolescent depression initially resistant to selective serotonin reuptake inhibitor treatment: a follow-up study of the tordia sample. |
2011-05-31 |
2023-08-12 |
human |
| Benedetto Vitiello, Graham Emslie, Gregory Clarke, Karen Dineen Wagner, Joan R Asarnow, Martin B Keller, Boris Birmaher, Neal D Ryan, Betsy Kennard, Taryn L Mayes, Lynn DeBar, Frances Lynch, John Dickerson, Michael Strober, Robert Suddath, James T McCracken, Anthony Spirito, Matthew Onorato, Jamie Zelazny, Giovanna Porta, Satish Iyengar, David A Bren. Long-term outcome of adolescent depression initially resistant to selective serotonin reuptake inhibitor treatment: a follow-up study of the TORDIA sample. The Journal of clinical psychiatry. vol 72. issue 3. 2011-05-31. PMID:21208583. |
we examined the long-term outcome of participants in the treatment of ssri-resistant depression in adolescents (tordia) study, a randomized trial of 334 adolescents (aged 12-18 years) with dsm-iv-defined major depressive disorder initially resistant to selective serotonin reuptake inhibitor (ssri) treatment who were subsequently treated for 12 weeks with another ssri, venlafaxine, another ssri + cognitive-behavioral therapy (cbt), or venlafaxine + cbt. |
2011-05-31 |
2023-08-12 |
human |
| Adam W Oaks, Anita Sidh. Synuclein modulation of monoamine transporters. FEBS letters. vol 585. issue 7. 2011-05-26. PMID:21396366. |
a key regulatory component of monoamine neurotransmission is re-uptake of neurotransmitter by the dopamine transporter, norepinephrine transporter, and serotonin transporter, which are common drug targets in the treatment of depression and other mood disorders. |
2011-05-26 |
2023-08-12 |
Not clear |
| Jan D Andersson, M Edward Pierson, Sjoerd J Finnema, Balázs Gulyás, Richard Heys, Charles S Elmore, Lars Farde, Christer Halldi. Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds. Nuclear medicine and biology. vol 38. issue 2. 2011-05-25. PMID:21315282. |
the serotonin 1b (5-ht(1b)) receptor has been implicated in several psychiatric disorders and is a potential pharmacological target in the treatment of depression. |
2011-05-25 |
2023-08-12 |
monkey |
| Sudhakar Selvaraj, Naga Venkatesha Murthy, Zubin Bhagwagar, Subrata K Bose, Rainer Hinz, Paul M Grasby, Philip J Cowe. Diminished brain 5-HT transporter binding in major depression: a positron emission tomography study with [11C]DASB. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:19756523. |
diminished brain 5-ht transporter binding in major depression: a positron emission tomography study with [11c]dasb. |
2011-05-24 |
2023-08-12 |
Not clear |
| Sudhakar Selvaraj, Naga Venkatesha Murthy, Zubin Bhagwagar, Subrata K Bose, Rainer Hinz, Paul M Grasby, Philip J Cowe. Diminished brain 5-HT transporter binding in major depression: a positron emission tomography study with [11C]DASB. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:19756523. |
the serotonin transporter (5-htt) plays a critical role in the regulation of serotonin neurotransmission and has been implicated in the pathophysiology of major depression. |
2011-05-24 |
2023-08-12 |
Not clear |
| Gregory V Carr, Lee E Schechter, Irwin Luck. Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20217056. |
although selective serotonin reuptake inhibitors (ssris) produce clinical therapeutic effects on depression and anxiety through augmentation of serotonergic neurotransmission, there is little known about the potential contributions of the 5-ht(6) receptor in the treatment of mood disorders. |
2011-05-24 |
2023-08-12 |
rat |
| Felix D C C Beacher, Marcus A Gray, Ludovico Minati, Richard Whale, Neil A Harrison, Hugo D Critchle. Acute tryptophan depletion attenuates conscious appraisal of social emotional signals in healthy female volunteers. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20596858. |
atd thus enables the cognitive effects of serotonin to be studied, with implications for the understanding of psychiatric conditions, including depression. |
2011-05-24 |
2023-08-12 |
human |
| Gregory V Carr, Irwin Luck. The role of serotonin receptor subtypes in treating depression: a review of animal studies. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:21107537. |
serotonin reuptake inhibitors (ssris) are effective in treating depression. |
2011-05-24 |
2023-08-12 |
Not clear |
