| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Louis Albert van den Hove, Daniel Van den Hove, Sissi Brigitte Jakob, Karla-Gerlinde Schraut, Gunter Kenis, Angelika Gertrud Schmitt, Susanne Kneitz, Claus-Jürgen Scholz, Valentina Wiescholleck, Gabriela Ortega, Jos Prickaerts, Harry Steinbusch, Klaus-Peter Lesc. Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions. PloS one. vol 6. issue 8. 2012-02-15. PMID:21857948. |
furthermore, the variation of human serotonin transporter (5-htt, slc6a4) gene was suggested to exert a modulating effect on the association between early life stress and the risk for depression. |
2012-02-15 |
2023-08-12 |
mouse |
| Shilpa Ravinder, Anup G Pillai, Sumantra Chattarj. Cellular correlates of enhanced anxiety caused by acute treatment with the selective serotonin reuptake inhibitor fluoxetine in rats. Frontiers in behavioral neuroscience. vol 5. 2012-02-14. PMID:22232580. |
selective serotonin reuptake inhibitors (ssris) are used extensively in the treatment of depression and anxiety disorders. |
2012-02-14 |
2023-08-12 |
rat |
| Li-ping Chen, Yan Sun, Fa-wei Wang, Dong-mei Duan, Ya-zhuo H. [Effect of Shuyusan on neuropeptide Y and serotonin expression in the hippocampal neurons of rats with chronic mild unpredictable stress-induced depression]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 31. issue 1. 2012-02-13. PMID:21269971. |
[effect of shuyusan on neuropeptide y and serotonin expression in the hippocampal neurons of rats with chronic mild unpredictable stress-induced depression]. |
2012-02-13 |
2023-08-12 |
rat |
| Li-ping Chen, Yan Sun, Fa-wei Wang, Dong-mei Duan, Ya-zhuo H. [Effect of Shuyusan on neuropeptide Y and serotonin expression in the hippocampal neurons of rats with chronic mild unpredictable stress-induced depression]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 31. issue 1. 2012-02-13. PMID:21269971. |
to investigate the effect of shuyusan decoction on neuropeptide y (npy) and serotonin (5-ht) expression in the hippocampus and plasma of rats with chronic mild unpredictable stressors depression. |
2012-02-13 |
2023-08-12 |
rat |
| Esther Molina, Jorge Cervilla, Margarita Rivera, Francisco Torres, Juan Angel Bellón, Berta Moreno, Michael King, Irwin Nazareth, Blanca Gutiérre. Polymorphic variation at the serotonin 1-A receptor gene is associated with comorbid depression and generalized anxiety. Psychiatric genetics. vol 21. issue 4. 2012-02-10. PMID:21512427. |
polymorphic variation at the serotonin 1-a receptor gene is associated with comorbid depression and generalized anxiety. |
2012-02-10 |
2023-08-12 |
Not clear |
| Esther Molina, Jorge Cervilla, Margarita Rivera, Francisco Torres, Juan Angel Bellón, Berta Moreno, Michael King, Irwin Nazareth, Blanca Gutiérre. Polymorphic variation at the serotonin 1-A receptor gene is associated with comorbid depression and generalized anxiety. Psychiatric genetics. vol 21. issue 4. 2012-02-10. PMID:21512427. |
serotonin 1-a receptors are key regulators of serotonin activity and their dysregulation might be implicated in the emergence of both major depression (md) and generalized anxiety disorder (gad). |
2012-02-10 |
2023-08-12 |
Not clear |
| Darakhshan J Halee. Behavioral deficits and exaggerated feedback control over raphe-hippocampal serotonin neurotransmission in restrained rats. Pharmacological reports : PR. vol 63. issue 4. 2012-02-10. PMID:22001976. |
exaggerated feedback control over raphe-hippocampal serotonin neurotransmission may be involved in the inability of the organism to cope with increased stress and elicits behavioral depression. |
2012-02-10 |
2023-08-12 |
rat |
| Eduardo A Pineda, Julie G Hensler, Raman Sankar, Don Shin, Teresa F Burke, Andréy M Mazarat. Plasticity of presynaptic and postsynaptic serotonin 1A receptors in an animal model of epilepsy-associated depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 6. 2012-02-09. PMID:21346733. |
plasticity of presynaptic and postsynaptic serotonin 1a receptors in an animal model of epilepsy-associated depression. |
2012-02-09 |
2023-08-12 |
human |
| Eduardo A Pineda, Julie G Hensler, Raman Sankar, Don Shin, Teresa F Burke, Andréy M Mazarat. Plasticity of presynaptic and postsynaptic serotonin 1A receptors in an animal model of epilepsy-associated depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 6. 2012-02-09. PMID:21346733. |
we examined possible involvement of presynaptic and postsynaptic serotonin 1a (5-ht1a) receptors in epilepsy-associated depression. |
2012-02-09 |
2023-08-12 |
human |
| Boris B Gorzalka, Matthew N Hil. Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 7. 2012-02-08. PMID:21111017. |
specifically, a deficiency in endocannabinoid signaling is sufficient to produce a "depressive-like" phenotype at the preclinical level (including changes in rewarding, emotional and cognitive behavior and biological changes such as increased hpa axis activity, impaired stress adaptation, reduced neurogenesis and altered serotonin negative feedback), and capable of inducing symptoms of depression in humans at a clinical level. |
2012-02-08 |
2023-08-12 |
Not clear |