| Katarina Varnäs, Svante Nyberg, Per Karlsson, M Edward Pierson, Matts Kågedal, Zsolt Cselényi, Dennis McCarthy, Alan Xiao, Minli Zhang, Christer Halldin, Lars Fard. Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:21234549. |
the serotonin 5-ht(1b) receptor is a potential target for the pharmacologic treatment of depression. |
2011-05-24 |
2023-08-12 |
human |
| Yu-Lun Tseng, Meng-Ling Chiang, Tur-Fu Huang, Kuan-Pin Su, Hsien-Yuan Lane, Yu-Chen La. A selective serotonin reuptake inhibitor, citalopram, inhibits collagen-induced platelet aggregation and activation. Thrombosis research. vol 126. issue 6. 2011-05-23. PMID:20961601. |
the antidepressants selective serotonin reuptake inhibitors (ssris) have been found to have cardioprotective effects probably via the attenuation of platelet activation independently in addition to treatment of depression itself. |
2011-05-23 |
2023-08-12 |
Not clear |
| Carmine Pizzi, Anne Wilhelmina Saskia Rutjes, Grazia Maria Costa, Fiorella Fontana, Andrea Mezzetti, Lamberto Manzol. Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease. The American journal of cardiology. vol 107. issue 7. 2011-05-23. PMID:21256471. |
meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease. |
2011-05-23 |
2023-08-12 |
human |
| Carmine Pizzi, Anne Wilhelmina Saskia Rutjes, Grazia Maria Costa, Fiorella Fontana, Andrea Mezzetti, Lamberto Manzol. Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease. The American journal of cardiology. vol 107. issue 7. 2011-05-23. PMID:21256471. |
we carried out a meta-analysis to evaluate the health effects of selective serotonin reuptake inhibitors (ssris) versus placebo or no antidepressants in patients with chd and depression. |
2011-05-23 |
2023-08-12 |
human |
| Britta Haenisch, Heinz Bönisc. Depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters. Pharmacology & therapeutics. vol 129. issue 3. 2011-05-19. PMID:21147164. |
depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters. |
2011-05-19 |
2023-08-12 |
mouse |
| Ramesh K Gupta, Rajeev Kumar, Mark Basset. Interferon-induced depressive illness in hep C patients responds to SSRI antidepressant treatments. Neuropsychiatric disease and treatment. vol 2. issue 3. 2011-05-17. PMID:19412482. |
this paper examines the role of selective serotonin reuptake inhibitors (ssris) in the treatment of hepatitis-c virus (hcv) patients who have developed interferon-alpha induced depression. |
2011-05-17 |
2023-08-12 |
Not clear |
| Mike Briley, Chantal More. Improvement of social adaptation in depression with serotonin and norepinephrine reuptake inhibitors. Neuropsychiatric disease and treatment. vol 6. 2011-05-17. PMID:20957125. |
improvement of social adaptation in depression with serotonin and norepinephrine reuptake inhibitors. |
2011-05-17 |
2023-08-12 |
Not clear |
| Leea H Muhonen, Jari Lahti, Hannu Alho, Jouko Lönnqvist, Jari Haukka, Sirkku T Saarikosk. Serotonin transporter polymorphism as a predictor for escitalopram treatment of major depressive disorder comorbid with alcohol dependence. Psychiatry research. vol 186. issue 1. 2011-05-12. PMID:20800901. |
the aim of this study was to determine whether the serotonin transporter gene polymorphism (5-httlpr) is associated with the treatment outcomes of escitalopram for patients with comorbid major depression and alcohol dependence. |
2011-05-12 |
2023-08-12 |
human |
| Maria Gabriela Sánchez, Erika Estrada-Camarena, Nancy Bélanger, Marc Morissette, Thérèse Di Paol. Estradiol modulation of cortical, striatal and raphe nucleus 5-HT1A and 5-HT2A receptors of female hemiparkinsonian monkeys after long-term ovariectomy. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21144854. |
depression is common in parkinson's disease and an imbalance in serotonin neurotransmission could be implicated. |
2011-05-12 |
2023-08-12 |
monkey |
| Maria Gabriela Sánchez, Erika Estrada-Camarena, Nancy Bélanger, Marc Morissette, Thérèse Di Paol. Estradiol modulation of cortical, striatal and raphe nucleus 5-HT1A and 5-HT2A receptors of female hemiparkinsonian monkeys after long-term ovariectomy. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21144854. |
these results support a role for 17β-estradiol on serotonin activity in parkinson's disease and could be useful for treatment of depression associated with this disease. |
2011-05-12 |
2023-08-12 |
monkey |