| Ulf Guenther, Nils U Theuerkauf, Daniel Huse, Michael F Boettcher, Georg Wensing, Christian Putensen, Andreas Hoef. Selective 5-HT(1A)-R-agonist repinotan prevents remifentanil-induced ventilatory depression and prolongs antinociception. Anesthesiology. vol 116. issue 1. 2012-02-06. PMID:22082683. |
selective 5-ht(1a)-r-agonist repinotan prevents remifentanil-induced ventilatory depression and prolongs antinociception. |
2012-02-06 |
2023-08-12 |
Not clear |
| Ulf Guenther, Nils U Theuerkauf, Daniel Huse, Michael F Boettcher, Georg Wensing, Christian Putensen, Andreas Hoef. Selective 5-HT(1A)-R-agonist repinotan prevents remifentanil-induced ventilatory depression and prolongs antinociception. Anesthesiology. vol 116. issue 1. 2012-02-06. PMID:22082683. |
5-ht(1a)-r-agonist repinotan was shown to counteract a morphine-induced ventilatory depression but had pronociceptive effects at small doses (0.2 μg/kg). |
2012-02-06 |
2023-08-12 |
Not clear |
| Stella Bitran, Amy H Farabaugh, Victoria E Ameral, Rachel A LaRocca, Alisabet J Clain, Maurizio Fava, David Mischoulo. Do early changes in the HAM-D-17 anxiety/somatization factor items affect the treatment outcome among depressed outpatients? Comparison of two controlled trials of St John's wort (Hypericum perforatum) versus a SSRI. International clinical psychopharmacology. vol 26. issue 4. 2012-02-02. PMID:21278577. |
to assess whether early changes in hamilton depression rating scale-17 anxiety/somatization items predict remission in two controlled studies of hypericum perforatum (st john's wort) versus selective serotonin reuptake inhibitors for major depressive disorder. |
2012-02-02 |
2023-08-12 |
Not clear |
| Diogo Azevedo Oliveira Sennfelt, Maria Alice Rodrigues Marques da Silva, Anabela Pereira da Silva Tavare. Bupropion in the treatment of major depressive disorder in real-life practice. Clinical drug investigation. vol 31 Suppl 1. 2012-02-02. PMID:22015859. |
this article highlights the use of bupropion in the treatment of three patients with varying presentations of mdd, including as combination therapy in a patient refractory to treatment with a selective serotonin reuptake inhibitor, monotherapy in a patient with somatic symptoms of depression and loss of libido, and in a patient complaining of anxiety as a symptom of mdd. |
2012-02-02 |
2023-08-12 |
Not clear |
| Sean Phipps, Kelly E Buckholdt, Laly Fernandez, Lori Wiener, Mary Jo Kupst, Avi Madan-Swain, Larry Mullins, Rhonda Robert, Olle Jane Sahler, Nicole Vincent, Robert B Nol. Pediatric oncologists' practices of prescribing selective serotonin reuptake inhibitors (SSRIs) for children and adolescents with cancer: a multi-site study. Pediatric blood & cancer. vol 58. issue 2. 2012-01-31. PMID:21284076. |
to survey pediatric oncologists regarding prescription of selective serotonin reuptake inhibitors (ssris) and related medications for the treatment of depression and anxiety disorders in children with cancer. |
2012-01-31 |
2023-08-12 |
Not clear |
| Pedro J Modreg. Depression in Alzheimer's disease. Pathophysiology, diagnosis, and treatment. Journal of Alzheimer's disease : JAD. vol 21. issue 4. 2012-01-31. PMID:21504132. |
depression may predate dementia and tends to occur in up to 50% of ad patients with a decrease of noradrenalin and serotonin in the brain being the most plausible cause. |
2012-01-31 |
2023-08-12 |
Not clear |
| Pedro J Modreg. Depression in Alzheimer's disease. Pathophysiology, diagnosis, and treatment. Journal of Alzheimer's disease : JAD. vol 21. issue 4. 2012-01-31. PMID:21504132. |
both tricyclic antidepressants and selective serotonin reuptake inhibitors are better than placebo in treating depression in ad (weighted or: 1.82, 95% ci: 1.13-2.96), with sertraline being one of the most used drugs. |
2012-01-31 |
2023-08-12 |
Not clear |
| Marielle Hess, Georg Höfner, Klaus T Wanne. (S)- and (R)-fluoxetine as native markers in mass spectrometry (MS) binding assays addressing the serotonin transporter. ChemMedChem. vol 6. issue 10. 2012-01-26. PMID:21793219. |
a recently established and validated lc-esi-ms/ms method for quantification of fluoxetine was used to implement ms binding assays for the human serotonin transporter (hsert)-the primary target in the treatment of depression and emotional disorders. |
2012-01-26 |
2023-08-12 |
human |
| Rudolf Uher, Avshalom Caspi, Renate Houts, Karen Sugden, Benjamin Williams, Richie Poulton, Terrie E Moffit. Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. Journal of affective disorders. vol 135. issue 1-3. 2012-01-25. PMID:21439648. |
serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. |
2012-01-25 |
2023-08-12 |
Not clear |
| Rupert Lanzenberger, Markus Mitterhauser, Georg S Kranz, Christoph Spindelegger, Wolfgang Wadsak, Patrycja Stein, Ulrike Moser, Markus Savli, Kurt Kletter, Siegfried Kaspe. Progesterone level predicts serotonin-1a receptor binding in the male human brain. Neuroendocrinology. vol 94. issue 1. 2012-01-18. PMID:21606641. |
alterations of the inhibitory serotonin-1a (5-ht(1a)) receptor distribution are associated with depression and anxiety. |
2012-01-18 |
2023-08-12 |
human |